V Prakash Reddy

Summary

Affiliation: Missouri University of Science and Technology
Country: USA

Publications

  1. ncbi Oxidative stress in diabetes and Alzheimer's disease
    V Prakash Reddy
    Department of Chemistry, Missouri University of Science and Technology, Rolla, MO 65409, USA
    J Alzheimers Dis 16:763-74. 2009
  2. ncbi NMR studies of zinc, copper, and iron binding to histidine, the principal metal ion complexing site of amyloid-beta peptide
    Nanditha G Nair
    Department of Chemistry, Missouri University of Science and Technology, Rolla, MO 65409, USA
    J Alzheimers Dis 20:57-66. 2010
  3. ncbi Carnosine: a versatile antioxidant and antiglycating agent
    V Prakash Reddy
    Department of Chemistry, University of Missouri Rolla, Rolla, MO 65409, USA
    Sci Aging Knowledge Environ 2005:pe12. 2005
  4. ncbi Inhibitors of the Maillard reaction and AGE breakers as therapeutics for multiple diseases
    V Prakash Reddy
    Department of Chemistry, University of Missouri Rolla, Rolla, MO 65409, USA
    Drug Discov Today 11:646-54. 2006
  5. ncbi Novel purine-based fluoroaryl-1,2,3-triazoles as neuroprotecting agents: synthesis, neuronal cell culture investigations, and CDK5 docking studies
    Nanditha Nair
    Department of Chemistry, Missouri University of Science and Technology, Rolla, MO 65409, United States
    Bioorg Med Chem Lett 21:3957-61. 2011
  6. ncbi Transition metal ion binding studies of carnosine and histidine: biologically relevant antioxidants
    Stephanie Velez
    Department of Chemistry, Missouri University of Science and Technology, Rolla, MO 65409, USA
    Colloids Surf B Biointerfaces 66:291-4. 2008

Collaborators

Detail Information

Publications6

  1. ncbi Oxidative stress in diabetes and Alzheimer's disease
    V Prakash Reddy
    Department of Chemistry, Missouri University of Science and Technology, Rolla, MO 65409, USA
    J Alzheimers Dis 16:763-74. 2009
    ....
  2. ncbi NMR studies of zinc, copper, and iron binding to histidine, the principal metal ion complexing site of amyloid-beta peptide
    Nanditha G Nair
    Department of Chemistry, Missouri University of Science and Technology, Rolla, MO 65409, USA
    J Alzheimers Dis 20:57-66. 2010
    ..From these studies, we suggest that Abeta-chelated Zn(II) is readily displaced by Cu(II) and Fe(III) ions and leads to a propagation of oxidative stress...
  3. ncbi Carnosine: a versatile antioxidant and antiglycating agent
    V Prakash Reddy
    Department of Chemistry, University of Missouri Rolla, Rolla, MO 65409, USA
    Sci Aging Knowledge Environ 2005:pe12. 2005
    ..AGEs are known contributors to the pathology of Alzheimer's disease, and carnosine therefore merits serious attention as a possible therapeutic agent...
  4. ncbi Inhibitors of the Maillard reaction and AGE breakers as therapeutics for multiple diseases
    V Prakash Reddy
    Department of Chemistry, University of Missouri Rolla, Rolla, MO 65409, USA
    Drug Discov Today 11:646-54. 2006
    ....
  5. ncbi Novel purine-based fluoroaryl-1,2,3-triazoles as neuroprotecting agents: synthesis, neuronal cell culture investigations, and CDK5 docking studies
    Nanditha Nair
    Department of Chemistry, Missouri University of Science and Technology, Rolla, MO 65409, United States
    Bioorg Med Chem Lett 21:3957-61. 2011
    ..These combined experimental and theoretical studies support the involvement of CDK5/p25 in the neuronal cell cycle re-entry...
  6. ncbi Transition metal ion binding studies of carnosine and histidine: biologically relevant antioxidants
    Stephanie Velez
    Department of Chemistry, Missouri University of Science and Technology, Rolla, MO 65409, USA
    Colloids Surf B Biointerfaces 66:291-4. 2008
    ..84+/-0.18, were found to be 71 and 1.1M(-1), respectively. The unexpectedly lower binding constant values of carnosine show the relatively minor role of the transition metal ion chelation in their antioxidant abilities...