Research Topics
| Dieter HaemmerichSummaryAffiliation: Medical University of South Carolina Country: USA Publications
Research Grants
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Detail Information
Publications
Effect of variable heat transfer coefficient on tissue temperature next to a large vessel during radiofrequency tumor ablationIcaro dos Santos
Department of Electrical Engineering, University of Brasilia, Brasilia, DF 70910 900, Brazil
Biomed Eng Online 7:21. 2008..However, the actual distribution of the temperature on the vessel wall is non-uniform and time-varying, and this feature makes the convective coefficient variable...- Biophysics of radiofrequency ablationDieter Haemmerich
Department of Pediatrics, Medical University of South Carolina, Charleston, SC 29425, USA
Crit Rev Biomed Eng 38:53-63. 2010..Procedures and devices specific for cancer treatment and for arrhythmia treatment are presented with a brief discussion of additional clinical applications... - Hepatic radiofrequency ablation at low frequencies preferentially heats tumour tissueDieter Haemmerich
Department of Pediatrics, Medical University of South Carolina, Charleston, SC 29425, USA
Int J Hyperthermia 22:563-74. 2006.... - Automatic control of finite element models for temperature-controlled radiofrequency ablationDieter Haemmerich
Division of Pediatric Cardiology, Medical University of South Carolina, 165 Ashley Ave, Charleston, SC 29425, USA
Biomed Eng Online 4:42. 2005..Commercial FEM packages don't support automating temperature control. Most researchers manually control the applied power by trial and error to keep the tip temperature of the electrodes constant... - In vitro measurements of temperature-dependent specific heat of liver tissueDieter Haemmerich
Children s Hospital, Medical University of South Carolina, Department of Pediatrics, 165 Ashley Ave, PO Box 250915, Charleston, SC 29425, USA
Med Eng Phys 28:194-7. 2006..5 degrees C. Water loss from the samples was significant above 70 degrees C, with approximately 20% of reduction in sample mass at 90 degrees C... - Electrical conductivity measurement of excised human metastatic liver tumours before and after thermal ablationDieter Haemmerich
Department of Pediatrics, Medical University of South Carolina, Charleston, SC, USA
Physiol Meas 30:459-66. 2009..43-0.40 at 1 MHz), while normal tissue conductivity increased by +270% and +10% at 10 Hz and 1 MHz (0.09-0.32 at 10 Hz and 0.37-0.41 at 1 MHz). These data can potentially be used to differentiate tumour from normal tissue diagnostically... - RF ablation at low frequencies for targeted tumor heating: in vitro and computational modeling resultsDieter Haemmerich
Division of Pediatric Cardiology, Medical Universityof South Carolina, Charleston, SC 29403, USA
IEEE Trans Biomed Eng 58:404-10. 2011..Heating at low RFs may thus allow targeted heating of tumor tissue and reduced heating of normal tissue... - Mathematical modeling of impedance controlled radiofrequency tumor ablation and ex-vivo validationDieter Haemmerich
Division of Pediatric Cardiology, Medical University of South Carolina, Charleston, SC 29403, USA
Conf Proc IEEE Eng Med Biol Soc 2010:1605-8. 2010..Ablation zone diameter was 33 mm in the computer model, and 29 ± 3 mm in the experiments. Our computer model may more accurately allow tissue temperature calculation via including power control algorithms as used in clinical devices... - Sequential activation of ground pads reduces skin heating during radiofrequency ablation: initial in vivo porcine resultsDavid J Schutt
Medical University of South Carolina, Charleston, SC 29425, USA
Conf Proc IEEE Eng Med Biol Soc 2009:4287-90. 2009..Skin burns below ground pads during RF ablations are increasingly prevalent, hindering the development of higher-power RF generators capable of creating larger ablation zones... - Effects of variation in perfusion rates and of perfusion models in computational models of radio frequency tumor ablationDavid J Schutt
Department of Pediatrics, Medical University of South Carolina, Charleston, South Carolina 29425, USA
Med Phys 35:3462-70. 2008..They also examine the effect of tissue type and inter-patient variation of perfusion on ablation zone dimensions... - Tumor ablation at low frequencies for preferential tumor heating: initial ex-vivo tissue studiesDavid J Schutt
Medical University of South Carolina, Charleston, SC 29425, USA
