Research Topics
| Rebecca L DunfeeSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
The HIV Env variant N283 enhances macrophage tropism and is associated with brain infection and dementiaRebecca L Dunfee
Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Boston, MA 02115, USA
Proc Natl Acad Sci U S A 103:15160-5. 2006..001). These findings suggest that the macrophage-tropic HIV Env variant N283 is associated with brain infection and dementia in vivo, representing an example of a HIV variant associated with a specific AIDS-related complication...
Asn 362 in gp120 contributes to enhanced fusogenicity by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with AIDSJasminka Sterjovski
Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Victoria, Australia
Retrovirology 4:89. 2007....
Enhanced macrophage tropism of HIV in brain and lymphoid tissues is associated with sensitivity to the broadly neutralizing CD4 binding site antibody b12Rebecca L Dunfee
Department of Cancer Immunology and AIDS, Dana Farber Cancer Institute, Boston MA, USA
Retrovirology 6:69. 2009..These findings suggest overlap between specific gp120 determinants in or near the b12 epitope and those conferring macrophage tropism...
Macrophage entry mediated by HIV Envs from brain and lymphoid tissues is determined by the capacity to use low CD4 levels and overall efficiency of fusionElaine R Thomas
Department of Cancer Immunology and AIDS, Dana Farber Cancer Institute, Boston, MA, USA
Virology 360:105-19. 2007....
Loss of the N-linked glycosylation site at position 386 in the HIV envelope V4 region enhances macrophage tropism and is associated with dementiaRebecca L Dunfee
Department of Cancer Immunology and AIDS, Dana Farber Cancer Institute, Boston, MA, USA
Virology 367:222-34. 2007....
High frequency of defective vpu compared with tat and rev genes in brain from patients with HIV type 1-associated dementiaElaine R Thomas
Department of Cancer Immunology and AIDS, Dana Farber Cancer Institute, Boston, MA 02115, USA
AIDS Res Hum Retroviruses 23:575-80. 2007....
Changes in the V3 region of gp120 contribute to unusually broad coreceptor usage of an HIV-1 isolate from a CCR5 Delta32 heterozygotePaul R Gorry
Department of Cancer Immunology and AIDS, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA
Virology 362:163-78. 2007....
