Research Topics
| A S BordersSummaryAffiliation: Northwestern University Country: USA Publications
| Collaborators
|
Detail Information
Publications
Macrophage-mediated neuroprotection and neurogenesis in the olfactory epitheliumA S Borders
Department of Physiology, University of Kentucky College of Medicine, Kentucky, USA
Physiol Genomics 31:531-43. 2007..These results identified the differential regulation of several novel genes through which alternatively activated macrophages regulate OSN progenitor cell proliferation, differentiation, and maturation, and the survival of OSNs...
The p38alpha mitogen-activated protein kinase as a central nervous system drug discovery targetAaron S Borders
Center for Drug Discovery and Chemical Biology, Northwestern University, Chicago, IL 60611, USA
BMC Neurosci 9:S12. 2008..Development of bioavailable, central nervous system-penetrant p38alpha MAPK inhibitors provides the required foundation for drug discovery campaigns targeting p38alpha MAPK in neurodegenerative disorders...
Temporal gene expression profiles of target-ablated olfactory epithelium in mice with disrupted expression of scavenger receptor A: impact on macrophagesM L Getchell
Department of Anatomy and Neurobiology, University of Kentucky College of Medicine, Lexington, Kentucky, USA
Physiol Genomics 27:245-63. 2006..These studies suggest that impairment of the immune response to OBX in the OE of MSR-/- mice most likely resulted from decreased m adhesion and subsequent reduced infiltration and activation, with a resultant decrease in neurogenesis...
