Research Topics
Species | Michael OlivierSummaryAffiliation: Medical College of Wisconsin Country: USA Publications
| Collaborators
|
Detail Information
Publications
The Invader assay for SNP genotypingMichael Olivier
Human and Molecular Genetics Center, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
Mutat Res 573:103-10. 2005....- Obesity-related dyslipidemia associated with FAAH, independent of insulin response, in multigenerational families of Northern European descentYi Zhang
Medical College of Wisconsin, Milwaukee, Wisconsin, WI 53226, USA
Pharmacogenomics 10:1929-39. 2009..In recent years, there has been tremendous interest in understanding the endocannabinoid system as a novel therapeutic target for the treatment of obesity-related dyslipidemia... - Analysis of concordance of different haplotype block partitioning algorithmsAmit R Indap
Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, USA
BMC Bioinformatics 6:303. 2005.... - A novel procedure for genotyping of single nucleotide polymorphisms in trisomy with genomic DNA and the invader assayKelly J Duffy
Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, WI, USA
Nucleic Acids Res 36:e145. 2008.... - Putting the Invader assay to work: laboratory application and data managementYi Zhang
Biotechnology and Bioengineering Center, Medical College of Wisconsin, Milwaukee, WI, USA
Methods Mol Biol 578:363-77. 2009..Here, from an end-user point of view, we discuss how a commercially available genotyping platform, the Invader assay, can be utilized to meet the needs and demands of human genomic research in a laboratory... - Genetic linkage and association of the growth hormone secretagogue receptor (ghrelin receptor) gene in human obesityAndrea Baessler
Department of Physiology, Human and Molecular Genetics Center, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226, USA
Diabetes 54:259-67. 2005.... - ZoomQuant: an application for the quantitation of stable isotope labeled peptidesBrian D Halligan
Bioinformatics, Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, Wisconsin 53213, USA
J Am Soc Mass Spectrom 16:302-6. 2005..Finally, ZoomQuant generates a summary report of the relative abundance of the peptides identified in the two samples... - Simultaneous quantification and identification using 18O labeling with an ion trap mass spectrometer and the analysis software application "ZoomQuant"Wayne A Hicks
National Proteomics Research Center, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53213, USA
J Am Soc Mass Spectrom 16:916-25. 2005..This compares well with data produced from (18)O labeling experiments using time of flight (TOF) and Fourier transform-ion cyclotron resonance (FT-ICR) MS instruments... - Obesity and its therapy: from genes to community actionJoseph A Skelton
Division of Pediatric Gastroenterology and Nutrition, Medical College of Wisconsin, 8701 Watertown Plank Road, PO Box 26509, Milwaukee, WI 53226, USA
Pediatr Clin North Am 53:777-94. 2006..Many of these behaviors are being evaluated in animal models and hold great promise for targeted interventions in the future... - Improved method for the analysis of membrane proteins by mass spectrometryShama P Mirza
National Center for Proteomics Research, Biotechnology and Bioengineering Center, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
Physiol Genomics 30:89-94. 2007..Comparison of our results to results obtained by direct tryptic digestion of insoluble membrane pellets identifies an increased number of membrane proteins, and a higher quality of the resulting mass spectral data... - Methods and approaches for the comprehensive characterization and quantification of cellular proteomes using mass spectrometryShama P Mirza
National Center for Proteomics Research, Biotechnology and Bioengineering Center, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA E mail
Physiol Genomics 33:3-11. 2008.... - 18O labeling over a coffee break: a rapid strategy for quantitative proteomicsShama P Mirza
National Center for Proteomics Research, Biotechnology and Bioengineering Center, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
J Proteome Res 7:3042-8. 2008..We demonstrate the efficiency and accuracy of the method using a four protein mixture and whole cell lysate from rat vascular endothelial cells... - Hepatic gene networks in morbidly obese patients with nonalcoholic fatty liver diseaseSamer Gawrieh
Department of Medicine, Division of Gastroenterology and Hepatology, Medical College of Wisconsin, Milwaukee, WI 53212, USA
Obes Surg 20:1698-709. 2010..Genetic factors alter the risk for nonalcoholic fatty liver disease (NAFLD). We sought to identify NAFLD-associated genes and elucidate gene networks and pathways involved in the pathogenesis of NAFLD... - High-throughput genotyping of single nucleotide polymorphisms using new biplex invader technologyMichael Olivier
Stanford Human Genome Center, Stanford University School of Medicine, 975 California Avenue, Palo Alto, CA 94305, USA
Nucleic Acids Res 30:e53. 2002..The biplex invader assay with its automated set-up and analysis offers a new efficient high-throughput genotyping platform that is suitable for association studies in large study cohorts... - Single nucleotide polymorphisms in protein tyrosine phosphatase 1beta (PTPN1) are associated with essential hypertension and obesityMichael Olivier
Stanford Human Genome Center, Stanford University School of Medicine, CA, USA
Hum Mol Genet 13:1885-92. 2004..Given similar associations found in other populations to insulin resistance and diabetes, this gene may play a crucial role in the development of the characteristic metabolic changes seen in patients with the metabolic syndrome... - Haplotype analysis of the apolipoprotein gene cluster on human chromosome 11Michael Olivier
Human and Molecular Genetics Center, Department of Physiology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
Genomics 83:912-23. 2004..These results highlight the complex genetic relationship between APOA5 and APOC3 and support the notion that APOA5 represents an independent risk gene affecting plasma triglyceride concentrations in humans... - Genetic determinants of obesity-related lipid traitsGabriele E Sonnenberg
