Paul Badenhorst

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi A misexpression screen to identify regulators of Drosophila larval hemocyte development
    Martin Stofanko
    Institute of Biomedical Research, University of Birmingham, Edgbaston B15 2TT, United Kingdom
    Genetics 180:253-67. 2008
  2. ncbi Tramtrack controls glial number and identity in the Drosophila embryonic CNS
    P Badenhorst
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK
    Development 128:4093-101. 2001
  3. ncbi Tramtrack co-operates to prevent inappropriate neural development in Drosophila
    Paul Badenhorst
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, England, UK
    Mech Dev 117:87-101. 2002
  4. ncbi End of the line? Tramtrack and cell fate determination in Drosophila
    P Badenhorst
    MRC Laboratory of Molecular Biology, Cambridge, UK
    Genes Cells 1:707-16. 1996
  5. ncbi Tramtrack69 interacts with the dMi-2 subunit of the Drosophila NuRD chromatin remodelling complex
    C M Murawsky
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK
    EMBO Rep 2:1089-94. 2001
  6. ncbi The Drosophila selenoprotein BthD is required for survival and has a role in salivary gland development
    So Yeon Kwon
    Basic Research Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Mol Cell Biol 23:8495-504. 2003
  7. ncbi Biological functions of the ISWI chromatin remodeling complex NURF
    Paul Badenhorst
    Laboratory of Molecular Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda Maryland 20892 4255, USA
    Genes Dev 16:3186-98. 2002
  8. ncbi The Drosophila nucleosome remodeling factor NURF is required for Ecdysteroid signaling and metamorphosis
    Paul Badenhorst
    Laboratory of Molecular Cell Biology, National Cancer Institute, NIH, Bethesda, Maryland 20814, USA
    Genes Dev 19:2540-5. 2005
  9. ncbi The nucleosome remodeling factor (NURF) regulates genes involved in Drosophila innate immunity
    So Yeon Kwon
    Institute of Biomedical Research, University of Birmingham, Edgbaston, B15 2TT, UK
    Dev Biol 316:538-47. 2008

Collaborators

Detail Information

Publications9

  1. ncbi A misexpression screen to identify regulators of Drosophila larval hemocyte development
    Martin Stofanko
    Institute of Biomedical Research, University of Birmingham, Edgbaston B15 2TT, United Kingdom
    Genetics 180:253-67. 2008
    ..We have further analyzed three candidate genes for changes in hemocyte morphology, cell-cell adhesion properties, phagocytosis activity, and melanotic tumor formation...
  2. ncbi Tramtrack controls glial number and identity in the Drosophila embryonic CNS
    P Badenhorst
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK
    Development 128:4093-101. 2001
    ..I propose that Tramtrack ensures stable mature glial identity by both repressing neuroblast-specific genes and controlling glial cell proliferation...
  3. ncbi Tramtrack co-operates to prevent inappropriate neural development in Drosophila
    Paul Badenhorst
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, England, UK
    Mech Dev 117:87-101. 2002
    ..We show that the Ttk BTB domain is a protein-protein interaction motif mediating tetramer formation...
  4. ncbi End of the line? Tramtrack and cell fate determination in Drosophila
    P Badenhorst
    MRC Laboratory of Molecular Biology, Cambridge, UK
    Genes Cells 1:707-16. 1996
    ....
  5. ncbi Tramtrack69 interacts with the dMi-2 subunit of the Drosophila NuRD chromatin remodelling complex
    C M Murawsky
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK
    EMBO Rep 2:1089-94. 2001
    ..We also demonstrate that dMi-2 and Ttk interact genetically, indicating a functional interaction in vivo. We propose that Ttk69 represses some target genes by remodelling chromatin structure through the recruitment of the dNuRD complex...
  6. ncbi The Drosophila selenoprotein BthD is required for survival and has a role in salivary gland development
    So Yeon Kwon
    Basic Research Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Mol Cell Biol 23:8495-504. 2003
    ..Duplex RNAi induced from this construct targeted BthD mRNA for destruction and reduced BthD protein levels. We found that loss of BthD compromised salivary gland morphogenesis and reduced animal viability...
  7. ncbi Biological functions of the ISWI chromatin remodeling complex NURF
    Paul Badenhorst
    Laboratory of Molecular Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda Maryland 20892 4255, USA
    Genes Dev 16:3186-98. 2002
    ..Finally, mutants in NURF subunits exhibit neoplastic transformation of larval blood cells that causes melanotic tumors to form...
  8. ncbi The Drosophila nucleosome remodeling factor NURF is required for Ecdysteroid signaling and metamorphosis
    Paul Badenhorst
    Laboratory of Molecular Cell Biology, National Cancer Institute, NIH, Bethesda, Maryland 20814, USA
    Genes Dev 19:2540-5. 2005
    ..Moreover, purified NURF binds EcR in an ecdysone-dependent manner, suggesting it is a direct effector of nuclear receptor activity. The conservation of NURF in mammals has broad implications for steroid signaling...
  9. ncbi The nucleosome remodeling factor (NURF) regulates genes involved in Drosophila innate immunity
    So Yeon Kwon
    Institute of Biomedical Research, University of Birmingham, Edgbaston, B15 2TT, UK
    Dev Biol 316:538-47. 2008
    ..Chromatin immunoprecipitation (ChIP) localizes NURF to Ken-binding sites in hemocytes, suggesting that Ken recruits NURF to repress STAT responders. Loss of NURF leads to precocious activation of STAT target genes...