Research Topics
Species | B J MaronSummaryAffiliation: Minneapolis Heart Institute Foundation Country: USA Publications
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Detail Information
Publications
Prevalence, clinical significance, and natural history of left ventricular apical aneurysms in hypertrophic cardiomyopathyMartin S Maron
Division of Cardiology, Hypertrophic Cardiomyopathy Center, Tufts Medical Center, Boston, Massachussetts 02111, USA
Circulation 118:1541-9. 2008..This study reports the prevalence, morphology, clinical course, and management of an underrecognized subgroup of HCM patients with left ventricular apical aneurysms...
Double or compound sarcomere mutations in hypertrophic cardiomyopathy: a potential link to sudden death in the absence of conventional risk factorsBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota 55407, USA
Heart Rhythm 9:57-63. 2012..Therefore, additional genetic risk markers that reliably determine which patients are predisposed to sudden death are needed...
The heart of trained athletes: cardiac remodeling and the risks of sports, including sudden deathBarry J Maron
The Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, 920 East 28th St, Suite 60, Minneapolis, MN 55407, USA
Circulation 114:1633-44. 2006
The 50-year history, controversy, and clinical implications of left ventricular outflow tract obstruction in hypertrophic cardiomyopathy from idiopathic hypertrophic subaortic stenosis to hypertrophic cardiomyopathy: from idiopathic hypertrophic subaorticBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota 55407, USA
J Am Coll Cardiol 54:191-200. 2009....
Ten common questions about hypertrophic cardiomyopathy...and misconceptionsBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota 55407, USA
Cardiol Rev 13:59-60. 2005
Images in cardiovascular medicine. Diagnostic utility of cardiac magnetic resonance imaging in monozygotic twins with hypertrophic cardiomyopathy and identical pattern of left ventricular hypertrophyBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, 920 East 28th Street, Minneapolis, MN 55407, USA
Circulation 115:e627-8. 2007
Commotio cordis and the epidemiology of sudden death in competitive lacrosseBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, MN 55407, USA
Pediatrics 124:966-71. 2009..Athletic field risks associated with blunt, nonpenetrating chest blows (commotio cordis) are receiving increasing attention, but the epidemiology of these events is incomplete...
Proposal for contemporary screening strategies in families with hypertrophic cardiomyopathyBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota, USA
J Am Coll Cardiol 44:2125-32. 2004..Of note, recent developments in laboratory DNA-based diagnosis for HCM could potentially avoid the necessity for serial echocardiography in many such relatives...
The case for surgery in obstructive hypertrophic cardiomyopathyBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota 55407, USA
J Am Coll Cardiol 44:2044-53. 2004....
Hypertrophic cardiomyopathy in childhoodBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, 920 East 28th Street, Suite 60, Minneapolis, MN 55407, USA
Pediatr Clin North Am 51:1305-46. 2004..Consequently, it is timely to place perspective and clarify many of these relevant clinical issues, and profile the rapidly evolving concepts regarding HCM, especially as they may impact on this disease in childhood...
Prevalence of hypertrophic cardiomyopathy in a population-based sample of American Indians aged 51 to 77 years (the Strong Heart Study)Barry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota 55407, USA
Am J Cardiol 93:1510-4. 2004..This prevalence was similar to that reported in other general populations comprised of younger subjects of other races, offering evidence that HC is a relatively common genetic disease with widespread occurrence within the United States...
Usefulness of B-type natriuretic peptide assay in the assessment of symptomatic state in hypertrophic cardiomyopathyBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, and University of Minnesota, Minneapolis, MN 55407, USA
Circulation 109:984-9. 2004..Plasma B-type natriuretic peptide (BNP) has been used widely as an objective marker for heart failure severity and outcome, predominantly in coronary heart disease with ventricular dilatation and systolic dysfunction...
