Research Topics
Species | Amanda J CrossSummaryAffiliation: National Institutes of Health Country: USA Publications
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Publications
Meat-related mutagens/carcinogens in the etiology of colorectal cancerAmanda J Cross
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland 20852, USA
Environ Mol Mutagen 44:44-55. 2004..Here, we review the current epidemiologic knowledge of meat-related mutagens, and evaluate the types of studies that may be required in the future to clarify the association between meat consumption and colorectal cancer...
A prospective study of red and processed meat intake in relation to cancer riskAmanda J Cross
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland, United States of America
PLoS Med 4:e325. 2007..We investigated whether red or processed meat intake increases cancer risk at a variety of sites...
A large prospective study of meat consumption and colorectal cancer risk: an investigation of potential mechanisms underlying this associationAmanda J Cross
Nutritional Epidemiology Branch, Biostatistics Branch, Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, NIH, Rockville, Maryland, USA
Cancer Res 70:2406-14. 2010..In conclusion, we found a positive association for red and processed meat intake and colorectal cancer; heme iron, nitrate/nitrite, and heterocyclic amines from meat may explain these associations...
Meat consumption and risk of esophageal and gastric cancer in a large prospective studyAmanda J Cross
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland 20852, USA
Am J Gastroenterol 106:432-42. 2011..Although there have been multiple studies of meat and colorectal cancer, other gastrointestinal malignancies are understudied...
The role of dietary factors in the epidemiology of non-Hodgkin's lymphomaAmanda J Cross
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA
Leuk Lymphoma 47:2477-87. 2006....
Urinary biomarkers of meat consumptionAmanda J Cross
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland 20852, USA
Cancer Epidemiol Biomarkers Prev 20:1107-11. 2011..One method to circumvent such errors is the use of biomarkers of dietary intake, but currently there are no accepted biomarkers for meat intake...
Iron homeostasis and distal colorectal adenoma risk in the prostate, lung, colorectal, and ovarian cancer screening trialAmanda J Cross
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, MD 20852, USA
Cancer Prev Res (Phila) 4:1465-75. 2011....
A prospective study of meat and fat intake in relation to small intestinal cancerAmanda J Cross
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland 20852, USA
Cancer Res 68:9274-9. 2008..72; 95% CI, 1.79-7.74 for each 10-g increase in intake per 1,000 kcal). Our findings suggest that the positive associations for meat intake reported in previous case-control studies may partly be explained by saturated fat intake...
Iron and colorectal cancer risk in the alpha-tocopherol, beta-carotene cancer prevention studyAmanda J Cross
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD, USA
Int J Cancer 118:3147-52. 2006..7, 95% CI = 1.4-15.1, p trend = 0.009). In summary, we found a significant inverse association between several serum iron indices and colon cancer risk...
A prospective study of meat and meat mutagens and prostate cancer riskAmanda J Cross
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland, USA
Cancer Res 65:11779-84. 2005..01-1.61). In conclusion, very well done meat was positively associated with prostate cancer risk. In addition, this study lends epidemiologic support to the animal studies, which have implicated PhIP as a prostate carcinogen...
Meat and meat-mutagen intake and risk of non-Hodgkin lymphoma: results from a NCI-SEER case-control studyAmanda J Cross
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD 20892, USA
Carcinogenesis 27:293-7. 2006..39 (0.22-0.70); P trend = 0.004]. Overall, our study suggests that consumption of meat, whether or not it is well-done, does not increase the risk of NHL. Furthermore, neither HCAs nor B[a]P from meat increase the risk of NHL...
Dietary meat intake in relation to colorectal adenoma in asymptomatic womenLeah M Ferrucci
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
Am J Gastroenterol 104:1231-40. 2009....
A prospective study of meat, cooking methods, meat mutagens, heme iron, and lung cancer risksNatasa Tasevska
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 7242, USA
Am J Clin Nutr 89:1884-94. 2009..Red and processed meat consumption may play a role in lung cancer pathogenesis because of these meats' fat and carcinogen content...
Adolescent and mid-life diet: risk of colorectal cancer in the NIH-AARP Diet and Health StudyElizabeth H Ruder
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, MD
Am J Clin Nutr 94:1607-19. 2011..Colorectal cancer has a natural history of several decades; therefore, the diet consumed decades before diagnosis may aid in understanding this malignancy...
Interleukin-6 as a potential indicator for prevention of high-risk adenoma recurrence by dietary flavonols in the polyp prevention trialGerd Bobe
Center for Cancer Research, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland, USA
Cancer Prev Res (Phila) 3:764-75. 2010..Our results suggest that serum IL-6 may serve as a risk indicator and as a response indicator to dietary flavonols for colorectal cancer prevention...
