Research Topics
| Leonard BielorySummaryAffiliation: New Jersey Country: USA Publications
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Publications
Complementary and alternative interventions in asthma, allergy, and immunologyLeonard Bielory
Department of Medicine, Pediatrics, and Ophthalmology, Division of Allergy, Immunology, and Rheumatology, UMDNJ New Jersey Medical School, Newark, New Jersey 07103, USA
Ann Allergy Asthma Immunol 93:S45-54. 2004..To review which herbs are most commonly used as complementary and alternative medicine (CAM) for treatment of asthma, allergy, and immunologic conditions...
United States pharmacopeia development of the Medicare model formulary guidelinesLeonard Bielory
University of Medicine and Dentistry of New Jersey UMDNJ New Jersey Medical School, Newark, NJ 07081, USA
Am J Geriatr Cardiol 14:301-7. 2005....
Review of complementary and alternative medicine in treatment of ocular allergiesLeonard Bielory
Department of Medicine, UMDNJ New Jersey Medical School, Newark, New Jersey 07103, USA
Curr Opin Allergy Clin Immunol 3:395-9. 2003....
Ocular allergy. PrefaceLeonard Bielory
UMDNJ-New Jersey Medical School, 90 Bergen Street, DOC Suite 4700, Newark, NJ 07103, USA
Immunol Allergy Clin North Am 28:xi-xii. 2008
Stereoconfiguration of antiallergic and immunologic drugsLeonard Bielory
Division of Allergy, Immunology and Rheumatology, UMDNJ New Jersey Medical School, Newark, New Jersey 07103, USA
Ann Allergy Asthma Immunol 100:1-8; quiz 8-11, 36. 2008..To review the concept of chirality and its current role in the pharmacology of antiallergic, antiasthmatic, and immunologic agents...
Ocular allergy treatment comparisons: azelastine and olopatadineLeonard Bielory
Department of Medicine and Pediatric Ophthalmology, UMDNJ New Jersey Medical School, Newark, 07103, USA
Curr Allergy Asthma Rep 4:320-5. 2004..By studying the various target sites of drug action, an enhanced clinical response algorithm of these topical ocular agents can be implemented to maximize the response for patients suffering from ocular allergy...
Differential diagnoses of conjunctivitis for clinical allergist-immunologistsLeonard Bielory
Department of Medicine, UMDNJ New Jersey Medical School, Newark, New Jersey 07103, USA
Ann Allergy Asthma Immunol 98:105-14; quiz 114-7, 152. 2007..To provide a clinical overview of the types of conjunctivitis that are encountered by practicing clinical allergist-immunologists...
Vasomotor (perennial chronic) conjunctivitisLeonard Bielory
Clinical Research and Development, Division of Allergy, Immunology and Rheumatology, New Jersey Medical School, Newark, New Jersey 07103, USA
Curr Opin Allergy Clin Immunol 6:355-60. 2006..These conditions are not commonly included in the differential diagnosis of allergic conjunctivitis...
Ocular toxicity of systemic asthma and allergy treatmentsLeonard Bielory
Division of Allergy, Immunology and Rheumatology, UMDNJ New Jersey Medical School, 90 Bergen Street, DOC Suite 4700, Newark, NJ 07103, USA
Curr Allergy Asthma Rep 6:299-305. 2006..Clinicians should be aware that other systemic agents may complicate their attempts to maximize the treatment of ocular allergies...
Efficacy and tolerability of newer antihistamines in the treatment of allergic conjunctivitisLeonard Bielory
Department of Medicine, Pediatrics and Ophthalmology, Division of Allergy, Immunology and Rheumatology, UMDNJ New Jersey Medical School, Immuno Ophthalmology Service, 90 Bergen Street, DOC Suite 4700, Newark, NJ 07103, USA
Drugs 65:215-28. 2005..Lastly, topical corticosteroids may be considered for severe seasonal ocular allergy symptoms, although long-term use should be avoided because of risks of ocular adverse effects, including glaucoma and cataract formation...