Distinguishing hypertrophic cardiomyopathy from athlete's heart physiological remodelling: clinical significance, diagnostic strategies and implications for preparticipation screeningB J Maron
Minneapolis Heart Institute Foundation, 920 East 28th Street, Suite 620, Minneapolis, MN 55407, USA
Br J Sports Med 43:649-56. 2009..Consensus criteria and recommendations for eligibility and disqualification of athletes with HCM (and other cardiovascular abnormalities) have proved useful to the practising community...
Extreme hypertrophic cardiomyopathyB J Maron
Heart 90:24. 2004
Comparison of U.S. and Italian experiences with sudden cardiac deaths in young competitive athletes and implications for preparticipation screening strategiesBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota, USA
Am J Cardiol 104:276-80. 2009..These data do not support a lower mortality rate associated with preparticipation screening programs involving routine electrocardiography and examinations by specially trained personnel...
Long-term survival after cardiac arrest in hypertrophic cardiomyopathyBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota 55407, USA
Heart Rhythm 6:993-7. 2009..However, outcome over extended time periods after major arrhythmic events is unresolved in such HCM patients...
Circadian patterns in the occurrence of malignant ventricular tachyarrhythmias triggering defibrillator interventions in patients with hypertrophic cardiomyopathyBarry J Maron
Hypertrophic Cardiomyopathy Center of the Minneapolis Heart Institute Foundation, Minneapolis, Minnesota 55407, USA
Heart Rhythm 6:599-602. 2009..However, little is known about the circadian pattern of life-threatening arrhythmias in HCM in the contemporary era of the implantable cardioverter-defibrillator (ICD)...
Controversies in cardiovascular medicine. Surgical myectomy remains the primary treatment option for severely symptomatic patients with obstructive hypertrophic cardiomyopathyBarry J Maron
Minneapolis Heart Institute Foundation, 920 E 28th St, Ste 60, Minneapolis, MN 55407, USA
Circulation 116:196-206; discussion 206. 2007
Implantable cardioverter-defibrillators and prevention of sudden cardiac death in hypertrophic cardiomyopathyBarry J Maron
Hypertrophic Cardiomyopathy Center of the Minneapolis Heart Institute Foundation, Minneapolis, Minnesota 55407, USA
JAMA 298:405-12. 2007..However, the effectiveness and appropriate selection of patients for this therapy is incompletely resolved...
Hypertrophic cardiomyopathy and other causes of sudden cardiac death in young competitive athletes, with considerations for preparticipation screening and criteria for disqualificationBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, MN 55407, USA
Cardiol Clin 25:399-414, vi. 2007..Removal from intense training and competition is recommended for athletes with HCM, some of whom may ultimately be judged to be at unacceptably high risk for sudden death and eligible for prophylactic defibrillator implantation...
Historical observation on commotio cordisBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota 55407, USA
Heart Rhythm 3:605-6. 2006
Sudden cardiac arrest in hypertrophic cardiomyopathy in the absence of conventional criteria for high risk statusBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota, USA
Am J Cardiol 101:544-7. 2008....
Death in a young athlete due to commotio cordis despite prompt external defibrillationBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota 55407, USA
Heart Rhythm 2:991-3. 2005
Implantable defibrillators and prevention of sudden death in hypertrophic cardiomyopathyBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota 55407, USA
J Cardiovasc Electrophysiol 19:1118-26. 2008..Therefore, a single marker of high risk may represent sufficient evidence to justify the recommendation for a prophylactic ICD in selected patients with HCM...
It is not prudent to allow all athletes with implantable-cardioverter defibrillators to participate in all sportsBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota, USA
Heart Rhythm 5:864-6. 2008
The first patient clinically diagnosed with hypertrophic cardiomyopathyBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, MN, USA
Am J Cardiol 102:1418-20. 2008....
Sudden deaths in young competitive athletes: analysis of 1866 deaths in the United States, 1980-2006Barry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation and Abbott Northwestern Hospital, Minneapolis, Minn, USA
Circulation 119:1085-92. 2009..Sudden deaths in young competitive athletes are highly visible events with substantial impact on the physician and lay communities. However, the magnitude of this public health issue has become a source of controversy...
