R A Towner

Summary

Affiliation: Oklahoma Medical Research Foundation
Country: USA

Publications

  1. ncbi In vivo detection of c-Met expression in a rat C6 glioma model
    R A Towner
    Small Animal MRI Core Facility, Oklahoma City, OK, USA
    J Cell Mol Med 12:174-86. 2008
  2. ncbi Molecular magnetic resonance imaging approaches used to aid in the understanding of angiogenesis in vivo: implications for tissue engineering
    Rheal A Towner
    Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma 73104, USA
    Tissue Eng Part A 16:357-64. 2010
  3. ncbi In vivo detection of inducible nitric oxide synthase in rodent gliomas
    Rheal A Towner
    Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA
    Free Radic Biol Med 48:691-703. 2010
  4. ncbi Non-mammalian fat-1 gene prevents neoplasia when introduced to a mouse hepatocarcinogenesis model: Omega-3 fatty acids prevent liver neoplasia
    J Griffitts
    Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA
    Biochim Biophys Acta 1801:1133-44. 2010
  5. ncbi In vivo MRS assessment of altered fatty acyl unsaturation in liver tumor formation of a TGF alpha/c-myc transgenic mouse model
    J Griffitts
    Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA
    J Lipid Res 50:611-22. 2009
  6. ncbi Application of proton NMR spectroscopy in the study of lipid metabolites in a rat hepatocarcinogenesis model
    Y A Tesiram
    Oklahoma Medical Research Foundation, Free Radical Biology and Aging Research Program, 825 NE 13th St, Oklahoma City, OK 73104, USA
    Biochim Biophys Acta 1737:61-8. 2005
  7. ncbi In vivo image-guided (1)H-magnetic resonance spectroscopy of the serial development of hepatocarcinogenesis in an experimental animal model
    L M Foley
    North Queensland Magnetic Resonance Centre, Department of Physiology and Pharmacology, James Cook University, Townsville, Australia
    Biochim Biophys Acta 1526:230-6. 2001
  8. ncbi In vivo detection of aflatoxin-induced lipid free radicals in rat bile
    R A Towner
    North Queensland Magnetic Resonance Centre and Department of Physiology and Pharmacology, School of Biomedical Sciences, Molecular Sciences Building, James Cook University, Townsville 4811 Queensland, Australia
    Biochim Biophys Acta 1573:55-62. 2002

Collaborators

  • S Liu
  • J X Kang
  • J Griffitts
  • D Saunders
  • Y A Tesiram
  • G E Reid
  • L M Foley
  • A Salih
  • J V Busik
  • T A Lydic
  • R A Floyd
  • Y Tesiram
  • D M Painter

Detail Information

Publications8

  1. ncbi In vivo detection of c-Met expression in a rat C6 glioma model
    R A Towner
    Small Animal MRI Core Facility, Oklahoma City, OK, USA
    J Cell Mol Med 12:174-86. 2008
    ..Controls with no Ab or with a normal rat IgG attached to the contrast agent component indicated no non-specific binding to glioma tissue. This is the first successful visualization of in vivo overexpression of c-Met in gliomas...
  2. ncbi Molecular magnetic resonance imaging approaches used to aid in the understanding of angiogenesis in vivo: implications for tissue engineering
    Rheal A Towner
    Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma 73104, USA
    Tissue Eng Part A 16:357-64. 2010
    ..VEGF-R2 levels in tumor tissues were also confirmed in western blots and via immunohistochemistry. Based on our results, in vivo evaluation of tissue angiogenesis using molecular MRI is possible in tissue engineering applications...
  3. ncbi In vivo detection of inducible nitric oxide synthase in rodent gliomas
    Rheal A Towner
    Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA
    Free Radic Biol Med 48:691-703. 2010
    ..In vivo assessment of iNOS levels associated with tumor development is quite feasible in heterogeneous tissues with mMRI...
  4. ncbi Non-mammalian fat-1 gene prevents neoplasia when introduced to a mouse hepatocarcinogenesis model: Omega-3 fatty acids prevent liver neoplasia
    J Griffitts
    Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA
    Biochim Biophys Acta 1801:1133-44. 2010
    ..Endogenous omega-3 fatty acids were found to prevent HCC development in mice...
  5. ncbi In vivo MRS assessment of altered fatty acyl unsaturation in liver tumor formation of a TGF alpha/c-myc transgenic mouse model
    J Griffitts
    Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA
    J Lipid Res 50:611-22. 2009
    ....
  6. ncbi Application of proton NMR spectroscopy in the study of lipid metabolites in a rat hepatocarcinogenesis model
    Y A Tesiram
    Oklahoma Medical Research Foundation, Free Radical Biology and Aging Research Program, 825 NE 13th St, Oklahoma City, OK 73104, USA
    Biochim Biophys Acta 1737:61-8. 2005
    ..The results of this study are in agreement with those previously published in the literature on other rat hepatocarcinogenesis models...
  7. ncbi In vivo image-guided (1)H-magnetic resonance spectroscopy of the serial development of hepatocarcinogenesis in an experimental animal model
    L M Foley
    North Queensland Magnetic Resonance Centre, Department of Physiology and Pharmacology, James Cook University, Townsville, Australia
    Biochim Biophys Acta 1526:230-6. 2001
    ..It is anticipated that this model will precede the application of the same technology to the non-invasive diagnosis and grading of human hepatocellular carcinoma...
  8. ncbi In vivo detection of aflatoxin-induced lipid free radicals in rat bile
    R A Towner
    North Queensland Magnetic Resonance Centre and Department of Physiology and Pharmacology, School of Biomedical Sciences, Molecular Sciences Building, James Cook University, Townsville 4811 Queensland, Australia
    Biochim Biophys Acta 1573:55-62. 2002
    ..This indicates that oxidation of AFB1 generates free radical species via CYP metabolism and an iron-mediated redox mechanism...