Treating the ocular component of allergic rhinoconjunctivitis and related eye disordersLeonard Bielory
UMDNJ, New Jersey Medical School, Newark, New Jersey, USA
MedGenMed 9:35. 2007..However, this condition has not always been recognized, and earlier literature reported allergic conjunctivitis only within a subset of nasal allergy patients...
Histamine receptors and the conjunctivaLeonard Bielory
UMDNJ, New Jersey Medical School, Newark, New Jersey 07103, USA
Curr Opin Allergy Clin Immunol 5:437-40. 2005..The purpose of this review is to evaluate the effect of histamine on various receptors in the conjunctiva. A Medline search from 1980 was performed on the histamine receptor subtypes H1, H2 and H3 in the human conjunctiva...
Allergic diseases of the eyeLeonard Bielory
New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103, USA
Med Clin North Am 90:129-48. 2006..The emergence of new medications for the specific treatment of ocular symptoms over the course of the past 15 years offers a new field for improved patient care by the primary and sub-specialty health care providers...
Ocular allergy overviewLeonard Bielory
Division of Allergy, Immunology and Rheumatology, University of Medicine and Dentistry, New Jersey, New Jersey Medical School, 90 Bergen Street, DOC Suite 4700, Newark, NJ 07103, USA
Immunol Allergy Clin North Am 28:1-23, v. 2008..There are common features and some discerning features that, with a good history and examination, may provide a more focused and appropriate management...
Ocular allergy treatmentLeonard Bielory
UMDNJ New Jersey Medical School, 90 Bergen Street, DOC Suite 4700, Newark, NJ 07103, USA
Immunol Allergy Clin North Am 28:189-224, vii. 2008..Immunotherapy has been shown to decrease the sensitivity of the eye 10 to 100 fold and may have an effect for several years after halting of immunotherapy...
Ocular allergy guidelines: a practical treatment algorithmLeonard Bielory
UMDNJ, Asthma and Allergy Research Center, Immuno Ophthalmology Service, New Jersey Medical School, Newark, New Jersey, USA
Drugs 62:1611-34. 2002..Our advances in the basic understanding of these conditions are providing the foundation for guidelines that improve the ocular health of patients with ocular allergies...
Intranasal corticosteroids and the eye: from negative ocular effects to clinical efficacy as a class effectLeonard Bielory
Division of Allergy, Immunology, and Rheumatology, Departments of Medicine, UMDNJ-New Jersey Medical School, Newark, New Jersey 07103, USA
Ann Allergy Asthma Immunol 100:506-8. 2008
Update on ocular allergy treatmentLeonard Bielory
UMDNJ Asthma and Allergy Research Center, Department of Medicine, Pediatrics and Ophthalmology, New Jersey Medical School, Newark, New Jersey 07103, USA
Expert Opin Pharmacother 3:541-53. 2002..The increased interest in advancing ocular treatment will lead to the development of additional therapies, novel pharmacokinetic delivery systems and, thus, improved healthcare outcomes for patients with allergic conjunctivitis...
American Academy of Allergy, Asthma & Immunology--2008 Annual MeetingLeonard Bielory
Division of Allergy, Immunology and Rheumatology, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, NJ 07103, USA
IDrugs 11:309-11. 2008
Topical immunopharmacology of ocular allergiesLeonard Bielory
Department of Medicine, UMDNJ, Asthma and Allergy Research Center, New Jersey Medical School, Newark, New Jersey, USA
Curr Opin Allergy Clin Immunol 2:435-45. 2002..To review the histamine-1 receptor antagonists, mast cell blockers and natural agents with such actions that can be used for the topical treatment of ocular allergies...
Current opinion of immunotherapy for ocular allergyLeonard Bielory
Division of Allergy, Immunology, and Rheumatology, UMDNJ New Jersey Medical School, Newark, USA
Curr Opin Allergy Clin Immunol 2:447-52. 2002..However, the role of immunotherapy for primary treatment of allergic conjunctivitis is unclear. We reviewed the studies where immunotherapy was used with particular attention to the affects on ocular allergies...