Clinical outcome and phenotypic expression in LAMP2 cardiomyopathyBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, 920 E 28th St, Ste 620, Minneapolis, MN 55407, USA
JAMA 301:1253-9. 2009..However, the natural history and phenotypic expression of this newly recognized disease is incompletely resolved and its identification may have important clinical implications...
[Prevention of sudden death in hypertrophic cardiomyopathy (HCM ): implanted defibrillators in HCM]Barry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, MN 55407, USA
Zhonghua Xin Xue Guan Bing Za Zhi 37:297-302. 2009..A single marker of high risk can be sufficient evidence to justify the recommendation for a prophylactic ICD in selected patients with HCM...
Implications of hypertrophic cardiomyopathy transmitted by sperm donationBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation and Abbott Northwestern Hospital, Minneapolis, Minnesota 55407, USA
JAMA 302:1681-4. 2009..The unintended consequence in which genetic diseases are unwittingly transmitted to offspring is an underrecognized public health issue not previously prioritized by US Food and Drug Administration guidelines...
The young competitive athlete with cardiovascular abnormalities: causes of sudden death, detection by preparticipation screening, and standards for disqualificationBarry J Maron
Cardiovascular Research Division, Minneapolis Heart Institute Foundation, Minneapolis, MN 55407, USA
Card Electrophysiol Rev 6:100-3. 2002
Two husbands--one disease: the broad clinical spectrum of hypertrophic cardiomyopathyBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota 55407, USA
Am J Cardiol 89:899-900. 2002
Hypertrophic cardiomyopathy: practical steps for preventing sudden deathBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, MN, 55407, USA
Phys Sportsmed 30:19-24. 2002..Molecular detection methods for known defective genes in HCM have not yet become routine clinical tools. Athletes with unequivocal HCM should not participate in competitive sports, except for perhaps some low-intensity ones...
Hypertrophic cardiomyopathy: a systematic reviewBarry J Maron
Minneapolis Heart Institute Foundation, 920 E 28th St, Suite 60, Minneapolis, MN 55407, USA
JAMA 287:1308-20. 2002....
Clinical profile and spectrum of commotio cordisBarry J Maron
Minneapolis Heart Institute Foundation, 920 E 28th St, Suite 60, Minneapolis, MN 55407, USA
JAMA 287:1142-6. 2002..Although blunt, nonpenetrating chest blows causing sudden cardiac death (commotio cordis) are often associated with competitive sports, dangers implicit in such blows can extend into many other life activities...
Controversies in cardiovascular medicine. Benefits of surgery in obstructive hypertrophic cardiomyopathy: bring septal myectomy back for European patientsBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, 920 E 28th Street, Minneapolis, MN 55407, USA
Eur Heart J 32:1055-8. 2011..It is our aspiration that this discussion will generate reconsideration and resurgence of interest in surgical septal myectomy as a treatment option for severely symptomatic obstructive HCM patients within Europe...
Clinical profile of stroke in 900 patients with hypertrophic cardiomyopathyBarry J Maron
Minneapolis Heart Institute Foundation, Minneapolis, Minnesota 55407, USA
J Am Coll Cardiol 39:301-7. 2002..We sought to assess the occurrence and clinical significance of stroke and peripheral arterial embolizations at non-central nervous system sites in a large, community-based cohort with hypertrophic cardiomyopathy (HCM)...
Development of left ventricular hypertrophy in adults in hypertrophic cardiomyopathy caused by cardiac myosin-binding protein C gene mutationsB J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minnesota 55407, USA
J Am Coll Cardiol 38:315-21. 2001..We sought to determine whether the development of left ventricular hypertrophy (LVH) can be demonstrated during adulthood in genetically affected relatives with hypertrophic cardiomyopathy (HCM)...
"Speckled" ventricular septum in hypertrophic cardiomyopathy revisited after 30 yearsBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota, USA
Am J Cardiol 107:1862-3. 2011..In conclusion, myocardial fibrosis in patients with hypertrophic cardiomyopathy is most reliably identified using contrast-enhanced cardiovascular magnetic resonance imaging...
