Research Topics
Species | Sara A GeorgesSummaryAffiliation: Merck Research Laboratories Country: USA Publications
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Detail Information
Publications
Coordinated regulation of cell cycle transcripts by p53-Inducible microRNAs, miR-192 and miR-215Sara A Georges
Rosetta Inpharmatics LLC, Seattle, Washington WA 98109, USA
Cancer Res 68:10105-12. 2008..Our results showing a role for miR-192/215 in cell proliferation combined with recent observations that these miRNAs are underexpressed in primary cancers support the idea that miR-192 and miR-215 function as tumor suppressors...
An antisense transcript spanning the CGG repeat region of FMR1 is upregulated in premutation carriers but silenced in full mutation individualsPaula D Ladd
Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Hum Mol Genet 16:3174-87. 2007..Moreover, it exhibits premutation-specific alternative splicing. Taken together, these observations suggest that in addition to FMR1, ASFMR1 may contribute to the variable phenotypes associated with the CGG repeat expansion...
