Research Topics
| Riccardo Cassiani IngoniSummaryAffiliation: National Institutes of Health Country: USA Publications
| Collaborators
|
Detail Information
Publications
Disease progression after bone marrow transplantation in a model of multiple sclerosis is associated with chronic microglial and glial progenitor responseRiccardo Cassiani-Ingoni
Neuroimmunology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA
J Neuropathol Exp Neurol 66:637-49. 2007..Our data indicate that reactivation of a local inflammatory process after BMT is sustained predominantly by endogenous microglia/macrophages...
Borrelia burgdorferi Induces TLR1 and TLR2 in human microglia and peripheral blood monocytes but differentially regulates HLA-class II expressionRiccardo Cassiani-Ingoni
Cellular Immunology Section, Neuroimmunology Branch, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA
J Neuropathol Exp Neurol 65:540-8. 2006..burgdorferi can elicit opposite immunoregulatory effects in blood and in brain immune cells, which could play a role in the different susceptibility of these compartments to infection...
Cytoplasmic translocation of Olig2 in adult glial progenitors marks the generation of reactive astrocytes following autoimmune inflammationRiccardo Cassiani-Ingoni
Cellular Immunology Section, Neuroimmunology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
Exp Neurol 201:349-58. 2006..Together, these data ascribe a pivotal role to Olig2+ glial precursor cells in the adult CNS, linking autoimmune inflammation and glial scar formation...
Thymic output generates a new and diverse TCR repertoire after autologous stem cell transplantation in multiple sclerosis patientsPaolo A Muraro
Neuroimmunology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
J Exp Med 201:805-16. 2005....
Evidence that nucleocytoplasmic Olig2 translocation mediates brain-injury-induced differentiation of glial precursors to astrocytesTim Magnus
Laboratory of Neurosciences, National Institute on Aging Intramural Research Program, National Institutes of Health, Baltimore, Maryland 21224, USA
J Neurosci Res 85:2126-37. 2007..In contrast, neural stem cells and neuronal progenitor cells appear to play only a minor role in the injured adult CNS...
Clonotypic analysis of cerebrospinal fluid T cells during disease exacerbation and remission in a patient with multiple sclerosisPaolo A Muraro
Neuroimmunology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bldg 10, Room 5B16, 10 Center Dr MSC1400 Bethesda, MD 20892 1400, USA
J Neuroimmunol 171:177-83. 2006..CDR3 spectratyping is a valuable approach to identify disease-associated T cells in the CNS...
CD45-positive blood cells give rise to uterine epithelial cells in miceAndras Bratincsak
National Institute of Mental Health, Bethesda, Maryland, USA
Stem Cells 25:2820-6. 2007....
CD46 on glial cells can function as a receptor for viral glycoprotein-mediated cell-cell fusionRiccardo Cassiani-Ingoni
Neuroimmunology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
Glia 52:252-8. 2005..These data suggest a mechanism that involves cell-cell fusion by which certain viruses could spread the infection from the periphery to the cells in the nervous system...
Hematopoietic stem cell transplantation for multiple sclerosis: current status and future challengesPaolo A Muraro
Neuroimmunology Branch, National Institute of Neurological Diseases and Stroke, National Institutes of Health, MSC1400 Bethesda, MD 20892-1400, USA
Curr Opin Neurol 16:299-305. 2003..Recent advances on the migratory potential and on the differentiation plasticity of hematopoietic stem cells have opened new opportunities for remyelination and axonal repair strategies for multiple sclerosis...
Variant-specific tropism of human herpesvirus 6 in human astrocytesDonatella Donati
Viral Immunology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
J Virol 79:9439-48. 2005..Astrocytes may be an important reservoir for this virus in which differential tropism of HHV-6A and HHV-6B may be associated with different disease outcomes...
Revisiting the astrocyte-oligodendrocyte relationship in the adult CNSJessica Carmen
Laboratory of Neurosciences, National Institute on Aging Intramural Research Program, NIH, Baltimore, MD 21224, USA
Prog Neurobiol 82:151-62. 2007..Ideally, better understanding the origin of new glial cells in the injured CNS will facilitate the development of therapeutics targeted to alter the glial response in a beneficial way...
