D Zamarin

Summary

Affiliation: Mount Sinai School of Medicine
Country: USA

Publications

  1. ncbi Enhancement of oncolytic properties of recombinant newcastle disease virus through antagonism of cellular innate immune responses
    Dmitriy Zamarin
    Department of Medicine, Mount Sinai School of Medicine, New York, New York 10029, USA
    Mol Ther 17:697-706. 2009
  2. ncbi Genetically engineered Newcastle disease virus for malignant melanoma therapy
    D Zamarin
    Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
    Gene Ther 16:796-804. 2009
  3. ncbi The immunological potency and therapeutic potential of a prototype dual vaccine against influenza and Alzheimer's disease
    Hayk Davtyan
    Department of Molecular Immunology, Institute for Molecular Medicine, Huntington Beach, CA 92647, USA
    J Transl Med 9:127. 2011
  4. ncbi Differential IL-10R1 expression plays a critical role in IL-10-mediated immune regulation
    Y Ding
    Institute for Gene Therapy and Molecular Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Immunol 167:6884-92. 2001
  5. ncbi Nuclear localization of the Nipah virus W protein allows for inhibition of both virus- and toll-like receptor 3-triggered signaling pathways
    Megan L Shaw
    Department of Microbiology, Box 1124, Mount Sinai School of Medicine, One Gustave L Levy Pl, New York, NY 10029, USA
    J Virol 79:6078-88. 2005
  6. ncbi Detection of free peritoneal cancer cells in gastric cancer using cancer-specific Newcastle disease virus
    Joyce Wong
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Gastrointest Surg 14:7-14. 2010
  7. ncbi Sequence analysis and receptor specificity of the hemagglutinin of a recent influenza H2N2 virus isolated from chicken in North America
    Laurel Glaser
    Department of Microbiology, Mount Sinai School of Medicine, New York, NY 10029, USA
    Glycoconj J 23:93-9. 2006
  8. ncbi Influenza A virus PB1-F2 protein contributes to viral pathogenesis in mice
    Dmitriy Zamarin
    Department of Microbiology, Box 1124, Mount Sinai School of Medicine, 1 Gustave Levy Place, New York, NY 10029, USA
    J Virol 80:7976-83. 2006
  9. ncbi Antitumor efficacy of viral therapy using genetically engineered Newcastle disease virus [NDV(F3aa)-GFP] for peritoneally disseminated gastric cancer
    Kyo Young Song
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Mol Med (Berl) 88:589-96. 2010
  10. ncbi A single amino acid substitution in 1918 influenza virus hemagglutinin changes receptor binding specificity
    Laurel Glaser
    Department of Microbiology, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Virol 79:11533-6. 2005

Collaborators

Detail Information

Publications12

  1. ncbi Enhancement of oncolytic properties of recombinant newcastle disease virus through antagonism of cellular innate immune responses
    Dmitriy Zamarin
    Department of Medicine, Mount Sinai School of Medicine, New York, New York 10029, USA
    Mol Ther 17:697-706. 2009
    ..These findings demonstrate that modulation of innate immune responses by NDV results in enhancement of its oncolytic properties and warrant further investigation of this strategy in design of oncolytic NDV vectors against human tumors...
  2. ncbi Genetically engineered Newcastle disease virus for malignant melanoma therapy
    D Zamarin
    Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
    Gene Ther 16:796-804. 2009
    ..These findings warrant further investigations of IL-2-expressing NDV as an antimelanoma agent in humans...
  3. ncbi The immunological potency and therapeutic potential of a prototype dual vaccine against influenza and Alzheimer's disease
    Hayk Davtyan
    Department of Molecular Immunology, Institute for Molecular Medicine, Huntington Beach, CA 92647, USA
    J Transl Med 9:127. 2011
    ..We hypothesized that in elderly people with pre-existing memory Th cells specific to influenza this dual vaccine will simultaneously boost anti-influenza immunity and induce production of therapeutically active anti-A? antibodies...
  4. ncbi Differential IL-10R1 expression plays a critical role in IL-10-mediated immune regulation
    Y Ding
    Institute for Gene Therapy and Molecular Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Immunol 167:6884-92. 2001
    ..Modulation of cell surface IL-10R1 density might be an important mechanism for determining whether IL-10 leads to immunostimulation or immunosuppression in vivo...
  5. ncbi Nuclear localization of the Nipah virus W protein allows for inhibition of both virus- and toll-like receptor 3-triggered signaling pathways
    Megan L Shaw
    Department of Microbiology, Box 1124, Mount Sinai School of Medicine, One Gustave L Levy Pl, New York, NY 10029, USA
    J Virol 79:6078-88. 2005
    ....
  6. ncbi Detection of free peritoneal cancer cells in gastric cancer using cancer-specific Newcastle disease virus
    Joyce Wong
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Gastrointest Surg 14:7-14. 2010
    ..We evaluated a novel detection technique using Newcastle disease virus expressing the enhanced green fluorescent protein (NDV-GFP) gene...
  7. ncbi Sequence analysis and receptor specificity of the hemagglutinin of a recent influenza H2N2 virus isolated from chicken in North America
    Laurel Glaser
    Department of Microbiology, Mount Sinai School of Medicine, New York, NY 10029, USA
    Glycoconj J 23:93-9. 2006
    ..Sequence analysis revealed that this HA is a member of the Eurasian clade, and receptor binding studies show that it maintains its specificity for the avian influenza virus alpha2-3 linked sialic acid receptor...
  8. ncbi Influenza A virus PB1-F2 protein contributes to viral pathogenesis in mice
    Dmitriy Zamarin
    Department of Microbiology, Box 1124, Mount Sinai School of Medicine, 1 Gustave Levy Place, New York, NY 10029, USA
    J Virol 80:7976-83. 2006
    ....
  9. ncbi Antitumor efficacy of viral therapy using genetically engineered Newcastle disease virus [NDV(F3aa)-GFP] for peritoneally disseminated gastric cancer
    Kyo Young Song
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Mol Med (Berl) 88:589-96. 2010
    ..These data provide further rationale for clinical trials involving NDV for peritoneal carcinomatosis from gastric cancer...
  10. ncbi A single amino acid substitution in 1918 influenza virus hemagglutinin changes receptor binding specificity
    Laurel Glaser
    Department of Microbiology, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Virol 79:11533-6. 2005
    ..Mutation of this single amino acid back to the avian consensus resulted in a preference for the avian receptor...
  11. ncbi Attenuation of equine influenza viruses through truncations of the NS1 protein
    Michelle Quinlivan
    Department of Microbiology, Box 1124, Mount Sinai School of Medicine, 1 Gustave Levy Place, New York, New York 10029, USA
    J Virol 79:8431-9. 2005
    ..Therefore, these attenuated mutant NS1 viruses may have potential as candidates for a live equine influenza vaccine...
  12. ncbi A single mutation in the PB1-F2 of H5N1 (HK/97) and 1918 influenza A viruses contributes to increased virulence
    Gina M Conenello
    Department of Microbiology, Mount Sinai School of Medicine, New York, New York, USA
    PLoS Pathog 3:1414-21. 2007
    ..Together, these data show that a single amino acid substitution in PB1-F2 can result in increased viral pathogenicity and could be one of the factors contributing to the high lethality seen with the 1918 pandemic virus...