Research Topics
| L K NiemanSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Prolactin as a Marker of Successful Catheterization during IPSS in Patients with ACTH-Dependent Cushing's SyndromeS T Sharma
Building 10 CRC 1 East Room 3140, 10 Center Drive, Bethesda, Maryland 20892 1109
J Clin Endocrinol Metab 96:3687-94. 2011..Confirmation of hypercortisolemia remains a prerequisite for IPSS. A normalized ratio of 0.7-1.3 was not diagnostic...- Efficacy and tolerability of CDB-2914 treatment for symptomatic uterine fibroids: a randomized, double-blind, placebo-controlled, phase IIb studyLynnette K Nieman
Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland, USA
Fertil Steril 95:767-72.e1-2. 2011..To evaluate the efficacy and tolerability of the P receptor modulator CDB-2914 (Ulipristal, CDB)... - Approach to the patient with an adrenal incidentalomaLynnette K Nieman
Program on Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 1109, USA
J Clin Endocrinol Metab 95:4106-13. 2010..For more indeterminate lesions, repeat evaluation for growth after 3-12 months is useful, with subsequent testing intervals based on the rate of growth... - Dynamic evaluation of adrenal hypofunctionL K Nieman
Pediatric and Reproductive Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892 1583, USA
J Endocrinol Invest 26:74-82. 2003..Ultimately, the choice of test should be individualized for each patient, with knowledge of the available reference assays and the vagaries of each test... - Evaluation and treatment of Cushing's syndromeLynnette K Nieman
Reproductive Biology and Medicine Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA
Am J Med 118:1340-6. 2005..The medical treatment of choice is ketoconazole. The prognosis is better for Cushing's disease and benign adrenal causes of Cushing's syndrome than adrenocortical cancer and malignant ACTH-producing tumors... - Diagnostic tests for Cushing's syndromeLynnette K Nieman
Pediatric and Reproductive Endocrinology Branch, National Institute of Child Health and Human Development NIH, Building 10, Room 9D42, 10 Center Drive MSC 1583, Bethesda, MD 20892, USA
Ann N Y Acad Sci 970:112-8. 2002.... - Management of surgically hypogonadal patients unable to take sex hormone replacement therapyLynnette K Nieman
Pediatric and Reproductive Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Building 10, Room 9D42 MSC 1583, 10 Center Drive, Bethesda, MD 20892, USA
Endocrinol Metab Clin North Am 32:325-36. 2003..Low dose local estrogen treatment is a promising approach for the latter complaints... - Addison's diseaseLynnette K Nieman
Reproductive and Biology Medicine Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
Clin Dermatol 24:276-80. 2006..Synthetic adrenocorticotropin 1-24 at a dose of 250 microg works well as a dynamic test. Elevated plasma levels of adrenocorticotropin and renin confirm the diagnosis. Treatment involves replacement of the deficient hormones... - Medical therapy of Cushing's diseaseLynnette K Nieman
Pediatric and Reproductive Endocrinology Branch, National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA
Pituitary 5:77-82. 2002..Mitotane and metyrapone may be effective as single agents, while aminoglutethimide generally must be given in combination. The intravenously-administered etomidate may used when patients cannot take medications by mouth... - Difficulty in the diagnosis of Cushing diseaseLynnette K Nieman
Reproductive Biology and Medicine Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA
Nat Clin Pract Endocrinol Metab 2:53-7; quiz following 57. 2006..Previous medication history included 2.5 mg lisinopril daily and 25.0 mg hydrochlorothiazide daily for 12 months... - Glucocorticoid excess and hypertensionSmita Baid
National Institute of Child Health and Human Development, National Institutes of Health, Building 10, Room 9D42 MSC 1583, 10 Center Drive, Bethesda, MD 20892 1583, USA
Curr Hypertens Rep 6:493-9. 2004..Although treatment of hypertension with available antihypertensive medications is only moderately successful, after cure of Cushing's syndrome, approximately 30% of patients have persistent hypertension... - Corticotropin-releasing hormone stimulation following low-dose dexamethasone administration. A new test to distinguish Cushing's syndrome from pseudo-Cushing's statesJ A Yanovski
Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892
JAMA 269:2232-8. 1993..CONCLUSION--The dexamethasone-CRH test is a more accurate test to distinguish Cushing's syndrome from pseudo-Cushing's states in patients with mild hypercortisolism... - Urine free cortisol in the high-dose dexamethasone suppression test for the differential diagnosis of the Cushing syndromeM R Flack
National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland
Ann Intern Med 116:211-7. 1992..The diagnostic performance of the test is improved by measuring both urine free cortisol and 17-hydroxysteroid excretion and by requiring greater suppression of both steroids... - Inferior petrosal sinus AVP in patients with Cushing's syndromeJ A Yanovski
Department of Diagnostic Radiology, Warren Grant Magnuson Clinical Center, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 1862, USA
Clin Endocrinol (Oxf) 47:199-206. 1997.... - The dexamethasone-suppressed corticotropin-releasing hormone stimulation test differentiates mild Cushing's disease from normal physiologyJ A Yanovski
Office of the Director, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 1862, USA
J Clin Endocrinol Metab 83:348-52. 1998..These results suggest that the Dex-CRH test may be useful in the evaluation of CS in patients without significant hypercortisoluria. However, its value in patients with episodic hormonogenesis has not been tested... - The hypoplastic inferior petrosal sinus: a potential source of false-negative results in petrosal sampling for Cushing's diseaseJ L Doppman
Diagnostic Radiology Department, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland 20892 1182, USA
J Clin Endocrinol Metab 84:533-40. 1999..We conclude that the presence of a unilateral hypoplastic or plexiform inferior petrosal sinus can result in anomalous drainage from the pituitary gland that may lead to false-negative sampling results in patients with Cushing's disease... - A single midnight serum cortisol measurement distinguishes Cushing's syndrome from pseudo-Cushing statesD A Papanicolaou
Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
J Clin Endocrinol Metab 83:1163-7. 1998..5 microg/dL at midnight discriminates CS from PCS with higher sensitivity than 24-h urinary cortisol or 17OHCS, or other individual or combined measures of serum cortisol... - Plasma levels of corticotropin-releasing hormone in the inferior petrosal sinuses of healthy volunteers, patients with Cushing's syndrome, and patients with pseudo-Cushing statesJ A Yanovski
Office of the Director, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland 20892, USA
J Clin Endocrinol Metab 83:1485-8. 1998..We conclude that inferior petrosal sinus human CRH levels are not easily measured in the inferior petrosal sinuses and cannot be used to determine whether individual patients may have hypersecretion of CRH causing their ACTH secretion... - Paradoxical response to dexamethasone in the diagnosis of primary pigmented nodular adrenocortical diseaseC A Stratakis
National Institutes of Health, Bethesda, Maryland 20892 1862, USA
Ann Intern Med 131:585-91. 1999..Primary pigmented nodular adrenocortical disease causes the Cushing syndrome in children and young adults and is most frequently associated with the Carney complex... - Role of preoperative iodocholesterol scintiscanning in patients undergoing adrenalectomy for Cushing's syndromeK C Yu
Surgical Metabolism Section, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Surgery 118:981-6; discussion 986-7. 1995..Iodocholesterol scintiscanning (IS) is a noninvasive, functional diagnostic test. We report our experience with IS as an adjunct for adrenal surgery for Cushing's syndrome... - Specificity of screening tests for Cushing's syndrome in an overweight and obese populationSmita K Baid
The Program in Reproductive and Adult Endocrinology, the Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 1109, USA
J Clin Endocrinol Metab 94:3857-64. 2009..Recent reports suggest a higher prevalence (1-5%) of Cushing's syndrome in certain patient populations with features of the disorder (e.g., diabetes), but the prevalence in the overweight and obese population is not known... - Persistence of dysmenorrhea and nonmenstrual pain after optimal endometriosis surgery may indicate adenomyosisJason D Parker
National Institutes of Health, Bethesda, Maryland 20892-1109, USA
