Research Topics
| Yikyung ParkSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Dairy food, calcium, and risk of cancer in the NIH-AARP Diet and Health StudyYikyung Park
Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Bethesda, MD 20852, USA
Arch Intern Med 169:391-401. 2009..Dairy food and calcium intakes have been hypothesized to play roles that differ among individual cancer sites, but the evidence has been limited and inconsistent. Moreover, their effect on cancer in total is unclear...- Dietary fiber intake and risk of breast cancer in postmenopausal women: the National Institutes of Health-AARP Diet and Health StudyYikyung Park
Divisions of Cancer Epidemiology and Genetics and Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD, USA
Am J Clin Nutr 90:664-71. 2009..Although dietary fiber has been hypothesized to lower risk of breast cancer by modulating estrogen metabolism, the association between dietary fiber intake and risk of breast cancer by hormone receptor status is unclear... - Calcium, dairy foods, and risk of incident and fatal prostate cancer: the NIH-AARP Diet and Health StudyYikyung Park
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20852, USA
Am J Epidemiol 166:1270-9. 2007..04). Although the authors cannot definitively rule out a weak association for aggressive prostate cancer, their findings do not provide strong support for the hypothesis that calcium and dairy foods increase prostate cancer risk... - Dietary fiber intake and mortality in the NIH-AARP diet and health studyYikyung Park
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20852, USA
Arch Intern Med 171:1061-8. 2011..Dietary fiber has been hypothesized to lower the risk of coronary heart disease, diabetes, and some cancers. However, little is known of the effect of dietary fiber intake on total death and cause-specific deaths... - Fruit and vegetable intakes and risk of colorectal cancer in the NIH-AARP diet and health studyYikyung Park
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20852, USA
Am J Epidemiol 166:170-80. 2007..the lowest = 0.86, 95% confidence interval: 0.74, 0.99). Intake of fruits was not related to risk of colorectal cancer in men or women... - Physical activity and head and neck cancer riskMichael F Leitzmann
Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Cancer Causes Control 19:1391-9. 2008..To investigate the relation of physical activity to head and neck cancer... - Alcohol and risk of breast cancer by histologic type and hormone receptor status in postmenopausal women: the NIH-AARP Diet and Health StudyJasmine Q Lew
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, Rockville, MD 20852, USA
Am J Epidemiol 170:308-17. 2009..13 (95% CI: 0.73, 1.77) for >20 g versus 0 g/day, and 1.21 (95% CI: 0.79, 1.84) for >20 g versus 0 g/day, respectively. Moderate consumption of alcohol was associated with breast cancer, specifically hormone receptor-positive tumors... - Adolescent and mid-life diet: risk of colorectal cancer in the NIH-AARP Diet and Health StudyElizabeth H Ruder
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, MD
Am J Clin Nutr 94:1607-19. 2011..Colorectal cancer has a natural history of several decades; therefore, the diet consumed decades before diagnosis may aid in understanding this malignancy... - Association of meat and fat intake with liver disease and hepatocellular carcinoma in the NIH-AARP cohortNeal D Freedman
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, 6120 Executive Blvd, Rockville, MD 20852, USA
J Natl Cancer Inst 102:1354-65. 2010..Several plausible mechanisms, including fat, iron, heterocyclic amines, and N-nitroso compounds, link meat intake with chronic liver disease (CLD) and hepatocellular carcinoma (HCC). Few studies have investigated these associations... - Socioeconomic deprivation impact on meat intake and mortality: NIH-AARP Diet and Health StudyJacqueline M Major
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, 6120 Executive Boulevard, Rockville, MD 20852, USA
Cancer Causes Control 22:1699-707. 2011..This study examined the impact of area socioeconomic deprivation on the association between meat intake and all-cause and cause-specific mortality after accounting for individual-level risk factors... - Dietary fiber and whole-grain consumption in relation to colorectal cancer in the NIH-AARP Diet and Health StudyArthur Schatzkin
Division of Cancer Epidemiology, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
Am J Clin Nutr 85:1353-60. 2007..Whether the intake of dietary fiber can protect against colorectal cancer is a long-standing question of considerable public health import, but the epidemiologic evidence has been inconsistent... - Fruit and vegetable intake and head and neck cancer risk in a large United States prospective cohort studyNeal D Freedman
Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
Int J Cancer 122:2330-6. 2008..Results from this large prospective observational study are consistent with previous case-control studies and support the hypothesis that total fruit and vegetable intake is associated with reduced risk of head and neck cancer... - Age-specific physical activity and prostate cancer risk among white men and black menSteven C Moore
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
Cancer 115:5060-70. 2009..The authors investigated physical activity, including activity during different age periods and of various intensities, in relation to prostate cancer incidence among white men and black men... - Prospective study of physical activity and lung cancer by histologic type in current, former, and never smokersMichael F Leitzmann
