Research Topics
| G A NuttallSummaryAffiliation: Mayo Clinic Country: USA Publications
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Publications
Does low-dose droperidol administration increase the risk of drug-induced QT prolongation and torsade de pointes in the general surgical population?Gregory A Nuttall
Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Anesthesiology 107:531-6. 2007..The US Food and Drug Administration issued a black box warning regarding the use of droperidol and the potential for torsade de pointes (TdP)...- Con: use of colloids in cardiac surgeryGregory A Nuttall
Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
J Cardiothorac Vasc Anesth 21:457-9. 2007 - A prospective, randomized platelet-function study of heparinized oxygenators and cardiotomy suctionGregory A Nuttall
Department of Surgery, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
J Cardiothorac Vasc Anesth 20:554-61. 2006..The purpose of this study was to determine if substitution of a heparin-coated oxygenator and salvaged autologous blood for cardiotomy suction would improve platelet function... - Time and cardiac risk of surgery after bare-metal stent percutaneous coronary interventionGregory A Nuttall
Department of Anesthesiology, Mayo Clinic, 200 First Street Southwest, Rochester, Minnesota 55905, USA
Anesthesiology 109:588-95. 2008..The duration of time that elective noncardiac surgery (NCS) should be delayed after percutaneous coronary intervention (PCI) with bare metal stents (BMSs) is unknown... - Current transfusion practices of members of the american society of anesthesiologists: a surveyGregory A Nuttall
Division of Biostatistics, Mayo Clinic, Rochester, Minnesota 55905, USA
Anesthesiology 99:1433-43. 2003..The last published survey of transfusion practices among members of the American Society of Anesthesiologists (ASA) was conducted in 1981. The ASA Committee on Transfusion Medicine conducted a new transfusion survey in 2002... - A comparison of bleeding and transfusion in patients who undergo coronary artery bypass grafting via sternotomy with and without cardiopulmonary bypassGregory A Nuttall
Department of Anesthesiology and Cardiac Surgery, Mayo School of Health Sciences, Mayo Clinic, Rochester, MN 55905, USA
J Cardiothorac Vasc Anesth 17:447-51. 2003.... - Excessive bleeding and transfusion in a prior cardiac surgery is associated with excessive bleeding and transfusion in the next surgeryGregory A Nuttall
Department of Anesthesilogy, Mayo Clinic, Rochester, Minnesota 55905, USA
Anesth Analg 102:1012-7. 2006..We conclude that a history of excessive bleeding during the first operation is associated with more than two times increased risk for excessive bleeding in the second surgery... - Radical retropubic prostatectomy and blood transfusionGregory A Nuttall
Department of Anesthesiology, Mayo Clinic, Rochester, Minn 55905, USA
Mayo Clin Proc 77:1301-5. 2002.... - Risk factors for ischemic optic neuropathy after cardiopulmonary bypass: a matched case/control studyG A Nuttall
Department of Anesthesiology, Mayo Graduate School of Medicine, Rochester, Minnesota 55905, USA
Anesth Analg 93:1410-6, table of contents. 2001.... - Comparison of blood-conservation strategies in cardiac surgery patients at high risk for bleedingG A Nuttall
Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota 55905, USA
Anesthesiology 92:674-82. 2000..Aprotinin and tranexamic acid are routinely used to reduce bleeding in cardiac surgery. There is a large difference in agent price and perhaps in efficacy... - Efficacy of a simple intraoperative transfusion algorithm for nonerythrocyte component utilization after cardiopulmonary bypassG A Nuttall
Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota 55905, USA
Anesthesiology 94:773-81; discussion 5A-6A. 2001..Coagulation test-based algorithms may reduce transfusion of non-erythrocyte allogeneic blood in patients with abnormal bleeding... - Predictors of blood transfusions in spinal instrumentation and fusion surgeryG A Nuttall
Departments of Anesthesiology, Laboratory Medicine, Orthopedic Surgery, and Statistics, Mayo Clinic, Rochester, Minnesota 55905, USA
Spine (Phila Pa 1976) 25:596-601. 2000..A retrospective review of 244 adult spine instrumentation and fusion surgery cases (1994-1995) from one institution... - Use of the surgical blood order equation in spinal instrumentation and fusion surgeryG A Nuttall