Fertil Steril 86:711-5. 2006..This suggests that myometrial JZ abnormalities or adenomyosis may contribute to chronic pelvic pain in women with endometriosis... - Prolonged remission after long-term treatment with steroidogenesis inhibitors in Cushing's syndrome caused by ectopic ACTH secretionS T Sharma
Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Building 10, CRC, 1 East, Rm 3140, Bethesda, Maryland 20892 1109, USA
Eur J Endocrinol 166:531-6. 2012..The pathophysiology remains unclear but may involve several different mechanisms... - A comparison of immunometric and radioimmunoassay measurement of ACTH for the differential diagnosis of Cushing's syndromeJ R Lindsay
Reproductive Biology and Medicine Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda MD 20892-1109, USA
J Endocrinol Invest 29:983-8. 2006..0); c) during IPSS, IRMA had similar sensitivity (100%) and specificity (100 vs 83%) compared with ICMA or RIA (p=1.0). CONCLUSIONS: ACTH immunometric assays correlate closely to RIA and offer similar diagnostic utility... - High rates of autoimmune and endocrine disorders, fibromyalgia, chronic fatigue syndrome and atopic diseases among women with endometriosis: a survey analysisN Sinaii
Pediatric and Reproductive Endocrinology Branch, National Institute of Child Health and Human Development, NIH, 10 Center Drive, Building 10, Room 9D42, MSC 1583, Bethesda, MD 20892 1583, USA
Hum Reprod 17:2715-24. 2002..This study examined whether the prevalence of autoimmune, chronic pain and fatigue and atopic disorders is higher in women with endometriosis than in the general female population... - Assessing the effects of thyroid suppression on benign solitary thyroid nodules. A model for using quantitative research synthesisG Csako
Clinical Pathology Department, Clin Ctr, NIH, Bethesda, MD 20892 1508, USA
Medicine (Baltimore) 79:9-26. 2000..Finally, quantitative assessment of available evidence as described here may be applicable to the review of other controversial issues as well... - CD10 immunohistochemical staining enhances the histological detection of endometriosisClariss Potlog-Nahari
Pediatric and Reproductive Endocrinology Branch, National Institute of Child Health and Human Development, Bethesda, Maryland 20892 1583, USA
Fertil Steril 82:86-92. 2004..To determine whether the use of CD10 immunohistochemistry in addition to hematoxylin and eosin (H&E) staining would increase the sensitivity of surgically suspected endometriosis lesions... - Deficits in hippocampus-mediated Pavlovian conditioning in endogenous hypercortisolismChristian Grillon
Mood and Anxiety Disorders Program, National Institute of Mental Health, Bethesda, MD 20892 2670, USA
Biol Psychiatry 56:837-43. 2004..The aim of this study was to examine the performance of Cushing's syndrome patients on trace eyeblink conditioning, a cross-species, hippocampal-mediated test of learning and memory... - Recruitment and retention of women for clinical leiomyoma trialsDesireé McCarthy-Keith
Program in Reproductive and Adult Endocrinology, National Institute of Child Health and Human Development, NIH, Bethesda, MD 20892, United States
Contemp Clin Trials 31:44-8. 2010..Subject recruitment and retention in clinical leiomyoma trials is challenging. We evaluated strategies to increase patient enrollment and completion in leiomyoma trials... - Return of chronic pelvic pain from endometriosis after raloxifene treatment: a randomized controlled trialPamela Stratton
Reproductive Biology and Medicine Branch, National Institutes of Health, Bethesda, Maryland, USA
Obstet Gynecol 111:88-96. 2008..To evaluate whether 6 months of raloxifene was effective in treatment of chronic pelvic pain in women with endometriosis... - Using location, color, size, and depth to characterize and identify endometriosis lesions in a cohort of 133 womenBarbara J Stegmann
Reproductive Biology and Medicine Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 1109, USA
Fertil Steril 89:1632-6. 2008..To correlate histology with endometriosis characteristics... - Urine vascular endothelial growth factor-A is not a useful marker for endometriosisClariss Potlog-Nahari
Pediatric and Reproductive Endocrinology Branch, National Institute of Child Health and Human Development, Bethesda, Maryland 20892 1583, USA
