Susan C Hubchak

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. ncbi Cytoskeletal rearrangement and signal transduction in TGF-beta1-stimulated mesangial cell collagen accumulation
    Susan C Hubchak
    Department of Pediatrics, Northwestern University Medical School, Chicago, Illinois, USA
    J Am Soc Nephrol 14:1969-80. 2003
  2. ncbi Rac1 promotes TGF-beta-stimulated mesangial cell type I collagen expression through a PI3K/Akt-dependent mechanism
    Susan C Hubchak
    Division of Kidney Diseases, Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Am J Physiol Renal Physiol 297:F1316-23. 2009
  3. ncbi TGF-beta signal transduction in chronic kidney disease
    H William Schnaper
    Division of Kidney Diseases, Department of Pediatrics, Northwestern University Feinberg School of Medicine, 303 E Chicago Ave Chicago, IL 60611 3008, USA
    Front Biosci 14:2448-65. 2009
  4. ncbi TGF-beta signal transduction and mesangial cell fibrogenesis
    H William Schnaper
    Division of Kidney Diseases, Department of Pediatrics, The Feinberg School of Medicine of Northwestern University, and Children s Memorial Institute for Education and Research, Chicago, Illinois 60611 3008, USA
    Am J Physiol Renal Physiol 284:F243-52. 2003
  5. ncbi A conceptual framework for the molecular pathogenesis of progressive kidney disease
    H William Schnaper
    Division of Kidney Diseases, Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Pediatr Nephrol 25:2223-30. 2010

Detail Information

Publications5

  1. ncbi Cytoskeletal rearrangement and signal transduction in TGF-beta1-stimulated mesangial cell collagen accumulation
    Susan C Hubchak
    Department of Pediatrics, Northwestern University Medical School, Chicago, Illinois, USA
    J Am Soc Nephrol 14:1969-80. 2003
    ..Thus, TGF-beta1-mediated collagen I accumulation is associated with cytoskeletal rearrangement and Rho-GTPase signaling...
  2. ncbi Rac1 promotes TGF-beta-stimulated mesangial cell type I collagen expression through a PI3K/Akt-dependent mechanism
    Susan C Hubchak
    Division of Kidney Diseases, Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Am J Physiol Renal Physiol 297:F1316-23. 2009
    ....
  3. ncbi TGF-beta signal transduction in chronic kidney disease
    H William Schnaper
    Division of Kidney Diseases, Department of Pediatrics, Northwestern University Feinberg School of Medicine, 303 E Chicago Ave Chicago, IL 60611 3008, USA
    Front Biosci 14:2448-65. 2009
    ..Studies of these mechanisms in kidney cells and in whole-animal experimental models, reviewed here, are beginning to provide insight into the role of TGF-beta in the pathogenesis of renal dysfunction and its potential treatment...
  4. ncbi TGF-beta signal transduction and mesangial cell fibrogenesis
    H William Schnaper
    Division of Kidney Diseases, Department of Pediatrics, The Feinberg School of Medicine of Northwestern University, and Children s Memorial Institute for Education and Research, Chicago, Illinois 60611 3008, USA
    Am J Physiol Renal Physiol 284:F243-52. 2003
    ..Further investigation of these multiple interactions will provide insight into possible ways to interrupt cellular mechanisms of glomerular fibrogenesis...
  5. ncbi A conceptual framework for the molecular pathogenesis of progressive kidney disease
    H William Schnaper
    Division of Kidney Diseases, Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Pediatr Nephrol 25:2223-30. 2010
    ..Application of this schema could have significant relevance to both research inquiry and clinical practice...