Ocular symptom reduction in patients with seasonal allergic rhinitis treated with the intranasal corticosteroid mometasone furoateLeonard Bielory
Div Allergy, Immunology, and Rheumatology, Clinical Research and Development, Dept of Medicine, Pediatrics, and Ophthalmology, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, New Jersey 07103, USA
Ann Allergy Asthma Immunol 100:272-9. 2008..Extensive evidence supports the ability of intranasal corticosteroids to reduce nasal symptoms of AR, although less evidence is available to define clearly their impact on allergic conjunctivitis...
Intranasal corticosteroids: do they improve ocular allergy?Catherine Origlieri
Division of Allergy, Immunology and Rheumatology, UMDNJ, New Jersey Medical School, Springfield, NJ 07081, USA
Curr Allergy Asthma Rep 9:304-10. 2009..INS are thought to exert their influence on the eye through the naso-ocular reflex, and to date their impact on ocular symptoms appears to be a class effect...
Concerns about intranasal corticosteroids for over-the-counter use: position statement of the Joint Task Force for the American Academy of Allergy, Asthma and Immunology and the American College of Allergy, Asthma and ImmunologyLeonard Bielory
Department of Medicine, UMDNJ-New Jersey Medical School, Newark, USA
Ann Allergy Asthma Immunol 96:514-25. 2006..Thus, as stated, we recommend that intranasal corticosteroids remain prescription-only drugs...
Defining complementary and alternative medicine in allergies and asthma: benefits and risksJennifer Heimall
Division of Allergy, Immunology, and Rheumatology, UMDNJ-Asthma and Allergy Research Center, New Jersey Medical School, Newark, NJ 07103, USA
Clin Rev Allergy Immunol 27:93-103. 2004....
Late-phase reaction in ocular allergySoo Hyun Choi
UMDNJ, New Jersey Medical School, Newark, New Jersey, USA
Curr Opin Allergy Clin Immunol 8:438-44. 2008..To determine if the late-phase reaction, which commonly occurs in allergic rhinitis and asthma, is also found in ocular allergy...
Aeroallergen prevalence in the northern New Jersey-New York City metropolitan area: a 15-year summaryAva Port
Division of Allergy, Immunology, and Rheumatology, University of Medicine and Dentistry of New Jersey-New Jersey Medical School, Newark 07103, USA
Ann Allergy Asthma Immunol 96:687-91. 2006..The most pronounced drop has been in weed pollen levels. Grass pollen demonstrates a biphasic pattern. Tree pollen composes most annual pollen measured in the northern New Jersey-New York City area...
Allergic rhinoconjunctivitis: complementary treatments for the 21st centurySimi Kapoor
University of Medicine and Dentistry of New Jersey Asthma and Allergy Research Center, Newark, NJ 07103, USA
Curr Allergy Asthma Rep 9:121-7. 2009....
Complementary and alternative medicine: herbs, phytochemicals and vitamins and their immunologic effectsTimothy Mainardi
University of Medicine and Dentistry New Jersey New Jersey Medical School, Newark, NJ, USA
J Allergy Clin Immunol 123:283-94; quiz 295-6. 2009..This article reviews the history of CAM and its use among patients, paying special attention to new research focusing on herbals, phytochemicals, and vitamins and their potential interaction with the immune system...
Emerging drugs for conjunctivitisCatherine Origlieri
STARx Allergy and Asthma Center, UMDNJ New Jersey Medical School, 400 Mountain Avenue, Springfield, New Jersey, NJ 07081, USA
Expert Opin Emerg Drugs 14:523-36. 2009..Treatment requires frequent dosing and often lacks complete efficacy...
OralairĀ®: sublingual immunotherapy for the treatment of grass pollen allergic rhinoconjunctivitisJison Hong
UMDNJ New Jersey Medical School, 90 Bergen Street, Newark, NJ 07103, USA
Expert Rev Clin Immunol 7:437-44. 2011..Treatment is scheduled to start approximately 4 months before the actual start of the pollen season and should be continued throughout the season. The treatment should be prescribed and initiated by an experienced allergy specialist...
Intranasal corticosteroids and allergic rhinoconjunctivitisCatherine Origlieri
UMDNJ New Jersey Medical School, Newark, New Jersey 07103, USA
Curr Opin Allergy Clin Immunol 8:450-6. 2008..To describe recent insight into the efficacy of intranasal corticosteroids in treating ocular signs and symptoms of allergic rhinoconjunctivitis...
