Research Topics
| W B PickworthSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
The effect of filter vent blocking and smoking topography on carbon monoxide levels in smokersAndrew A Strasser
Transdisciplinary Tobacco Use Research Center, Department of Psychiatry, University of Pennsylvania, 3535 Market Street, Philadelphia, PA 19104, USA
Pharmacol Biochem Behav 82:320-9. 2005..When participants do not switch brands within a session, smoking topography measures are predictive of CO boost...- EEG effects of conventional and denicotinized cigarettes in a spaced smoking paradigmWallace B Pickworth
NIDA, Intramural Research Program, 5500 Nathan Shock Drive, P O Box 5180, Baltimore, MD 21224, USA
Brain Cogn 53:75-81. 2003..The results indicate that nicotine delivery, recentness and the process of smoking importantly influence the EEG; other, non-nicotine components of tobacco smoke may also exert EEG effects... - A laboratory study of hydromorphone and cyclazocine on smoking behavior in residential polydrug usersWallace B Pickworth
National Institute on Drug Abuse NIDA, Intramural Research Program, Clinical Pharmacology and Therapeutics Branch, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
Pharmacol Biochem Behav 77:711-5. 2004..4 mg) reduced exhaled carbon monoxide (CO) boost, a measure of smoke exposure. Further studies of the effects of kappa opioid agonists on smoking behavior may lead to a better understanding of the role of opiates in smoking behavior... - Sensory and physiologic effects of menthol and non-menthol cigarettes with differing nicotine deliveryWallace B Pickworth
Clinical Pharmacology Branch, National Institute on Drug Abuse, Intramural Research Program, Addiction Research Center, National Institutes of Health, PO Box 5180, Baltimore, MD 21224, USA
Pharmacol Biochem Behav 71:55-61. 2002..These results illustrate the importance of threshold levels of nicotine on subjective responses to cigarette smoking... - Pharmacodynamic effects of new de-nicotinized cigarettesW B Pickworth
Division of Intramural Research, Addiction Research Center, Baltimore, Maryland 21224, USA
Nicotine Tob Res 1:357-64. 1999..The de-nicotinized cigarettes may prove useful in evaluating effects of smoking independent of the delivery of nicotine... - Effects of abused drugs on psychomotor performanceW B Pickworth
Intramural Research Program, National Institute on Drug Abuse, Baltimore, Maryland 21224, USA
Exp Clin Psychopharmacol 5:235-41. 1997..Results illustrate differences among drugs in producing performance impairment at doses that cause subjective effects. Increasing cognitive requirements uncovered performance impairment at lower doses... - Pharmacokinetics and pharmacodynamics of moist snuff in humansR V Fant
National Institute on Drug Abuse, Division of Intramural Research, Baltimore, Maryland, USA
Tob Control 8:387-92. 1999..The subjects remained in the experimental laboratory for an additional 60 minutes... - Endocrine effects of nicotine administration, tobacco and other drug withdrawal in humansW B Pickworth
National Institute on Drug Abuse, Addiction Research Center, Baltimore, MD 21224, USA
Psychoneuroendocrinology 23:131-41. 1998..The results indicated tobacco cessation caused small and transient effects on plasma hormone levels which were not significantly influenced by nicotine replacement and were not related to other signs of withdrawal... - Inhibition of prostaglandin synthesis and effects of ethanol and pentobarbital in humansW B Pickworth
National Institute on Drug Abuse, Intramural Research Program, Addiction Research Center, Baltimore, Maryland 21224, USA
J Pharmacol Exp Ther 283:274-80. 1997.... - Cyclazocine: comparison to hydromorphone and interaction with cocaineK L Preston
National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Department of Health and Human Services, Baltimore, Maryland 21224, USA
Behav Pharmacol 15:91-102. 2004..This study is suggestive but not strongly supportive for the use of kappa-opiate drugs to diminish acute effects of cocaine administration or for the use of these kappa agonists in drug abuse treatment applications... - Pupillometry in the detection of concomitant drug use in opioid-maintained patientsR Murillo
National Institute on Drug Abuse, Intramural Research Program, Baltimore, Maryland 21224, USA
Methods Find Exp Clin Pharmacol 26:271-5. 2004..These preliminary results suggest that pupillometry may be useful to verify concomitant drug use in a methadone-maintained population. Successful implementation of the methodology could reduce costly and intrusive urine testing... - Comparison of the nicotine content of tobacco used in bidis and conventional cigarettesJ L Malson
