Lesleyann Hawthorn

Summary

Affiliation: Medical College of Georgia
Country: USA

Publications

  1. ncbi Normal colon epithelium: a dataset for the analysis of gene expression and alternative splicing events in colon disease
    Wilfrido Mojica
    Molecular Oncology Program, Medical College of Georgia Cancer Center, Augusta, GA, USA
    BMC Genomics 11:5. 2010
  2. ncbi Integration of transcript expression, copy number and LOH analysis of infiltrating ductal carcinoma of the breast
    Lesleyann Hawthorn
    Medical College of Georgia Cancer Center, 1120 15th St, Augusta, GA 30912, USA
    BMC Cancer 10:460. 2010
  3. ncbi Analysis of wilms tumors using SNP mapping array-based comparative genomic hybridization
    Lesleyann Hawthorn
    School of Medicine, MCG Cancer Center, Medical College of Georgia, Augusta, Georgia, United States of America
    PLoS ONE 6:e18941. 2011
  4. ncbi Interpreting aCGH-defined karyotypic changes in gliomas using copy number status, loss of heterozygosity and allelic ratios
    John K Cowell
    Medical College of Georgia Cancer Center, CN4112, Medical College of Georgia, 1120 15th Street, Augusta, GA 30912, USA
    Exp Mol Pathol 88:82-9. 2010
  5. ncbi Reexpression of LGI1 in glioma cells results in dysregulation of genes implicated in the canonical axon guidance pathway
    Padmaja Kunapuli
    MCG Cancer Center, Medical College of Georgia, Augusta, 30912, USA
    Genomics 95:93-100. 2010

Collaborators

Detail Information

Publications5

  1. ncbi Normal colon epithelium: a dataset for the analysis of gene expression and alternative splicing events in colon disease
    Wilfrido Mojica
    Molecular Oncology Program, Medical College of Georgia Cancer Center, Augusta, GA, USA
    BMC Genomics 11:5. 2010
    ....
  2. ncbi Integration of transcript expression, copy number and LOH analysis of infiltrating ductal carcinoma of the breast
    Lesleyann Hawthorn
    Medical College of Georgia Cancer Center, 1120 15th St, Augusta, GA 30912, USA
    BMC Cancer 10:460. 2010
    ..This integrated analysis permits the identification of genes with altered expression that map within specific chromosomal regions which demonstrate copy number alterations, providing a mechanistic approach to identify the 'driver genes'...
  3. ncbi Analysis of wilms tumors using SNP mapping array-based comparative genomic hybridization
    Lesleyann Hawthorn
    School of Medicine, MCG Cancer Center, Medical College of Georgia, Augusta, Georgia, United States of America
    PLoS ONE 6:e18941. 2011
    ..Analysis of CNAs by tumor stage show relatively stable karyotypes in stage 1 tumors and more complex aCGH profiles in tumors from stages 3-5...
  4. ncbi Interpreting aCGH-defined karyotypic changes in gliomas using copy number status, loss of heterozygosity and allelic ratios
    John K Cowell
    Medical College of Georgia Cancer Center, CN4112, Medical College of Georgia, 1120 15th Street, Augusta, GA 30912, USA
    Exp Mol Pathol 88:82-9. 2010
    ..Overall, this analysis of gliomas provides evidence for the need to perform more comprehensive interpretation of the CGH data beyond copy number analysis alone to evaluate the significance of individual events in the karyotypes...
  5. ncbi Reexpression of LGI1 in glioma cells results in dysregulation of genes implicated in the canonical axon guidance pathway
    Padmaja Kunapuli
    MCG Cancer Center, Medical College of Georgia, Augusta, 30912, USA
    Genomics 95:93-100. 2010
    ..In addition, this observation provides a mechanistic link for LGI1's common role in metastasis and epilepsy development...