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Genomes and GenesSpecies | Brian K McFarlinSummaryCountry: USA Publications
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Publications
TLR4 is lower in resistance-trained older women and related to inflammatory cytokinesBrian K McFarlin
Laboratory of Integrated Physiology, Department of Health and Human Performance corrected University of Houston, Houston, TX, USA
Med Sci Sports Exerc 36:1876-83. 2004..Therefore, the purpose of the present study was to compare the effect of acute (3 sets, 9 exercises, 10 repetitions at 80% of the 1-repetition maximum) and chronic resistance exercise on TLR4 and inflammatory cytokines...
Repeated endurance exercise affects leukocyte number but not NK cell activityBrian K McFarlin
Texas Christian University, Department of Kinesiology, Fort Worth, TX, USA
Med Sci Sports Exerc 35:1130-8. 2003..The purpose of this study was to determine the affects of repeated bouts of exercise in the same day on circulating leukocyte number and NK cell activity (NKCA)...
Exercise in hot and cold environments: differential effects on leukocyte number and NK cell activityBrian K McFarlin
Department of Kinesiology, Texas Christian University, Fort Worth, TX 76129, USA
Aviat Space Environ Med 74:1231-6. 2003..Therefore, the purpose was to examine the immune responses following exercise combined with exposure to hot and cold environments...
Relation between adiposity and disease risk factors in Mexican American childrenBrian K McFarlin
Department of Health and Human Performance, Laboratory of Integrated Physiology, University of Houston, Houston, TX 77204 6015, USA
J Pediatr Gastroenterol Nutr 49:450-5. 2009..The purpose of this study was to examine the relation between measures of adiposity and disease risk factors in Mexican American children participating in a weight loss intervention...
Effects of a school-based weight maintenance program for Mexican-American children: results at 2 yearsCraig A Johnston
Baylor College of Medicine, USDA ARS Children s Nutrition Research Center, Department of Pediatrics Nutrition, Houston, Texas, USA
Obesity (Silver Spring) 18:542-7. 2010..35, P < 0.05) compared to children in the SH condition. Overall, the school-based intervention resulted in improved weight and clinical outcomes in overweight Mexican-American children, and zBMI was maintained over 2 years...
The influence of exercise training on inflammatory cytokines and C-reactive proteinLaura K Stewart
Department of Kinesiology, Louisiana State University, Baton Rouge, LA 70803 2401, USA
Med Sci Sports Exerc 39:1714-9. 2007..A secondary purpose was to determine whether training-induced changes in cytokines and CRP were influenced by age...
Aerobic fitness is associated with lower proportions of senescent blood T-cells in manGuillaume Spielmann
Laboratory of Integrated Physiology, Department of Health and Human Performance, University of Houston, 3855 Holman Street, Houston, TX 77204, USA
Brain Behav Immun 25:1521-9. 2011..This is the first study to show that aerobic fitness is associated with a lower age-related accumulation of senescent T-cells, highlighting the beneficial effects of maintaining a physically active lifestyle on the aging immune system...
Generalized equations for estimating DXA percent fat of diverse young women and men: the TIGER studyDaniel P O'Connor
Texas Obesity Research Center, Houston, TX, USA
Med Sci Sports Exerc 42:1959-65. 2010..We developed accurate anthropometric models to estimate dual-energy x-ray absorptiometry BF% (DXA-BF%) that can be generalized to ethnically diverse young adults in both cross-sectional and longitudinal field settings...
Ethnic bias in anthropometric estimates of DXA abdominal fat: the TIGER studyDaniel P O'Connor
Texas Obesity Research Center, Department of Health and Human Performance, University of Houston, Houston, TX, USA
Med Sci Sports Exerc 43:1785-90. 2011..BACKGROUND/INTRODUCTION: The purpose of this study was to examine the race/ethnicity bias of using waist circumference (WC) to estimate abdominal fat...
Development of an online university-based Physical Activity and Obesity education programBrian K McFarlin
University of Houston, Department of Health and Human Performance, 3855 Holman Street, 104U Garrison, Houston, Texas 77204 6015, USA
Diabetes Educ 34:766, 770, 772-4 passim. 2008..The purpose of this article is to describe the development and implementation of an undergraduate university core course titled, Public Health Issues in Physical Activity and Obesity (KIN1304) at a diverse, urban university...
Physical activity status, but not age, influences inflammatory biomarkers and toll-like receptor 4Brian K McFarlin
Department of Health and Human Performance, University of Houston, 3855 Holman St, Houston, Texas 77204, USA
J Gerontol A Biol Sci Med Sci 61:388-93. 2006..Therefore, the purpose of this study was to determine the association between age, physical activity status, biomarkers of inflammation, and TLR4...
