Research Topics
| J CourcelleSummaryAffiliation: Mississippi State University Country: USA Publications
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Detail Information
Publications
DNA damage-induced replication fork regression and processing in Escherichia coliJustin Courcelle
Department of Biological Sciences, Box GY, Mississippi State University, Mississippi State, MS 39762, USA
Science 299:1064-7. 2003..We propose that fork regression allows repair enzymes to gain access to the replication-blocking lesion, allowing processive replication to resume once the blocking lesion is removed...- When replication travels on damaged templates: bumps and blocks in the roadJustin Courcelle
Department of Biological Sciences, Box GY, Mississippi State University, Mississippi State, MS 39762, USA
Res Microbiol 155:231-7. 2004.... - Comparative gene expression profiles following UV exposure in wild-type and SOS-deficient Escherichia coliJ Courcelle
Department of Biochemistry, Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA
Genetics 158:41-64. 2001..These newly identified UV-responsive genes are discussed with respect to their possible roles in cellular recovery following exposure to UV irradiation... - Therefore, what are recombination proteins there for?J Courcelle
Department of Biological Sciences Mississippi State University, 39762, USA
Bioessays 23:463-70. 2001.... - Participation of recombination proteins in rescue of arrested replication forks in UV-irradiated Escherichia coli need not involve recombinationJ Courcelle
Department of Biological Sciences, Mississippi State University, P O Box GY, Mississippi State, MS 39762 5759, USA
Proc Natl Acad Sci U S A 98:8196-202. 2001.... - RecA-dependent recovery of arrested DNA replication forksJustin Courcelle
Department of Biological Sciences, Box GY, Mississippi State University, Mississippi State, Mississippi 39762, USA
Annu Rev Genet 37:611-46. 2003..In this review, we examine the significant experimental approaches that have led to our current understanding of the RecA-mediated processes that restore replication following encounters with DNA damage... - RecQ and RecJ process blocked replication forks prior to the resumption of replication in UV-irradiated Escherichia coliJ Courcelle
Biological Sciences, Stanford University, CA 94305, USA
Mol Gen Genet 262:543-51. 1999.... - recF and recR are required for the resumption of replication at DNA replication forks in Escherichia coliJ Courcelle
Department of Biological Sciences, Stanford University, CA 94305 5020, USA
Proc Natl Acad Sci U S A 94:3714-9. 1997..Current biochemical and genetic data on the conditions under which recF-mediated recombination occurs suggest that the recombinational intermediate also may mimic the structure of a disrupted replication fork... - Recovery of DNA replication in UV-irradiated Escherichia coli requires both excision repair and recF protein functionJ Courcelle
Department of Biological Sciences, Stanford University, Stanford, California 94305, USA
J Bacteriol 181:916-22. 1999.... - Requirement for uracil-DNA glycosylase during the transition to late-phase cytomegalovirus DNA replicationC T Courcelle
Department of Microbiology and Immunology, Stanford University, Stanford, California 94305, USA
J Virol 75:7592-601. 2001..The process of uracil incorporation and excision may introduce strand breaks to facilitate the transition from early-phase replication to late-phase amplification... - Inactivation of the DnaB helicase leads to the collapse and degradation of the replication fork: a comparison to UV-induced arrestJerilyn J Belle
Department of Biological Sciences, Mississippi State University, Mississippi State, Mississippi 39762, USA
J Bacteriol 189:5452-62. 2007..We discuss these observations in relation to potential models for both UV-induced and DnaB(Ts)-mediated replication inhibition... - Structural conservation of RecF and Rad50: implications for DNA recognition and RecF functionOlga Koroleva
Edward A Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St Louis, MO 63104, USA
EMBO J 26:867-77. 2007..The RecF structure, mutagenesis of conserved motifs and ATP-dependent dimerization of RecF are discussed with respect to its role in promoting presynaptic complex formation at DNA damage sites... - RuvABC is required to resolve holliday junctions that accumulate following replication on damaged templates in Escherichia coliJanet R Donaldson
Department of Biology, Portland State University, Portland, Oregon 97207, USA
J Biol Chem 281:28811-21. 2006..A model is proposed in which RuvABC is required to resolve junctions that arise during the repair of a subset of nonarresting lesions after replication has passed through the template... - Monitoring DNA replication following UV-induced damage in Escherichia coliCharmain T Courcelle
Department of Biology, Portland State University, Oregon, USA
Methods Enzymol 409:425-41. 2006..This chapter describes three techniques that can be used to monitor the progression, degradation, and structural properties of replication forks following UV-induced DNA damage in Escherichia coli... - Nascent DNA processing by RecJ favors lesion repair over translesion synthesis at arrested replication forks in Escherichia coliCharmain T Courcelle
Department of Biology, Portland State University, Box 751, Portland, OR 97207 0751, USA
Proc Natl Acad Sci U S A 103:9154-9. 2006..In the absence of nascent DNA processing, polymerase V can synthesize past the lesion to prevent lethality, although this occurs with slower kinetics and a higher frequency of mutagenesis... - Nucleotide excision repair or polymerase V-mediated lesion bypass can act to restore UV-arrested replication forks in Escherichia coliCharmain T Courcelle
Department of Biology, P O Box 751, Portland State University, Portland, OR 97207 0751, USA
J Bacteriol 187:6953-61. 2005..We discuss a model in which cells first use DNA repair to process replication-arresting UV lesions before resorting to mutagenic pathways such as translesion DNA synthesis to bypass these impediments to replication progression... - Recs preventing wrecksJustin Courcelle
Portland State University, Department of Biology, P O Box 751, Portland, OR 97207 0751, USA
Mutat Res 577:217-27. 2005.... - RuvAB and RecG are not essential for the recovery of DNA synthesis following UV-induced DNA damage in Escherichia coliJanet R Donaldson
Department of Biological Sciences, Mississippi State University, Mississippi State, Mississippi 39762, USA
Genetics 166:1631-40. 2004..The data presented here indicate that RecG- or RuvAB-catalyzed fork regression is not essential for DNA synthesis to resume following arrest by UV-induced DNA damage in vivo... - RecO acts with RecF and RecR to protect and maintain replication forks blocked by UV-induced DNA damage in Escherichia coliKin Hoe Chow
Department of Biological Science, Mississippi State University, Mississippi State, Mississippi 39762, USA
J Biol Chem 279:3492-6. 2004.... - RecBCD and RecJ/RecQ initiate DNA degradation on distinct substrates in UV-irradiated Escherichia coliKin Hoe Chow
Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA
Radiat Res 168:499-506. 2007..In addition, they demonstrate that RecBCD initiates degradation at a site(s) other than the arrested replication fork directly...