Association of meat and fat intake with liver disease and hepatocellular carcinoma in the NIH-AARP cohortNeal D Freedman
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, 6120 Executive Blvd, Rockville, MD 20852, USA
J Natl Cancer Inst 102:1354-65. 2010..Several plausible mechanisms, including fat, iron, heterocyclic amines, and N-nitroso compounds, link meat intake with chronic liver disease (CLD) and hepatocellular carcinoma (HCC). Few studies have investigated these associations...
Pancreatic cancer and exposure to dietary nitrate and nitrite in the NIH-AARP Diet and Health StudyBriseis Aschebrook-Kilfoy
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20892, USA
Am J Epidemiol 174:305-15. 2011..These results provide modest evidence that processed meat sources of dietary nitrate and nitrite may be associated with pancreatic cancer among men and provide no support for the hypothesis in women...
Dietary fatty acids and pancreatic cancer in the NIH-AARP diet and health studyAnne C M Thiebaut
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
J Natl Cancer Inst 101:1001-11. 2009..Previous research relating dietary fat, a modifiable risk factor, to pancreatic cancer has been inconclusive...
Hyperplastic polyps and the risk of adenoma recurrence in the polyp prevention trialAdeyinka O Laiyemo
Cancer Prevention Fellowship Program, Office of Preventive Oncology, National Cancer Institute, Bethesda, Maryland 20892, USA
Clin Gastroenterol Hepatol 7:192-7. 2009..Prospective information on the risk of adenoma recurrence associated with hyperplastic polyps is limited. We sought to investigate whether the coexistence of hyperplastic polyps with adenomas increases the risk of adenoma recurrence...
Xenobiotic metabolizing gene variants, dietary heterocyclic amine intake, and risk of prostate cancerStella Koutros
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland 20852, USA
Cancer Res 69:1877-84. 2009..The observed effect provides evidence to support the hypothesis that HCAs may act as promoters of malignant transformation by altering mitogenic signaling...
Prospective study of dietary fiber, whole grain foods, and small intestinal cancerArthur Schatzkin
Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20852, USA
Gastroenterology 135:1163-7. 2008..We conducted a prospective cohort study to determine the relationship between intake of dietary fiber/whole grains and the incidence of small intestinal cancer...
Large prospective investigation of meat intake, related mutagens, and risk of renal cell carcinomaCarrie R Daniel
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, MD, USA
Am J Clin Nutr 95:155-62. 2012..The evidence for meat intake and renal cell carcinoma (RCC) risk is inconsistent. Mutagens related to meat cooking and processing, and variation by RCC subtype may be important to consider...
Sugars in diet and risk of cancer in the NIH-AARP Diet and Health StudyNatasa Tasevska
Applied Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD 20892 7242, USA
Int J Cancer 130:159-69. 2012..Measurement error in FFQ-reported dietary sugars may have limited our ability to obtain more conclusive findings. Statistically significant associations observed for the rare cancers are of interest and warrant further investigation...
Meat, meat cooking methods and preservation, and risk for colorectal adenomaRashmi Sinha
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland, USA
Cancer Res 65:8034-41. 2005..04; 95% CI, 0.90-1.19). Our study of screening-detected colorectal adenomas shows that red meat and meat cooked at high temperatures are associated with an increased risk of colorectal adenoma...
Serum adiponectin, leptin, C-peptide, homocysteine, and colorectal adenoma recurrence in the Polyp Prevention TrialGerd Bobe
Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute NCI, NIH, Department of Health and Human Services DHHS, Bethesda, Maryland, USA
Cancer Epidemiol Biomarkers Prev 19:1441-52. 2010..Serum adiponectin, leptin, C-peptide, and homocysteine are indicators for obesity, hyperinsulinemia, and chronic inflammation, which have all been associated with colorectal cancer...
Dietary fiber and grain consumption in relation to head and neck cancer in the NIH-AARP Diet and Health StudyTram Kim Lam
Genetic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 20852, USA
Cancer Causes Control 22:1405-14. 2011..Dietary fiber and grain consumption may reduce the risk of head and neck cancer; however, the epidemiological evidence is limited. We investigated this relationship in the National Institutes of Health (NIH)-AARP Diet and Health Study...
Epithelial ovarian cancer and exposure to dietary nitrate and nitrite in the NIH-AARP Diet and Health StudyBriseis Aschebrook-Kilfoy
Occupational and Environmental Epidemiology Branch, DCEG, NCI, NIH, Rockville, Maryland 20852, USA
Eur J Cancer Prev 21:65-72. 2012..There were no clear differences in risk by histologic subtype of ovarian cancer. Our findings suggest that a role of dietary nitrate and nitrite in ovarian cancer risk should be followed in other large cohort studies...
