Research Topics
| V MironovSummaryAffiliation: Medical University of South Carolina Country: USA Publications
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Detail Information
Publications
Organ printing: tissue spheroids as building blocksVladimir Mironov
Bioprinting Research Center, Cardiovascular Developmental Biology Center, Department of Cell Biology and Anatomy, Medical University of South Carolina, Charleston, SC 29425, USA
Biomaterials 30:2164-74. 2009..Thus, organ printing is a new emerging enabling technology paradigm which represents a developmental biology-inspired alternative to classic biodegradable solid scaffold-based approaches in tissue engineering...
Cardiovascular tissue engineering I. Perfusion bioreactors: a reviewVladimir Mironov
Medical University of South Carolina, Cell Biology and Anatomy Department, Charleston, South Carolina 29425, USA
J Long Term Eff Med Implants 16:111-30. 2006....
Research project: Charleston Bioengineered Kidney ProjectVladimir Mironov
Bioprinting Research Center, Medical University of South Carolina, Charleston, SC, USA
Biotechnol J 1:903-5. 2006..The potential challenges are described. Finally, the experts' opinion about the proposed project is also presented...
The Second International Workshop on Bioprinting, Biopatterning and BioassemblyVladimir Mironov
Medical University of South Carolina, Department of Cell Biology and Anatomy, PO Box 250508, Charleston, SC 29425, USA
Expert Opin Biol Ther 5:1111-5. 2005..The Third International Workshop on Bioprinting, Biopatterning and Bioassembly is planned for Japan in 2006...
Fabrication of tubular tissue constructs by centrifugal casting of cells suspended in an in situ crosslinkable hyaluronan-gelatin hydrogelVladimir Mironov
Medical University of South Carolina, Charleston, SC 29426, USA
Biomaterials 26:7628-35. 2005..Centrifugal casting in this sECM would enable rapid fabrication of tissue-engineered vascular grafts, as well as other tubular and planar tissue-engineered constructs...
Organ printing: promises and challengesVladimir Mironov
Medical University of South Carolina, Department of Cell Biology and Anatomy, Charleston, South Carolina, USA
Regen Med 3:93-103. 2008..This article describes conceptual framework and recent developments in organ-printing technology, outlines main technological barriers and challenges, and presents potential future practical applications...
Bioreactor-free tissue engineering: directed tissue assembly by centrifugal castingVladimir Mironov
Medical University of South Carolina, Charleston, SC 29425, USA
Expert Opin Biol Ther 8:143-52. 2008..Herein the authors summarize the state of the art of centrifugal casting technology in tissue engineering, they outline associated technological challenges, and they discuss the potential future for clinical applications...
Nanotechnology in vascular tissue engineering: from nanoscaffolding towards rapid vessel biofabricationVladimir Mironov
Bioprinting Research Center, Department of Cell Biology and Anatomy, Medical University of South Carolina, 173 Ashley Avenue, Charleston, SC 29425, USA
Trends Biotechnol 26:338-44. 2008....
Perfusion bioreactor for vascular tissue engineering with capacities for longitudinal stretchVladimir Mironov
Department of Cell Biology and Anatomy, Medical University of South Carolina, 173 Ashley Avenue, Suite 651, PO Box 250508, Charleston, SC 29425, USA
J Craniofac Surg 14:340-7. 2003..This allows the recording of a relationship between the radius of the VTEG and pressure in both static and dynamic regimens. This bioreactor can perform biomechanical conditioning with longitudinal strain...
Organ printing: from bioprinter to organ biofabrication lineVladimir Mironov
Advanced Tissue Biofabrication Center, Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina, 173 Ashley Avenue, Charleston, SC 29425, USA
Curr Opin Biotechnol 22:667-73. 2011..This paper presents recent progress and challenges in the development of the essential components of an organ biofabrication line...
Organ printing: computer-aided jet-based 3D tissue engineeringVladimir Mironov
Department of Cell Biology and Anatomy, Medical University of South Carolina, Charleston, SC 29425, USA
Trends Biotechnol 21:157-61. 2003....
Rapid biofabrication of tubular tissue constructs by centrifugal casting in a decellularized natural scaffold with laser-machined microporesVladimir A Kasyanov
Medical University of South Carolina, Charleston, SC 29426, USA
J Mater Sci Mater Med 20:329-37. 2009....
Biofabrication: a 21st century manufacturing paradigmV Mironov
Medical University of South Carolina, Charleston, SC 29425, USA
Biofabrication 1:022001. 2009....
Scalable robotic biofabrication of tissue spheroidsA Nagy Mehesz
Advanced Tissue Biofabrication Center, Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, USA
Biofabrication 3:025002. 2011..Thus, use of micromolded recessions in a non-adhesive hydrogel, combined with automated cell seeding, is a reliable method for scalable robotic fabrication of uniform-sized tissue spheroids...
