Research Topics
| J J DochertySummaryAffiliation: Northeastern Ohio Universities College of Medicine Country: USA Publications
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Publications
Resveratrol inhibition of herpes simplex virus replicationJ J Docherty
Department of Microbiology and Immunology, Northeastern Ohio Universities College of Medicine, Rootstown 44272, USA
Antiviral Res 43:145-55. 1999..These results suggest that a critical early event in the viral replication cycle, that has a compensatory cellular counterpart, is being adversely affected...- Effect of topically applied resveratrol on cutaneous herpes simplex virus infections in hairless miceJohn J Docherty
Department of Microbiology Immunology, Northeastern Ohio Universities, College of Medicine, PO Box 95, State Route 44, Rootstown, OH 44272, USA
Antiviral Res 61:19-26. 2004..These studies demonstrate that topically applied resveratrol inhibits HSV lesion formation in the skin of mice... - Effect of resveratrol on herpes simplex virus vaginal infection in the mouseJohn J Docherty
Department of Microbiology Immunology, Northeastern Ohio Universities College of Medicine, 4209 State Route 44, Rootstown, OH 44272, USA
Antiviral Res 67:155-62. 2005..5% resveratrol-treated animals was 24%, and 19% resveratrol-treated animals was 3%. Collectively, these results demonstrate that resveratrol cream inhibits or reduces HSV replication in the vagina of mice and limits extravaginal disease... - Resveratrol inhibition of varicella-zoster virus replication in vitroJohn J Docherty
Northeastern Ohio Universities College of Medicine, P O Box 95, Rootstown, OH 44272, USA
Antiviral Res 72:171-7. 2006..These results demonstrate that VZV replication is adversely affected by resveratrol which is negatively impacting IE62 synthesis... - Resveratrol inhibition of Propionibacterium acnesJohn J Docherty
Department of Microbiology, Immunology and Biochemistry, Northeastern Ohio Universities College of Medicine, Rootstown, OH 44272, USA
J Antimicrob Chemother 59:1182-4. 2007..To evaluate the effects of the anti-inflammatory hydroxystilbene, resveratrol, on Propionibacterium acnes growth... - Resveratrol suppresses nuclear factor-kappaB in herpes simplex virus infected cellsSeth A Faith
Department of Microbiology, Immunology and Biochemistry, Northeastern Ohio Universities College of Medicine, Rootstown, OH 44272, USA
Antiviral Res 72:242-51. 2006..Cumulatively, these data indicate that resveratrol (i) suppresses HSV induced activation of NF-kappaB within the nucleus and (ii) impairs expression of essential immediate-early, early and late HSV genes and synthesis of viral DNA... - The ability of an HSV strain to initiate zosteriform spread correlates with its neuroinvasive disease potentialN Goel
Northeastern Ohio Universities College of Medicine, Rootstown 44272, USA
Arch Virol 147:763-73. 2002..In conclusion, the viral properties which are important for neuroinvasiveness appear to also determine the ability of an HSV strain to cause zosteriform disease... - A modification of the epidermal scarification model of herpes simplex virus infection to achieve a reproducible and uniform progression of diseaseNeena Goel
Department of Microbiology/Immunology, Northeastern Ohio Universities, College of Medicine, 4209 State Route 44, Box 95, Rootstown, OH 44272, USA
J Virol Methods 106:153-8. 2002.... - Innate and adaptive host response during the initial phase of herpes simplex virus encephalitis in the neonatal mouseGuttalu K Kumaraswamy
Department of Microbiology, Immunology and Biochemistry, Northeastern Ohio Universities College of Medicine, Rootstown, Ohio 44272, USA
J Neurovirol 12:365-74. 2006..B and T lymphocytes were not detected on day 1 through 7 post infection. This controlled experimental HSV infection suggests a limited non-specific early host response in the neonate to HSV encephalitis...