Research Topics
Genomes and Genes
Species | Preetha RajaramanSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Occupation and risk of meningioma and acoustic neuroma in the United StatesPreetha Rajaraman
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892 7238, USA
Am J Ind Med 45:395-407. 2004..Workplace exposures may be related to the development of brain tumors. In this case-control study, we examine occupation as a risk factor for meningioma and acoustic neuroma...- Common variation in genes related to innate immunity and risk of adult gliomaPreetha Rajaraman
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA
Cancer Epidemiol Biomarkers Prev 18:1651-8. 2009..We have identified a promising set of innate immunity-related genetic regions for further investigation... - Nucleotide excision repair polymorphisms may modify ionizing radiation-related breast cancer risk in US radiologic technologistsPreetha Rajaraman
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892, USA
Int J Cancer 123:2713-6. 2008..1-21.3; EOR/Gy(AC/CC) = 0.6, 95% CI = <0, 4.6; p(het) = 0.01). These results suggest that common variants in nucleotide excision repair genes may modify the association between occupational radiation exposure and breast cancer risk... - Oxidative response gene polymorphisms and risk of adult brain tumorsPreetha Rajaraman
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 7238, USA
Neuro Oncol 10:709-15. 2008..6; 95% CI, 0.3-1.0). These relationships persisted when major groups of disease controls were excluded from the analysis. Our results suggest that common variants in the SOD2, SOD3, and CAT genes may influence brain tumor risk... - DNA repair gene polymorphisms and risk of adult meningioma, glioma, and acoustic neuromaPreetha Rajaraman
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, Bethesda, MD 20892 7238, USA
Neuro Oncol 12:37-48. 2010..03). Decreased glioma risk was observed with the XRCC1 rs1799782 variant (P(trend) .04). Our results suggest that common DNA repair variants may affect the risk of adult brain tumors, especially meningioma... - Risk of meningioma and common variation in genes related to innate immunityPreetha Rajaraman
Division of Cancer Epidemiology and Genetics, Neuro Oncology Branch, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Boulevard, EPS Room 7058, Bethesda, MD 20892 7238, USA
Cancer Epidemiol Biomarkers Prev 19:1356-61. 2010..The etiology of meningioma, the second most common type of adult brain tumor in the United States, is largely unknown. Prior studies indicate that history of immune-related conditions may affect the risk of meningioma... - Early life exposure to diagnostic radiation and ultrasound scans and risk of childhood cancer: case-control studyPreetha Rajaraman
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892 7238, USA
BMJ 342:d472. 2011..To examine childhood cancer risks associated with exposure to diagnostic radiation and ultrasound scans in utero and in early infancy (age 0-100 days)... - Polymorphisms in apoptosis and cell cycle control genes and risk of brain tumors in adultsPreetha Rajaraman
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, EPS Room 7085, 6120 Executive Boulevard, Bethesda, MD 20892 7238, USA
Cancer Epidemiol Biomarkers Prev 16:1655-61. 2007..Our results suggest that common variants in the CASP8, CCND1, CCNH, and MDM2 genes may influence brain tumor risk. Future research in this area should include more detailed coverage of genes in the apoptosis/cell cycle control pathways... - Lead, genetic susceptibility, and risk of adult brain tumorsPreetha Rajaraman
Division of Cancer Epidemiology Branch, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Boulevard, EPS Room 7085, Bethesda, MD 20892 7238, USA
Cancer Epidemiol Biomarkers Prev 15:2514-20. 2006..The ALAD G177C polymorphism affects the toxicokinetics of lead and may confer genetic susceptibility to adverse effects of lead exposure... - Hunting for the causes of meningioma--obesity is a suspectPreetha Rajaraman
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, NCI, Rockville, MD 20852, USA
Cancer Prev Res (Phila) 4:1353-5. 2011.... - Lung cancer risk among US radiologic technologists, 1983-1998Preetha Rajaraman
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, NCI, NIH, DHHS, Bethesda, MD 20892 7238, USA
Int J Cancer 119:2481-6. 2006..Overall, we find very limited evidence that chronic low-to-moderate dose occupational exposure increased lung cancer risk in the US Radiologic Technologist cohort... - Delta-aminolevulinic acid dehydratase polymorphism and risk of brain tumors in adultsPreetha Rajaraman
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Environ Health Perspect 113:1209-11. 2005..2; 95% CI, 0.7-2.2). No increased risk associated with the ALAD2 variant was observed for glioma or acoustic neuroma. These findings suggest that the ALAD2 allele may increase genetic susceptibility to meningioma... - Polymorphisms in estrogen biosynthesis and metabolism-related genes, ionizing radiation exposure, and risk of breast cancer among US radiologic technologistsAlice J Sigurdson
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Boulevard, EPS 7060, MSC 7238, Bethesda, MD, 20892 7238, USA
Breast Cancer Res Treat 118:177-84. 2009..06). We found suggestive evidence that common variants in selected estrogen metabolizing genes may modify the association between ionizing radiation exposure and breast cancer risk... - Lead exposure, polymorphisms in genes related to oxidative stress, and risk of adult brain tumorsParveen Bhatti
