Carol L Shields

..To evaluate fluorescein angiography (FA) findings after intra-arterial chemotherapy (IAC) for retinoblastoma...

..To study the effect of intraarterial chemotherapy (IAC) on retinoblastoma-induced retinal detachment...

..To evaluate iris melanoma in children versus adults...

..To report the spectrum of iris lesions based on patient age at presentation...

..To evaluate the efficacy of topical interferon alfa-2b in the management of ocular surface squamous neoplasia (OSSN)...

..These tractional features are not often found in Coats' disease treated with standard measures without bevacizumab. Caution is advised in the use of bevacizumab for patients with Coats' disease...

..To assess the efficacy of less than 3 cycles of intra-arterial chemotherapy (IAC) for retinoblastoma...

..Currently, the most important mutation proves to be chromosome 3 monosomy, an abnormality associated with greater risk for metastatic disease...

..To evaluate regression rates after plaque radiotherapy and thermotherapy of uveal melanoma with chromosome 3 monosomy versus disomy...

..To describe 5 patients with pigmented conjunctival squamous cell carcinoma in situ...

..To describe the autofluorescence features of choroidal nevi...

..To evaluate the clinical features of choroidal nevi based on patient age at presentation and to investigate features of the nevi that are predictive of patient symptoms...

..To describe the autofluorescence features of orange pigment (intracellular lipofuscin) overlying small presumed choroidal melanomas...

..To describe the autofluorescence features of CHRPE...

..To evaluate visual acuity in eyes with choroidal nevus...

..To report three cases of bilateral primary choroidal melanoma treated with bilateral plaque radiotherapy...

..To report bilateral plasmacytoma of the ciliary body in a healthy patient...

..To evaluate the presence of chromosome 3 monosomy in small choroidal melanoma using fine-needle aspiration biopsy (FNAB)...

..To evaluate the feasibility of genetic testing of uveal melanoma using fine-needle aspiration biopsy (FNAB)...

..Numerous conjunctival tumors can occur in children, originating from tissues of choristomatous, epithelial, melanocytic, vascular, fibrous, xanthomatous and lymphoid. Overall, 97% prove to be benign and only 3% are malignant...

..To evaluate the retinal status overlying choroidal osteoma using optical coherence tomography (OCT)...

..To describe the autofluorescence features of choroidal melanoma...

..To evaluate the clinical features and management of diffuse infiltrating retinoblastoma...

..To evaluate visual outcome of eyes with combined hamartoma of the retina and retinal pigment epithelium (RPE)...

..Eyelid and primary orbital melanoma are the least common variants. Early diagnosis from annual ocular examination by an experienced ophthalmologist and treatment strategies are reviewed...

..To determine features that are predictive of growth of choroidal nevi into melanoma...

..To describe sector (partial) involvement of the uvea with melanocytosis...

..To describe the features of phacomatosis pigmentovascularis (cesioflammea type)...

..To describe tumor control following intra-arterial chemotherapy (IAC) for retinoblastoma...

..To describe treatment complications following intra-arterial chemotherapy (IAC) for retinoblastoma...

..To describe the clinical features of iridocorneal endothelial (ICE) syndrome in a group of patients referred because of suspected iris melanoma...

..To determine the incidence of Chromosome 3 monosomy in iris melanoma using fine needle aspiration biopsy...

..25 mg/0.05 mL) resolved the iris neovascularization, and plaque radiotherapy (brachytherapy) resolved the mass rapidly and completely, preserving the patient's visual acuity and preventing glaucoma during the 10-month follow-up...

..To evaluate conjunctival nevi using anterior segment optical coherence tomography (AS-OCT)...

..To evaluate choroidal halo nevus...

..Despite its allure, intra-arterial chemotherapy should be used with caution, as in other fields of paediatric oncology it has been found to provide no advantage over intravenous chemotherapy. Time will tell...

..To provide an update on current management of retinoblastoma..

..To describe 4 patients with choroidal vitiligo masquerading as large choroidal nevus...

..To determine the rate of metastasis of uveal melanoma on the basis of tumor thickness in millimeters...

..To evaluate retinoblastoma regression patterns following chemoreduction and adjuvant therapy...

..To evaluate the clinical features and outcomes of eyes with peripheral exudative hemorrhagic chorioretinopathy (PEHCR) simulating choroidal melanoma...

..To evaluate chemoreduction (CRD) for group E retinoblastoma...

..Purpose  To determine the efficacy of postenucleation adjuvant chemotherapy with vincristine, etoposide, and carboplatin in the prevention of metastasis for patients with high-risk retinoblastoma...

..To present a simplified approach to management of retinoblastoma using basic clinical features...

..Therefore, ophthalmologists should be aware of the important factors that identify small choroidal melanoma so that early treatment and better life prognosis can be achieved for their patients...

..To evaluate tumor control and treatment complications following plaque radiotherapy combined with transpupillary thermotherapy for choroidal melanoma...

..To evaluate conservative management of unilateral retinoblastoma using chemoreduction and focal treatment...

..To evaluate the effectiveness of chemoreduction alone and chemoreduction with thermotherapy for macular retinoblastoma...

..To describe the clinical features and management of extensive ocular surface squamous neoplasia (OSSN) (squamous cell carcinoma) of the socket...

..To evaluate the occurrence of new retinoblastomas in patients treated with 6 cycles of chemoreduction...

..To describe recent advances in the management of choroidal melanoma...

..Retinoblastoma is a highly malignant tumor of the eye that manifests most often in the first 3 years of life...