Dopamine D2 receptor polymorphisms and adenoma recurrence in the Polyp Prevention TrialGwen Murphy
Cancer Prevention Fellowship Program, Office of Preventive Oncology, National Cancer Institute, Bethesda, MD 20892, USA
Int J Cancer 124:2148-51. 2009..Increased risk of adenoma recurrence as conferred by DRD2 genotypes may be related to difference in alcohol and fat intake across genotypes...
Do interleukin polymorphisms play a role in the prevention of colorectal adenoma recurrence by dietary flavonols?Gerd Bobe
Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
Eur J Cancer Prev 20:86-95. 2011..In conclusion, our results suggest that IL SNPs, in combination with a flavonol-rich diet or decreased serum IL, may lower the risk of adenoma recurrence...
Meat and meat mutagens and risk of prostate cancer in the Agricultural Health StudyStella Koutros
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, EPS 8111, Rockville, MD 20852, USA
Cancer Epidemiol Biomarkers Prev 17:80-7. 2008..96-1.59) and 1.20 (95% CI, 0.93-1.55), respectively] when the highest quintile was compared with the lowest. In conclusion, well and very well done meat was associated with an increased risk for prostate cancer in this cohort...
Intakes of red meat, processed meat, and meat mutagens increase lung cancer riskTram Kim Lam
Cancer Prevention Fellowship Program, Office of Preventive Oncology, National Cancer Institute, NIH, Department of Health and Human Services, corrected Bethesda, Maryland 20892 7236, USA
Cancer Res 69:932-9. 2009..In summary, red meat, processed meat, and meat mutagens were independently associated with increased risk of lung cancer...
Socioeconomic deprivation impact on meat intake and mortality: NIH-AARP Diet and Health StudyJacqueline M Major
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, 6120 Executive Boulevard, Rockville, MD 20852, USA
Cancer Causes Control 22:1699-707. 2011..This study examined the impact of area socioeconomic deprivation on the association between meat intake and all-cause and cause-specific mortality after accounting for individual-level risk factors...
Etiologic heterogeneity among non-Hodgkin lymphoma subtypesLindsay M Morton
Division of Cancer Epidemiology and Genetics, National Cancer Institute NCI, National Institutes of Health NIH, Rockville, MD, USA
Blood 112:5150-60. 2008....
No effect of meat, meat cooking preferences, meat mutagens or heme iron on lung cancer risk in the prostate, lung, colorectal and ovarian cancer screening trialNatasa Tasevska
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
Int J Cancer 128:402-11. 2011..In this population, we found no association between meat type, cooking method, doneness level or intake of specific meat mutagens or heme iron and lung cancer risk...
Utilization and yield of surveillance colonoscopy in the continued follow-up study of the polyp prevention trialAdeyinka O Laiyemo
Cancer Prevention Fellowship Program, Office of Preventive Oncology, National Cancer Institute, Bethesda, Maryland 20892, USA
Clin Gastroenterol Hepatol 7:562-7; quiz 497. 2009..We examined the use and yield of surveillance colonoscopy among participants in the Polyp Prevention Trial (PPT) after the 4-year dietary intervention trial ended...
Meat and meat-related compounds and risk of prostate cancer in a large prospective cohort study in the United StatesRashmi Sinha
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
Am J Epidemiol 170:1165-77. 2009..There were no clear associations for fatal prostate cancer. Red and processed meat may be positively associated with prostate cancer via mechanisms involving heme iron, nitrite/nitrate, grilling/barbecuing, and benzo[a]pyrene...
Adiposity in relation to colorectal adenomas and hyperplastic polyps in womenMichael F Leitzmann
The Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, National Institutes of Health, 6120 Executive Blvd, Bethesda, MD 20892, USA
Cancer Causes Control 20:1497-507. 2009..To examine whether BMI is independently related to colorectal adenomas and hyperplastic polyps...
Meat and components of meat and the risk of bladder cancer in the NIH-AARP Diet and Health StudyLeah M Ferrucci
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland, USA
Cancer 116:4345-53. 2010..The authors comprehensively investigated the association between meat and meat components and bladder cancer...
Prospective investigation of poultry and fish intake in relation to cancer riskCarrie R Daniel
Nutritional Epidemiology Branch, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Blvd, Suite 320, Rockville, MD 20852, USA
Cancer Prev Res (Phila) 4:1903-11. 2011..Simply increasing fish or poultry intake, without reducing red meat intake, may be less beneficial for cancer prevention...
