Wei Shao

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi RT-SHIV subpopulation dynamics in infected macaques during anti-HIV therapy
    Wei Shao
    Advanced Biomedical Computing Center, SAIC Frederick, Inc, National Cancer Institute at Frederick, Frederick, MD, USA
    Retrovirology 6:101. 2009
  2. ncbi Genetic diversity of simian immunodeficiency virus encoding HIV-1 reverse transcriptase persists in macaques despite antiretroviral therapy
    Mary Kearney
    HIV Drug Resistance Program, National Cancer Institute at Frederick, 1050 Boyles Street, Building 535, Room 109, Frederick, MD 21702 1201, USA
    J Virol 85:1067-76. 2011
  3. ncbi Frequent polymorphism at drug resistance sites in HIV-1 protease and reverse transcriptase
    Mary Kearney
    HIV Drug Resistance Program, National Cancer Institute, National Institutes of Health, Frederick, Maryland 21702 1201, USA
    AIDS 22:497-501. 2008
  4. ncbi Suppression of viremia and evolution of human immunodeficiency virus type 1 drug resistance in a macaque model for antiretroviral therapy
    Zandrea Ambrose
    HIV Drug Resistance Program, National Cancer Institute, Building 535, Room 123, Frederick, MD 21702, USA
    J Virol 81:12145-55. 2007
  5. ncbi Nature, position, and frequency of mutations made in a single cycle of HIV-1 replication
    Michael E Abram
    HIV Drug Resistance Program, National Cancer Institute at Frederick, Frederick, MD 21702 1201, USA
    J Virol 84:9864-78. 2010

Collaborators

Detail Information

Publications5

  1. ncbi RT-SHIV subpopulation dynamics in infected macaques during anti-HIV therapy
    Wei Shao
    Advanced Biomedical Computing Center, SAIC Frederick, Inc, National Cancer Institute at Frederick, Frederick, MD, USA
    Retrovirology 6:101. 2009
    ..Bioinformatics tools were constructed to trace individual genomes from the beginning of infection to the end of the treatment...
  2. ncbi Genetic diversity of simian immunodeficiency virus encoding HIV-1 reverse transcriptase persists in macaques despite antiretroviral therapy
    Mary Kearney
    HIV Drug Resistance Program, National Cancer Institute at Frederick, 1050 Boyles Street, Building 535, Room 109, Frederick, MD 21702 1201, USA
    J Virol 85:1067-76. 2011
    ....
  3. ncbi Frequent polymorphism at drug resistance sites in HIV-1 protease and reverse transcriptase
    Mary Kearney
    HIV Drug Resistance Program, National Cancer Institute, National Institutes of Health, Frederick, Maryland 21702 1201, USA
    AIDS 22:497-501. 2008
    ..Failure of antiretroviral therapy may result from the selection of pre-existing, drug-resistant HIV-1 variants, but the frequency and type of such variants have not been defined...
  4. ncbi Suppression of viremia and evolution of human immunodeficiency virus type 1 drug resistance in a macaque model for antiretroviral therapy
    Zandrea Ambrose
    HIV Drug Resistance Program, National Cancer Institute, Building 535, Room 123, Frederick, MD 21702, USA
    J Virol 81:12145-55. 2007
    ..By contrast, ART effectively suppressed RT-SHIV in 5/6 animals. These data indicate that suboptimal therapy facilitates HIV-1 drug resistance and suggest that this model can be used to investigate persisting viral reservoirs...
  5. ncbi Nature, position, and frequency of mutations made in a single cycle of HIV-1 replication
    Michael E Abram
    HIV Drug Resistance Program, National Cancer Institute at Frederick, Frederick, MD 21702 1201, USA
    J Virol 84:9864-78. 2010
    ..The pattern of hot spots seen in lacZalpha in vivo did not match any of the published data obtained when purified RT was used to copy lacZalpha in vitro...