Eva Scheuring Vanamee

Summary

Affiliation: Mount Sinai School of Medicine
Country: USA

Publications

  1. ncbi Crystallization of restriction endonuclease SfiI in complex with DNA
    Hector Viadiu
    Department of Physiology and Biophysics, Mount Sinai School of Medicine, New York, NY 10029, USA
    Acta Crystallogr D Biol Crystallogr 59:1493-5. 2003
  2. ncbi An EM view of the FokI synaptic complex by single particle analysis
    Eva Scheuring Vanamee
    Department of Structural and Chemical Biology, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Mol Biol 370:207-12. 2007
  3. ncbi A view of consecutive binding events from structures of tetrameric endonuclease SfiI bound to DNA
    Eva Scheuring Vanamee
    Structural Biology Program, Department of Physiology and Biophysics, Mount Sinai School of Medicine, New York, NY 10029, USA
    EMBO J 24:4198-208. 2005
  4. ncbi Asymmetric DNA recognition by the OkrAI endonuclease, an isoschizomer of BamHI
    Eva Scheuring Vanamee
    Department of Structural and Chemical Biology, Mount Sinai School of Medicine, New York, NY 10029, USA
    Nucleic Acids Res 39:712-9. 2011
  5. ncbi Glucocorticoid receptor-like Zn(Cys)4 motifs in BslI restriction endonuclease
    Eva Scheuring Vanamee
    Structural Biology Program, Department of Physiology and Biophysics, Mount Sinai School of Medicine, 1425 Madison Avenue, New York, NY 10029, USA
    J Mol Biol 334:595-603. 2003
  6. ncbi Crystal structure of BstYI at 1.85A resolution: a thermophilic restriction endonuclease with overlapping specificities to BamHI and BglII
    Sharon A Townson
    Structural Biology Program, Department of Physiology and Biophysics, Mount Sinai School of Medicine, 1425 Madison Avenue, New York, NY 10029, USA
    J Mol Biol 338:725-33. 2004

Collaborators

Detail Information

Publications6

  1. ncbi Crystallization of restriction endonuclease SfiI in complex with DNA
    Hector Viadiu
    Department of Physiology and Biophysics, Mount Sinai School of Medicine, New York, NY 10029, USA
    Acta Crystallogr D Biol Crystallogr 59:1493-5. 2003
    ..5, c = 419.6 A, when the selenomethionyl (SeMet) derivative of the enzyme is co-crystallized with the same DNA. Phase information is currently being derived from this SeMet SfiI-DNA complex...
  2. ncbi An EM view of the FokI synaptic complex by single particle analysis
    Eva Scheuring Vanamee
    Department of Structural and Chemical Biology, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Mol Biol 370:207-12. 2007
    ..Our electron microscopy (EM) model provides new insights into the activation mechanism of FokI and how non-specific cleavage is avoided...
  3. ncbi A view of consecutive binding events from structures of tetrameric endonuclease SfiI bound to DNA
    Eva Scheuring Vanamee
    Structural Biology Program, Department of Physiology and Biophysics, Mount Sinai School of Medicine, New York, NY 10029, USA
    EMBO J 24:4198-208. 2005
    ..We show that even though SfiI is a tetramer and BglI is a dimer, and there is little sequence similarity between the two enzymes, their modes of DNA recognition are unusually similar...
  4. ncbi Asymmetric DNA recognition by the OkrAI endonuclease, an isoschizomer of BamHI
    Eva Scheuring Vanamee
    Department of Structural and Chemical Biology, Mount Sinai School of Medicine, New York, NY 10029, USA
    Nucleic Acids Res 39:712-9. 2011
    ..Together, the OkrAI and BamHI structures offer a rare opportunity to compare two restriction enzymes that work on exactly the same DNA substrate...
  5. ncbi Glucocorticoid receptor-like Zn(Cys)4 motifs in BslI restriction endonuclease
    Eva Scheuring Vanamee
    Structural Biology Program, Department of Physiology and Biophysics, Mount Sinai School of Medicine, 1425 Madison Avenue, New York, NY 10029, USA
    J Mol Biol 334:595-603. 2003
    ..On the basis of these data, we propose a role for the BslI Zn motifs in protein-DNA as well as protein-protein interactions...
  6. ncbi Crystal structure of BstYI at 1.85A resolution: a thermophilic restriction endonuclease with overlapping specificities to BamHI and BglII
    Sharon A Townson
    Structural Biology Program, Department of Physiology and Biophysics, Mount Sinai School of Medicine, 1425 Madison Avenue, New York, NY 10029, USA
    J Mol Biol 338:725-33. 2004
    ..This arm substructure may underlie the thermostability of BstYI. We identify putative DNA recognition residues and speculate as to how this enzyme achieves a "relaxed" DNA specificity...