Research Topics
Species | Prashanthi VemuriSummaryAffiliation: Mayo Clinic Country: USA Publications
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Detail Information
Publications
Brain beta-amyloid measures and magnetic resonance imaging atrophy both predict time-to-progression from mild cognitive impairment to Alzheimer's diseaseClifford R Jack
Department of Radiology, Mayo Clinic and Foundation, 200 First Street SW, Rochester, MN 55905, USA
Brain 133:3336-48. 2010....- Resting state functional MRI in Alzheimer's DiseasePrashanthi Vemuri
Department of Radiology, Mayo Clinic and Foundation, 200 First Street SW, Rochester, MN 55905, USA
Alzheimers Res Ther 4:2. 2012..Then we present the current state of knowledge in this area by summarizing various AD resting-state fMRI studies presented in the first section and end with a discussion of future developments and open questions in the field... - Antemortem differential diagnosis of dementia pathology using structural MRI: Differential-STANDPrashanthi Vemuri
Department of Radiology, Mayo Clinic and Foundation, Rochester, MN 55905, USA
Neuroimage 55:522-31. 2011..8%). The proposed approach establishes a direct a priori relationship between specific topographic patterns on MRI and "gold standard" of pathology which can then be used to predict underlying dementia pathology in new incoming patients... - Cognitive reserve and Alzheimer's disease biomarkers are independent determinants of cognitionPrashanthi Vemuri
Department of Radiology, Mayo Clinic and Foundation, 200 First Street SW, Rochester, MN 55905, USA
Brain 134:1479-92. 2011.... - Role of structural MRI in Alzheimer's diseasePrashanthi Vemuri
Aging and Dementia Imaging Research Laboratory, Department of Radiology, Mayo Clinic and Foundation, 200 First Street SW, Rochester, MN 55905, USA
Alzheimers Res Ther 2:23. 2010.... - Evidence for ordering of Alzheimer disease biomarkersClifford R Jack
Department of Radiology, Mayo Clinic and Mayo Foundation for Medical Education and Research, 200 First St, SW, Rochester, MN 55905, USA
Arch Neurol 68:1526-35. 2011..To empirically assess the concept that Alzheimer disease (AD) biomarkers significantly depart from normality in a temporally ordered manner... - Effect of apolipoprotein E on biomarkers of amyloid load and neuronal pathology in Alzheimer diseasePrashanthi Vemuri
Aging and Dementia Imaging Research Laboratory, Department of Radiology, Mayo Clinic and Foundation, 200 First Street SW, Rochester, MN 55905, USA
Ann Neurol 67:308-16. 2010.... - Time-to-event voxel-based techniques to assess regional atrophy associated with MCI risk of progression to ADPrashanthi Vemuri
Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA
Neuroimage 54:985-91. 2011..We also compared the power required to detect an association using time-to-event methods versus two-sample approaches... - Transforming cerebrospinal fluid A?42 measures into calculated Pittsburgh Compound B units of brain A? amyloidStephen D Weigand
Division of Biomedical Statistics and Informatics, Mayo Clinic and Foundation, Rochester, MN, USA
Alzheimers Dement 7:133-41. 2011..The objectives of this study were to develop a method to transform CSF A?42 measures into calculated PIB measures (PIBcalc) of A? amyloid load, and to partially validate the method in an independent sample of subjects... - Effect of APOE ?4 status on intrinsic network connectivity in cognitively normal elderly subjectsMary M Machulda
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
Arch Neurol 68:1131-6. 2011..To examine default mode and salience network functional connectivity as a function of APOE ?4 status in a group of cognitively normal age-, sex-, and education-matched older adults... - Alzheimer's disease diagnosis in individual subjects using structural MR images: validation studiesPrashanthi Vemuri
Department of Radiology, Mayo Clinic 200 1st St SW, Rochester, MN 55905, USA
Neuroimage 39:1186-97. 2008..To develop and validate a tool for Alzheimer's disease (AD) diagnosis in individual subjects using support vector machine (SVM)-based classification of structural MR (sMR) images... - Distinct anatomical subtypes of the behavioural variant of frontotemporal dementia: a cluster analysis studyJennifer L Whitwell
Department of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Brain 132:2932-46. 2009..Our findings suggest behavioural variant of frontotemporal dementia can therefore be subdivided into four different anatomical subtypes... - Antemortem MRI based STructural Abnormality iNDex (STAND)-scores correlate with postmortem Braak neurofibrillary tangle stagePrashanthi Vemuri
Department of Radiology, Mayo Clinic Rochester, Rochester, MN 55905, USA
Neuroimage 42:559-67. 2008.... - Disrupted thalamocortical connectivity in PSP: a resting-state fMRI, DTI, and VBM studyJennifer L Whitwell
Department of Radiology, Mayo Clinic, 200 1st Street SW, Rochester, MN 55905, USA
Parkinsonism Relat Disord 17:599-605. 2011..PSP is therefore associated with disrupted thalamocortical connectivity that is associated with degeneration of the dentatorubrothalamic tract and the presence of cortical atrophy... - Characterization of frontotemporal dementia and/or amyotrophic lateral sclerosis associated with the GGGGCC repeat expansion in C9ORF72Bradley F Boeve
Mayo Clinic, Department of Neurology, 200 First Street SW, Rochester, MN 55905, USA
Brain 135:765-83. 2012..While variability exists, most cases with this mutation have a characteristic spectrum of demographic, clinical, neuropsychological, neuroimaging and especially neuropathological findings... - Assessing subtle structural changes in Alzheimer's disease patientsJennifer L Whitwell
Department of Radiology, Mayo Clinic, Rochester, MN, USA
Methods Mol Biol 711:535-50. 2011.... - Mild cognitive impairment: baseline and longitudinal structural MR imaging measures improve predictive prognosisLinda K McEvoy
Department of Radiology, University of California, San Diego, 9500 Gilman Dr, La Jolla, CA 92093, USA
Radiology 259:834-43. 2011..To assess whether single-time-point and longitudinal volumetric magnetic resonance (MR) imaging measures provide predictive prognostic information in patients with amnestic mild cognitive impairment (MCI)...