Research Topics
| Anupam BishayeeSummaryAffiliation: Northeastern Ohio Universities College of Medicine Country: USA Publications
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Detail Information
Publications
Triterpenoids as potential agents for the chemoprevention and therapy of breast cancerAnupam Bishayee
Cancer Therapeutics and Chemoprevention Group, Department of Pharmaceutical Sciences, Northeastern Ohio Universities Colleges of Medicine and Pharmacy, 4209 State Route 44, Rootstown, OH 44272, USA
Front Biosci 16:980-96. 2011..Potential challenges and future directions involved in the advancement of these promising compounds in the prevention and therapy of human breast cancer are also identified...
Anthocyanin-rich black currant extract suppresses the growth of human hepatocellular carcinoma cellsAnupam Bishayee
Cancer Therapeutics and Chemoprevention Group, Department of Pharmaceutical Sciences, Northeastern Ohio Universities Colleges of Medicine and Pharmacy, 4209 State Route 44, Rootstown, OH 44272, USA
Nat Prod Commun 5:1613-8. 2010..This product could be useful in the prevention and treatment of human hepatocellular carcinoma...
Pomegranate-mediated chemoprevention of experimental hepatocarcinogenesis involves Nrf2-regulated antioxidant mechanismsAnupam Bishayee
Cancer Therapeutics and Chemoprevention Group, Department of Pharmaceutical Sciences, Northeastern Ohio Universities Colleges of Medicine and Pharmacy, OH 44272, USA
Carcinogenesis 32:888-96. 2011..The outcome of this study strongly supports the development of pomegranate-derived products in the prevention and treatment of human HCC, which remains a devastating disease...
Resveratrol and liver disease: from bench to bedside and communityAnupam Bishayee
Department of Pharmaceutical Sciences, Northeastern Ohio Universities Colleges of Medicine and Pharmacy, Rootstown, OH, USA
Liver Int 30:1103-14. 2010..The challenges involved, future directions and novel approaches such as site-specific drug delivery in the use of resveratrol for the prevention and treatment of liver disease are also discussed...
Suppression of the inflammatory cascade is implicated in resveratrol chemoprevention of experimental hepatocarcinogenesisAnupam Bishayee
Department of Pharmaceutical Sciences Cancer Therapeutics and Chemoprevention Emphasis Group, Northeastern Ohio Universities Colleges of Medicine and Pharmacy, 4209 State Route 44, Rootstown Ohio, 44272, USA
Pharm Res 27:1080-91. 2010..The current study was designed to explore whether the antiinflammatory properties of resveratrol play a role in its antihepatocarcinogenic action...
Vanadium in the detection, prevention and treatment of cancer: the in vivo evidenceAnupam Bishayee
Department of Pharmaceutical Sciences, Northeastern Ohio Universities Colleges of Medicine and Pharmacy, 4209 State Route 44, Rootstown, OH 44272, United States
Cancer Lett 294:1-12. 2010..Supporting and challenging evidence as well as future directions of vanadium research exploring the possibility of using this dietary agent for detection, prevention and treatment of human cancers are critically discussed...
Resveratrol suppresses oxidative stress and inflammatory response in diethylnitrosamine-initiated rat hepatocarcinogenesisAnupam Bishayee
Department of Pharmaceutical Sciences, Northeastern Ohio Universities Colleges of Medicine and Pharmacy, Rootstown, 44272, USA
Cancer Prev Res (Phila) 3:753-63. 2010..The outcome of this study may benefit the development of resveratrol in the prevention and intervention of human HCC...
Anthocyanin-rich black currant (Ribes nigrum L.) extract affords chemoprevention against diethylnitrosamine-induced hepatocellular carcinogenesis in ratsAnupam Bishayee
Department of Pharmaceutical Sciences, Northeastern Ohio Universities Colleges of Medicine and Pharmacy, Rootstown, OH 44272, USA
J Nutr Biochem 22:1035-46. 2011..These results along with a safety profile of BCSE encourage the development of black currant bioactive constituents as chemopreventive agents for human liver cancer...
d -Limonene sensitizes docetaxel-induced cytotoxicity in human prostate cancer cells: Generation of reactive oxygen species and induction of apoptosisThangaiyan Rabi
Department of Pharmaceutical Sciences, Northeastern Ohio Universities Colleges of Medicine and Pharmacy, 4209 State Route 44, Rootstown, OH 44272, USA
J Carcinog 8:9. 2009..d -Limonene could be used as a potent non-toxic agent to improve the treatment outcome of hormone-refractory prostate cancer with docetaxel...
Cancer prevention and treatment with resveratrol: from rodent studies to clinical trialsAnupam Bishayee
Department of Pharmaceutical Sciences, Northeastern Ohio Universities Colleges of Medicine and Pharmacy, 4209 State Route 44, Rootstown, OH 44272, USA
Cancer Prev Res (Phila) 2:409-18. 2009..The conclusion describes directions for future resveratrol research to establish its activity and utility as a human cancer preventive and therapeutic drug...
