R M Kedl

Summary

Affiliation: National Jewish Medical and Research Center

Country: USA

T cells compete for access to antigen-bearing antigen-presenting cells
R M Kedl
Cancer Research Institute, National Jewish Medical and Research Center Denver, Colorado 80206, USA
J Exp Med 192:1105-13. 2000
CD40 stimulation accelerates deletion of tumor-specific CD8(+) T cells in the absence of tumor-antigen vaccination
R M Kedl
Cancer Research Institute, Department of Immunology, National Jewish Medical and Research Center, Denver, CO 80206, USA
Proc Natl Acad Sci U S A 98:10811-6. 2001
Observation of antigen-dependent CD8+ T-cell/ dendritic cell interactions in vivo
B C Schaefer
National Jewish Medical and Research Center, 1400 Jackson Street, K512, Denver, Colorado 80206, USA
Cell Immunol 214:110-22. 2001

T cells compete for access to antigen-bearing antigen-presenting cells
R M Kedl
Cancer Research Institute, National Jewish Medical and Research Center Denver, Colorado 80206, USA
J Exp Med 192:1105-13. 2000
..These results imply that common properties of T cell responses, such as epitope dominance and secondary response affinity maturation, are the result of competitive interactions between antigen-bearing APC and T cell subsets...
CD40 stimulation accelerates deletion of tumor-specific CD8(+) T cells in the absence of tumor-antigen vaccination
R M Kedl
Cancer Research Institute, Department of Immunology, National Jewish Medical and Research Center, Denver, CO 80206, USA
Proc Natl Acad Sci U S A 98:10811-6. 2001
..These results demonstrate that opposing effects can be elicited by CD40 stimulation in vivo and suggest the need for caution in using this treatment for cancer patients...
Observation of antigen-dependent CD8+ T-cell/ dendritic cell interactions in vivo
B C Schaefer
National Jewish Medical and Research Center, 1400 Jackson Street, K512, Denver, Colorado 80206, USA
Cell Immunol 214:110-22. 2001
..Dendritic cells undergo specific morphologic changes following interactions with antigen-specific T cells...