Patterns of meat intake and risk of prostate cancer among African-Americans in a large prospective studyJacqueline M Major
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, 6120 Executive Boulevard, Rockville, MD 20852, USA
Cancer Causes Control 22:1691-8. 2011..The purpose of this study was to examine the association between type of meat intake and prostate cancer risk among African-American men...
Postpolypectomy colonoscopy surveillance guidelines: predictive accuracy for advanced adenoma at 4 yearsAdeyinka O Laiyemo
Cancer Prevention Fellowship Program, Biometry Research Group, Divisionof Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
Ann Intern Med 148:419-26. 2008..Lack of confidence in postpolypectomy surveillance guidelines may be a factor in the observed low adherence rates among providers...
Meat and meat-mutagen intake and pancreatic cancer risk in the NIH-AARP cohortRachael Z Stolzenberg-Solomon
National Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health Human Services, Rockville, MD 20852, USA
Cancer Epidemiol Biomarkers Prev 16:2664-75. 2007..006) increased risk in men and women combined. These findings support the hypothesis that meat intake, particularly meat cooked at high temperatures and associated mutagens, may play a role in pancreatic cancer development...
Non-steroidal anti-inflammatory drugs and colorectal cancer risk in a large, prospective cohortElizabeth H Ruder
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland, USA
Am J Gastroenterol 106:1340-50. 2011..We investigated NSAID use and colorectal adenocarcinoma by subsite, and among individuals with a family history of colon cancer in the National Institutes of Health-AARP Diet and Health Study...
A prospective study of serum C-reactive protein and colorectal cancer risk in menMarc J Gunter
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland 20852, USA
Cancer Res 66:2483-7. 2006..018). These results support the notion that chronic low-grade inflammation is a marker for increased risk of colorectal cancer...
Genomic methylation of leukocyte DNA in relation to colorectal adenoma among asymptomatic womenUnhee Lim
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, Maryland, USA
Gastroenterology 134:47-55. 2008..We examined genomic methylation of leukocyte DNA in relation to colorectal adenoma (CRA) among asymptomatic women (40-79 years of age) participating in a multicenter colonoscopy screening study (CONCeRN Study, 2000-2002)...
Processed meat intake, CYP2A6 activity and risk of colorectal adenomaMary H Ward
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7240, USA
Carcinogenesis 28:1210-6. 2007..Our results suggest that nitrite and nitrate intake from processed meat intake increases the risk of colorectal adenoma after accounting for HCA and PAH...
Sex disparities in colorectal cancer incidence by anatomic subsite, race and ageGwen Murphy
Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD
Int J Cancer 128:1668-75. 2011..These findings may partially reflect differences in screening experiences and access to medical care but also suggest that etiologic factors may be playing a role...
Meat intake and mortality: a prospective study of over half a million peopleRashmi Sinha
Division of Cancer Epidemiology and Genetics, National Cancer Institute Nutritional Epidemiology Branch, Rockville, MD 20852, USA
Arch Intern Med 169:562-71. 2009..High intakes of red or processed meat may increase the risk of mortality. Our objective was to determine the relations of red, white, and processed meat intakes to risk for total and cause-specific mortality...
Dietary lignan and proanthocyanidin consumption and colorectal adenoma recurrence in the Polyp Prevention TrialGerd Bobe
Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute NCI, National Institutes of Health NIH, Department of Health and Human Services DHHS, Frederick, MD, USA
Int J Cancer 130:1649-59. 2012..04). To conclude, dietary lignan and proanthocyanidin consumption were not generally related to colorectal adenoma recurrence; however, high lignan intake may increase the risk of adenoma recurrence in women...
Folate and MTHFR: risk of adenoma recurrence in the Polyp Prevention TrialGwen Murphy
Cancer Prevention Fellowship Program, Office of Preventive Oncology, Bethesda, MD, USA
Cancer Causes Control 19:751-8. 2008..A C/T transition at position 677 in the gene encoding methlylenetetrahydrofolate reductase (MTHFR C677T) has been reported to interact with folate intake to modulate colorectal adenoma recurrence or cancer risk...
Use of the predictive sugars biomarker to evaluate self-reported total sugars intake in the Observing Protein and Energy Nutrition (OPEN) studyNatasa Tasevska
Applied Research Program, Division of Cancer Control and Population Sciences, Nutritional Epidemiology, Branch, National Cancer Institute, 6130 Executive Blvd, EPN 3121, Bethesda, MD 20892, USA
Cancer Epidemiol Biomarkers Prev 20:490-500. 2011..A predictive biomarker for intake of total sugars was recently developed under controlled conditions. We used this biomarker to assess measurement error (ME) structure in self-reported intake of total sugars in free-living individuals...