Conf Proc IEEE Eng Med Biol Soc 2008:238-41. 2008..In this study, we investigated in an ex vivo setting whether the use of lower frequencies during ablation results in preferential heating of tumor tissue... - Contrasting effects of convective flow on catheter ablation lesion size: cryo versus radiofrequency energyThomas A Pilcher
Division of Pediatric Cardiology, Medical University of South Carolina, Charleston, South Carolina 29425, USA
Pacing Clin Electrophysiol 31:300-7. 2008..We compared the effects of convective flow on large-tip cryo and radiofrequency (RF) lesions dimensions... - Sequential activation of ground pads reduces skin heating during radiofrequency tumor ablation: in vivo porcine resultsDavid J Schutt
Division of Pediatric Cardiology, Medical University of South Carolina, Charleston, SC 29403 USA
IEEE Trans Biomed Eng 57:746-53. 2010..9 +/- 0.3, 5.6 +/- 0.3, and 7.5 +/- 0.6 cm, respectively. Sequential activation of multiple ground pads results in significantly lower skin temperatures and less severe burns, as measured by histological examination... - Convective cooling affects cardiac catheter cryoablation and radiofrequency ablation in opposite directionsDieter Haemmerich
Medical University of South Carolina, Division of Pediatric Cardiology, Charleston, SC 29414, USA
Conf Proc IEEE Eng Med Biol Soc 2007:1499-502. 2007..01). While RF ablation creates larger lesions at high flow rates (3 L/min), cryoablation creates larger lesions at low flow rates (0-1 L/min, p<0.05)... - Effect of electrode thermal conductivity in cardiac radiofrequency catheter ablation: a computational modeling studyDavid Schutt
Medical University of South Carolina, Charleston, South Carolina, Charleston, SC 29425, USA
Int J Hyperthermia 25:99-107. 2009..In this study we created computer models to compare the effects of different electrode materials on lesion dimensions using different catheters, insertion depths, and flow rates... - Measurement of temperature-dependent specific heat of biological tissuesDieter Haemmerich
Division of Pediatric Cardiology, Medical University of South Carolina, Charleston, SC 29425, USA
Physiol Meas 26:59-67. 2005..We confirm method accuracy with a 2.5% agar-0.4% saline physical model and obtain specific heat of 4121+/-89 J (kg K)(-1), with an average error of 3.1%... - Sequential activation of a segmented ground pad reduces skin heating during radiofrequency tumor ablation: optimization via computational modelsDavid J Schutt
Division of Pediatric Cardiology, Medical University of South Carolina, Charleston, SC 29425, USA
IEEE Trans Biomed Eng 55:1881-9. 2008..Sequential activation of a segmented ground pad resulted in lower tissue temperatures. This method may reduce the incidence of ground pad burns and enable the use of higher power generators during RF tumor ablation... - Mathematical spatio-temporal model of drug delivery from low temperature sensitive liposomes during radiofrequency tumour ablationAstrid Gasselhuber
Medical University of South Carolina, Charleston, South Carolina, USA
Int J Hyperthermia 26:499-513. 2010.... - Convective cooling effect on cooled-tip catheter compared to large-tip catheter radiofrequency ablationThomas A Pilcher
Division of Pediatric Cardiology, Medical University of South Carolina, Charleston, South Carolina 29425, USA
Pacing Clin Electrophysiol 29:1368-74. 2006..At low flow rates (0-1 L/min) cooled-tip catheters create larger lesions, while at high flow rates (3 L/min) large-tip catheters create larger lesions... - Sequential activation of multiple grounding pads reduces skin heating during radiofrequency tumor ablationDieter Haemmerich
Medical University of South Carolina, Department of Pediatrics, Charleston, SC 29425, USA
Int J Hyperthermia 23:555-66. 2007..We investigated a method were groups of ground pads are sequentially activated to reduce skin heating... - Contribution of direct heating, thermal conduction and perfusion during radiofrequency and microwave ablationWolfgang Schramm
Div of Pediatric Cardiology, Medical University of South Carolina, Charleston, SC, USA
Open Biomed Eng J 1:47-52. 2007..Higher temperatures coupled with lower treatment times result in reduced effects of perfusion on MW ablation... - Finite-element analysis of hepatic multiple probe radio-frequency ablationDieter Haemmerich
Department of Surgery, University of Wisconsin, Madison 53792, USA
