Research Topics
Species | Christa S MerzdorfSummaryAffiliation: Montana State University Country: USA Publications
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Publications
Emerging roles for zic genes in early developmentChrista S Merzdorf
Department of Cell Biology and Neuroscience, Montana State University, Bozeman, Montana
Dev Dyn 236:922-40. 2007..Despite significant progress, however, much remains to be learned regarding the mechanisms through which zic genes exert their function in a variety of different contexts...
Expression of the zic1, zic2, zic3, and zic4 genes in early chick embryosAriel R McMahon
Department of Cell Biology and Neuroscience, Montana State University, Bozeman, MT 59717, USA
BMC Res Notes 3:167. 2010..Since little is known about zic gene expression in chick embryos, we have characterized the expression patterns of the zic1, zic2, zic3, and zic4 (zic1-4) genes during neurulation and somitogenesis...
A microarray screen for direct targets of Zic1 identifies an aquaporin gene, aqp-3b, expressed in the neural foldsE Jean Cornish
Department of Cell Biology and Neuroscience, Montana State University, Bozeman, Montana 59717, USA
Dev Dyn 238:1179-94. 2009..Aqp-3b may also be involved in neural tube closure, since mammalian Aqp-3 promotes cell migration and proliferation...
The Xfeb gene is directly upregulated by Zic1 during early neural developmentShuzhao Li
Department of Cell Biology and Neuroscience, Montana State University, Bozeman, Montana, USA
Dev Dyn 235:2817-27. 2006..Xfeb represses the hindbrain gene hoxB1 and the anterior neural gene otx2, suggesting that Xfeb is involved in regionalizing the neural plate, possibly by ensuring a posterior expression limit for otx2...
The zic1 gene is expressed in chick somites but not in migratory neural crestLisa S Sun Rhodes
Department of Cell Biology and Neuroscience, Montana State University, 513 Leon Johnson Hall, Bozeman, MT 59717, USA
Gene Expr Patterns 6:539-45. 2006..Double-label experiments showed that cells expressing zic1 are not labeled by the HNK-1 antibody specific for migratory neural crest cells. Thus, migrating neural crest cells do not express zic1...
The zic1 gene is an activator of Wnt signalingChrista S Merzdorf
Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, USA
Int J Dev Biol 50:611-7. 2006..Together, our data suggest that zic1 is an upstream regulator of several wnt genes and that the regulatory relationships between opa, wingless and engrailed seen in Drosophila are also present in vertebrates...
