Rena Feinman

Summary

Affiliation: New Jersey
Country: USA

Publications

  1. ncbi Regulation of NF-kB in multiple myeloma: therapeutic implications
    Rena Feinman
    Department of Surgery, UMDNJ New Jersey Medical School, 185 South Orange Avenue MSB G510, Newark, NJ 07103, USA
    Clin Adv Hematol Oncol 2:162-6. 2004
  2. ncbi Molecular signatures of trauma-hemorrhagic shock-induced lung injury: hemorrhage- and injury-associated genes
    Rena Feinman
    Department of Surgery, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, New Jersey 07103, USA
    Shock 28:360-8. 2007
  3. ncbi HIF-1 mediates pathogenic inflammatory responses to intestinal ischemia-reperfusion injury
    Rena Feinman
    UMDNJ New Jersey Medical School, Dept of Surgery, Newark, 07103, USA
    Am J Physiol Gastrointest Liver Physiol 299:G833-43. 2010
  4. ncbi Hypoxia-inducible factor plays a gut-injurious role in intestinal ischemia reperfusion injury
    Kolenkode B Kannan
    Dept of Surgery, UMDNJ New Jersey Medical School, Newark, 07103, USA
    Am J Physiol Gastrointest Liver Physiol 300:G853-61. 2011
  5. ncbi Estrogen receptor hormone agonists limit trauma hemorrhage shock-induced gut and lung injury in rats
    Danielle Doucet
    Department of Surgery, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, New Jersey, United States of America
    PLoS ONE 5:e9421. 2010
  6. ncbi Estrogenic hormone modulation abrogates changes in red blood cell deformability and neutrophil activation in trauma hemorrhagic shock
    Danielle R Doucet
    Department of Surgery, New Jersey Medical School, Newark, New Jersey 07103, USA
    J Trauma 68:35-41. 2010
  7. ncbi Mesenteric lymph duct ligation improves survival in a lethal shock model
    Chirag D Badami
    Department of Surgery, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey 07103, USA
    Shock 30:680-5. 2008
  8. ncbi Intravenous injection of trauma-hemorrhagic shock mesenteric lymph causes lung injury that is dependent upon activation of the inducible nitric oxide synthase pathway
    Maheswari Senthil
    Department of Surgery, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103, USA
    Ann Surg 246:822-30. 2007
  9. ncbi Trauma-hemorrhagic shock-induced pulmonary epithelial and endothelial cell injury utilizes different programmed cell death signaling pathways
    Dimtrios Barlos
    Department of Surgery, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, New Jersey 07103, USA
    Am J Physiol Lung Cell Mol Physiol 296:L404-17. 2009
  10. ncbi Anticoagulants influence the in vitro activity and composition of shock lymph but not its in vivo activity
    Edwin A Deitch
    Department of Surgery, UMDNJ New Jersey Medical School, Newark, NJ 07103, USA
    Shock 36:177-83. 2011

Collaborators

  • E A Deitch
  • Qi Lu
  • Gregg Semenza
  • George W Machiedo
  • James Berenson
  • C J Hauser
  • Da Zhong Xu
  • Iriana Colorado
  • Kolenkode B Kannan
  • Danielle Doucet
  • Billy Abungu
  • David Palange
  • Maheswari Senthil
  • Da-Zhong Xu
  • Hiroshi Homma
  • Diego C Reino
  • R Paul Bonitz
  • Danielle R Doucet
  • Vadim Pisarenko
  • Francis J Caputo
  • Dimtrios Barlos
  • Anthony Watkins
  • Chirag D Badami
  • Jadd Koury
  • Diego Reino
  • Robert P Bonitz
  • Benjamin Chandler
  • Sharvil U Sheth
  • Madhuri Ramanathan
  • Xiaofa Qin
  • Mahdury Ramanathan
  • Chirag Badami
  • Michael Condon
  • Eleanora Feketeova
  • Anthony C Watkins
  • Frank J Caputo
  • Bobby J Rupani
  • Frank Caputo
  • Dimitrios Barlos
  • Erik Hoy
  • Pranoti Gangurde
  • Michael R Condon