Onset of apical hypertrophic cardiomyopathy in adulthoodBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation at Abbott Northwestern Hospital, Minneapolis, Minnesota
Am J Cardiol 108:1783-7. 2011..Electrocardiographic repolarization abnormalities can predict the future development of apical LV hypertrophy in adults with HC...
Images in cardiovascular medicine. Hypertrophic cardiomyopathy in monozygotic twinsBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation Minneapolis, Minn 55407, USA
Circulation 105:2229. 2002
Risk stratification and role of implantable defibrillators for prevention of sudden death in patients with hypertrophic cardiomyopathyBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, MN 55407, USA
Circ J 74:2271-82. 2010..Indeed, prevention of SCD has now become a new paradigm in the management of HCM...
Profound left ventricular remodeling associated with LAMP2 cardiomyopathyBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota, USA
Am J Cardiol 106:1194-6. 2010..e. marked wall thinning), chamber dilatation, and severe systolic dysfunction, all of which are associated with widespread transmural scarring...
Sudden death in young athletesBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, MN 55407, USA
N Engl J Med 349:1064-75. 2003
Clinical course of hypertrophic cardiomyopathy with survival to advanced ageBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, 920 E 28th Street, Suite 60, Minneapolis, MN 55407, USA
J Am Coll Cardiol 42:882-8. 2003..This study was designed to clarify and resolve the clinical profile of older patients with hypertrophic cardiomyopathy (HCM)...
Can sudden cardiac death be prevented?Barry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, MN 55407, USA
Cardiovasc Pathol 19:329-35. 2010..Indeed, prevention of sudden death has now become an integral, albeit challenging, component of overall hypertrophic cardiomyopathy management...
Relation of left ventricular thickness to age and gender in hypertrophic cardiomyopathyBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota 55407, USA
Am J Cardiol 91:1195-8. 2003....
Relationship of race to sudden cardiac death in competitive athletes with hypertrophic cardiomyopathyBarry J Maron
Minneapolis Heart Institute Foundation, 920 East 28th Street, Suite 60, Minneapolis, MN 55407, USA
J Am Coll Cardiol 41:974-80. 2003..The goal of this study was to determine the impact of race on identification of hypertrophic cardiomyopathy (HCM)...
Sudden death in hypertrophic cardiomyopathyBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, MN, 55407, USA
J Cardiovasc Transl Res 2:368-80. 2009..Prevention of SD is now an integral, albeit challenging, component of HCM management...
Relation of extreme left ventricular hypertrophy to age in hypertrophic cardiomyopathyBarry J Maron
Minneapolis Heart Institute Foundation, Minneapolis, Minnesota 55407, USA
Am J Cardiol 91:626-8. 2003
Novel hypertrophic cardiomyopathy phenotype: segmental hypertrophy isolated to the posterobasal left ventricular free wallBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minnesota, USA
Am J Cardiol 106:750-2. 2010....
Cardiology patient pages. Hypertrophic cardiomyopathyBarry J Maron
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, Minn 55407, USA
Circulation 106:2419-21. 2002
Primary prevention of sudden death as a novel treatment strategy in hypertrophic cardiomyopathyBarry J Maron
The Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, 920 E 28th St, Suite 60, Minneapolis, Minn 55407, USA
Circulation 107:2872-5. 2003
Global epidemiology and demographics of commotio cordisBarry J Maron
The Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota 55407, USA
Heart Rhythm 8:1969-71. 2011..However, with enhanced public awareness, commotio cordis has been increasingly recognized internationally as a cause of cardiac arrest and sudden death due to blunt nonpenetrating chest blows...