National Institute on Drug Abuse, Intramural Research Program, Baltimore, Maryland, USA
Tob Control 10:181-3. 2001..Therefore, it is logical to presume that bidi smokers are at risk of becoming nicotine dependent. These findings belief a popular belief among US teens that bidis are a safe alternative to commercial cigarettes... - Clove cigarette smoking: biochemical, physiological, and subjective effectsJennifer L Malson
National Institute on Drug Abuse, Intramural Research Program, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
Pharmacol Biochem Behav 74:739-45. 2003..Taste satisfaction, aromatic odor, and novelty may contribute to their appeal to young smokers... - Reliability and validity of a Short Form of the Tobacco Craving QuestionnaireStephen J Heishman
Nicotine Psychopharmacology Unit, Clinical Pharmacology and Therapeutics Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224, USA
Nicotine Tob Res 10:643-51. 2008..Test-retest correlation coefficients were also similar to those found in a previous study. These findings suggest that the TCQ-SF is as valid and reliable as the 47-item TCQ in measuring tobacco craving... - Smoking topography predicts abstinence following treatment with nicotine replacement therapyAndrew A Strasser
Transdisciplinary Tobacco Use Research Center, University of Pennsylvania, 3535 Market Street, Suite 4100, Philadelphia, PA 19104 3309, USA
Cancer Epidemiol Biomarkers Prev 13:1800-4. 2004..A secondary objective was to determine the relationship of smoking topography to carbon monoxide (CO) exposure... - Effects of different nicotine replacement therapies on postcessation psychological responsesAndrew A Strasser
Tobacco Use Research Center, Department of Psychiatry, University of Pennsylvania, 3535 Market Street, Suite 4100, Philadelphia, PA 19140 3309, USA
Addict Behav 30:9-17. 2005..These findings indicate that, although TN may enhance positive affect for smokers in treatment compared with NS, only changes in negative affect predict treatment outcome... - Safety and efficacy of the nicotine patch and gum for the treatment of adolescent tobacco addictionEric T Moolchan
Teen Tobacco Addiction Research Clinic, Clinical Pharmacology and Therapeutics Research Branch, National Institute on Drug Abuse, Intramural Research Program, 5500 Nathan Shock Dr, Baltimore, Maryland 21224, USA
Pediatrics 115:e407-14. 2005..To determine the safety and efficacy of the nicotine patch and gum for adolescents who want to quit smoking... - Placebo cigarettes in a spaced smoking paradigmNicole C Eid
National Institute on Drug Abuse, Intramural Research Program, Baltimore, MD, USA
Pharmacol Biochem Behav 81:158-64. 2005..However, the nicotine yield of the cigarette did not influence these patterns. It is concluded that acute tobacco cravings can be repeatedly diminished with cigarettes that do not deliver nicotine... - Smoking rates and topography predict adolescent smoking cessation following treatment with nicotine replacement therapyFrederick H Franken
Department of Health and Human Services, National Institute on Drug Abuse, Intramural Research Program, Baltimore, MD 21224, USA
Cancer Epidemiol Biomarkers Prev 15:154-7. 2006..If confirmed in a larger sample, our findings suggest that puff topography, and possibly CPD, might predict cessation outcome better than Fagerström scores in adolescent smokers... - Gender differences in acute tobacco withdrawal: effects on subjective, cognitive, and physiological measuresAdam M Leventhal
Department of Behavioral Science, University of Texas M D Anderson Cancer Center, TX, USA
Exp Clin Psychopharmacol 15:21-36. 2007..10). These findings suggest that there are qualitative gender differences in the acute tobacco withdrawal syndrome that may underlie gender-specific smoking patterns... - Predictors of smoking development in a population-based sample of adolescents: a prospective studyMarianne B M van den Bree
University of Wales, College of Medicine, Division of Psychological Medicine, Heath Park, Cardiff CF14 4XN, Wales, United Kingdom
J Adolesc Health 35:172-81. 2004..CONCLUSIONS: These findings may direct efforts for prevention and intervention of adolescent smoking behavior and may also provide guidance for future studies... - Nicotine delivery from smoking bidis and an additive-free cigaretteJennifer L Malson
Intramural Research Program, National Institute on Drug Abuse, Baltimore, Maryland 21224, USA
