Research Topics
| Jose CibelliSummaryAffiliation: Michigan State University Country: USA Publications
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Detail Information
Publications
Parthenogenetic activation of bovine oocytes using bovine and murine phospholipase C zetaPablo J Ross
Cellular Reprogramming Laboratory, Department of Animal Science, Michigan State University, East Lansing, MI 48824, USA
BMC Dev Biol 8:16. 2008..PLCZ1 has been identified as the factor that the sperm delivers into the egg to induce such a response. We tested the hypothesis that PLCZ1 cRNA injection can be used to activate bovine oocytes...
The human egg is backJose Cibelli
Departments of Animal Science and Physiology, Michigan State University, East Lansing, MI 48824, USA
Cell Stem Cell 5:345-6. 2009..The success of this technique may increase demand for human oocyte donation for research...
Development. Is therapeutic cloning dead?Jose Cibelli
Department of Animal Sciences, Cellular Reprogramming Laboratory, Michigan State University, East Lansing, MI 48824, USA
Science 318:1879-80. 2007
Cellular reprogramming for the creation of patient-specific embryonic stem cellsJose B Cibelli
Cellular Reprogramming Laboratory, Michigan State University, Michigan, USA
Stem Cell Rev 2:289-95. 2006..Herein we discuss the probability of somatic cell nuclear transfer becoming a real therapeutic alternative as well as the potential emerging dedifferentiation approaches that may eventually replace it...
Developmental biology. A decade of cloning mystiqueJose Cibelli
Departments of Animal Sciences and Physiology, Cellular Reprogramming Laboratory, Michigan State University, East Lansing, MI 48824, USA
Science 316:990-2. 2007
Activation of bovine somatic cell nuclear transfer embryos by PLCZ cRNA injectionPablo J Ross
Department of Animal Science, Michigan State University, East Lansing, Michigan 48824, USA
Reproduction 137:427-37. 2009..These results demonstrate that exogenous PLCZ can be used to activate bovine SCNT-derived embryos and support the hypothesis that a fertilization-like activation response can enhance some aspects of nuclear reprogramming...
Polycomb gene expression and histone H3 lysine 27 trimethylation changes during bovine preimplantation developmentPablo J Ross
Departments of, Animal Science Physiology, Michigan State University, East Lansing, Michigan 48824, USA
Reproduction 136:777-85. 2008..These results suggest that the absence of polycomb repressive complex 2 proteins localized to the nucleus of early embryos could be responsible for the gradual decrease in H3K27me3 during early preimplantation development...
Bovine ooplasm partially remodels primate somatic nuclei following somatic cell nuclear transferKai Wang
Michigan State University, East Lansing, 48824, USA
Cloning Stem Cells 11:187-202. 2009..Collectively, our results suggest that bovine ooplasm can partially remodel chimpanzee somatic nuclei, and provides insight into some of the current barriers iSCNT must overcome if further embryonic development is to be expected...
Bovine somatic cell nuclear transferPablo J Ross
Department of Animal Science, Michigan State University, East Lansing, MI, USA
Methods Mol Biol 636:155-77. 2010..Here we describe a basic protocol for bovine SCNT currently being used in our laboratory, which is amenable for the use of the nuclear transplantation technique for research or commercial purposes...
Embryonic stem cells from parthenotesJose B Cibelli
Department of Animal Science, Michigan State University, East Lansing, Michigan, USA
Methods Enzymol 418:117-35. 2006..This chapter describes the biology underlying parthenogenesis, as well as provides detailed technical considerations for the production of pESCs...
Characterization and in vitro control of MPF activity in zebrafish eggsKannika Siripattarapravat
Comparative Medicine and Integrative Biology Program College of Veterinary Medicine, Michigan State University, East Lansing, Michigan 48824, USA
Zebrafish 6:97-105. 2009..Conversely, nonactivated, aged matured eggs maintained high MPF activity and developmental potential when CSOF was used as a holding medium...
Transcriptional reprogramming of somatic cell nuclei during preimplantation development of cloned bovine embryosZeki Beyhan
Cellular Reprogramming Laboratory, B270 Anthony Hall, East Lansing, MI 48824, USA
Dev Biol 305:637-49. 2007..Our data provide the most comprehensive transcriptome database of bovine IVF and SCNT blastocysts to date...
Dynamic epigenetic regulation of the Oct4 and Nanog regulatory regions during neural differentiation in rhesus nuclear transfer embryonic stem cellsKai Wang
Michigan State University, East Lansing, Michigan, USA
Cloning Stem Cells 11:483-96. 2009....
Telomere dynamics in human cells reprogrammed to pluripotencySteven T Suhr
Cellular Reprogramming Laboratory, Department of Animal Science, Michigan State University, East Lansing, Michigan, United States of America
PLoS ONE 4:e8124. 2009..Studies of cloned animals indicate that somatic cells reprogrammed to pluripotency variably display telomere elongation, a common indicator of cell "rejuvenation."..
Trichostatin A improves histone acetylation in bovine somatic cell nuclear transfer early embryosAmy E Iager
Cellular Reprogramming Laboratory, Department of Animal Science, Michigan State University, East Lansing, Michigan 48824, USA
Cloning Stem Cells 10:371-9. 2008..However, evaluation of development to full-term is necessary to ascertain whether this effect reflects a true increase in developmental potential...
Increased cellular turnover in response to fluoxetine in neuronal precursors derived from human embryonic stem cellsEun Ah Chang
Animal Science, Michigan State University, East Lansing, MI 48824, USA
Int J Dev Biol 54:707-15. 2010....
The first human cloned embryoJose B Cibelli
Advanced Cell Technology, Worcester, Mass, USA
Sci Am 286:44-51. 2002
Parthenogenetic stem cells in nonhuman primatesJose B Cibelli
Advanced Cell Technology, One Innovation Drive, Worcester, MA 01605, USA
Science 295:819. 2002
The health profile of cloned animalsJose B Cibelli
Advanced Cell Technology, Worcester, MA, USA
Nat Biotechnol 20:13-4. 2002
Nonhuman primate parthenogenetic stem cellsKent E Vrana
Center for Neurobehavioral Study of Alcohol, Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
Proc Natl Acad Sci U S A 100:11911-6. 2003..These results suggest that stem cells derived from the parthenogenetically activated nonhuman primate egg provide a potential source for autologous cell therapy in the female and bypass the need for creating a competent embryo...
Effect of timing of the removal of oocyte chromosomes before or after injection of somatic nucleus on development of NT embryosSayaka Wakayama
Advanced Cell Technology, Worcester, Massachusetts, USA
Cloning Stem Cells 5:181-9. 2003..These findings argue that neither oocyte chromosome depletion per se, nor the potential removal of "reprogramming" factors during enucleation explain the low efficiency of nuclear transfer cloning...
Evidence of a pluripotent human embryonic stem cell line derived from a cloned blastocystWoo Suk Hwang
College of Veterinary Medicine, Seoul National University, Seoul 151 742, Korea
Science 303:1669-74. 2004..Although we cannot completely exclude the possibility that the cells had a parthenogenetic origin, imprinting analyses support a SCNT origin of the derived human ES cells...
Interspecies nuclear transfer: implications for embryonic stem cell biologyZeki Beyhan
Cellular Reprogramming Laboratory, Department of Animal Science, Michigan State University, B270 Anthony Hall, East Lansing, MI 48824, USA
Cell Stem Cell 1:502-12. 2007..This review focuses on the challenges and opportunities presented by the formidable task of overcoming biological differences among species...
Sperm mediated transgenesis rushes 'back to the future'Jose B Cibelli
Mol Ther 6:699-700. 2002