Clinical course of hypertrophic cardiomyopathy in a regional United States cohortB J Maron
Cardiovascular Research Division, Minneapolis Heart Institute Foundation, School of Public Health, University of Minnesota, 55407, USA
JAMA 281:650-5. 1999..Hypertrophic cardiomyopathy (HCM) has been regarded as a disease that causes substantial disability, with annual mortality rates of up to 6%, based largely on reports from tertiary referral centers...
Extended septal myectomy for hypertrophic obstructive cardiomyopathy with anomalous mitral papillary muscles or chordaeKenji Minakata
Division of Cardiovascular Surgery, Mayo Clinic, Rochester, Minn, USA
J Thorac Cardiovasc Surg 127:481-9. 2004....
Epidemiology of hypertrophic cardiomyopathy-related death: revisited in a large non-referral-based patient populationB J Maron
Minneapolis Heart Institute Foundation, Minneapolis, MN 55407, USA
Circulation 102:858-64. 2000..These data emanated from tertiary HCM centers with highly selected referral patterns skewed toward high-risk patients...
Clinical profile of commotio cordis: an under appreciated cause of sudden death in the young during sports and other activitiesB J Maron
Minneapolis Heart Institute Foundation, Minnesota 55407, USA
J Cardiovasc Electrophysiol 10:114-20. 1999....
Recommendations and considerations related to preparticipation screening for cardiovascular abnormalities in competitive athletes: 2007 update: a scientific statement from the American Heart Association Council on Nutrition, Physical Activity, and MetabolBarry J Maron
Minneapolis Heart Institute Foundation, USA
Circulation 115:1643-455. 2007
Relation of electrocardiographic patterns to phenotypic expression and clinical outcome in hypertrophic cardiomyopathyJulia V Montgomery
The Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, MN, USA
Am J Cardiol 96:270-5. 2005..Diverse ECG patterns, consistent with heterogeneous expression of this disease, did not predict HC-related death. Scalar electrocardiography has selective but limited power in routine clinical assessments of patients with HC...
Ventricular arrhythmias, sudden death, and prevention in patients with hypertrophic cardiomyopathyB J Maron
Minneapolis Heart Institute Foundation, 920 E 28th Street, Suite 40, Minneapolis, MN 55407, USA
Curr Cardiol Rep 2:522-8. 2000....
Comparison of surgical septal myectomy and alcohol septal ablation with cardiac magnetic resonance imaging in patients with hypertrophic obstructive cardiomyopathyUma S Valeti
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA
J Am Coll Cardiol 49:350-7. 2007..This study sought to describe the acute morphologic differences that result from septal myectomy and alcohol septal ablation using cardiac magnetic resonance (CMR) imaging...
Efficacy of implantable cardioverter-defibrillators for the prevention of sudden death in patients with hypertrophic cardiomyopathyB J Maron
Minneapolis Heart Institute Foundation, MN 55407, USA
N Engl J Med 342:365-73. 2000..Hypertrophic cardiomyopathy is a genetic disease associated with a risk of ventricular tachyarrhythmias and sudden death, especially in young patients...
Risk stratification and prevention of sudden death in hypertrophic cardiomyopathyBarry J Maron
Minneapolis Heart Institute Foundation, Minneapolis, Minnesota 55407, USA
Cardiol Rev 10:173-81. 2002....
Implications of arrhythmias and prevention of sudden death in hypertrophic cardiomyopathyA Selcuk Adabag
Division of Cardiology, Veterans Affairs Medical Center, Minneapolis, MN 55417, USA
Ann Noninvasive Electrocardiol 12:171-80. 2007
Acute and reversible cardiomyopathy provoked by stress in women from the United StatesScott W Sharkey
Minneapolis Heart Institute Foundation, Minneapolis, Minn 55407, USA
Circulation 111:472-9. 2005..This condition is characterized by a distinctive form of systolic dysfunction that predominantly affects the distal LV chamber and a favorable outcome with appropriate medical therapy...