Nicotine Tob Res 4:485-90. 2002..These results do not support an emerging belief that bidi cigarettes are safer than conventional brands... - Bidis--hand-rolled, Indian cigarettes: effects on physiological, biochemical and subjective measuresJennifer L Malson
The College of Notre Dame of Maryland, Baltimore, MD, USA
Pharmacol Biochem Behav 72:443-7. 2002..Our results do not support the belief that bidis are a safe alternative to conventional cigarettes. Furthermore, bidi smoking, like conventional cigarette smoking, may lead to nicotine dependence... - Olanzapine attenuates cue-elicited craving for tobaccoKent E Hutchison
Department of Psychology, University of Colorado, Campus Box 345, Boulder, CO, 80309 0345, USA
Psychopharmacology (Berl) 175:407-13. 2004..Imaging, and pharmacological studies have supported a role for dopaminergic structures in cue-elicited craving for tobacco... - Quantitative comparisons between a nicotine delivery device (Eclipse) and conventional cigarette smokingEun M Lee
National Institute on Drug Abuse, Intramural Research Program, Baltimore, MD, USA
Nicotine Tob Res 6:95-102. 2004..The findings further validate the use of a topography device as an effective instrument to quantify smoke exposure... - Eclipse can deliver crack cocaineStacey L Steckley
Nicotine Tob Res 4:S189-90. 2002 - Smoking topography: reliability and validity in dependent smokersEun M Lee
National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Baltimore MD 21224, USA
Nicotine Tob Res 5:673-9. 2003..Overall, the data from these two small-sample studies suggest that smoking topography provides a valid and reliable index of conventional smoking and an indirect measure of smoke exposure... - Associations between Cloninger's temperament dimensions and acute tobacco withdrawalAdam M Leventhal
Center for Alcohol and Addiction Studies, Brown University, Box G S121, Providence, RI 02912, USA
Addict Behav 32:2976-89. 2007..Smokers with different temperaments display different patterns of acute tobacco withdrawal, and may benefit from treatments matched to their particular abstinence profile... - New lower nicotine cigarettes can produce compensatory smoking and increased carbon monoxide exposureAndrew A Strasser
Transdisciplinary Tobacco Use Research Center, University of Pennsylvania, 3535 Market Street, Suite 4100, Philadelphia, PA 19104, United States
Drug Alcohol Depend 86:294-300. 2007..Although marketed as a PREP, increases in CO boost suggest this product can potentially be a harm-increasing product... - Cigarette smoking and cervical cancer: Part II: a geographic variability studyStacey L Steckley
The Intramural Research Program (Addiction Research Center, National Institute on Drug Abuse, National Institutes of Health, 5500 Nathan Shock Drive, MD, Baltimore, USA
Biomed Pharmacother 57:78-83. 2003..It appears that smoking may play a prominent role in cervical cancer in developing countries, but less of a role in other countries... - History of marijuana use and tobacco smoking topography in tobacco-dependent adolescentsA Thiri Aung
Clinical Pharmacology and Treatment Research Branch, National Institutes of Health, National Institute on Drug Abuse, Intramural Research Program, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
Addict Behav 29:699-706. 2004..Our findings in adolescent smokers are consistent with results from adult studies in which history of MJ smoking was not associated with changes in tobacco smoking topography... - Risk factors predicting changes in marijuana involvement in teenagersMarianne B M van den Bree
Division of Psychological Medicine, College of Medicine, Cardiff University, Cardiff, Wales
Arch Gen Psychiatry 62:311-9. 2005..Prevention and/or intervention efforts should focus on these areas of risk... - Effects of cigarette nicotine content and smoking pace on subsequent craving and smokingJesse Dallery
Department of Psychology, University of Florida, P O Box 112250, Gainesville, FL 32611, USA
Psychopharmacology (Berl) 165:172-80. 2003..Rapid smoking procedures and denicotinized cigarettes can be used to further disentangle these factors, and to explore the relationship between craving and smoking... - Smoking topography and trajectory of asthmatic adolescents requesting cessation treatmentDarin M Zimmerman
Teen Tobacco Addiction Treatment Research Clinic, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, U.S. Department of Health and Human Services, Baltimore, MD 21224, USA
Prev Med 39:940-2. 2004..These findings highlight the need for more effective health counseling of asthmatic youth regarding the physical and behavioral effects of smoking...