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, USA
Am J Epidemiol 169:542-53. 2009..The inverse findings among former and current smokers in combination with the null results for physical activity among never smokers may point toward residual confounding by cigarette smoking as an explanation for the relations observed... - Prospective study of dietary fiber, whole grain foods, and small intestinal cancerArthur Schatzkin
Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20852, USA
Gastroenterology 135:1163-7. 2008..We conducted a prospective cohort study to determine the relationship between intake of dietary fiber/whole grains and the incidence of small intestinal cancer... - Dietary fiber and grain consumption in relation to head and neck cancer in the NIH-AARP Diet and Health StudyTram Kim Lam
Genetic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 20852, USA
Cancer Causes Control 22:1405-14. 2011..Dietary fiber and grain consumption may reduce the risk of head and neck cancer; however, the epidemiological evidence is limited. We investigated this relationship in the National Institutes of Health (NIH)-AARP Diet and Health Study... - Large prospective investigation of meat intake, related mutagens, and risk of renal cell carcinomaCarrie R Daniel
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, MD, USA
Am J Clin Nutr 95:155-62. 2012..The evidence for meat intake and renal cell carcinoma (RCC) risk is inconsistent. Mutagens related to meat cooking and processing, and variation by RCC subtype may be important to consider... - Body mass index, effect modifiers, and risk of pancreatic cancer: a pooled study of seven prospective cohortsLi Jiao
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
Cancer Causes Control 21:1305-14. 2010..To investigate whether the positive association of body mass index (BMI, kg/m(2)) with risk of pancreatic cancer is modified by age, sex, smoking status, physical activity, and history of diabetes... - Neighborhood socioeconomic deprivation and mortality: NIH-AARP diet and health studyJacqueline M Major
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
PLoS ONE 5:e15538. 2010.... - Physical activity and esophageal and gastric carcinoma in a large prospective studyMichael F Leitzmann
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
Am J Prev Med 36:112-9. 2009..Few studies have investigated the relationship of physical activity to esophageal and gastric carcinoma according to histology and anatomic site... - Alcoholic beverages and prostate cancer in a prospective US cohort studyJoanne L Watters
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
Am J Epidemiol 172:773-80. 2010..These findings suggest that higher alcohol consumption modestly increases nonadvanced prostate cancer risk... - Amount of time spent in sedentary behaviors and cause-specific mortality in US adultsCharles E Matthews
Nutritional Epidemiology Branch, National Cancer Institute, Rockville, MD, USA
Am J Clin Nutr 95:437-45. 2012..Sedentary behaviors predominate modern life, yet we do not fully understand the adverse effects of these behaviors on mortality after considering the benefits of moderate-vigorous physical activity (MVPA)... - Effect of changing breast cancer incidence rates on the calibration of the Gail modelSara J Schonfeld
Biostatistics Branch, Division of Cancer Epidemiology and Genetics, 6120 Executive Blvd, Bethesda, MD 20892, USA
J Clin Oncol 28:2411-7. 2010..Motivated by changes in breast cancer incidence during the 1990s, we evaluated the model's calibration in two recent cohorts... - A large prospective study of meat consumption and colorectal cancer risk: an investigation of potential mechanisms underlying this associationAmanda J Cross
Nutritional Epidemiology Branch, Biostatistics Branch, Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, NIH, Rockville, Maryland, USA
Cancer Res 70:2406-14. 2010..In conclusion, we found a positive association for red and processed meat intake and colorectal cancer; heme iron, nitrate/nitrite, and heterocyclic amines from meat may explain these associations... - Hormone-related risk factors and postmenopausal breast cancer among nulliparous versus parous women: An aggregated studySara J Schonfeld
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7238, USA
Am J Epidemiol 173:509-17. 2011..Although the baseline risk is higher for nulliparous women compared with parous women, these results suggest that the associations between hormone-related factors and breast cancer do not differ by parity... - Waist circumference as compared with body-mass index in predicting mortality from specific causesMichael F Leitzmann
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, U S Department of Health and Human Services, Bethesda, Maryland, United States of America
PLoS ONE 6:e18582. 2011..Whether waist circumference provides clinically meaningful information not delivered by body-mass index regarding prediction of cause-specific death is uncertain... - Physical activity in relation to total, advanced, and fatal prostate cancerSteven C Moore
Division of Cancer Epidemiology, National Cancer Institute, Bethesda, MD 20892, USA