Spectrum and prognostic significance of arrhythmias on ambulatory Holter electrocardiogram in hypertrophic cardiomyopathyA Selcuk Adabag
Division of Cardiology, and Geriatric Research Education and Clinical Center, Veterans Affairs Medical Center, Minneapolis, Minnesota, USA
J Am Coll Cardiol 45:697-704. 2005..The goal of this study was to assemble a profile and assess the significance of arrhythmias in a nontertiary-based hypertrophic cardiomyopathy (HCM) cohort...
Assessment of permanent dual-chamber pacing as a treatment for drug-refractory symptomatic patients with obstructive hypertrophic cardiomyopathy. A randomized, double-blind, crossover study (M-PATHY)B J Maron
Minneapolis Heart Institute Foundation, Minneapolis, MN 55407, USA
Circulation 99:2927-33. 1999..Dual-chamber pacing (DDD) has been proposed as a treatment alternative to surgery for severely symptomatic patients with obstructive hypertrophic cardiomyopathy (HCM), based largely on uncontrolled studies...
Prevalence, clinical profile, and significance of left ventricular remodeling in the end-stage phase of hypertrophic cardiomyopathyKevin M Harris
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, 920 E 28th St, Suite 60, Minneapolis, Minnesota 55407, USA
Circulation 114:216-25. 2006..ES is an unfavorable complication (mortality rate 11% per year) and a sudden death risk factor; it requires vigilance to permit timely recognition and the necessity for defibrillator implantation and heart transplantation...
Hypertrophic cardiomyopathy phenotype revisited after 50 years with cardiovascular magnetic resonanceMartin S Maron
Hypertrophic Cardiomyopathy Center, Division of Cardiology, Tufts Medical Center, Boston, Massachusetts 02111, USA
J Am Coll Cardiol 54:220-8. 2009....
Significance and relation between magnitude of left ventricular hypertrophy and heart failure symptoms in hypertrophic cardiomyopathyMartin S Maron
Hypertrophic Cardiomyopathy Center, Division of Cardiology, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
Am J Cardiol 95:1329-33. 2005..In conclusion, no direct relation was evident between symptoms of heart failure and magnitude of LV wall thickness, with implications for the natural history of HC...
Brief communication: Cardiovascular screening practices of major North American professional sports teamsKevin M Harris
Minneapolis Heart Institute Foundation, Minneapolis, Minnesota 55407, USA
Ann Intern Med 145:507-11. 2006..Customary preparticipation screening strategies to detect heart disease in professional athletes have not been examined systematically...
Utility of cardiac magnetic resonance imaging in the diagnosis of hypertrophic cardiomyopathyCarsten Rickers
Department of Radiology, Fairview-University Medical Center, Minneapolis, MN, USA
Circulation 112:855-61. 2005..CMR enhances the assessment of LV hypertrophy, particularly in the anterolateral LV free wall, and represents a powerful supplemental imaging test with distinct diagnostic advantages for selected HCM patients...
Role of family history of sudden death in risk stratification and prevention of sudden death with implantable defibrillators in hypertrophic cardiomyopathyJ Martijn Bos
Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA
Am J Cardiol 106:1481-6. 2010....
Determinants for clinical diagnosis of hypertrophic cardiomyopathyA Selcuk Adabag
Division of Cardiology, Veterans Affairs Medical Center, Minneapolis, Minnesota, USA
Am J Cardiol 98:1507-11. 2006..These data underscore the need for heightened awareness and clinical suspicion of HC to increase the number of diagnosed patients, including many who may be at high risk for sudden death...
Identical twins with hypertrophic cardiomyopathy and apical aneurysmAndrey G Zenovich
The Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota, USA
Am J Cardiol 97:1109. 2006..These cases demonstrate a genetic predisposition to the development of apical aneurysm, as well as overall LV morphology, in patients with HC...
Assessment of QT dispersion as a prognostic marker for sudden death in a regional nonreferred hypertrophic cardiomyopathy cohortB J Maron
Minneapolis Heart Institute Foundation, Minnesota 55407, USA
Am J Cardiol 87:114-5, A9. 2001..Therefore, QT dispersion would not appear to be useful in devising future risk stratification strategies for predicting sudden death in HC...