..To evaluate retinoblastoma control following chemoreduction...

..Therefore, ophthalmologists should be aware of the clinical factors that identify small choroidal melanoma so that early treatment and better prognosis can be achieved for their patients...

..To document 2 cases of progressively enlarging retinal astrocytoma that caused exudative retinal detachment, vitreous hemorrhage, and tumor seeding, simulating retinoblastoma in 1 case and choroidal melanoma in the other...

..To evaluate choroidal osteoma for tumor growth, tumor decalcification, related choroidal neovascularization, visual acuity loss, and poor visual acuity...

..To evaluate whether neoadjuvant intravenous chemotherapy (chemoreduction) for retinoblastoma reduces the risk for associated intracranial neuroblastic tumor (trilateral retinoblastoma)...

..To evaluate the efficacy of topical mitomycin C for extensive recurrent conjunctival and corneal squamous cell carcinoma (SCC)...

..To illustrate a novel method of management for extensive conjunctival and corneal melanoma...

..The current classification and management strategies for retinoblastoma are discussed...

..To evaluate tumor control with plaque radiotherapy for juxtapapillary choroidal melanoma that overhangs the optic disc...

..The long-term effects remain unknown...

..Globe salvage is usually achieved despite tumor recurrence...

..To report the results of chemoreduction and focal therapy for retinoblastoma with determination of factors predictive of the need for treatment with external beam radiotherapy or enucleation...

..To evaluate the time of onset and risk factors for the development of macular edema following plaque radiotherapy for uveal melanoma, using optical coherence tomography (OCT)...

..To report the development of retinal break or rhegmatogenous retinal detachment (RRD) after transpupillary thermotherapy (TTT) as primary or adjunct treatment of choroidal melanoma...

..Complications such as radiation retinopathy and mild vitreous hemorrhage should be anticipated, depending on the location, size, and extent of the tumor...

..Excisional biopsy revealed an amelanotic melanoma of the conjunctiva with superficial orbital invasion. There has been no tumor recurrence during 20 months of follow-up...

..Retinal tumor and subretinal seed recurrence seems to manifest within 3 years of follow-up. Close follow-up of all patients treated with chemoreduction is warranted...

..CONCLUSIONS: The ICRB can be of assistance in predicting CRD success for retinoblastoma. Additional treatment methods are necessary to salvage more group D eyes...

..CONCLUSION: The clinical factors that predicted visual acuity of 20/40 or better were a tumor margin at least 3 mm from the foveola and optic disc and an absence of subretinal fluid...

..Evaluation of clinical features and natural course of giant choroidal nevi (diameter >or=10 mm)...

..Despite the lack of viable-appearing retinoblastoma within the main tumor, enucleation was performed for viable subretinal and/or vitreous seeds in 7 cases and confirmed histopathologically...

..The purpose of this study was to describe the autofluorescence (AF) features of choroidal hemangioma in 34 consecutive patients...

..In conclusion, multifocal choroidal melanoma is rare and may be related to underlying ocular melanocytosis...

..Transpupillary thermotherapy can cause damaging effects to the retina, leading to visual loss shortly after treatment...

..A diagnosis of nodular posterior scleritis was made and the minimally symptomatic patient without ocular pain was observed unless symptoms progressed. In this case, certain clinical features led to the proper diagnosis...

..Tumor control is 92% at 5 years, but related complications, especially cataract and elevated intraocular pressure, should be anticipated...

..More extensive retinal damage occurred with applications that used energy levels higher than what have been used in the clinical setting or when the fundus was more heavily pigmented...

..The large intraocular mass and associated features and radiation complications led to poor visual acuity in most patients. At 10 years follow-up, enucleation was necessary in 34% of patients, and metastasis developed in 55% of patients...

..The eye was enucleated, and metastatic evaluation remained negative at 5 years' follow-up. This unusual case, confirmed histopathologically, reveals that young patients with melanocytoma can have malignant transformation at an early age...

..To report a case of a choroidal melanoma that presented with painful scleritis and choroidal effusion...

..Photodynamic therapy of choroidal hemangioma may be effective in resolving associated cystoid macular edema and improving visual acuity...

..To evaluate the feasibility of genetic testing of uveal melanoma using fine-needle aspiration biopsy (FNAB)...

..CONCLUSIONS: Intravitreal triamcinolone acetonide can stabilize or improve visual acuity in some patients with radiation-induced maculopathy, but its effect might not be lasting...

..To report the efficacy of iodine I 125 plaque radiotherapy for the treatment of vasoproliferative tumors (VPTs) of the ocular fundus...

..To evaluate the clinical features and risks for transformation of conjunctival primary acquired melanosis (PAM) into melanoma...

..To report results of plaque radiotherapy for choroidal melanoma that completely encircles the optic disc (circumpapillary melanoma)...

..In this case, the classic cutaneous manifestations combined with the fine linear hypopigmented RPE foci were important in suggesting the diagnosis of IP...

..CONCLUSIONS: Using OCT, overlying retinal thinning and photoreceptor loss directly over CHRPE was found in 10 consecutive patients. These findings likely account for related visual field loss...

..To describe the clinical features and management of ocular surface squamous neoplasia (OSSN) after corneal graft...

..To investigate the potential benefit of periocular depot triamcinolone in the prevention of macular edema after iodine 125 plaque radiotherapy for uveal melanoma...

..CONCLUSION: Cavitation can occur in ciliary body melanoma and can lead to misinterpretation as a cyst. Cavitary melanoma should be considered in the differential diagnosis of cystic lesions of the anterior segment...