IEEE Trans Biomed Eng 49:836-42. 2002..The monopolar mode showed the worst performance since the two probes in close vicinity create a disadvantageous electric field configuration. We, thus, conclude that alternating monopolar RF ablation is superior to the other two methods... - Error analysis of tissue resistivity measurementJang-Zern Tsai
Department of Electrical and Computer Engineering, University of Wisconsin, MadisonI 53706 USA
IEEE Trans Biomed Eng 49:484-94. 2002..61% error. We combined the above errors to yield an overall standard deviation error of the measured tissue resistivity of +/- 1.96%... - Multiple probe radiofrequency ablation: pilot study in an animal modelFred T Lee
Department of Radiology, University of Wisconsin Hospital and Clinics, 600 Highland Avenue, Madison, WI 53792, USA
J Vasc Interv Radiol 14:1437-42. 2003.... - Theoretical analysis of the heat convection coefficient in large vessels and the significance for thermal ablative therapiesLuisa Consiglieri
Department of Mathematics and CMAF, University of Lisboa, Av Prof Gama Pinto 2, 1649-003 Lisboa, Portugal
Phys Med Biol 48:4125-34. 2003..The results show that heating a larger portion of the vessels reduces convective heat loss, which may result in more effective ablation strategies... - Three-Dimensional finite-element analyses for radio-frequency hepatic tumor ablationSupan Tungjitkusolmun
Department of Electronics Engineering, King Mongkut's Institute of Technology Ladkrabang, Bangkok, Thailand
IEEE Trans Biomed Eng 49:3-9. 2002..The temperature distribution in the 2-D model was highly nonuniform due to the presence of the bifurcated blood vessel. Underdosed areas might be present next to the blood vessel from which the tumor can regenerate... - Modeling bipolar phase-shifted multielectrode catheter ablationSupan Tungjitkusolmun
Department of Electronics Engineering, King Mongkut's Institute of Technology Ladkrabang, Bangkok, Thailand
IEEE Trans Biomed Eng 49:10-7. 2002..5 degrees to 23.5 degrees, and in the vicinity of 26.5 degrees, respectively. The optimal phi for 3-mm spacing MEC was 30.5 degrees. We show the design of a simplified bipolar phase-shifted MEC ablation system... - Hepatic radiofrequency ablation with internally cooled probes: effect of coolant temperature on lesion sizeDieter Haemmerich
Department of Surgery, University of Wisconsin, Madison, WI 53792, USA
IEEE Trans Biomed Eng 50:493-500. 2003..Water temperature did not have a significant effect on lesion size in the ex vivo experiments (p = 0.76), the FEM model, and the analytical solution... - Letter by Saul and Haemmerich regarding article "Comparison of electrode cooling between internal and open irrigation in radiofrequency ablation lesion depth and incidence of thrombus and steam pop"J Philip Saul
Circulation 113:e936; author reply e937. 2006 - Large-volume radiofrequency ablation of ex vivo bovine liver with multiple cooled cluster electrodesDieter Haemmerich
Department of Biomedical Engineering, University of Wisconsin, Madison, USA
Radiology 234:563-8. 2005..Rapid switching created large round lesions by employing multiple electrodes concurrently, which substantially reduced treatment time and resulted in more effective heating between electrodes... - Multiple-electrode radiofrequency ablation: simultaneous production of separate zones of coagulation in an in vivo porcine liver modelPaul F Laeseke
Department of Radiology, University of Wisconsin, Madison 53792-3252, USA
J Vasc Interv Radiol 16:1727-35. 2005..This system would allow physicians to simultaneously treat multiple tumors, substantially reducing procedure time and anesthesia risk... - Lesion size estimator of cardiac radiofrequency ablation at different common locations with different tip temperaturesYu-Chi Lai
Department of Electrical and Computer Engineering, University of Wisconsin, Madison, WI 53706, USA
IEEE Trans Biomed Eng 51:1859-64. 2004..Based on the database, the software estimated lesion dimensions during different applied durations. This software could be used as a first-step predictor to help the electrophysiologist choose treatment parameters... - Multiple-electrode radiofrequency ablation creates confluent areas of necrosis: in vivo porcine liver resultsPaul F Laeseke
Department of Radiology, University of Wisconsin, Box 3252, Clinical Science Center E3, 600 Highland Ave, Madison, WI 53792, USA