Epidemiology of sudden death in young, competitive athletes due to blunt traumaMathew Thomas
Minneapolis Heart Institute Foundation, 920 E 28th St, Suite 620, Minneapolis, MN 55407, USA
Pediatrics 128:e1-8. 2011..Sudden deaths of young competitive athletes are highly visible events that have a substantial effect on families and communities. Recent attention has focused predominantly on cardiovascular causes, and less on traumatic organ damage...
Effect of left ventricular outflow tract obstruction on clinical outcome in hypertrophic cardiomyopathyMartin S Maron
Division of Cardiology, Tufts-New England Medical Center, Boston, USA
N Engl J Med 348:295-303. 2003..CONCLUSIONS: In patients with hypertrophic cardiomyopathy, left ventricular outflow tract obstruction at rest is a strong, independent predictor of progression to severe symptoms of heart failure and of death...
The athlete's heart: remodeling, electrocardiogram and preparticipation screeningAntonio Pelliccia
Institute of Sports Science, Italian National Olympic Committee, Rome, Italy
Cardiol Rev 10:85-90. 2002..However, such false-positive ECGs represent a potential limitation to the efficacy of routine ECG testing in the preparticipation cardiovascular screening of large athletic populations...
Long-term clinical significance of frequent and complex ventricular tachyarrhythmias in trained athletesAlessandro Biffi
Institute of Sports Science, Department of Medicine, Italian National Olympic Committee, Rome, Italy
J Am Coll Cardiol 40:446-52. 2002..The aim of this study was to clarify the clinical relevance of ventricular tachyarrhythmias assessed by 24-h ambulatory electrocardiograms (ECG) in a large, unique, and prospectively evaluated athletic population...
Automated external defibrillator arrhythmia detection in a model of cardiac arrest due to commotio cordisMark S Link
Tufts University School of Medicine and New England Medical Center, Boston, Massachusetts 02111, USA
J Cardiovasc Electrophysiol 14:83-7. 2003..In a swine model of commotio cordis designed to be most relevant to young children, we assessed the efficacy of a commercially available AED for recognition and termination of ventricular fibrillation...
Remodeling of left ventricular hypertrophy in elite athletes after long-term deconditioningAntonio Pelliccia
Institute of Sports Science, Department of Medicine, Rome, Italy
Circulation 105:944-9. 2002..The clinical significance and long-term consequences of left ventricular (LV) hypertrophy associated with intensive athletic conditioning remain unresolved...
American College of Cardiology/European Society of Cardiology clinical expert consensus document on hypertrophic cardiomyopathy. A report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents and the European SBarry J Maron
J Am Coll Cardiol 42:1687-713. 2003
Comparison of prevalence of apical hypertrophic cardiomyopathy in Japan and the United StatesHiroaki Kitaoka
Department of Medicine and Geriatrics, Kochi Medical School, Kochi, Japan
Am J Cardiol 92:1183-6. 2003..Patients with the apical form of HC had a benign clinical course...
Hypertrophic cardiomyopathy: an important global diseaseBarry J Maron
Am J Med 116:63-5. 2004
Inter-association Task Force recommendations on emergency preparedness and management of sudden cardiac arrest in high school and college athletic programs: a consensus statementJonathan A Drezner
University of Washington, Seattle, WA 98105, USA
J Athl Train 42:143-58. 2007..This consensus statement summarizes our current understanding of SCA in young athletes, defines the necessary elements for emergency preparedness, and establishes uniform treatment protocols for the management of SCA...
Prognostic significance of left atrial size in patients with hypertrophic cardiomyopathy (from the Italian Registry for Hypertrophic Cardiomyopathy)Stefano Nistri
Istituto Superiore di Sanita, Laboratory of Epidemiology and Biostatistics, Rome, Italy
Am J Cardiol 98:960-5. 2006..LA dimension is a novel and independent marker of prognosis in HC, particularly relevant to the identification of patients at risk for death related to heart failure...