Division of Endocrinology, Metabolism and Clinical Nutrition, Department of Medicine and Human Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, WI, USA
J Lipid Res 45:610-5. 2004..These newly identified loci likely harbor genetic elements that influence traits underlying lipid adversities associated with obesity... - Insights into Dahl salt-sensitive hypertension revealed by temporal patterns of renal medullary gene expressionMingyu Liang
Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
Physiol Genomics 12:229-37. 2003.... - Relative quantification of peptide phosphorylation in a complex mixture using 18O labelingJulia R Smith
Biotechnology and Bioengineering Center, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
Physiol Genomics 31:357-63. 2007.... - Gene expression reveals vulnerability to oxidative stress and interstitial fibrosis of renal outer medulla to nonhypertensive elevations of ANG IIBaozhi Yuan
Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
Am J Physiol Regul Integr Comp Physiol 284:R1219-30. 2003.... - Sequential abundant ion fragmentation analysis (SAIFA): an alternative approach for phosphopeptide identification using an ion trap mass spectrometerMarla Chesnik
Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI 53226, USA
Anal Biochem 418:197-203. 2011..To the best of our knowledge, this is the first report to use SAIFA for phosphopeptide identification... - Automated SNP genotype clustering algorithm to improve data completeness in high-throughput SNP genotyping datasets from custom arraysEdward M Smith
Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA
Genomics Proteomics Bioinformatics 5:256-9. 2007..This analysis suggests that the use of multiple genotype calling algorithms may be advisable in high-throughput SNP genotyping experiments. The software is written in Perl and is available from the corresponding author... - Integrated approach for the comprehensive characterization of lipoproteins from human plasma using FPLC and nano-HPLC-tandem mass spectrometryLisamarie A Collins
Biotechnology and Bioengineering Center, Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
Physiol Genomics 40:208-15. 2010.... - Genetic variation in cannabinoid receptor 1 (CNR1) is associated with derangements in lipid homeostasis, independent of body mass indexTes M Baye
Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
Pharmacogenomics 9:1647-56. 2008..We therefore tested the hypothesis that genetic variation in CNR1 is associated with common obesity-related metabolic disorders... - Quantitative comparison of lipoprotein fractions derived from human plasma and serum by liquid chromatography-tandem mass spectrometryLisamarie A Collins
Biotechnology and Bioengineering Center, Medical College of Wisconsin, Milwaukee, WI, USA
Proteome Sci 8:42. 2010..After delipidating these samples, we performed a quantitative proteomic analysis to compare the lipoprotein-associated proteins derived from both plasma and serum... - Radiation hybrid mapping with BAC endsMichael Olivier
Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, USA
Methods Mol Biol 255:163-9. 2004 - Two independent apolipoprotein A5 haplotypes influence human plasma triglyceride levelsLen A Pennacchio
Genome Sciences Department, MS 84 171, Lawrence Berkeley National Laboratory, One Cyclotron Road, Berkeley, CA 94720, USA
Hum Mol Genet 11:3031-8. 2002..Together, the APOA5*2 and APOA5*3 haplotypes are found in 25-50% of African-Americans, Hispanics and Caucasians and support the contribution of common human variation to quantitative phenotypes in the general population... - Relative contribution of variation within the APOC3/A4/A5 gene cluster in determining plasma triglyceridesPhilippa J Talmud
Division of Cardiovascular Genetics, Department of Medicine, British Heart Foundation Laboratories, Rayne Building, Royal Free and University College Medical School, 5 University Street, London WC1E 6JJ, UK
Hum Mol Genet 11:3039-46. 2002..The molecular mechanisms for these effects remain to be determined... - A haplotype map of the human genomeMichael Olivier
Physiol Genomics 13:3-9. 2003 - Linkage and association between distinct variants of the APOA1/C3/A4/A5 gene cluster and familial combined hyperlipidemiaSophie Eichenbaum-Voline
Genomic and Molecular Medicine Group, Medical Research Council Clinical Sciences Centre, Hammersmith Hospital, London, UK
Arterioscler Thromb Vasc Biol 24:167-74. 2004..CONCLUSIONS: A combined linkage and association analysis establishes that variation at the APOA1/C3/A4/A5 gene cluster contributes to FCHL transmission in a substantial proportion of northern European families... - From SNPs to function: the effect of sequence variation on gene expression. Focus on "a survey of genetic and epigenetic variation affecting human gene expression"Michael Olivier
Physiol Genomics 16:182-3. 2004 - Parallel single nucleotide polymorphism genotyping by surface invasive cleavage with universal detectionYan Chen
Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, Wisconsin 53706, USA
Anal Chem 77:2400-5. 2005.... - Characterization of vascular endothelial growth factor receptors on the endothelial cell surface during hypoxia using whole cell binding arraysJi Eun Lee
Department of Chemistry, University of Wisconsin Madison, Madison, WI 53706, USA
Anal Biochem 369:241-7. 2007..This result implicates the dysregulation of VEGF receptor expression levels on the endothelial cell surface as a key factor in impaired angiogenesis... - Linkage and segregation analysis of black and brindle coat color in domestic dogsJulie A Kerns
Department of Genetics, Stanford University, Stanford, California 94035, USA
Genetics 176:1679-89. 2007..These findings suggest a molecular model for a new component of the melanocortin signaling pathway and reveal how coat-color patterns and pigmentary diversity have been shaped by recent selection... - Tree-structured supervised learning and the genetics of hypertensionJing Huang
Affymetrix Inc, 3380 Central Expressway, Santa Clara, CA 95051, USA
Proc Natl Acad Sci U S A 101:10529-34. 2004..FlexTree and Logic Regression appear better than the others in terms of Bayes risk. However, the differences are not significant in the usual statistical sense...