Larry H Smith

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi The value of parsing as feature generation for gene mention recognition
    Larry H Smith
    Computational Biology Branch, National Center for Biotechnology Information, Room 6S614 N, Building 38A, 8600 Rockville Pike, Bethesda, MD 20894, USA
    J Biomed Inform 42:895-904. 2009
  2. ncbi Overview of BioCreative II gene mention recognition
    Larry Smith
    National Center for Biotechnology Information, Bethesda, Maryland, USA
    Genome Biol 9:S2. 2008
  3. ncbi Retrieving definitional content for ontology development
    L Smith
    National Center for Biotechnology Information, NIH, NLM, Building 38A, 8600 Rockville Pike, Bethesda, MD 20894, USA
    Comput Biol Chem 28:387-91. 2004
  4. ncbi Hidden Markov models and optimized sequence alignments
    L Smith
    Computational Biology Branch, National Center for Biotechnology Information, National Library of Medicine, Rm 614D, Bldg 38A, 8600 Rockville Pike, Bethesda, MD 20894, USA
    Comput Biol Chem 27:77-84. 2003
  5. ncbi Identification of related gene/protein names based on an HMM of name variations
    L Yeganova
    Computational Biology Branch, National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bldg 38A, 8600 Rockville Pike, Bethesda, MD 20894, USA
    Comput Biol Chem 28:97-107. 2004
  6. ncbi MedPost: a part-of-speech tagger for bioMedical text
    L Smith
    Computational Biology Branch, National Center for Biotechnology Information
    Bioinformatics 20:2320-1. 2004
  7. ncbi Patient satisfaction with conventional and nurse-led telephone follow-up after nasal septal surgery
    S Uppal
    Department of Otolaryngology, Head and Neck Surgery, York Hospital, York, UK
    Int J Clin Pract 57:835-9. 2003
  8. ncbi Functional interaction between nucleosome assembly proteins and p300/CREB-binding protein family coactivators
    N Shikama
    Division of Biochemistry and Molecular Biology, University of Glasgow, Glasgow G12 8QQ, United Kingdom
    Mol Cell Biol 20:8933-43. 2000
  9. ncbi Mapping of the ARIX homeodomain gene to mouse chromosome 7 and human chromosome 11q13
    K R Johnson
    Department of Biochemistry and Molecular Biology, Oregon Health Sciences University, Portland, Oregon, 97201 3098, USA
    Genomics 33:527-31. 1996
  10. ncbi Synthesis and characterization of the Kunitz protease-inhibitor domain of the beta-amyloid precursor protein
    J Schilling
    California Biotechnology Inc, Mountain View 94043
    Gene 98:225-30. 1991

Collaborators

Detail Information

Publications10

  1. ncbi The value of parsing as feature generation for gene mention recognition
    Larry H Smith
    Computational Biology Branch, National Center for Biotechnology Information, Room 6S614 N, Building 38A, 8600 Rockville Pike, Bethesda, MD 20894, USA
    J Biomed Inform 42:895-904. 2009
    ..Features derived from parsers improved performance in this partial gene mention recognition task by a small but statistically significant amount. There were virtually no differences between parsers in these experiments...
  2. ncbi Overview of BioCreative II gene mention recognition
    Larry Smith
    National Center for Biotechnology Information, Bethesda, Maryland, USA
    Genome Biol 9:S2. 2008
    ..We also demonstrate that, by combining the results from all submissions, an F score of 0.9066 is feasible, and furthermore that the best result makes use of the lowest scoring submissions...
  3. ncbi Retrieving definitional content for ontology development
    L Smith
    National Center for Biotechnology Information, NIH, NLM, Building 38A, 8600 Rockville Pike, Bethesda, MD 20894, USA
    Comput Biol Chem 28:387-91. 2004
    ..The approach is evaluated automatically for terms with explicit definitions, and manually for terms with no available definition...
  4. ncbi Hidden Markov models and optimized sequence alignments
    L Smith
    Computational Biology Branch, National Center for Biotechnology Information, National Library of Medicine, Rm 614D, Bldg 38A, 8600 Rockville Pike, Bethesda, MD 20894, USA
    Comput Biol Chem 27:77-84. 2003
    ..The fully trainable model is applied to two problems in bioinformatics: the recognition of related gene/protein names and the alignment and scoring of homologous proteins...
  5. ncbi Identification of related gene/protein names based on an HMM of name variations
    L Yeganova
    Computational Biology Branch, National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bldg 38A, 8600 Rockville Pike, Bethesda, MD 20894, USA
    Comput Biol Chem 28:97-107. 2004
    ..The system is based on a dynamic programming algorithm for sequence alignment in which the mutation matrix is allowed to vary under the control of a fully trainable hidden Markov model...
  6. ncbi MedPost: a part-of-speech tagger for bioMedical text
    L Smith
    Computational Biology Branch, National Center for Biotechnology Information
    Bioinformatics 20:2320-1. 2004
    ..AVAILABILITY: Software, documentation and a corpus of 5700 manually tagged sentences are available at ftp://ftp.ncbi.nlm.nih.gov/pub/lsmith/MedPost/medpost.tar.gz..
  7. ncbi Patient satisfaction with conventional and nurse-led telephone follow-up after nasal septal surgery
    S Uppal
    Department of Otolaryngology, Head and Neck Surgery, York Hospital, York, UK
    Int J Clin Pract 57:835-9. 2003
    ..It makes more appointment slots available for patients with pressing clinical problems and has the potential to reduce outpatient access times in the NHS...
  8. ncbi Functional interaction between nucleosome assembly proteins and p300/CREB-binding protein family coactivators
    N Shikama
    Division of Biochemistry and Molecular Biology, University of Glasgow, Glasgow G12 8QQ, United Kingdom
    Mol Cell Biol 20:8933-43. 2000
    ..These results argue that NAP is a functionally important component of the p300 coactivator complex and suggest that NAP may serve as a point of integration between transcriptional coactivators and chromatin...
  9. ncbi Mapping of the ARIX homeodomain gene to mouse chromosome 7 and human chromosome 11q13
    K R Johnson
    Department of Biochemistry and Molecular Biology, Oregon Health Sciences University, Portland, Oregon, 97201 3098, USA
    Genomics 33:527-31. 1996
    ..3-q13.4. These map locations extend and further define regions of conserved synteny between mouse and human genomes and identify a new candidate gene for inherited developmental disorders linked to human 11q13...
  10. ncbi Synthesis and characterization of the Kunitz protease-inhibitor domain of the beta-amyloid precursor protein
    J Schilling
    California Biotechnology Inc, Mountain View 94043
    Gene 98:225-30. 1991
    ..Hence, this reKPI will be an important reagent in gaining a better understanding of the role of the KPI domain in beta-APP function and metabolism, as well as in the proteolytic events involved in beta-amyloid formation...