Inter-association task force recommendations on emergency preparedness and management of sudden cardiac arrest in high school and college athletic programs: a consensus statementJonathan A Drezner
University of Washington, Seattle, WA, USA
Clin J Sport Med 17:87-103. 2007..This consensus statement summarizes our current understanding of SCA in young athletes, defines the necessary elements for emergency preparedness, and establishes uniform treatment protocols for the management of SCA...
Evidence for efficacy of the Italian national pre-participation screening programme for identification of hypertrophic cardiomyopathy in competitive athletesAntonio Pelliccia
Institute of Sports Medicine and Science, Italian National Olympic Committee, Via dei Campi Sportivi, 46, 00197 Rome, Italy
Eur Heart J 27:2196-200. 2006..We assessed the diagnostic efficacy of Italian pre-participation screening programme with 12-lead ECG (in addition to history and physical examination) for identification of HCM...
Outcomes in athletes with marked ECG repolarization abnormalitiesAntonio Pelliccia
Institute of Sports Medicine and Science, Italian National Olympic Committee, Rome, Italy
N Engl J Med 358:152-61. 2008..We assessed long-term clinical outcomes in athletes with ECGs characterized by marked repolarization abnormalities...
Prevalence and clinical significance of left atrial remodeling in competitive athletesAntonio Pelliccia
National Institute of Sports Medicine, Italian National Olympic Committee, Rome, Italy
J Am Coll Cardiol 46:690-6. 2005....
Relation between training-induced left ventricular hypertrophy and risk for ventricular tachyarrhythmias in elite athletesAlessandro Biffi
Institute of Sports Medicine and Science, Italian Olympic Committee, Rome, Italy
Am J Cardiol 101:1792-5. 2008..These data offer a measure of clinical reassurance regarding the benign nature of ventricular tachyarrhythmias in elite athletes and the expression of athlete's heart...
Gender-related differences in the clinical presentation and outcome of hypertrophic cardiomyopathyIacopo Olivotto
Regional Referral Center for Myocardial Diseases, Azienda Ospedaliera Universitaria Careggi, Florence, Italy
J Am Coll Cardiol 46:480-7. 2005..The goal of this study was to assess gender-related differences in a multicenter population with hypertrophic cardiomyopathy (HCM)...
Long-term effects of surgical septal myectomy on survival in patients with obstructive hypertrophic cardiomyopathySteve R Ommen
Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
J Am Coll Cardiol 46:470-6. 2005..This study sought to determine the impact of surgical myectomy on long-term survival in hypertrophic cardiomyopathy (HCM)...
Protecting our children from the consequences of chest blows on the playing field: a time for science over marketingMark S Link
Cardiac Arrhythmia Center, Tufts Medical Center, Boston, Massachusetts 02111, USA
Pediatrics 122:437-9. 2008
Sudden cardiac death caused by innocent chest wall blowsMark S Link
Ital Heart J 6:281-3. 2005
Role of streptomycin-sensitive stretch-activated channel in chest wall impact induced sudden death (commotio cordis)Arthur R Garan
New England Cardiac Arrhythmia Center, Tufts-New England Medical Center, Boston, Massachusetts, USA
J Cardiovasc Electrophysiol 16:433-8. 2005..However, streptomycin did reduce ST elevation following impact suggesting that the stretch-activated channel may play a role in ST segment elevation following chest wall blows...
Glycogen storage diseases presenting as hypertrophic cardiomyopathyMichael Arad
Division of Cardiology, Brigham and Women s Hospital, Boston, USA
N Engl J Med 352:362-72. 2005....
Electrophysiologic manifestations of ventricular tachyarrhythmias provoking appropriate defibrillator interventions in high-risk patients with hypertrophic cardiomyopathyYong Mei Cha
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905, USA
J Cardiovasc Electrophysiol 18:483-7. 2007..Our objective was to determine features of ventricular tachyarrhythmias triggering appropriate implantable cardioverter-defibrillator (ICD) interventions in hypertrophic cardiomyopathy (HCM)...