Detail Information

Publications14

  1. ncbi Regulation of NF-kB in multiple myeloma: therapeutic implications
    Rena Feinman
    Department of Surgery, UMDNJ New Jersey Medical School, 185 South Orange Avenue MSB G510, Newark, NJ 07103, USA
    Clin Adv Hematol Oncol 2:162-6. 2004
    ..This article highlights regulatory mechanisms responsible for constitutive NF-kappaB activation and provides justification for target-based therapy for NF-kappaB in multiple myeloma...
  2. ncbi Molecular signatures of trauma-hemorrhagic shock-induced lung injury: hemorrhage- and injury-associated genes
    Rena Feinman
    Department of Surgery, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, New Jersey 07103, USA
    Shock 28:360-8. 2007
    ..Our model system provided a unique opportunity to distinguish the molecular changes associated with T/HS-induced acute lung injury from the systemic molecular response to T/HS...
  3. ncbi HIF-1 mediates pathogenic inflammatory responses to intestinal ischemia-reperfusion injury
    Rena Feinman
    UMDNJ New Jersey Medical School, Dept of Surgery, Newark, 07103, USA
    Am J Physiol Gastrointest Liver Physiol 299:G833-43. 2010
    ..Consequently, these results provide unique information on the initiating events in trauma-hemorrhagic shock-induced ALI and MODS as well as potential therapeutic insights...
  4. ncbi Hypoxia-inducible factor plays a gut-injurious role in intestinal ischemia reperfusion injury
    Kolenkode B Kannan
    Dept of Surgery, UMDNJ New Jersey Medical School, Newark, 07103, USA
    Am J Physiol Gastrointest Liver Physiol 300:G853-61. 2011
    ..However, the duration and severity of the gut I/R insult dictate whether HIF-1 plays a gut-protective or deleterious role...
  5. ncbi Estrogen receptor hormone agonists limit trauma hemorrhage shock-induced gut and lung injury in rats
    Danielle Doucet
    Department of Surgery, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, New Jersey, United States of America
    PLoS ONE 5:e9421. 2010
    ....
  6. ncbi Estrogenic hormone modulation abrogates changes in red blood cell deformability and neutrophil activation in trauma hemorrhagic shock
    Danielle R Doucet
    Department of Surgery, New Jersey Medical School, Newark, New Jersey 07103, USA
    J Trauma 68:35-41. 2010
    ..Thus, we examined the relative role of estrogen receptor (ER)-alpha and -beta in this protective response...
  7. ncbi Mesenteric lymph duct ligation improves survival in a lethal shock model
    Chirag D Badami
    Department of Surgery, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey 07103, USA
    Shock 30:680-5. 2008
    ..Nonetheless, in conclusion, these studies support the hypothesis that factors carried in the mesenteric lymph significantly contribute to the development of irreversible shock after SAO...
  8. ncbi Intravenous injection of trauma-hemorrhagic shock mesenteric lymph causes lung injury that is dependent upon activation of the inducible nitric oxide synthase pathway
    Maheswari Senthil
    Department of Surgery, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103, USA
    Ann Surg 246:822-30. 2007
    ....
  9. ncbi Trauma-hemorrhagic shock-induced pulmonary epithelial and endothelial cell injury utilizes different programmed cell death signaling pathways
    Dimtrios Barlos
    Department of Surgery, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, New Jersey 07103, USA
    Am J Physiol Lung Cell Mol Physiol 296:L404-17. 2009
    ..Collectively, T/HS-induced pulmonary endothelial PCD occurs via an AIF-dependent caspase-independent pathway, whereas epithelial cells undergo apoptosis by a caspase-dependent pathway...
  10. ncbi Anticoagulants influence the in vitro activity and composition of shock lymph but not its in vivo activity
    Edwin A Deitch
    Department of Surgery, UMDNJ New Jersey Medical School, Newark, NJ 07103, USA
    Shock 36:177-83. 2011
    ....
  11. ncbi Trauma hemorrhagic shock-induced lung injury involves a gut-lymph-induced TLR4 pathway in mice
    Diego C Reino
    Department of Surgery, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, New Jersey, United States of America
    PLoS ONE 6:e14829. 2011
    ....
  12. ncbi The female intestine is more resistant than the male intestine to gut injury and inflammation when subjected to conditions associated with shock states
    Hiroshi Homma
    Department of Surgery, MSB G506, UMDNJ, New Jersey Medical School, 185 South Orange Ave, Newark, NJ 07103-2714, USA
    Am J Physiol Gastrointest Liver Physiol 288:G466-72. 2005
    ....
  13. ncbi Persistent HIF-1alpha activation in gut ischemia/reperfusion injury: potential role of bacteria and lipopolysaccharide
    Jadd Koury
    Department of Surgery, UMDNJ New Jersey Medical School, Newark, New Jersey 07103, USA
    Shock 22:270-7. 2004
    ..aeruginosa or lipopolysaccharide...
  14. ncbi Phenylbutyrate-induced apoptosis is associated with inactivation of NF-kappaB IN HT-29 colon cancer cells
    Rena Feinman
    Division of Surgical Oncology, UMDNJ-New Jersey Medical School, Newark 07103, USA
    Cancer Chemother Pharmacol 49:27-34. 2002
    ..CONCLUSION: These results suggest that PB-induced apoptosis may be partly regulated through the inactivation of NF-kappaB. PB, an oral butyrate analogue, may have therapeutic potential in colon cancer...