Research Topics
Species | Jeffrey A SwitzerSummaryAffiliation: Medical College of Georgia Country: USA Publications
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Publications
Statins in stroke: prevention, protection and recoveryJeffrey A Switzer
Department of Neurology, Medical College of Georgia, Augusta, GA 30912, USA
Expert Rev Neurother 6:195-202. 2006..In addition, statins may have benefits in neuroprotection and recovery after stroke. The mechanisms by which statins protect against, and improve outcome after, stroke probably extend beyond lipid lowering...- Increased hemorrhagic transformation and altered infarct size and localization after experimental stroke in a rat model type 2 diabetesAdviye Ergul
Program in Clinical and Experimental Therapeutics, College of Pharmacy, University of Georgia, USA
BMC Neurol 7:33. 2007..Diabetes is a risk factor for stroke as well as poor outcome of stroke. The current study tested the hypothesis that diabetes-induced changes in the cerebral vasculature increase the risk of HT and augment ischemic injury... - Telestroke 10 years later--'telestroke 2.0'Jeffrey A Switzer
Department of Neurology, Medical College of Georgia, Augusta, GA 30912, USA
Cerebrovasc Dis 28:323-30. 2009..The lack of physicians with specialty stroke training represents a significant challenge to the future of stroke. This deficit limits both quality stroke care and clinical research initiatives... - A telestroke network enhances recruitment into acute stroke clinical trialsJeffrey A Switzer
DO, Department of Neurology, Medical College of Georgia, 1122 15th St, Augusta, GA 30912
Stroke 41:566-9. 2010..To save time, efforts are needed to enroll clinical trial subjects and begin the research drug at the remote site under telemedicine guidance... - Carotid stenosis: endarterectomy or angioplasty and stenting?Jeffrey A Switzer
Jeffrey A Switzer, DO Medical College of Georgia, 1122 15th Street, Augusta, GA 30912, USA
Curr Treat Options Neurol 9:451-62. 2007..However, it is unlikely that asymptomatic patients or symptomatic patients with moderate stenosis considered at high risk for endarterectomy would benefit from any intervention... - Are limb-shaking transient ischemic attacks a risk factor for postendarterectomy hemorrhage? Case report and literature reviewJeffrey A Switzer
Medical College of Georgia Neurology, Augusta, GA 30909, USA
J Neuroimaging 18:96-100. 2008..We propose that patients with limb-shaking transient ischemic attacks have loss of vasomotor reactivity placing them at high risk for carotid reperfusion syndrome and hemorrhage into the revascularized territory... - Development of regional programs to speed treatment of strokeJeffrey A Switzer
Department of Neurology, Medical College of Georgia, 1120 15th Street, Augusta, GA 30912, USA
Curr Neurol Neurosci Rep 8:35-42. 2008..Telestroke may be the best alternative in this scenario, extending acute stroke therapies to patients who would otherwise not receive treatment... - Matrix metalloproteinase-9 in an exploratory trial of intravenous minocycline for acute ischemic strokeJeffrey A Switzer
Department of Neurology, Medical College of Georgia, 1122 15th Street, Augusta, GA 30912, USA
Stroke 42:2633-5. 2011..Plasma matrix metalloproteinase-9 levels predict posttissue plasminogen activator (tPA) hemorrhage... - A web-based telestroke system facilitates rapid treatment of acute ischemic stroke patients in rural emergency departmentsJeffrey A Switzer
Department of Neurology, Medical College of Georgia, Augusta, Georgia 30912, USA
J Emerg Med 36:12-8. 2009..8 min in other published systems. REACH, a web-based telestroke system, facilitates the safe administration of thrombolytic therapy to patients within rural communities suffering an acute ischemic stroke... - Minocycline to improve neurologic outcome in stroke (MINOS): a dose-finding studySusan C Fagan
Departmentof Neurology, College of Pharmacy, University of Georgia, Medical College of Georgia, Augusta, GA 30912, USA
Stroke 41:2283-7. 2010..Minocycline is a promising anti-inflammatory and protease inhibitor that is effective in multiple preclinical stroke models. We conducted an early phase trial of intravenous minocycline in acute ischemic stroke... - Simplified modified rankin scale questionnaire: reproducibility over the telephone and validation with quality of lifeAskiel Bruno
Department of Neurology, Medical College of Georgia, Augusta, GA 30912, USA
Stroke 42:2276-9. 2011..The simplified modified Rankin Scale questionnaire (smRSq) enables a reliable and rapid determination of the modified Rankin Scale score after stroke. We test the reliability and validity of a slightly revised smRSq... - Improving modified Rankin Scale assessment with a simplified questionnaireAskiel Bruno
Department of Neurology, Medical College of Georgia, 1120 15th Street BI 3076, Augusta, GA 30912, USA
Stroke 41:1048-50. 2010..The modified Rankin Scale (mRS) is a popular primary stroke outcome measure, but its usefulness is limited by suboptimal reliability (inter-rater agreement)... - Pathophysiology and treatment of stroke in sickle-cell disease: present and futureJeffrey A Switzer
Department of Neurology, Medical College of Georgia, Augusta, GA 30912, USA
Lancet Neurol 5:501-12. 2006..Here we review the epidemiology, clinical spectrum, and pathophysiology of stroke in sickle-cell disease to identify potential therapeutic targets... - Use of telemedicine and helicopter transport to improve stroke care in remote locationsMihaela Saler
Department of Neurology, Georgia Health Sciences University, 1122 15th Street, Augusta, GA, 30912, USA
Curr Treat Options Cardiovasc Med 13:215-24. 2011..A cost-benefit analysis of telestroke is needed, although the recent proliferation of telestroke networks suggests an economic asset to some hospital systems... - Perspectives on telemedicine to improve stroke treatmentS F Stewart
Department of Neurology, Medical College of Georgia, Augusta, GA, USA
Drugs Today (Barc) 47:157-67. 2011..We conclude that telestroke is currently the most practical solution to any setback faced by stroke specialists with respect to low thrombolytic rates... - Statin therapy for coronary heart disease and its effect on strokeJeffrey A Switzer
Curr Atheroscler Rep 8:337-42. 2006....