Fertil Steril 81:1507-12. 2004..To determine whether urine VEGF is elevated in women with endometriosis... - Location, color, size, depth, and volume may predict endometriosis in lesions resected at surgeryPamela Stratton
Pediatric and Reproductive Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 1853, USA
Fertil Steril 78:743-9. 2002..To correlate the diagnosis of endometriosis in lesions excised at laparoscopy with pathologic diagnosis... - The role of [(18)F]fluorodeoxyglucose positron emission tomography and [(111)In]-diethylenetriaminepentaacetate-D-Phe-pentetreotide scintigraphy in the localization of ectopic adrenocorticotropin-secreting tumors causing Cushing's syndromeKarel Pacak
Pediatric and Reproductive Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 1583, USA
J Clin Endocrinol Metab 89:2214-21. 2004..As H-OCT identified a tumor in one patient with otherwise negative imaging, it should be considered only when other imaging modalities fail to localize the ACTH-secreting tumor in patients with EAS... - Diagnostic accuracy of laparoscopy, magnetic resonance imaging, and histopathologic examination for the detection of endometriosisPamela Stratton
Pediatric and Reproductive Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
Fertil Steril 79:1078-85. 2003..To evaluate the utility of fat-suppressed magnetic resonance imaging (MRI) in the diagnosis of endometriosis... - Development of the selective progesterone receptor modulator CDB-2914 for clinical indicationsDiana L Blithe
Department of Health and Human Services, National Institute of Child Health and Human Development, National Institutes of Health Building 61E, Room 8B13, Bethesda, MD 20892, USA
Steroids 68:1013-7. 2003..On average, CDB-2914 tends to lengthen the menstrual cycle by approximately 1-2 days although the amount of delay varies with timing in the menstrual cycle and dose... - Use of a parenteral propylene glycol-containing etomidate preparation for the long-term management of ectopic Cushing's syndromeJ Krakoff
National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85014, USA
J Clin Endocrinol Metab 86:4104-8. 2001..Parenteral propylene glycol containing etomidate can be used safely for a prolonged period to reduce hypercortisolemia in patients unable to take oral medications... - Radioimmunoassay and tandem mass spectrometry measurement of bedtime salivary cortisol levels: a comparison of assays to establish hypercortisolismSmita K Baid
Reproductive Biology and Medicine Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 1109, USA
J Clin Endocrinol Metab 92:3102-7. 2007..Although bedtime salivary cortisol measurement has been proposed as the optimal screening test for the diagnosis of Cushing's syndrome, its performance using commercially available assays has not been widely evaluated... - The diagnosis of Cushing's syndrome: an Endocrine Society Clinical Practice GuidelineLynnette K Nieman
Program on Reproductive and Adult Endocrinology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
J Clin Endocrinol Metab 93:1526-40. 2008..The objective of the study was to develop clinical practice guidelines for the diagnosis of Cushing's syndrome... - CDB-2914 for uterine leiomyomata treatment: a randomized controlled trialEric D Levens
Reproductive Biology and Medicine Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
Obstet Gynecol 111:1129-36. 2008..To evaluate whether 3-month administration of CDB-2914, a selective progesterone receptor modulator, reduces leiomyoma size and symptoms... - Surgical remission of pituitary adenomas confined to the neurohypophysis in Cushing's diseaseRobert J Weil
Surgical Neurology Branch, National Institutes of Neurological Disorders and Stroke, National Institutes of Health, Building 10, Room 5D37, MSC 1414, 9000 Rockville Pike, Bethesda, Maryland 20892-1414, USA
J Clin Endocrinol Metab 91:2656-64. 2006.... - Outcome of using the histological pseudocapsule as a surgical capsule in Cushing diseaseJay Jagannathan
Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA
J Neurosurg 111:531-9. 2009..In this study the authors examined the results of using the pseudocapsule as a surgical capsule in the resection of adenomas in patients with Cushing disease... - Diagnostic accuracy of chromogranin A and calcitonin precursors measurements for the discrimination of ectopic ACTH secretion from Cushing's diseaseMarina S Zemskova
