SLAVA SIMON EPSTEINSummaryAffiliation: Northeastern University Country: USA Publications
Research Grants
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Detail Information
Publications
Microbial scout hypothesis, stochastic exit from dormancy, and the nature of slow growersS Buerger
Address correspondence to S S Epstein
Appl Environ Microbiol 78:3221-8. 2012..The stochasticity of awakening can also provide a parsimonious explanation to several microbiological observations, including the apparent randomness of latent infections and the existence of viable-but-nonculturable cells (VBNC)...
Microbial scout hypothesis and microbial discoveryS Buerger
Address correspondence to S S Epstein
Appl Environ Microbiol 78:3229-33. 2012..e., single-cell cultivation, may still be the method of choice. While it does not necessarily allow more species to grow from a given inoculum, it minimizes the overall isolation effort and supplies needed...
Environmental rRNA inventories miss over half of protistan diversitySunok Jeon
Department of Environmental Science, Kangwon National University, Kangwon Do, Korea
BMC Microbiol 8:222. 2008..Here we attempt to discriminate between these possibilities by statistically analysing four protistan inventories obtained using different general eukaryotic PCR primers...
Short peptide induces an "uncultivable" microorganism to grow in vitroD Nichols
Department of Biology, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA
Appl Environ Microbiol 74:4889-97. 2008..Access to cultures of some of these species should be possible through identification of the signaling compounds necessary for growth, their addition to standard medium formulations, and eventual domestication...
New approaches for isolation of previously uncultivated oral bacteriaM V Sizova
Department of Biology, Northeastern University, Boston, Massachusetts, USA
Appl Environ Microbiol 78:194-203. 2012..We conclude that the ensemble of new methods we introduced will likely help close the gap between cultivated and uncultivated species from the human oral cavity...
Isolating "uncultivable" microorganisms in pure culture in a simulated natural environmentT Kaeberlein
Biology Department, Northeastern University, Boston, MA 02115, USA
Science 296:1127-9. 2002..These isolates did not grow on artificial media alone but formed colonies in the presence of other microorganisms. This observation may help explain the nature of microbial uncultivability...
Synthetic statistical approach reveals a high degree of richness of microbial eukaryotes in an anoxic water columnS-O Jeon
Department of Biology, Northeastern University, Boston, MA 02115, USA
Appl Environ Microbiol 72:6578-83. 2006..These estimates are among the first for microbial eukaryotes that are obtained using state-of-the-art statistical methods and can serve as benchmark numbers for the local diversity of protists...
Use of ichip for high-throughput in situ cultivation of "uncultivable" microbial speciesD Nichols
134 Mugar Hall, Department of Biology, Northeastern University, 360 Huntington Ave, Boston, MA 02115, USA
Appl Environ Microbiol 76:2445-50. 2010..The new method allows access to a large and diverse array of previously inaccessible microorganisms and is well suited for both fundamental and applied research...
Research Grants
- Cultivating the 'uncultivable' oral microfloraSlava Epstein; Fiscal Year: 2007..This will lead to identifying previously unknown microorganisms that impact human health, and will lay the basis for development of improved therapeutics against oral pathogens. ..