Senescent phenotypes and telomere lengths of peripheral blood T-cells mobilized by acute exercise in humansRichard J Simpson
Laboratory of Integrated Physiology, Department of Health and Human Performance, University of Houston, 3855 Holman Street, Houston, Texas 77204, USA
Exerc Immunol Rev 16:40-55. 2010..We postulate that a frequent mobilization of these cells by acute exercise might eventually allow naïve T-cells to occupy the "vacant" immune space and increase the naïve T-cell repertoire...
Cross-validation of generalised body composition equations with diverse young men and women: the Training Intervention and Genetics of Exercise Response (TIGER) StudyAndrew S Jackson
University of Houston, Department of Health and Human Performance, 3855 Holman Street, Houston, TX 77204 6015, USA
Br J Nutr 101:871-8. 2009....
Knowledge of carbohydrate consumption does not alter natural killer cell activity following an acute bout of high-intensity aerobic exerciseBrian K McFarlin
Department of Health and Human Performance, Laboratory of Integrated Physiology, University of Houston, Houston, TX 77204 6015, USA
Appl Physiol Nutr Metab 33:1007-12. 2008..There was a significant effect of exercise on NKCA. Knowledge of drink type does not alter innate immunity following exercise as assessed by leukocyte counts and NKCA...
Weight loss in overweight Mexican American children: a randomized, controlled trialCraig A Johnston
Department of Pediatrics Nutrition, Children s Nutrition Research Center, Baylor College of Medicine, Houston, TX 77030, USA
Pediatrics 120:e1450-7. 2007..We hypothesized that children randomly assigned to an intensive intervention would significantly reduce their standardized BMI when compared with children randomly assigned to a self-help condition...
Toll-like receptor expression on classic and pro-inflammatory blood monocytes after acute exercise in humansRichard J Simpson
Laboratory of Integrated Physiology, Department of Health and Human Performance, University of Houston, 3855 Holman Street, Houston, TX 77204, USA
Brain Behav Immun 23:232-9. 2009..DR expression within specific blood monocyte subpopulations, and could therefore be occurring at the cellular level. Such alterations might have significant implications for modulation of post-exercise immune surveillance...
Resistance training at eight-repetition maximum reduces the inflammatory milieu in elderly womenMelody D Phillips
Texas Christian University, Exercise Physiology Laboratory, Fort Worth, TX 76123, USA
Med Sci Sports Exerc 42:314-25. 2010....
Pomegranate seed oil consumption during a period of high-fat feeding reduces weight gain and reduces type 2 diabetes risk in CD-1 miceBrian K McFarlin
Laboratory of Integrated Physiology, Department of Health and Human Performance, University of Houston, 3855 Holman Street, 104U Garrison, Houston, TX 77204 6015, USA
Br J Nutr 102:54-9. 2009..POMo intake was associated with an improvement in insulin sensitivity, suggesting that risk of developing type 2 diabetes may have been reduced; however, CVD risk did not change...
Severely obese have greater LPS-stimulated TNF-alpha production than normal weight African-American womenMichael L Kueht
Department of Health and Human Performance, University of Houston, Houston, Texas, USA
Obesity (Silver Spring) 17:447-51. 2009..This is one of the first studies to focus on African-American women, who have higher rates of obesity...
Energy restriction with different protein quantities and source: implications for innate immunityBrian K McFarlin
Department of Health and Human Performance, University of Houston, 104U Garrison, Houston, TX 77204 6015, USA
Obesity (Silver Spring) 14:1211-8. 2006....
Effect of exercise, heat stress, and hydration on immune cell number and functionJoel B Mitchell
Exercise Physiology Laboratory, Department of Kinesiology, Texas Christian University, Fort Worth, TX, USA
Med Sci Sports Exerc 34:1941-50. 2002..The purpose of this study was to determine the effect of thermal stress and hydration status on immune function during exercise...
Weight gain in response to high-fat feeding in CD-1 male miceW L Breslin
Laboratory of Integrated Physiology, Department of Health and Human Performance, University of Houston, Houston, TX 77004 6016, USA
Lab Anim 44:231-7. 2010..Our key findings characterize the issues related to and affecting experimental design when utilizing an outbred mouse diet-induced weight gain model and will serve as a guide for future researchers...
Exercise-induced immune cell apoptosis: image-based model for morphological assessmentJames W Navalta
Department of Kinesiology, Recreation, and Sport, Western Kentucky University, Bowling Green, KY 42101 1089, USA
Eur J Appl Physiol 110:325-31. 2010....
Inflammatory markers are elevated in overweight Mexican-American childrenBrian K McFarlin
Department of Health and Human Performance, Laboratory of Integrated Physiology University of Houston, Houston, Texas, 77204 6015, USA
Int J Pediatr Obes 2:235-41. 2007..The purpose of the present study was to determine the effect of body weight on blood lipid profile, insulin resistance and inflammatory biomarkers in Mexican-American children...