Departments of Anesthesiology, Laboratory Medicine, Orthopedic Surgery, and Statistics, Mayo Clinic, Rochester, Minnesota 55905, USA
Spine (Phila Pa 1976) 25:602-5. 2000..A retrospective review of 182 cases of adult spine instrumentation and fusion surgery (1994-1995) from one institution... - Does the platelet-activated clotting test (HemoSTATUS) predict blood loss and platelet dysfunction associated with cardiopulmonary bypass?M H Ereth
Department of Anesthesiology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
Anesth Analg 85:259-64. 1997..The PACT may be a useful indicator of platelet responsiveness or whole blood procoagulant activity, but we did not find it superior to other tests of coagulation function for predicting excessive blood loss after CPB... - Platelet glass bead retention predicts bleeding after cardiac surgeryM H Ereth
Department of Anesthesiology, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
J Cardiothorac Vasc Anesth 15:49-54. 2001..Modification of this platelet function assay used with the prothrombin time may provide a simple and effective diagnostic approach to bleeding after CPB... - A prospective, randomized study of cardiopulmonary bypass temperature and blood transfusionP E Stensrud
Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota 55905, USA
Ann Thorac Surg 67:711-5. 1999..We hypothesized that normothermic cardiopulmonary bypass (CPB) would be associated with decreased blood loss and allogeneic transfusion requirements relative to hypothermic CPB... - The relation between the platelet-activated clotting test (HemoSTATUS) and blood loss after cardiopulmonary bypassM H Ereth
Department of Anesthesiology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
Anesthesiology 88:962-9. 1998.... - Normothermic cardiopulmonary bypass increases heparin requirements necessary to maintain anticoagulationM H Ereth
Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905, USA
J Clin Monit Comput 14:323-7. 1998..CPB temperature predictability affects pharmacokinetics and differences in drug metabolism can be expected. We hypothesized that heparin requirements would increase with increasing CPB temperature... - Desmopressin does not reduce bleeding and transfusion requirements in congenital heart operationsW C Oliver
Department of Anesthesiology, Mayo Foundation, Rochester, Minnesota 55905, USA
Ann Thorac Surg 70:1923-30. 2000..Desmopressin reduces blood loss in adult patients with excessive bleeding after cardiac operation. Its usefulness in patients undergoing complex congenital heart repair with cardiopulmonary bypass is unproved... - Plasma tranexamic acid concentrations during cardiopulmonary bypassB K Fiechtner
Mayo Clinic and Graduate School of Medicine, Rochester, MN 55905, USA
Anesth Analg 92:1131-6. 2001..kg(-1).h(-1)produced plasma concentrations throughout the cardiopulmonary bypass period sufficient to inhibit fibrinolysis in vitro. The dosing of tranexamic acid may require adjustment for renal insufficiency... - Biocompatibility of Trillium Biopassive Surface-coated oxygenator versus uncoated oxygenator during cardiopulmonary bypassM H Ereth
Department of Anesthesiology, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
J Cardiothorac Vasc Anesth 15:545-50; discussion 539-41. 2001..CONCLUSION: This human trial of Trillium Biopassive Surface-coated oxygenators did not show clinical benefits or clinically important biochemical results... - The accuracy of coagulation tests during spinal fusion and instrumentationT T Horlocker
Departments of Anesthesiology, Orthopedic Surgery, and Biostatistics, Mayo Clinic, Rochester, Minnesota 55905, USA
Anesth Analg 93:33-8. 2001..The test values that differentiated normal from excessively bleeding patients could be used to guide transfusion therapy during surgery... - Hemofiltration during cardiopulmonary bypass does not decrease the incidence of atrial fibrillation after cardiac surgeryWilliam J Mauermann
Department of Anesthesiology and Biostatistics, Mayo Clinic, Rochester, Minnesota, USA
Anesth Analg 110:329-34. 2010..We hypothesized that hemofiltration during CPB, which may attenuate inflammation, might decrease the incidence of AF after cardiac surgery... - Variability of plasma aprotinin concentrations in pediatric patients undergoing cardiac surgeryWilliam C Oliver
Department of Anesthesiology, Rochester, Minnesota 55905
