Research Topics
| R T MeansSummaryAffiliation: Medical University of South Carolina Country: USA Publications
Research Grants
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Detail Information
Publications
Advances in the anemia of chronic diseaseR T Means
Hematology Oncology Division, Ralph H Johnson VA Medical Center, Charleston, South Carolina, USA
Int J Hematol 70:7-12. 1999..In this review, advances in the understanding of the diagnostic, pathophysiologic, and therapeutic aspects of this syndrome are summarized...- Recent developments in the anemia of chronic diseaseRobert T Means
Hematology Oncology Division, Medical University of South Carolina, 903 CSB, 96 Jonathan Lucas Street, Charleston, SC 29425, USA
Curr Hematol Rep 2:116-21. 2003..Ongoing studies of the mechanisms contributing to the development of ACD continue to elucidate the pathogenesis of this common and clinically significant syndrome... - Serum hepcidin in clinical specimensGail Dallalio
Hematology Oncology Division, Department of Medicine, Ralph H Johnson VA Medical Center and the Medical University of South Carolina, Charleston, SC 29425, USA
Br J Haematol 122:996-1000. 2003.... - Hepcidin and anaemiaRobert T Means
Hematology Oncology Division, Department of Medicine, Ralph H Johnson VA Medical Center and the Medical University of South Carolina, 903 CSB, 96 Jonathan Lucas Street, Charleston, SC 29425, USA
Blood Rev 18:219-25. 2004..It seems very likely that hepcidin is a major contributor to iron abnormalities characteristic of ACD; whether it contributes to the pathogenesis of the syndrome in a broader sense remains to be determined by further investigation... - Cytokines and anaemia in human immunodeficiency virus infectionR T Means
Hematology Oncology Division, University of Cincinnati College of Medicine, OH, USA
Cytokines Cell Mol Ther 3:179-86. 1997..These cytokines are also implicated in HIV-related anaemia. In this review, the applicability of this cytokine-mediated anaemia model to the anaemia of HIV infection is explored... - Unanticipated favorable effects of correcting iron deficiency in chronic hemodialysis patientsV E Pollak
Department of Medicine, University of Colorado Health Sciences Center, Denver, USA
J Investig Med 49:173-83. 2001..Correction of anemia in hemodialysis patients is seldom completely attained, and the response of parameters other than hemoglobin concentration to anemia correction has not been evaluated in detail... - Hepcidin and cytokines in anaemiaRobert T Means
Medical Service, VA Medical Center, Lexington, KY 40502, USA
Hematology 9:357-62. 2004..Hepcidin appears to be a major factor in the systemic iron abnormalities seen in ACD; whether it contributes to the other aspects of the pathogenesis of the syndrome requires further investigation... - Hepcidin inhibits in vitro erythroid colony formation at reduced erythropoietin concentrationsGail Dallalio
Medical Service 111, VA Medical Center Rm A 429, 1101 Veterans Dr, Lexington, KY
Blood 107:2702-4. 2006..These studies suggest that hepcidin may contribute to anemia in ACD not only through effects on iron metabolism, but also through inhibition of erythroid progenitor proliferation and survival... - Cytokine concentrations in bone marrow of stable sickle cell anemia patientsGail Dallalio
Veterans Affairs Medical Center, University of Kentucky, Lexington Markey Cancer Center, KY 40502, USA
J Investig Med 55:69-74. 2007..This suggests that the observed difference in marrow PlGF concentrations does not reflect increased erythropoiesis but rather represents increased PlGF production per erythroid unit...
Research Grants
- Inflammatory control of erythropoiesis in sickle diseaseRobert Means; Fiscal Year: 2004....