Odile GabaySummaryAffiliation: National Institutes of Health Country: USA Publications
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Osteoarthritis and obesity: experimental modelsOdile Gabay
Cartilage Biology and Orthopaedic Branch, Cartilage Molecular Genetic Group, 50 South Drive, Bldg 50, Room 1314, NIAMS, National Institute of Health, Bethesda, MD 20892, USA
Joint Bone Spine 75:675-9. 2008..The link between OA and obesity may not simply be due to high mechanical stresses applied on the tissues, but soluble mediators may play an important role in the onset of OA in obese patients...
Tumor necrosis factor ?-mediated cleavage and inactivation of SirT1 in human osteoarthritic chondrocytesMona Dvir-Ginzberg
National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, Maryland, USA
Arthritis Rheum 63:2363-73. 2011..This study was undertaken to test the hypothesis that SirT1 is adversely affected by TNF?, resulting in altered gene expression...
SirT1 enhances survival of human osteoarthritic chondrocytes by repressing protein tyrosine phosphatase 1B and activating the insulin-like growth factor receptor pathwayViktoria Gagarina
National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, Maryland 20892, USA
Arthritis Rheum 62:1383-92. 2010..We undertook the present study to assess the role of SirT1 in the survival of osteoarthritic (OA) chondrocytes in humans...