J Thorac Cardiovasc Surg 127:1670-7. 2004..The aim of this study was to determine plasma aprotinin concentrations in these patients with a functional aprotinin assay... - Microporous Polysaccharide Hemospheres do not enhance abdominal infection in a rat model compared with gelatin matrixMark H Ereth
Transfusion, Coagulation and Cardiopulmonary Bypass Research Group, Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota 55905, USA
Surg Infect (Larchmt) 10:273-6. 2009..A newly approved agent, Microporous Polysaccharide Hemospheres (MPH) (Arista AH), has rapid degradation properties, which may reduce the chance of surgical site infection... - Comparative safety and efficacy of topical hemostatic agents in a rat neurosurgical modelMark H Ereth
Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Neurosurgery 63:369-72; discussion 372. 2008..This study compares the safety and efficacy of commonly used agents with a newly approved agent, Arista (microporous polysaccharide hemospheres; Medafor, Inc., Minneapolis, MN)... - Cardiac risk of noncardiac surgery after percutaneous coronary intervention with drug-eluting stentsJennifer A Rabbitts
Department of Anesthesiology, Mayo Clinic, 200 First Street Southwest, Rochester, Minnesota 55905, USA
Anesthesiology 109:596-604. 2008..The American College of Cardiology released a scientific advisory that included a recommendation to delay elective of noncardiac surgery (NCS) for 1 yr after percutaneous coronary intervention (PCI) with a drug-eluting stent (DES)... - Hemofiltration but not steroids results in earlier tracheal extubation following cardiopulmonary bypass: a prospective, randomized double-blind trialWilliam C Oliver
Mayo Medical School, Rochester, Minnesota, USA
Anesthesiology 101:327-39. 2004.... - A study of a weight-adjusted aprotinin dosing schedule during cardiac surgeryGregory A Nuttall
Department of Anesthesiology, Mayo Graduate School of Medicine, Rochester, Minnesota 55905, USA
Anesth Analg 94:283-9, table of contents. 2002..A new weight-based dosing schedule reduced variation of aprotinin concentration over time, but was unable to reduce between-patient variability in aprotinin concentration... - Accuracy of roche accu-chek inform whole blood capillary, arterial, and venous glucose values in patients receiving intensive intravenous insulin therapy after cardiac surgeryBrad S Karon
Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Am J Clin Pathol 127:919-26. 2007..Capillary whole blood glucose levels correlate most closely with laboratory plasma glucose levels in patients receiving intensive intravenous insulin therapy after cardiac surgery... - Intensive intraoperative insulin therapy versus conventional glucose management during cardiac surgery: a randomized trialGunjan Y Gandhi
Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Ann Intern Med 146:233-43. 2007..It is not known whether rigorous intraoperative glycemic control reduces death and morbidity in cardiac surgery patients... - A comparison of fenoldopam with dopamine and sodium nitroprusside in patients undergoing cross-clamping of the abdominal aortaWilliam C Oliver
Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Anesth Analg 103:833-40. 2006..Therefore, fenoldopam has no therapeutic advantage compared with similar therapies in patients undergoing major vascular surgery involving cross-clamping of the aorta... - Patients with a history of type II heparin-induced thrombocytopenia with thrombosis requiring cardiac surgery with cardiopulmonary bypass: a prospective observational case seriesGregory A Nuttall
Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota 55905, USA
Anesth Analg 96:344-50, table of contents. 2003..The patients receiving hirudin did well, but they had a large amount of bleeding, required transfusions of multiple allogeneic blood products, and had a frequent rate of reexploration of the mediastinum after CPB... - Blood loss in infants and children for open heart operations: albumin 5% versus fresh-frozen plasma in the primeWilliam C Oliver
Department of Anesthesiology, Mayo Foundation, Rochester, Minnesota 55905, USA
Ann Thorac Surg 75:1506-12. 2003..Fresh-frozen plasma has been included in the prime to lessen dilution of clotting factors and correspondingly minimize blood loss and transfusions... - Heparin-coated versus uncoated extracorporeal circuit in patients undergoing coronary artery bypass graft surgeryWilliam C Oliver
Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905, USA
J Cardiothorac Vasc Anesth 17:165-70. 2003..To assess the effect of heparin-coated circuits on bleeding, transfusion, and platelet count in patients undergoing primary coronary artery bypass grafting with full heparinization... - Intraoperative hyperglycemia and perioperative outcomes in cardiac surgery patientsGunjan Y Gandhi
Department of Internal Medicine and Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
Mayo Clin Proc 80:862-6. 2005..To estimate the magnitude of association between intraoperative hyperglycemia and perioperative outcomes in patients who underwent cardiac surgery... - Cardiopulmonary bypass support for percutaneous coronary interventions: what the anesthesiologist needs to knowChristopher M Burkle
Department of Anesthesiology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
J Cardiothorac Vasc Anesth 19:501-4. 2005 - The effect of in vitro recombinant factor VIIA on coagulation parameters for blood taken during liver transplantationB Gali
Anesthesiology Department, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Transplant Proc 37:4367-9. 2005..5 mm vs 39 mm, P < .02). No significant differences existed in the variables at any of the other sampling times. This study failed to demonstrate a consistent in vitro effect of rFVIIa on the blood taken from patients during OLT... - Effect of abciximab on the outcome of emergency coronary artery bypass grafting after failed percutaneous coronary interventionM Singh
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minn 55905, USA
Mayo Clin Proc 76:784-8. 2001..However, in-hospital adverse events are infrequent and comparable to those for patients who do not receive abciximab... - The effect of epsilon-aminocaproic acid and aprotinin on fibrinolysis and blood loss in patients undergoing primary, isolated coronary artery bypass surgery: a randomized, double-blind, placebo-controlled, noninferiority trialPhilip E Greilich
Department of Anesthesiology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA
Anesth Analg 109:15-24. 2009..We undertook this study to test the hypothesis that EACA, when dosed appropriately, is not inferior to aprotinin at reducing fibrinolysis and blood loss... - Aprotinin does not prolong the Sonoclot aprotinin-insensitive activated clotting timeYue Dong
Transfusion, Coagulation and Cardiopulmonary Bypass Research Group, Department of Anesthesiology, Mayo Clinic College of Medicine Rochester, MN 55905, USA
J Clin Anesth 19:424-8. 2007..To determine whether a new Sonoclot-based, aprotinin-insensitive activated clotting time (aiACT) assay yields stable results over a broad range of aprotinin concentrations... - An in vitro study comparing the effects of Hextend, Hespan, normal saline, and lactated ringer's solution on thrombelastography and the activated partial thromboplastin timeStephen E Dailey
Mayo School of Health Sciences, Rochester, MN 55905, USA
J Cardiothorac Vasc Anesth 19:358-61. 2005..562). CONCLUSIONS: This prospective in vitro study suggests that Hextend and Hespan, hydroxyethyl starch 450/0.7 in different base solutions, exhibit the same effect on platelet function as measured by the TEG... - A preliminary study of a new tranexamic acid dosing schedule for cardiac surgeryGregory A Nuttall
Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, MN, USA
J Cardiothorac Vasc Anesth 22:230-5. 2008.... - Mayo Clinic and the origins of blood bankingJennifer A Rabbitts
Department of Anesthesiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Mayo Clin Proc 82:1117-8. 2007 - A prospective study on anesthesia machine fault identificationEric R Larson
Department of Anesthesiology, Mayo College of Medicine, Rochester, Minnesota, USA
Anesth Analg 104:154-6. 2007..Although few studies have been performed recently, several have suggested that some practitioners are not well able to detect preset anesthesia machine faults... - Evidence-based red cell transfusion in the critically ill: quality improvement using computerized physician order entryRimki Rana
Family Medicine Residency, Mercy Medical Center-North Iowa, Mason City, IA, USA
Crit Care Med 34:1892-7. 2006..12; 95% confidence interval, 0.69 to 1.8). CONCLUSIONS: The implementation of an institutional protocol and decision support through a computerized provider order entry effectively decreased inappropriate red cell transfusions...