Clinical efficacy, mechanisms of action, and adverse effects of complementary and alternative medicine therapies for asthmaLeonard Bielory
Division of Allergy, Immunology and Rheumatology Departments of Medicine and Pediatrics, UMDNJ, New Jersey Medical School, 90 Bergen Street, DOC 4700, Newark, NJ 07081, USA
Allergy Asthma Proc 25:283-91. 2004..This paper focuses on clinical and laboratory research regarding various CAM therapies that have been used in the treatment of asthma. The references cited are confined to literature originally published or translated into English...
Allergic conjunctivitisLeonard Bielory
Division of Allergy, Immunology, and Rheumatology, UMDNJ New Jersey Medical School, 90 Bergen Street, DOC Suite 4700, Newark, NJ 07103, USA
Immunol Allergy Clin North Am 28:43-58, vi. 2008..The development of "modified" corticosteroids has been a boon to the treatment of ocular allergy because these drugs may reduce potential side effects without sacrificing potency...
Chirality in ocular agentsAndrey Leonov
UMDNJ New Jersey Medical School, Newark, NJ 07103, USA
Curr Opin Allergy Clin Immunol 7:418-23. 2007..Practitioners prescribing ocular agents may benefit from understanding the effects of chirality in their evaluation of old and new medications...
Diagnosis and management of adult onset Still's diseaseP Efthimiou
Department of Medicine, New Jersey Medical School, UMDNJ, Newark, NJ 07101, USA
Ann Rheum Dis 65:564-72. 2006..Adult onset Still's disease (AOSD) is a rare systemic inflammatory disorder of unknown aetiology that is responsible for a significant proportion of cases of fever of unknown origin and can also have serious musculoskeletal sequelae...
Clinical characteristics, diagnostic criteria and therapeutic outcomes in autoimmune optic neuropathyL Frohman
Department of Ophthalmology and Visual Sciences, UMDNJ New Jersey Medical School, Newark, NJ 07103, USA
Br J Ophthalmol 93:1660-6. 2009..It may improve with large doses of corticosteroids alone, or in combination with immunosuppressive agents. The aim was to determine the relative effectiveness of various therapeutic regimens in AON...
Allergy to ophthalmic preservativesJison Hong
UMDNJ New Jersey Medical School, Newark, USA
Curr Opin Allergy Clin Immunol 9:447-53. 2009..The purpose of the present review is to examine the hypersensitivity reactions to preservatives in topical ophthalmic therapies...
Complementary and alternative medicine herbal therapies for atopic disordersGary B Zuckerman
Departments of Medicine, Pediatrics, and Ophthalmology, University of Medicine and Dentistry of New Jersey-New Jersey Medical School, Newark, New Jersey 07103, USA
Am J Med 113:47S-51S. 2002....
Role of antihistamines in ocular allergyLeonard Bielory
Departments of Medicine, Pediatrics, and Ophthalmology, University of Medicine and Dentistry of New Jersey Asthma and Allergy Research Center, New Jersey Medical School, Newark, New Jersey 07103, USA
Am J Med 113:34S-7S. 2002....
The relation of stroke admissions to recent weather, airborne allergens, air pollution, seasons, upper respiratory infections, and asthma incidence, September 11, 2001, and day of the weekRonald B Low
Department of Surgery Emergency Medicine, University of Medicine and Dentistry of New Jersey, Newark, USA
Stroke 37:951-7. 2006..Alveolar inflammation was proposed as the mechanistic link. We present a unified model of time, weather, pollution, and upper respiratory infection (URI) incidence...
Ocular allergy and dry eye syndromeLeonard Bielory
University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, New Jersey 07081, USA
Curr Opin Allergy Clin Immunol 4:421-4. 2004..This review is timely and relevant due to the recent FDA approval of several new agents for the treatment of dry eye syndrome...
Risk of cataracts and glaucoma with inhaled steroid use in childrenSailaja Nootheti
University of Medicine and Dentistry of New Jersey, 90 Bergen Street, Newark, NJ 07103, USA
Compr Ophthalmol Update 7:31-9. 2006..The search focused on the effects of inhaled corticosteroids in both adults and children, but contained an emphasis on children; studies pertaining to the effects in children, however, are limited...