Cancer Epidemiol Biomarkers Prev 17:2458-66. 2008..96; 95% CI, 0.67-1.36; P(trend) = 0.99). Neither vigorous exercise at baseline nor exercise during adolescence was related to risk of total, advanced, or fatal prostate cancer in this large prospective cohort... - Body mass index, physical activity, and bladder cancer in a large prospective studyCorinna Koebnick
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland, USA
Cancer Epidemiol Biomarkers Prev 17:1214-21. 2008..358), respectively. In conclusion, these findings provide support for a modest adverse effect of adiposity on risk for bladder cancer. In contrast, our results do not suggest a relation between physical activity and bladder cancer... - Fruit and vegetable intake and esophageal cancer in a large prospective cohort studyNeal D Freedman
Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
Int J Cancer 121:2753-60. 2007..A significant inverse association between EAC and Chenopodiaceae (spinach) intake was observed. Results from our study suggest that the relation of fruit and vegetable intake and esophageal cancer risk may vary by histologic type... - Prospective investigation of poultry and fish intake in relation to cancer riskCarrie R Daniel
Nutritional Epidemiology Branch, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Blvd, Suite 320, Rockville, MD 20852, USA
Cancer Prev Res (Phila) 4:1903-11. 2011..Simply increasing fish or poultry intake, without reducing red meat intake, may be less beneficial for cancer prevention... - Lifestyle factors and risk for new-onset diabetes: a population-based cohort studyJared P Reis
National Heart, Lung, and Blood Institute, Bethesda, MD, USA
Ann Intern Med 155:292-9. 2011..Epidemiologic data on the combined influence of several lifestyle factors on diabetes risk are rare, particularly among older adults... - Physical activity recommendations and decreased risk of mortalityMichael F Leitzmann
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
Arch Intern Med 167:2453-60. 2007..Whether national physical activity recommendations are related to mortality benefit is incompletely understood... - Body-mass index and mortality among 1.46 million white adultsAmy Berrington de Gonzalez
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
N Engl J Med 363:2211-9. 2010.... - Reproductive and hormonal factors and lung cancer risk in the NIH-AARP Diet and Health Study cohortLouise A Brinton
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD 20852, USA
Cancer Epidemiol Biomarkers Prev 20:900-11. 2011..Inconsistent findings about hormonal factors on risk may reflect incomplete control for confounding, misclassification of exposures, or insufficient attention to variation by histology... - Prospective study of body mass index, physical activity and thyroid cancerMichael F Leitzmann
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health DHHS, Bethesda, MD 20892, USA
Int J Cancer 126:2947-56. 2010..Based on only 15 cases, adiposity was unrelated to medullary thyroid cancers. Physical activity was unrelated to total thyroid cancer... - Physical activity, sedentary behavior, and the risk of colon and rectal cancer in the NIH-AARP Diet and Health StudyRegan A Howard
Division of Cancer Epidemiology and Genetics, Radiation Epidemiology Branch, National Cancer Institute, NIH, DHHS, Bethesda, MD, 20892, USA
Cancer Causes Control 19:939-53. 2008..In order to prospectively investigate physical activity at varying intensities and sedentary behavior in relation to colorectal cancer... - Alcohol and endometrial cancer risk in the NIH-AARP diet and health studyHannah P Yang
Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20852, USA
Int J Cancer 128:2953-61. 2011..Our results do not support that alcohol is a strong contributor to endometrial cancer risk, but slight risk increases may prevail among some users or for selected tumor characteristics... - Physical activity during adulthood and adolescence in relation to renal cell cancerSteven C Moore
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
Am J Epidemiol 168:149-57. 2008..82 (95% CI: 0.68, 1.00; p(trend) = 0.05) for activity during adolescence. The authors conclude that increased physical activity, including activity during adolescence, is associated with reduced risk of renal cell cancer... - Cigarette smoking and prostate cancer in a prospective US cohort studyJoanne L Watters
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland 20892, USA
Cancer Epidemiol Biomarkers Prev 18:2427-35. 2009..These findings suggest that current and former smokers may be at decreased risk of being diagnosed with prostate cancer and current smokers are at an increased risk of dying from prostate cancer... - Observational epidemiologic studies of nutrition and cancer: the next generation (with better observation)Arthur Schatzkin
National Cancer Institute, Bethseda, MD, USA
Cancer Epidemiol Biomarkers Prev 18:1026-32. 2009.... - Dietary nitrate and nitrite and the risk of thyroid cancer in the NIH-AARP Diet and Health StudyBriseis A Kilfoy
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852 7244, USA
Int J Cancer 129:160-72. 2011..74; 95%CI: 0.86-8.77; p-trend = 0.04) among men. Our results support a role of nitrate in thyroid cancer risk and suggest that further studies to investigate these exposures are warranted... - Nonsteroidal anti-inflammatory drugs and glioma in the NIH-AARP Diet and Health Study cohortSarah E Daugherty
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland, USA
