Jing Huang

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi A genomewide study identifies the Wnt signaling pathway as a major target of p53 in murine embryonic stem cells
    Kyoung Hwa Lee
    Laboratory of Cancer Biology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 107:69-74. 2010
  2. ncbi G9a and Glp methylate lysine 373 in the tumor suppressor p53
    Jing Huang
    Laboratory of Cancer Biology and Genetics, NCI, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Biol Chem 285:9636-41. 2010
  3. ncbi Integrative genome-wide approaches in embryonic stem cell research
    Xinyue Zhang
    Laboratory of Cancer Biology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    Integr Biol (Camb) 2:510-6. 2010
  4. ncbi Targeting protein lysine methylation and demethylation in cancers
    Yunlong He
    Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA
    Acta Biochim Biophys Sin (Shanghai) 44:70-9. 2012
  5. ncbi Distinct Regulatory Mechanisms and Functions for p53-Activated and p53-Repressed DNA Damage Response Genes in Embryonic Stem Cells
    Mangmang Li
    Cancer and Stem Cell Epigenetics, Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA
    Mol Cell 46:30-42. 2012

Collaborators

Detail Information

Publications5

  1. ncbi A genomewide study identifies the Wnt signaling pathway as a major target of p53 in murine embryonic stem cells
    Kyoung Hwa Lee
    Laboratory of Cancer Biology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 107:69-74. 2010
    ..Our findings uncover a direct and functional connection between p53 and the Wnt signaling pathway, and expand the catalog of p53 regulated genes in mESCs...
  2. ncbi G9a and Glp methylate lysine 373 in the tumor suppressor p53
    Jing Huang
    Laboratory of Cancer Biology and Genetics, NCI, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Biol Chem 285:9636-41. 2010
    ..These data reveal a new methylation site within p53 mediated by the methylases G9a and Glp and indicate that G9a is a potential inhibitory target for cancer treatment...
  3. ncbi Integrative genome-wide approaches in embryonic stem cell research
    Xinyue Zhang
    Laboratory of Cancer Biology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    Integr Biol (Camb) 2:510-6. 2010
    ..To this end, we offer our perspectives on the future of genome-wide studies on stem cells...
  4. ncbi Targeting protein lysine methylation and demethylation in cancers
    Yunlong He
    Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA
    Acta Biochim Biophys Sin (Shanghai) 44:70-9. 2012
    ..We also discuss the potential and the caveats of targeting protein lysine methylation for the treatment of cancer...
  5. ncbi Distinct Regulatory Mechanisms and Functions for p53-Activated and p53-Repressed DNA Damage Response Genes in Embryonic Stem Cells
    Mangmang Li
    Cancer and Stem Cell Epigenetics, Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA
    Mol Cell 46:30-42. 2012
    ..Together, these results support a model where, in response to DNA damage, p53 affects the status of ES cells through activating differentiation-associated genes and repressing ES cell-enriched genes...