Complementary therapy in allergic rhinitisElena S Resnick
Division of Allergy, Immunology, and Rheumatology, UMDNJ New Jersey Medical School, Newark, NJ 07103, USA
Curr Allergy Asthma Rep 8:118-25. 2008..Researchers have yet to determine how to integrate these CAM modalities into the general treatment paradigm of allergic rhinitis...
Allergic. IntroductionLeonard Bielory
Departments of Medicine, Pediatrics, and Ophthalmology, University of Medicine and Dentistry of New Jersey-New Jersey Medical School, Asthma and Allergy Research Center, Newark, New Jersey 07103, USA
Am J Med 113:1S. 2002
Autoimmune optic neuropathy with anticardiolipin antibody mimicking multiple sclerosis in a childLarry Frohman
Department of Ophthalmology, University of Medicine and Dentistry New Jersey, New Jersey Medical School, Newark, New Jersey, USA
Am J Ophthalmol 136:358-60. 2003..To demonstrate that autoimmune optic neuropathy (AON) may occur in the pediatric population...
Allergic eye disordersLeonard Bielory
UMDNJ-New Jersey Medical School, Newark, New Jersey, USA
Clin Allergy Immunol 16:311-23. 2002
Efficacy of intranasal corticosteroids for the ocular symptoms of allergic rhinitis: A systematic reviewJison Hong
University of Medicine and Dentistry of New Jersey, Newark, USA
Allergy Asthma Proc 32:22-35. 2011..56 (95% CI, 7.66-9.46). To date, clinical studies conducted statistically showed the efficacy of INCS on the OS of AR as evidenced by the meta-analysis results for the studies reporting total OSs...
Dermatologic and allergic conditions of the eyelidBelle Peralejo
Department of Medicine, Division of Allergy, Immunology, and Rheumatology, UMDNJ New Jersey Medical School, 90 Bergen Street, Newark, NJ 07103, USA
Immunol Allergy Clin North Am 28:137-68, vii. 2008..Topics include various eyelid dermatitis, inflammatory lesions, infections, benign and malignant tumor, urticaria, vascular lesions, and others. Treatment considerations for these conditions of the eyelid are also discussed...
Meta-analysis of clinical trials of probiotics for prevention and treatment of pediatric atopic dermatitisJoohee Lee
University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, NJ 07103 2499, USA
J Allergy Clin Immunol 121:116-121.e11. 2008..Prenatal and postnatal probiotic supplementation for prevention and treatment of pediatric atopic dermatitis (PAD) has been studied in clinical trials, but results have been mixed and hindered by heterogeneity of study design...
Efficacy and tolerability of second- and third-generation antihistamines in the treatment of acquired cold urticaria: a meta-analysisMark E Weinstein
Division of Allergy, Immunology, and Rheumatology, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, NJ 07103, USA
Ann Allergy Asthma Immunol 104:518-22. 2010..Acquired cold urticaria (ACU) is a form of physical urticaria that has been treated with first-generation antihistamines; there is a paucity of data regarding second- and third-generation antihistamines for the treatment of ACU...
Sarcoidosis of the anterior visual pathway: 24 new casesLarry P Frohman
Institute of Ophthalmology and Visual Sciences, UMDNJ New Jersey Medical School, 90 Bergen Street, Newark, NJ 07103, USA
J Neuroophthalmol 23:190-7. 2003..To describe the clinical spectrum and a rational approach to the diagnosis of anterior visual pathway sarcoidosis...
Probiotics: a complementary approach in the treatment and prevention of pediatric atopic diseaseNeeta S Ogden
Department of Allergy, Immunology and Rheumatology, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, NJ 07081, USA
Curr Opin Allergy Clin Immunol 5:179-84. 2005..This article summarizes the research conducted over the past 10 years with a primary focus on the literature published since January 2003...
