Research Topics
Species | Sharon A RossSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Allyl sulfur compounds from garlic modulate aberrant crypt formationSharon A Ross
Nutritional Sciences Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, U S Department of Health and Human Services, Rockville, MD 20892 7328, USA
J Nutr 136:852S-854S. 2006..The response to these allyl sulfur compounds appears to depend on several factors, including the speciation, quantity, and duration provided...
Epigenetic modulation and cancer: effect of metabolic syndrome?Sharon A Ross
Nutritional Science Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 7328, USA
Am J Clin Nutr 86:s872-7. 2007..Thus, epigenetics may bridge both the thrifty genotype and thrifty phenotype hypotheses and provide a link between genes and the environment concerning disease predisposition to metabolic syndrome and its associated diseases...
MicroRNA, Nutrition, and Cancer PreventionSharon A Ross
Nutritional Science Research Group, National Cancer Institute, Bethesda, MD
Adv Nutr 2:472-85. 2011..Understanding the affect of dietary factors on miRNA expression and function may provide insight on prevention strategies to reduce the burden of cancer...
Nutritional genomic approaches to cancer prevention researchS A Ross
Nutritional Science Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
Exp Oncol 29:250-6. 2007..Recognition of the interplay between genes and diet could ultimately help identify modifiable molecular targets for preventing, delaying, or reducing the symptoms of cancer and other chronic diseases...
Evidence for the relationship between diet and cancerS A Ross
Nutritional Science Research Group, Division of Cancer Prevention, National Cancer Institute, EPN 3157, National Institutes of Health, Department of Health and Human Services, 6130 Executive Blvd, MSC 7328 Bethesda, MD 20892 7328, USA
Exp Oncol 32:137-42. 2010....
Dietary components impact histone modifications and cancer riskCindy D Davis
Nutritional Science Research Group, Division of Cancer Prevention, National Cancer Institute, 6130 Executive Boulevard, Suite 3159, Rockville, MD 20892 7328, USA
Nutr Rev 65:88-94. 2007..This review focuses on several histone-modifying enzymes that are associated with cancer development and their modification by bioactive food components...
Evidence for dietary regulation of microRNA expression in cancer cellsCindy D Davis
Nutritional Science Research Group, National Cancer Institute, 6130 Executive Blvd, Suite 3160, Rockville, MD 20892 7328, USA
Nutr Rev 66:477-82. 2008..miRNAs may be useful as biomarkers of cancer prevention or nutritional status, as well as serve as potential molecular targets that are influenced by dietary interventions...
New technologies for nutrition researchSharon A Ross
Nutritional Science Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
J Nutr 134:681-5. 2004..Highlights from this symposium are presented briefly herein...
Diet and DNA methylation interactions in cancer preventionSharon A Ross
Nutritional Science Research Group, Division of Cancer Prevention, National Cancer Institute, Bethesda, Maryland 20892, USA
Ann N Y Acad Sci 983:197-207. 2003..A third plausible mechanism may relate to DNA demethylation activity. Finally, the DNA methylation patterns may influence the response to a bioactive food component...
Nutritional links to plausible mechanisms underlying pancreatic cancer: a conference reportR Jean Hine
Nutritional Sciences Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892-7328, USA
Pancreas 27:356-66. 2003..The recommendations section suggests gaps in current knowledge and articulates future directions for this area of investigation...
Histone H3 lysine 9 and H4 lysine 20 trimethylation and the expression of Suv4-20h2 and Suv-39h1 histone methyltransferases in hepatocarcinogenesis induced by methyl deficiency in ratsIgor P Pogribny
National Center for Toxicological Research, Jefferson, AR 72078, National Cancer Institute, Bethesda, MD 20892 and University of Tennessee, Knoxville, TN 37996, USA
Carcinogenesis 27:1180-6. 2006....
Proceedings of the Trans-HHS Workshop: diet, DNA methylation processes and healthSharon A Ross
Nutritional Science Research Group, Division of Cancer Prevention, National Cancer Institute, Bethesda, MD 20892, USA
J Nutr 132:2329S-2332S. 2002
Nanotechnology research: applications in nutritional sciencesPothur R Srinivas
Atherothrombosis and Coronary Artery Diseases Branch, Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, Bethesda, MD 20892, USA
J Nutr 140:119-24. 2010..These efforts could facilitate exploration of previously inaccessible cellular compartments and intracellular pathways and thus uncover strategies for new prevention and therapeutic modalities...
Effect of long-term tamoxifen exposure on genotoxic and epigenetic changes in rat liver: implications for tamoxifen-induced hepatocarcinogenesisVolodymyr P Tryndyak
Division of Biochemical Toxicology, National Center for Toxicological Research, Jefferson, AR 72079, USA
Carcinogenesis 27:1713-20. 2006..These data indicate the importance of genotoxic and epigenetic alterations in the etiology of tamoxifen-induced hepatocarcinogenesis...
Dietary selenium affects homocysteine metabolism differently in Fisher-344 rats and CD-1 miceEric O Uthus
USDA, ARS, Grand Forks Human Nutrition Research Center, Grand Forks, ND 58202, USA
J Nutr 137:1132-6. 2007....
Gene expression profiling reveals underlying molecular mechanisms of the early stages of tamoxifen-induced rat hepatocarcinogenesisIgor P Pogribny
Division of Biochemical Toxicology, National Center for Toxicological Research, Jefferson, AR 72079, USA
Toxicol Appl Pharmacol 225:61-9. 2007..The early appearance of these alterations suggests their importance in the mechanism of neoplastic cell transformation induced by tamoxifen...
Methyl deficiency, alterations in global histone modifications, and carcinogenesisIgor P Pogribny
National Center for Toxicological Research, Jefferson, AR 72079, USA
J Nutr 137:216S-222S. 2007..These results illustrate the complexity and importance of histone modification changes in the etiology of hepatocarcinogenesis induced by MDD...
Differential effects of dietary selenium (se) and folate on methyl metabolism in liver and colon of ratsEric O Uthus
USDA ARS Grand Forks Human Nutrition Research Center, P O Box 9034, Grand Forks, ND 58202 9034, USA
Biol Trace Elem Res 109:201-14. 2006..This suggests that selenium deficiency appears to be a more important modifier of methyl metabolism than either adequate or supplemental selenium...
Irreversible global DNA hypomethylation as a key step in hepatocarcinogenesis induced by dietary methyl deficiencyIgor P Pogribny
Division of Biochemical Toxicology, National Center for Toxicological Research, 3900 NCTR Dr, Jefferson, AR 72079, USA
Mutat Res 593:80-7. 2006..These results provide an experimental evidence and a mechanistic basis by which epigenetic alterations may contribute to the initiation and promotion steps of carcinogenesis...
Epigenetic reprogramming of liver cells in tamoxifen-induced rat hepatocarcinogenesisVolodymyr P Tryndyak
Division of Biochemical Toxicology, National Center for Toxicological Research, Jefferson, AR 72079, USA
Mol Carcinog 46:187-97. 2007....