Radiology 241:116-24. 2006..To prospectively evaluate, in vivo in pigs, an impedance-based multiple-electrode radiofrequency (RF) ablation system for creation of confluent areas of hepatic coagulation... - In-vivo measurement of swine myocardial resistivityJang-Zern Tsai
Department of Electrical and Computer Engineering, University of Wisconsin, Madison 53706 USA
IEEE Trans Biomed Eng 49:472-83. 2002..There was no significant difference in the myocardial resistivity measured at different sites... - Effects of the time response of the temperature sensor on thermodilution measurementsAdson F da Rocha
Department of Electrical Engineering, University of Brasilia, DF 70910-900, Brazil
Physiol Meas 26:885-901. 2005..The results show that these small errors appear during arrhythmias that affect the R-R interval and when the real temperature distribution at the pulmonary artery does not possess a shape with perfect temperature plateaux... - Mechanical compliance of the endocardiumYoung Bin Choy
Department of Electrical and Computer Engineering, University of Illinois, Urbana, IL 61801, USA
J Biomech 35:1671-6. 2002..The force increased by a factor of 5 for the mitral valve annulus and 8 for the left free wall from 15 min to 18 h. We derived coefficients of a second-order polynomial equation relating the force data to insertion depth with R(2)>0.99... - Haemostatic partial nephrectomy using bipolar radiofrequency ablationGyan Pareek
Department of Surgery Division of Urology, University of Wisconsin Medical School, 600 Highland Avenue, Madison, WI 53792, USA
BJU Int 96:1101-4. 2005..To determine whether an electrode array with a bipolar radiofrequency ablation (RFA) energy source can be used to perform a haemostatic partial nephrectomy by simultaneously ablating and coagulating renal tissue... - In vivo electrical conductivity of hepatic tumoursDieter Haemmerich
Department of Surgery, University of Wisconsin Madison, 600 Highland Avenue, WI 53792, USA
Physiol Meas 24:251-60. 2003..05). We conclude that necrosis within the tumour and the associated membrane breakdown is likely responsible for the observed change in conductivity... - Technologies for guidance of radiofrequency ablation in the multimodality interventional suite of the futureBradford J Wood
Diagnostic Radiology Department, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA
J Vasc Interv Radiol 18:9-24. 2007..Much of this new technology is in use or will be available to the interventional radiologist in the near future, and this brief introduction will hopefully encourage research in this emerging area... - Hepatic resection but not radiofrequency ablation results in tumor growth and increased growth factor expressionKenneth Meredith
Department of Surgery, University of Wisconsin, 600 Highlands Avenue, Madison, WI 53792, USA
Ann Surg 245:771-6. 2007..The purpose of this study was to examine the effects of radiofrequency ablation (RFA) on tumor growth and growth factor expression in a murine model... - Current status of liver tumor ablation devicesAnn P O'Rourke
Department of Surgery, University of Wisconsin, Madison, WI 53792, USA
Expert Rev Med Devices 4:523-37. 2007..It focuses on probe design for radiofrequency ablation, microwave ablation and cryoablation, and compares the advantages and disadvantages of each ablation modality... - Bipolar radiofrequency ablation of the kidney: comparison with monopolar radiofrequency ablationStephen Y Nakada
Department of Surgery, Division of Urology, University of Wisconsin Medical School, G5 339 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792 3236, USA
J Endourol 17:927-33. 2003..An internal ground electrode is positioned in the kidney opposite the RF electrode, resulting in ablation of all the intervening renal tissue...
Research Grants
- Prevention of Ground Pad During Radiofrequency Tumor AblationDieter Haemmerich; Fiscal Year: 2007..Physicians will be able to treat larger tumors, treatment times will be reduced, and success rates may increase. ..
- Prevention of Ground Pad During Radiofrequency Tumor AblationDieter Haemmerich; Fiscal Year: 2009..Physicians will be able to treat larger tumors, treatment times will be reduced, and success rates may increase. ..
- Prevention of Ground Pad During Radiofrequency Tumor AblationDieter Haemmerich; Fiscal Year: 2010..Physicians will be able to treat larger tumors, treatment times will be reduced, and success rates may increase. ..