Mendelian randomization: how it can--and cannot--help confirm causal relations between nutrition and cancerArthur Schatzkin
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA
Cancer Prev Res (Phila) 2:104-13. 2009..We conclude that Mendelian randomization is not universally applicable, but, under the right conditions, can complement evidence for causal associations from conventional epidemiologic studies...
Dietary factors and risk of chronic lymphocytic leukemia and small lymphocytic lymphoma: a pooled analysis of two prospective studiesHuei Ting Tsai
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland 20892, USA
Cancer Epidemiol Biomarkers Prev 19:2680-4. 2010..Very few studies have investigated diet in relation to these leukemias, and no consistent associations are known...
Trends in meat consumption in the USACarrie R Daniel
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd, Bethesda, MD 20892, USA
Public Health Nutr 14:575-83. 2011..To characterize the trends, distribution, potential determinants and public health implications of meat consumption within the USA...
Pooled analysis of genetic variation at chromosome 8q24 and colorectal neoplasia riskSonja I Berndt
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7240, USA
Hum Mol Genet 17:2665-72. 2008..008. This study confirms the association between colorectal neoplasia and the 8q24 polymorphisms located between 128.47 and 128.54 Mb and suggests a role for these variants in the formation of multiple adenomas...
Dietary flavonoids and colorectal adenoma recurrence in the Polyp Prevention TrialGerd Bobe
Laboratory of Cancer Prevention, National Cancer Institute Frederick, Room 110, Building 576, Frederick, MD 21702 1201, USA
Cancer Epidemiol Biomarkers Prev 17:1344-53. 2008..Our data suggest that a flavonol-rich diet may decrease the risk of advanced adenoma recurrence...
Diet and risk of multiple myeloma in Connecticut womenH Dean Hosgood
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 7240, USA
Cancer Causes Control 18:1065-76. 2007....
Heme iron from meat and risk of adenocarcinoma of the esophagus and stomachMary H Ward
Department of Health and Human Services, Occupational and Environmental Epidemiology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 7240, USA
Eur J Cancer Prev 21:134-8. 2012..Our results suggest that high intakes of heme and iron from meat may be important dietary risk factors for esophageal and stomach cancer and may partly explain associations with red meat...
Variability in fecal water genotoxicity, determined using the Comet assay, is independent of endogenous N-nitroso compound formation attributed to red meat consumptionAmanda J Cross
Medical Research Council Dunn Human Nutrition Unit, Cambridge, United Kingdom
Environ Mol Mutagen 47:179-84. 2006..0001). Failure to find dietary effects on fecal water genotoxicity may therefore be attributed to individual variability and low levels of ATNCs in fecal water samples...
Susceptibility of human metabolic phenotypes to dietary modulationCinzia Stella
Biomolecular Medicine, Division of Surgery, Oncology, Reproductive Biology and Anaesthetics (SORA, Faculty of Medicine, Imperial College London, and MRC Dunn Human Nutrition Unit, Addenbrookes Hospital, Cambridge, United Kingdom
J Proteome Res 5:2780-8. 2006..This work shows the potential for the routine use of metabonomics in nutritional and epidemiological studies, in characterizing and predicting the metabolic effects and the influence of diet on human metabotypes...
Red meat enhances the colonic formation of the DNA adduct O6-carboxymethyl guanine: implications for colorectal cancer riskMichelle H Lewin
Diet and Cancer Group, Dunn Human Nutrition Unit, Wellcome Trust/Medical Research Council Building, Cambridge CB2 2XY, United Kingdom
Cancer Res 66:1859-65. 2006..As these O(6)CMG adducts are not repaired, and if other related adducts are formed and not repaired, this may explain the association of red meat with colorectal cancer...
Pesticide use and colorectal cancer risk in the Agricultural Health StudyWon Jin Lee
Department of Preventive Medicine, College of Medicine, Korea University, Seoul, Korea
Int J Cancer 121:339-46. 2007..Nonetheless the possibility of an association between exposure to certain pesticides and incidence of colorectal cancer among pesticide applicators deserves further evaluation...
New marker of colon cancer risk associated with heme intake: 1,4-dihydroxynonane mercapturic acidFabrice Pierre
, , Toulouse, France
Cancer Epidemiol Biomarkers Prev 15:2274-9. 2006..CONCLUSION: Urinary DHN-MA is a useful noninvasive biomarker for determining the risk of preneoplastic lesions associated with heme iron consumption and should be further investigated as a potential biomarker of colon cancer risk...