Tannic acid mimicking dendrimers as small intestine submucosa stabilizing nanomordantsVladimir Kasyanov
Medical University of South Carolina, Charleston, SC 29425, USA
Biomaterials 27:745-51. 2006....
Periostin regulates collagen fibrillogenesis and the biomechanical properties of connective tissuesRussell A Norris
Department of Cell Biology and Anatomy, Medical University of South Carolina, Charleston, South Carolina 29425, USA
J Cell Biochem 101:695-711. 2007..Collectively, these data demonstrate for the first time that periostin can regulate collagen I fibrillogenesis and thereby serves as an important mediator of the biomechanical properties of fibrous connective tissues...
Toward human organ printing: Charleston Bioprinting SymposiumVladimir Mironov
Bioprinting Research Center, Medical University of South Carolina, Charleston, South Carolina 29425, USA
ASAIO J 52:e27-30. 2006..The symposium demonstrated that although there are still many technological challenges, organ printing is a rapidly evolving feasible technology...
American Association of Anatomists meeting on regenerative medicineVladimir Mironov
Medical University of South Carolina, Department of Cell Biology and Anatomy, PO Box 250508, Charleston, SC 29425, USA
Expert Opin Biol Ther 6:727-30. 2006....
Towards organ printing: engineering an intra-organ branched vascular treeRichard P Visconti
Medical University of South Carolina, Bioprinting Research Center, Department of Regenerative Medicine and Cell Biology, 173 Ashley Avenue, Charleston, SC 29425, USA
Expert Opin Biol Ther 10:409-20. 2010..Despite this requirement, current tissue-engineering efforts are still focused predominantly on engineering either large-diameter macrovessels or microvascular networks...
What is regenerative medicine? Emergence of applied stem cell and developmental biologyV Mironov
Medical University of South Carolina, Charleston, SC 29425, USA
Expert Opin Biol Ther 4:773-81. 2004..Regenerative medicine is, at its essence, an emergence of applied stem cell and developmental biology...
Review: bioprinting: a beginningVladimir Mironov
Department of Cell Biology and Anatomy, Medical University of South Carolina, Charleston, USA
Tissue Eng 12:631-4. 2006..Here we present a short review regarding the framework, state of the art, and perspectives of this new field, based on the findings presented at a recent international workshop...
Organ printing: fiction or scienceKaroly Jakab
Department of Physics, University of Missouri, Columbia, MO 65211, USA
Biorheology 41:371-5. 2004..The simulations reproduced the experimentally observed cellular arrangements and revealed that the control parameter of pattern evolution is the gel-tissue interfacial tension, an experimentally accessible parameter...
Cell and organ printing 2: fusion of cell aggregates in three-dimensional gelsThomas Boland
Department of Bioengineering, Clemson University, Clemson, South Carolina 29634, USA
Anat Rec A Discov Mol Cell Evol Biol 272:497-502. 2003..Finally, we demonstrated that these closely-placed cell aggregates could fuse in two types of thermosensitive 3D gels. Taken together, these data strongly support the feasibility of the proposed novel organ-printing technology...
Printing technology to produce living tissueVladimir Mironov
Expert Opin Biol Ther 3:701-4. 2003
Engineering biological structures of prescribed shape using self-assembling multicellular systemsKaroly Jakab
Department of Physics, University of Missouri, Columbia, MO 65211, USA
Proc Natl Acad Sci U S A 101:2864-9. 2004..Thus, these constructs can be made long-lived. We suggest that spherical aggregates composed of organ-specific cells may be used as "bio-ink" in the evolving technology of organ printing...
Tissue engineering by self-assembly of cells printed into topologically defined structuresKaroly Jakab
Department of Physics, University of Missouri, Columbia, Missouri 65211, USA
Tissue Eng Part A 14:413-21. 2008..The postprinting self-assembly of bio-ink particles resulted in synchronously beating solid tissue blocks, showing signs of early vascularization, with the endothelial cells organized into vessel-like conduits...
Tuning the cell-cycle engine for improved plant performanceGerrit T S Beemster
Department of Plant Systems Biology, Flanders Interuniversity Institute for Biotechnology (VIB)/Ghent University, Technologiepark 927, Ghent, Belgium
Curr Opin Biotechnol 16:142-6. 2005..Nevertheless, ten years of molecular cell-cycle research, primarily in the model plant Arabidopsis, have demonstrated its potential for altering plant development...
On the role of endothelial progenitor cells in tumor neovascularizationNatalia L Komarova
Department of Mathematics and Ecology and Evolution, University of California, Irvine, CA 92697 3875, USA
J Theor Biol 235:338-49. 2005..We show how our results can help explain some apparently contradictory experimental data. We also propose ways to couple this study with directed experiments to identify the exact role of vasculogenesis in tumor progression...
