Peter D Crompton

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi Sickle cell trait is associated with a delayed onset of malaria: implications for time-to-event analysis in clinical studies of malaria
    Peter D Crompton
    Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20852, USA
    J Infect Dis 198:1265-75. 2008
  2. ncbi A prospective analysis of the Ab response to Plasmodium falciparum before and after a malaria season by protein microarray
    Peter D Crompton
    Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20852, USA
    Proc Natl Acad Sci U S A 107:6958-63. 2010
  3. ncbi The TLR9 ligand CpG promotes the acquisition of Plasmodium falciparum-specific memory B cells in malaria-naive individuals
    Peter D Crompton
    Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20852, USA
    J Immunol 182:3318-26. 2009
  4. ncbi In vitro growth-inhibitory activity and malaria risk in a cohort study in mali
    Peter D Crompton
    Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, 12441 Parklawn Drive, Twinbrook 2 Bldg, Room 200F, Rockville, MD 20832, USA
    Infect Immun 78:737-45. 2010
  5. ncbi The Plasmodium falciparum-specific human memory B cell compartment expands gradually with repeated malaria infections
    Greta E Weiss
    Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
    PLoS Pathog 6:e1000912. 2010
  6. ncbi A positive correlation between atypical memory B cells and Plasmodium falciparum transmission intensity in cross-sectional studies in Peru and Mali
    Greta E Weiss
    Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America
    PLoS ONE 6:e15983. 2011
  7. ncbi Atypical memory B cells are greatly expanded in individuals living in a malaria-endemic area
    Greta E Weiss
    Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852, USA
    J Immunol 183:2176-82. 2009
  8. ncbi Advances and challenges in malaria vaccine development
    Peter D Crompton
    Laboratory of Immunogenetics, National Institute of Allergy and Infectious Disease NIAID, NIH, Rockville, Maryland, USA
    J Clin Invest 120:4168-78. 2010
  9. ncbi High efficiency human memory B cell assay and its application to studying Plasmodium falciparum-specific memory B cells in natural infections
    Greta E Weiss
    Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland 20852, USA
    J Immunol Methods 375:68-74. 2012

Collaborators

Detail Information

Publications9

  1. ncbi Sickle cell trait is associated with a delayed onset of malaria: implications for time-to-event analysis in clinical studies of malaria
    Peter D Crompton
    Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20852, USA
    J Infect Dis 198:1265-75. 2008
    ..Although common red blood cell (RBC) polymorphisms such as sickle hemoglobin (HbS) are known to protect against malaria in Africa, their impact on this end point has not been investigated...
  2. ncbi A prospective analysis of the Ab response to Plasmodium falciparum before and after a malaria season by protein microarray
    Peter D Crompton
    Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20852, USA
    Proc Natl Acad Sci U S A 107:6958-63. 2010
    ....
  3. ncbi The TLR9 ligand CpG promotes the acquisition of Plasmodium falciparum-specific memory B cells in malaria-naive individuals
    Peter D Crompton
    Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20852, USA
    J Immunol 182:3318-26. 2009
    ..These results provide important insights into the human MBC response, which can inform the development of vaccines against malaria and other pathogens that disrupt immunological memory...
  4. ncbi In vitro growth-inhibitory activity and malaria risk in a cohort study in mali
    Peter D Crompton
    Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, 12441 Parklawn Drive, Twinbrook 2 Bldg, Room 200F, Rockville, MD 20832, USA
    Infect Immun 78:737-45. 2010
    ..These data suggest that antibodies which block merozoite invasion of RBC and/or inhibit the intra-RBC growth of the parasite contribute to but are not sufficient for the acquisition of malaria immunity...
  5. ncbi The Plasmodium falciparum-specific human memory B cell compartment expands gradually with repeated malaria infections
    Greta E Weiss
    Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
    PLoS Pathog 6:e1000912. 2010
    ..These observations lend new insights into the cellular basis of the delayed acquisition of malaria immunity...
  6. ncbi A positive correlation between atypical memory B cells and Plasmodium falciparum transmission intensity in cross-sectional studies in Peru and Mali
    Greta E Weiss
    Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America
    PLoS ONE 6:e15983. 2011
    ..In this study we examined B cell subsets of Pf -infected adults in Peru and Mali to determine if Pf transmission intensity correlates with atypical memory B cell expansion...
  7. ncbi Atypical memory B cells are greatly expanded in individuals living in a malaria-endemic area
    Greta E Weiss
    Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852, USA
    J Immunol 183:2176-82. 2009
    ..This is the first description of an atypical MBC phenotype associated with malaria. Understanding the origin and function of these MBCs could be important in informing the design of malaria vaccines...
  8. ncbi Advances and challenges in malaria vaccine development
    Peter D Crompton
    Laboratory of Immunogenetics, National Institute of Allergy and Infectious Disease NIAID, NIH, Rockville, Maryland, USA
    J Clin Invest 120:4168-78. 2010
    ..A better understanding of the mechanisms of naturally acquired immunity to malaria may lead to insights for vaccine development...
  9. ncbi High efficiency human memory B cell assay and its application to studying Plasmodium falciparum-specific memory B cells in natural infections
    Greta E Weiss
    Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland 20852, USA
    J Immunol Methods 375:68-74. 2012
    ..Thus, this highly efficient assay appears to be well suited to field studies of the generation and maintenance of MBCs where the volumes of blood obtainable are often limiting...