Dysgammaglobulinemia in steroid-dependent optic neuritis: response to gammaglobulin treatmentL P Frohman
Department of Ophthalmology, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark 07103 2714
J Clin Neuroophthalmol 11:241-5. 1991..Following steroid withdrawal and institution of gammaglobulin, the patient grew 6 inches within 2 years, regaining his vision, retrieving his stature, and normalizing his psychosocial development...
Evidence-based study design in ocular allergy trialsConstance H Katelaris
Department Immunology and Allergy, Clinical School, University of Western Sydney, Campbelltown, New South Wales, Australia
Curr Opin Allergy Clin Immunol 8:484-8. 2008....
Effects of glucocorticosteroids on the skin and eyeVincent S Beltrani
Department of Dermatology, Columbia University, 29 Fox Street, Poughkeepsie, NY 12601, USA
Immunol Allergy Clin North Am 25:557-80. 2005..All therapies are most effective when used for their specific diagnosis. This article attempts to provide an update on the geometrically progressing knowledge regarding the uses and misuses of GCSs for the eye and skin...
The science of complementary and alternative medicine: the plural of anecdote is not evidenceLeonard Bielory
Ann Allergy Asthma Immunol 93:S1-4. 2004
Alternative treatment for allergy and asthmaLeonard Bielory
Division of Allergy/Immunology, UMDNY-New Jersey Medical School, USA
J Asthma 40:47-53. 2003..One should remember, however, these treatments are made to complement most traditional therapies and not to replace them...
Mast cells and mast cell mediators as targets of dietary supplementsTheoharis C Theoharides
Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine and Tufts New England Medical Center, Boston, Massachusetts 02111, USA
Ann Allergy Asthma Immunol 93:S24-34. 2004..To review the increasing amount of data that support or dispel the use of dietary supplements in the treatment of inflammatory conditions that involve mast cells, such as allergies, arthritis, and chronic pelvic pain syndrome...
Intranasal corticosteroids reduce ocular symptoms of allergic rhinitis as a class effectLeonard Bielory
J Allergy Clin Immunol 121:538-9. 2008
Inhaled corticosteroids: past lessons and future issuesDavid B Allen
Division of Endocrinology, University of Wisconsin Children's Hospital, Madison 53792-4108, USA
J Allergy Clin Immunol 112:S1-40. 2003....
Beta2-agonists and paresthesias in multiple sclerosisSara Axelrod
Ann Allergy Asthma Immunol 98:100. 2007
Concepts in developing health-based indicators for ozoneClifford P Weisel
Environmental and Occupational Health Sciences Institute, 170 Frelinghuysen Road, Piscataway, NJ 08854, USA
Int Arch Occup Environ Health 75:415-22. 2002..g., changes in the prevalence of adverse health outcomes attributed to the pollutant. This manuscript presents the concepts of using asthma emergency room (ER) visits and hospital admission as potential health-based indicators for ozone...
Ocular cicatrical pemphigoidEric Kavosh
Allergy Asthma Proc 28:606-7. 2007
Vernal conjunctivitisJason Jun
Tufts University School of Medicine, Boston, MA, USA
Immunol Allergy Clin North Am 28:59-82, vi. 2008..Treatment of chronic forms of ocular allergies may necessitate collaborative efforts between the ophthalmologist and the allergist or immunologist...
Adverse reactions to complementary and alternative medicine: ragweed's cousin, the coneflower (echinacea), is "a problem more than a sneeze"Leonard Bielory
Ann Allergy Asthma Immunol 88:7-9. 2002
Replacing myth and prejudice with scientific facts about complementary and alternative medicineLeonard Bielory
Ann Allergy Asthma Immunol 88:249-50. 2002
Complementary and alternative medicine culturesLeonard Bielory
Ann Allergy Asthma Immunol 90:581-2. 2003
Contact lenses and associated anterior segment disorders: dry eye disease, blepharitis, and allergyMichael A Lemp
Georgetown University School of Medicine, 3900 Reservoir Road NW, Washington, DC 20007, USA
Immunol Allergy Clin North Am 28:105-17, vi-vii. 2008..In addition, a consideration of a careful strategy to identify patients with ocular allergy and manage the use of contact lenses in these patients is developed with an emphasis on the avoidance of complications...