Cancer Prev Res (Phila) 4:2027-34. 2011..90; 95% CI, 0.65-1.25 and HR for glioblastoma = 0.83; 95% CI, 0.56-1.20) as compared with no use. Our findings from this large prospective study do not support an inverse association between NSAIDs and risk of all glioma or glioblastoma... - Obesity and thyroid cancer risk among U.S. men and women: a pooled analysis of five prospective studiesCari M Kitahara
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD 20852, USA
Cancer Epidemiol Biomarkers Prev 20:464-72. 2011..Thyroid cancer incidence has risen dramatically in the United States since the early 1980s. Although the prevalence of obesity has doubled during this time period, the relationship between obesity and thyroid cancer is uncertain... - Body fat distribution, weight change during adulthood, and thyroid cancer risk in the NIH-AARP Diet and Health StudyCari M Kitahara
Division of Cancer Epidemiology and Genetics, NCI, National Institutes of Health, Rockville, MD 20852, USA
Int J Cancer 130:1411-9. 2012..No clear association for weight gain in later life was observed. These results support a potential role for hormonal and metabolic parameters common to central adiposity in thyroid carcinogenesis... - Prospective evaluation of risk factors for male breast cancerLouise A Brinton
Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852 7234, USA
J Natl Cancer Inst 100:1477-81. 2008..Differences in risk factors may reflect unique mechanisms associated with androgens and their ratio to bioavailable estrogens... - Mineral intake and lung cancer risk in the NIH-American Association of Retired Persons Diet and Health studySomdat Mahabir
Modifiable Risk Factors Branch, Epidemiology and Genetics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, 6130 Executive Boulevard, Bethesda, MD 20892, USA
Cancer Epidemiol Biomarkers Prev 19:1976-83. 2010..Due to dietary recall bias in case-control studies, our objective was to assess whether these findings hold in a prospective cohort study... - Meat and meat-related compounds and risk of prostate cancer in a large prospective cohort study in the United StatesRashmi Sinha
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
Am J Epidemiol 170:1165-77. 2009..There were no clear associations for fatal prostate cancer. Red and processed meat may be positively associated with prostate cancer via mechanisms involving heme iron, nitrite/nitrate, grilling/barbecuing, and benzo[a]pyrene... - Unopposed estrogen and estrogen plus progestin menopausal hormone therapy and lung cancer risk in the NIH-AARP Diet and Health Study CohortLouise A Brinton
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 20852, USA
Cancer Causes Control 23:487-96. 2012..Previous studies have reported that lung cancer risk may be decreased, increased, or unaffected by prior use of menopausal hormone therapy (MHT)... - Validation of a colorectal cancer risk prediction model among white patients age 50 years and olderYikyung Park
Division of Cancer Epidemiology and Genetics, Biostatistics Branch, Bethesda, MD 20852, USA
J Clin Oncol 27:694-8. 2009..Validation of an absolute risk prediction model for colorectal cancer (CRC) by using a large, population-based cohort... - Multivitamins, individual vitamin and mineral supplements, and risk of diabetes among older U.S. adultsYiqing Song
Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Diabetes Care 34:108-14. 2011..Understanding the relationship between multivitamin use and diabetes risk is important given the wide use of multivitamin supplements among U.S. adults... - Diabetes and risk of Parkinson's diseaseQun Xu
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA
Diabetes Care 34:910-5. 2011..To investigate the relationship between diabetes and future risk of Parkinson's disease (PD) among older U.S. adults... - Genome-wide association study reveals genetic risk underlying Parkinson's diseaseJavier Simon-Sanchez
Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA
Nat Genet 41:1308-12. 2009..14, P = 1.55 x 10(-5)). These data demonstrate an unequivocal role for common genetic variants in the etiology of typical PD and suggest population-specific genetic heterogeneity in this disease... - Added sugar and sugar-sweetened foods and beverages and the risk of pancreatic cancer in the National Institutes of Health-AARP Diet and Health StudyYing Bao
Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
Am J Clin Nutr 88:431-40. 2008..Although it has been hypothesized that hyperglycemia, hyperinsulinemia, and insulin resistance are involved in the development of pancreatic cancer, results from epidemiologic studies of added sugar intake are inconclusive... - Intakes of fruit, vegetables, and specific botanical groups in relation to lung cancer risk in the NIH-AARP Diet and Health StudyMargaret E Wright
Department of Pathology MC 847, College of Medicine, University of Illinois at Chicago, 840 South Wood Street, Room 130, Chicago, IL 60612, USA
Am J Epidemiol 168:1024-34. 2008..06). These results provide support for a protective role of specific botanical subgroups of fruits and vegetables in lung cancer prevention in men, although the findings could also be due to residual confounding by smoking or chance... - Dietary fiber intake and risk of colorectal cancer: a pooled analysis of prospective cohort studiesYikyung Park
Department of Nutrition, Harvard School of Public Health, Boston, Mass 02115, USA
JAMA 294:2849-57. 2005..However, after accounting for other dietary risk factors, high dietary fiber intake was not associated with a reduced risk of colorectal cancer...