Department of Health ad Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland, USA
Cancer Epidemiol Biomarkers Prev 18:1841-8. 2009..Although the results of this study provide some evidence that lead may cause glioblastoma multiforme and meningioma through mechanisms related to oxidative damage, the results must be confirmed in other populations... - Polymorphisms in apoptosis- and proliferation-related genes, ionizing radiation exposure, and risk of breast cancer among U.S. Radiologic TechnologistsAlice J Sigurdson
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Boulevard, EPS 7092, MSC 7238, Bethesda, MD 20892 7238, USA
Cancer Epidemiol Biomarkers Prev 16:2000-7. 2007..For this reason, potential modification of the relationship between ionizing radiation exposure and breast cancer risk by polymorphic apoptosis gene variants have not been investigated among radiation-exposed women... - Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, ChinaMin Shen
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, MSC 7240, 6120 Executive Blvd, Bethesda, Maryland 20892 7240, USA
Environ Mol Mutagen 50:285-90. 2009..Integrin/receptor and complement pathways as well as IgE regulation are particularly noteworthy... - The mortality risk of smoking and obesity combinedD Michal Freedman
National Cancer Institute, Division of Epidemiology and Genetics, Bethesda, Maryland 20892, USA
Am J Prev Med 31:355-62. 2006..This nationwide, prospective mortality study of U.S. radiologic technologists was designed to evaluate the combined mortality risks of obesity and smoking... - Occupational exposure to pesticides and risk of adult brain tumorsClaudine M Samanic
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20852, USA
Am J Epidemiol 167:976-85. 2008..01). There was no association between meningioma and herbicide or insecticide exposure among men. These findings highlight the need to go beyond job title to elucidate potential carcinogenic exposures within different occupations... - Nonsteroidal anti-inflammatory drugs and glioma in the NIH-AARP Diet and Health Study cohortSarah E Daugherty
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland, USA
Cancer Prev Res (Phila) 4:2027-34. 2011..90; 95% CI, 0.65-1.25 and HR for glioblastoma = 0.83; 95% CI, 0.56-1.20) as compared with no use. Our findings from this large prospective study do not support an inverse association between NSAIDs and risk of all glioma or glioblastoma... - Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathwayH Dean Hosgood
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Carcinogenesis 29:1938-43. 2008..These results should be viewed as exploratory until they are replicated in a larger study... - Children's exposure to diagnostic medical radiation and cancer risk: epidemiologic and dosimetric considerationsMartha S Linet
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7238, USA
Pediatr Radiol 39:S4-26. 2009.... - Use of nonsteroidal anti-inflammatory drugs and risk of basal cell carcinoma in the United States radiologic technologists studyElizabeth K Cahoon
Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD
Int J Cancer 130:2939-48. 2012..In this large nationwide study, we observed no association between NSAID use and subsequent BCC risk... - The impact of delayed blood centrifuging, choice of collection tube, and type of assay on 25-hydroxyvitamin D concentrationsChu Ling Yu
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, 6120 Executive Boulevard, Mailstop 7238, Rockville, MD 20852, USA
Cancer Causes Control 21:643-8. 2010..01), but the difference was significant only after substantial centrifuging delays (96 h). Our study suggests no necessity for requiring immediate processing of blood samples after collection or for the choice of a tube type or assay... - Height, body mass index, and physical activity in relation to glioma riskSteven C Moore
Nutritional Epidemiology Branch and Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, NIH, Rockville, Maryland, USA
Cancer Res 69:8349-55. 2009..Adult height, BMI during adolescence, and physical activity during adolescence were each associated with glioma risk, supporting a role for early-life energy balance in glioma carcinogenesis... - Blood lead levels, ALAD gene polymorphisms, and mortalityDana M Van Bemmel
Cancer Prevention Fellowship Program, National Cancer Institute, Rockville, MD 20852, USA
Epidemiology 22:273-8. 2011..We examined whether the ALAD G177C single nucleotide polymorphism (SNP) affects the relationship between lead and mortality... - Common genetic variants in sex hormone pathway genes and papillary thyroid cancer riskSara J Schonfeld
1 Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland
Thyroid 22:151-6. 2012..This observation is in accord with the lack of consistent associations between hormonal factors and PTC risk in epidemiologic studies... - Sunlight, hormone replacement status and colorectal cancer risk in postmenopausal womenD Michal Freedman
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892 7238, USA
Int J Cancer 126:1997-2001. 2010.... - Brain tumor epidemiology: consensus from the Brain Tumor Epidemiology ConsortiumMelissa L Bondy
Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Cancer 113:1953-68. 2008..In this report, BTEC epidemiologists reviewed the group's consensus on the current state of scientific findings, and they present a consensus on research priorities to identify which important areas the science should move to address...