The Program in Reproductive and Adult Endocrinology, the Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892 1109, USA
J Clin Endocrinol Metab 94:2962-5. 2009..Neuroendocrine tumors may secrete chromogranin A (CgA), calcitonin (CT), procalcitonin (ProCT), a fragment of the amino terminus of procalcitonin (NProCT), and/or ACTH... - Glucocorticoid excess during adolescence leads to a major persistent deficit in bone mass and an increase in central body fatV Abad
Pediatric and Reproductive Endocrinology Branch, National Institute of Child Health and Human Development, Bethesda, Maryland, USA
J Bone Miner Res 16:1879-85. 2001..These observations suggest that hypercortisolism (exogenous or endogenous) during adolescence may have persistent adverse effects on bone and fat mass... - Is there a therapeutic role for octreotide in patients with ectopic Cushing's syndrome?G I Uwaifo
Developmental Endocrinology Branch, NICHD, National Institutes of Health, Bethesda, MD, USA
J Endocrinol Invest 26:710-7. 2003..Before therapy an octreotide challenge test may predict therapeutic response. Cortisol levels should be monitored regularly on somatostatin analog therapy, because of its unpredictable long-term pharmacodynamic profile... - Endometrial effects of a single early luteal dose of the selective progesterone receptor modulator CDB-2914Pamela Stratton
Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD 20892 1109, USA
Fertil Steril 93:2035-41. 2010..To test potential contraceptive mechanisms of the selective P receptor modulator CDB-2914 in the early luteal phase... - Cushing's syndrome during pregnancy: personal experience and review of the literatureJohn R Lindsay
Reproductive Biology and Medicine Branch, National Institute for Child Health and Human Development, National Institutes of Health, Building 10, CRC, Room 1-3140, 10 Center Drive, Bethesda, Maryland 20892-1109, USA
J Clin Endocrinol Metab 90:3077-83. 2005..It is likely that earlier recognition and treatment would improve outcome. There is a need for development of criteria for interpretation of diagnostic tests and increased consideration of CS in pregnancy... - Jugular venous sampling: an alternative to petrosal sinus sampling for the diagnostic evaluation of adrenocorticotropic hormone-dependent Cushing's syndromeIoannis Ilias
Pediatric and Reproductive Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
J Clin Endocrinol Metab 89:3795-800. 2004..86% CI, 78-94%). Centers with limited sampling experience may choose to use the simpler JVS and refer patients for IPSS when the results are negative... - Long-term impaired quality of life in Cushing's syndrome despite initial improvement after surgical remissionJohn R Lindsay
Reproductive Biology and Medicine Branch, National Institute of Child Health and Human Development, National Institutes of Health, Building 10, Clinical Research Center, Room 1-3140, 10 Center Drive, Bethesda, MD 20892-1109, USA
J Clin Endocrinol Metab 91:447-53. 2006..At longer-term follow-up, however, there is residual impairment of HRQL. Determination of modifiable factors that contribute to impaired HRQL may help reduce the physical and psychosocial burden of this disease... - Reduced expression of biomarkers associated with the implantation window in women with endometriosisQingxiang Wei
Reproductive Biology and Medicine Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA
Fertil Steril 91:1686-91. 2009..To evaluate the expression of biomarkers of implantation, glycodelin A (GdA), osteopontin (OPN), lysophosphatidic acid receptor 3 (LPA3), and HOXA10, in eutopic endometrium of women with and without endometriosis... - Therapeutic doses of glucocorticoids: implications for oral medicineS K Baid
Reproductive Biology and Medicine Branch, National Institute of Child Health and Development, National Institutes of Health, Bethesda, MD 20892-1109, USA
Oral Dis 12:436-42. 2006..The aim of this review is to provide oral healthcare practitioners with a practical guide to commonly used glucocorticoids, their adverse effects, and perioperative use... - A change in pituitary magnetic resonance imaging protocol detects ACTH-secreting tumours in patients with previously negative resultsIffat N Chowdhury
Reproductive Biology and Medicine Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA
Clin Endocrinol (Oxf) 72:502-6. 2010..We hypothesized that specific MR scanning parameters influence detection of corticotropinomas... - Utility of various functional and anatomic imaging modalities for detection of ectopic adrenocorticotropin-secreting tumorsMarina S Zemskova
Building 10, CRC, 1 East, Room 1 3140, 10 Center Drive, MSC 1109, Bethesda, Maryland 20892 1109, USA
J Clin Endocrinol Metab 95:1207-19. 2010..Eight occult EAS patients had 64 +/- 58 (9-198) months follow-up; others had none. Conclusions: High sensitivity and PPV suggest thoracic CT/MRI plus LOCT scans for initial imaging, with lesion confirmation by two modalities... - Luteal phase dose-response relationships of the antiprogestin CDB-2914 in normally cycling womenMaureen D Passaro
Pediatric and Reproductive Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA
Hum Reprod 18:1820-7. 2003..Further study of CDB-2914 is needed to determine its clinical role... - Reduced dermatopontin expression is a molecular link between uterine leiomyomas and keloidsWilliam H Catherino
Pediatric and Reproductive Endocrinology Branch, National Institutes of Health, Bethesda, Maryland 20892-1583, USA
Genes Chromosomes Cancer 40:204-17. 2004..In particular, decreased expression of dermatopontin represents a molecular link between the leiomyoma and keloid phenotypes... - Ectopic luteinizing hormone secretion and anovulationBoaz Hirshberg
Transplantation and Autoimmunity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA
N Engl J Med 348:312-7. 2003 - Differential diagnosis and imaging in Cushing's syndromeJohn R Lindsay
Reproductive Biology and Medicine Branch, National Institute for Child Health and Human Development, National Institutes of Health, 10 Center Drive, Building 10, CRC 1-3140, Bethesda, MD 20892-1109, USA
Endocrinol Metab Clin North Am 34:403-21, x. 2005..This article focuses on current biochemical and radiologic strategies for the differential diagnosis of CS... - The Keeper, a menstrual collection device, as a potential cause of endometriosis and adenomyosisStacey Spechler
Pediatric and Reproductive Endocrinology Branch, National Institute of Child Health and Human Development NIH, Building 10, MSC 1583, 10 Center Drive, Bethesda, MD 20892 1583, USA
Gynecol Obstet Invest 56:35-7. 2003..We describe the case of a woman with a prior tubal ligation who after four years of regular use of the Keeper, a menstrual collecting device, developed endometriosis and adenomyosis... - Strategy for elucidating differentially expressed genes in leiomyomata identified by microarray technologyWilliam H Catherino
Pediatric and Reproductive Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
Fertil Steril 80:282-90. 2003..Our previous study identified several genes that might contribute to the fibroid phenotype. We therefore sought to confirm genes involved in three distinct signal transduction pathways... - Salivary glands as a potential gene transfer target for gene therapeutics of some monogenetic endocrine disordersAntonis Voutetakis
Gene Therapy and Therapeutics Branch, NIDCR, NIH, DHHS, Bethesda, Maryland 20892, USA
J Endocrinol 185:363-72. 2005.... - A pharmacokinetic and pharmacodynamic study of delayed- and extended-release hydrocortisone (Chronocort) vs. conventional hydrocortisone (Cortef) in the treatment of congenital adrenal hyperplasiaSomya Verma
Reproductive Biology and Medicine Branch, the Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA
Clin Endocrinol (Oxf) 72:441-7. 2010..We compared hormonal profiles during therapy with a new modified-release hydrocortisone (MR-HC), Chronocort, to conventional hydrocortisone (HC), Cortef, in patients with CAH... - Cushing's syndrome due to ectopic corticotropin secretion: twenty years' experience at the National Institutes of HealthIoannis Ilias
Pediatric and Reproductive Endocrinology Branch, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland 20892-1109, USA
J Clin Endocrinol Metab 90:4955-62. 2005..Initial failed localization is common and suggests pulmonary carcinoid. Although only 47% achieved cure, survival is good except in patients with small-cell lung cancer, medullary thyroid cancer, and gastrinoma... - The hypothalamic-pituitary-adrenal axis in pregnancy: challenges in disease detection and treatmentJohn R Lindsay
Reproductive Biology and Medicine Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892-1109, USA