Carbohydrate consumption during cycling increases in vitro NK cell responses to IL-2 and IFN-gammaBrian K McFarlin
University of Houston, Department of Health and Human Performance, Laboratory of Integrated Physiology, Houston, TX 77204 6015, USA
Brain Behav Immun 21:202-8. 2007..As a follow-up to our previous research, the purpose of this study was to examine the T and NK cells responses during and following moderate/high-intensity endurance exercise...
Influence of obesity, physical inactivity, and weight cycling on chronic inflammationK Strohacker
Laboratory of Integrated Physiology, Department of Health and Human Performance, University of Houston, Houston, Texas 77204 6015, USA
Front Biosci (Elite Ed) 2:98-104. 2010..The purpose of this review is to explore inflammatory consequences associated with weight cycling as they are related to sustained weight gain, obesity, physical inactivity as well as relative disease risk...
Immune responses to exercising in a cold environmentEmily C P Lavoy
Laboratory of Integrated Physiology, Department of Health and Human Performance, University of Houston, Houston, Texas 77204 6015, USA
Wilderness Environ Med 22:343-51. 2011..This is required to fully determine the extent to which performing vigorous exercise in subfreezing temperatures amplifies exercise-induced immune impairment and infection risk...
Hybrid lecture-online format increases student grades in an undergraduate exercise physiology course at a large urban universityBrian K McFarlin
Laboratory of Integrated Physiology, Department of Health and Human Performance, and Texas Obesity Research Center, University of Houston, Houston, Texas 77204 6015, USA
Adv Physiol Educ 32:86-91. 2008....
Toll-like receptor 4: link to the anti-inflammatory effects of exercise?Michael G Flynn
Wastl Human Performance Laboratory, Department of Health and Kinesiology, Purdue University, West Lafayette, IN 47907, USA
Exerc Sport Sci Rev 34:176-81. 2006..The toll-like receptor 4 expression was consistently lower in physically active subjects compared with inactive subjects and reduced after training in previously inactive subjects...
Chronic resistance exercise training improves natural killer cell activity in older womenBrian K McFarlin
Department of Health and Human Performance, University of Houston, Texas 77204 6015, USA
J Gerontol A Biol Sci Med Sci 60:1315-8. 2005..To evaluate this response, we recruited older, postmenopausal women (65-85 years old) to fill one of two groups: training (10 weeks of resistance exercise; TR) or control...
Influence of exercise training and age on CD14+ cell-surface expression of toll-like receptor 2 and 4Laura K Stewart
Wastl Human Performance Laboratory, Department of Health and Kinesiology, Purdue University, West Lafayette, IN 47907, USA
Brain Behav Immun 19:389-97. 2005..An exercise training program reduced LPS-stimulated IL-6, concomitant with lower TLR4. These results provide further support for a training- or physical activity-induced lowering of TLR4 and inflammation...
Carbohydrate intake during endurance exercise increases natural killer cell responsiveness to IL-2Brian K McFarlin
Wastl Human Performance Laboratory, Department of Health and Kinesiology, Purdue University, West Lafayette, IN 47905, USA
J Appl Physiol 96:271-5. 2004..NKCA was significantly lower 2H (NKCA-51, NKCA-69) and 4H (NKCA-69) than Pre. CHO consumption during exercise did not prevent disruptions in unstimulated immune system function, but it did enhance NK responsiveness to IL-2...
Toll-like receptor 4 and CD14 mRNA expression are lower in resistive exercise-trained elderly womenMichael G Flynn
Dept of Health and Kinesiology, Wastl Human Performance Laboratory, Purdue University, West Lafayette, Indiana 47906, USA
J Appl Physiol 95:1833-42. 2003..Further research is needed to determine whether lower TLR4/CD14 could explain the lower LPS-stimulated inflammatory cytokines observed in these women...
Protein intake during energy restriction: effects on body composition and markers of metabolic and cardiovascular health in postmenopausal womenAnne K Mahon
Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907 2059, USA
J Am Coll Nutr 26:182-9. 2007..The primary aim of this study was to assess the effects of dietary protein intake on energy restriction (ER)-induced changes in body mass and body composition. Clinical markers of metabolic and cardiovascular diseases were also measured...
Neither gender nor menstrual cycle phase influences exercise-induced lymphocyte apoptosis in untrained subjectsJames W Navalta
Department of Physical Education and Recreation, 1906 College Heights Blvd 11089, Bowling Green, KY 42101 1089, USA
Appl Physiol Nutr Metab 32:481-6. 2007..7%+/-0.9%, ML=22.7%+/-1.1%). Although elevated female sex hormones in vitro may exert anti-apoptotic effects, these data suggest that in vivo concentrations confer no protection to lymphocytes during exhaustive exercise...