Resveratrol-mediated chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis: inhibition of cell proliferation and induction of apoptosisAnupam Bishayee
Department of Pharmaceutical Sciences, Northeastern Ohio Universities Colleges of Medicine and Pharmacy, 4209 State Route 44, Rootstown, OH 44272, USA
Chem Biol Interact 179:131-44. 2009..Due to a favorable toxicity profile, resveratrol can potentially be developed as a chemopreventive drug against human HCC...
Alteration of hepatic proinflammatory cytokines is involved in the resveratrol-mediated chemoprevention of chemically-induced hepatocarcinogenesisThomas Mbimba
Cancer Therapeutics and Chemoprevention Group, Department of Pharmaceutical Sciences, College of Pharmacy, Northeast Ohio Medical University, Rootstown, OH 44272, USA
Curr Pharm Biotechnol 13:229-34. 2012..From the current results in conjunction with our previous findings, it can be concluded that resveratrol-mediated chemoprevention of rat liver carcinogenesis is related to alteration of proinflammatory cytokines...
Selenium in the prevention and treatment of hepatocellular carcinomaAltaf S Darvesh
Cancer Therapeutics and Chemoprevention Emphasis Group, Department of Pharmaceutical Sciences, Northeastern Ohio Universities Colleges of Medicine and Pharmacy, Rootstown, OH 44272, USA
Anticancer Agents Med Chem 10:338-45. 2010..Future directions and potential challenges involved in the advance of selenium use in the prevention and treatment of liver cancer are also discussed...
Resveratrol in the chemoprevention and treatment of hepatocellular carcinomaAnupam Bishayee
Department of Pharmaceutical Sciences, Northeastern Ohio Universities Colleges of Medicine and Pharmacy, Rootstown, 44272, USA
Cancer Treat Rev 36:43-53. 2010..Future directions and challenges involved in the use of resveratrol for the prevention and treatment of HCC are also discussed...
Chemopreventive doses of resveratrol do not produce cardiotoxicity in a rodent model of hepatocellular carcinomaDaniel J Luther
Department of Integrative Medical Sciences, Northeastern Ohio Universities Colleges of Medicine and Pharmacy, Rootstown, OH 44272, USA
Invest New Drugs 29:380-91. 2011..Our results indicate that resveratrol-mediated chemoprevention of rat liver carcinogenesis is devoid of any adverse cardiovascular events. Resveratrol may be developed as a chemopreventive as well as therapeutic drug for human HCC...
Oxidative stress and Alzheimer's disease: dietary polyphenols as potential therapeutic agentsAltaf S Darvesh
Northeastern Ohio Universities Colleges of Medicine and Pharmacy, Rootstown, OH 44272, USA
Expert Rev Neurother 10:729-45. 2010..Finally, innovative concepts, novel hypotheses, current challenges and future directions in the use of dietary polyphenols for the treatment of AD are discussed...
Natural products of dietary origin as lead compounds in virtual screening and drug designWerner J Geldenhuys
Department of Pharmaceutical Sciences, Northeast Ohio Medical University, 4209 State Route 44, Rootstown, OH 44272, USA
Curr Pharm Biotechnol 13:117-24. 2012..Natural dietary constituents, such as resveratrol, curcumin and caffeine as well as other compounds, are discussed to illustrate this approach...
Terpenoids and breast cancer chemopreventionThangaiyan Rabi
Department of Pharmaceutical Sciences, Northeastern Ohio Universities Colleges of Medicine and Pharmacy, 4209 State Route 44, Rootstown, OH 44272, USA
Breast Cancer Res Treat 115:223-39. 2009..Future directions in the field of chemoprevention are proposed based on recently acquired mechanistic insights into breast carcinogenesis...
Brain-targeted delivery of Tempol-loaded nanoparticles for neurological disordersRichard T Carroll
Department of Pharmaceutical Sciences, Northeastern Ohio Universities Colleges of Medicine and Pharmacy, Rootstown, Ohio 44272, USA
J Drug Target 18:665-74. 2010..Our findings suggest that transferrin-conjugated NPs containing antioxidants may be useful in the treatment of neurodegenerative diseases...
Curcumin and liver cancer: a reviewAltaf S Darvesh
Cancer Therapeutics and Chemoprevention Group, Department of Pharmaceutical Sciences, College of Pharmacy, Northeast Ohio Medical University, Rootstown, OH 44272, USA
Curr Pharm Biotechnol 13:218-28. 2012..This review also discusses potential challenges involved in the use of curcumin in HCC, such as bioavailability, pharmacokinetics, drug delivery as well as paucity of clinical studies...
Terpenoids as potential chemopreventive and therapeutic agents in liver cancerRoslin J Thoppil
Roslin J Thoppil, Anupam Bishayee, Cancer Therapeutics and Chemoprevention Group, Department of Pharmaceutical Sciences, Northeastern Ohio Universities Colleges of Medicine and Pharmacy, Rootstown, OH 44272, United States
World J Hepatol 3:228-49. 2011..Potential challenges and future directions involved in the advancement of these promising natural compounds in the chemoprevention and therapy of human liver cancer are also discussed...