Endocr Rev 26:775-99. 2005..Appropriate treatment and management of labor are reviewed... - Selective venous sampling for androgen-producing ovarian pathologyEric D Levens
Eunice Kenedy Shriver National Institute of Child Health and Human Development Bethesda, MD 20892, USA
Clin Endocrinol (Oxf) 70:606-14. 2009..Multiple diagnostic modalities may be needed to establish the source of excessive androgen production in women. The role of selective venous catheterization in this process has not been established fully... - A logistic model for the prediction of endometriosisBarbara J Stegmann
Reproductive Biology and Medicine Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 1109, USA
Fertil Steril 91:51-5. 2009..To develop a model that uses individual and lesion characteristics to help surgeons choose lesions that have a high probability of containing histologically confirmed endometriosis... - Spoiled gradient recalled acquisition in the steady state technique is superior to conventional postcontrast spin echo technique for magnetic resonance imaging detection of adrenocorticotropin-secreting pituitary tumorsNicholas Patronas
Department of Radiology, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland 20892-1583, USA
J Clin Endocrinol Metab 88:1565-9. 2003..4%). We recommend the addition of SPGR to SE sequences using pituitary-specific technical parameters to improve the MRI detection of ACTH-secreting pituitary tumors... - Effects of child- and adolescent-onset endogenous Cushing syndrome on bone mass, body composition, and growth: a 7-year prospective study into young adulthoodGary M Leong
Reproductive Biology and Medicine Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA
J Bone Miner Res 22:110-8. 2007..In 14 children followed for 3-7 years into young adulthood after cure of CS, whereas bone mass largely recovered, persisting increases in total body and visceral fat suggests an increase risk of the metabolic syndrome... - Magnetic resonance imaging and transvaginal ultrasound for determining fibroid burden: implications for research and clinical careEric D Levens
Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
Am J Obstet Gynecol 200:537.e1-7. 2009..To compare magnetic resonance and ultrasound imaging for uterine fibroid measurement... - Nighttime salivary cortisol: a useful test for the diagnosis of Cushing's syndromeDimitris A Papanicolaou
Department of Internal Medicine, Emory University, Atlanta, Georgia 30322, USA
J Clin Endocrinol Metab 87:4515-21. 2002..We concluded that bedtime salivary cortisol measurement is a practical and accurate screening test for the diagnosis of Cushing's syndrome... - Association of hypertension and hypokalemia with Cushing's syndrome caused by ectopic ACTH secretion: a series of 58 casesDavid J Torpy
University of Queensland, Department of Medicine, Greenslopes Hospital, Newdegate Street, Brisbane, Queensland 4120, Australia
Ann N Y Acad Sci 970:134-44. 2002.... - Cushing's syndromeJohn Newell-Price
Division of Clinical Sciences, University of Sheffield, Northern General Hospital, Sheffield, UK
Lancet 367:1605-17. 2006..Here, we review the current understanding of pathogenesis, clinical features, diagnostic, and differential diagnostic approaches. We provide diagnostic algorithms and recommendations for management... - Cushing's disease after surgical resection and radiation therapy for nonfunctioning pituitary adenomaSjoberg A Kho
Division of Endocrinology and Metabolism, SUNY School of Medicine, Stony Brook, New York, USA
Endocr Pract 8:292-5. 2002..In contrast, functioning pituitary tumors may have few compressive symptoms if they manifest with complaints attributable to excessive pituitary hormones... - Sex-related differences in stimulated hypothalamic-pituitary-adrenal axis during induced gonadal suppressionCatherine A Roca
Office of Special Populations, National Institute of Mental Health, Rockville, Maryland 20857, USA
J Clin Endocrinol Metab 90:4224-31. 2005..e. in the absence of characteristic differences in reproductive steroids)... - Aggressive pituitary tumors in MEN1: do they refute the two-hit model of tumorigenesis?Stephen J Marx
J Clin Endocrinol Metab 87:453-6. 2002 - Screening for reversible osteoporosis: is cortisol a culprit?Lynnette K Nieman
Ann Intern Med 147:582-4. 2007