Research Topics
| T Jared BunchSummaryAffiliation: Mayo Clinic Country: USA Publications
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Publications
Progression of nonculprit plaque stenosis following successful percutaneous interventionT Jared Bunch
Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA
Angiology 59:236-9. 2008..This case report demonstrates the systemic nature of acute coronary syndromes, highlights the inherent instability of coronary artery disease, and supports the notion of aggressive secondary prevention in these patients...
Frequency of helicobacter pylori seropositivity and C-reactive protein increase in atrial fibrillation in patients undergoing coronary angiographyT Jared Bunch
Division of Cardiovascular Disease, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA
Am J Cardiol 101:848-51. 2008..Although older age was highly associated with AF risk in this population, H pylori was additive across 3 distinct age groups, with the highest risk conveyed in the younger cohort...
Catheter ablation for atrial fibrillation in patients with the Marfan and Marfan-like syndromesT Jared Bunch
Department of Internal Medicine, Mayo Clinic, Rochester, MN 55902, USA
J Interv Card Electrophysiol 20:15-20. 2007..In conclusion, catheter ablation of AF in patients with Marfan syndrome is a viable option in those individuals refractory to conventional therapy...
Trends in treated ventricular fibrillation in out-of-hospital cardiac arrest: ischemic compared to non-ischemic heart diseaseT Jared Bunch
Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic, College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
Resuscitation 67:51-4. 2005..The relative increasing incidence of non-ischemic VF OHCA suggests that more efforts are required to minimize mortality in this cohort population...
Three-dimensional ultrasound for image-guided mapping and intervention: methods, quantitative validation, and clinical feasibility of a novel multimodality image mapping systemYasuo Okumura
Translational Cardiac Electrophysiology Laboratory, Mayo Clinic, Rochester, Minn, USA
Circ Arrhythm Electrophysiol 1:110-9. 2008..Therefore, a Carto-based 3D ultrasound image system (Biosense Webster Inc) was validated in an animal model and tested in 15 atrial fibrillation patients...
A comparative analysis of short- and long-term outcomes after ventricular fibrillation out-of-hospital cardiac arrest in patients with ischemic and nonischemic heart diseaseT Jared Bunch
Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA
Am J Cardiol 98:857-60. 2006..Nonetheless, in patients with IHD, use of an implantable cardioverter-defibrillator and statin therapy were associated with higher long-term survival rates...
Long-term subjective memory function in ventricular fibrillation out-of-hospital cardiac arrest survivors resuscitated by early defibrillationT Jared Bunch
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA
Resuscitation 60:189-95. 2004..There were more long-term-memory complaints in younger patients. Patients with higher long-term quality-of-life score have fewer memory complaints...
Atrial fibrillation and CHADS2 risk factors are associated with highly sensitive C-reactive protein incrementally and independentlyMark A Crandall
Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA
Pacing Clin Electrophysiol 32:648-52. 2009..Similarly, it is unclear if inflammatory markers are elevated due to the AF alone or the coexisting cardiovascular diseases that increase the risk of AF...
Atrial fibrillation significantly increases total mortality and stroke risk beyond that conveyed by the CHADS2 risk factorsMark A Crandall
Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA
Pacing Clin Electrophysiol 32:981-6. 2009..Atrial fibrillation (AF) is associated with an increased risk of mortality and stroke. However, it is unclear if AF is independently associated with these poor outcomes or it is merely a risk marker of other processes that convey the risk...
Mechanisms of phrenic nerve injury during radiofrequency ablation at the pulmonary vein orificeT Jared Bunch
Division of Cardiovascular Disease, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA
J Cardiovasc Electrophysiol 16:1318-25. 2005..Transient nerve effects occur prior to permanent damage, providing an opportunity to discontinue energy delivery before permanent injury...
Sex differences in outcome after ventricular fibrillation in out-of-hospital cardiac arrestSrijoy Mahapatra
Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic College of Medicine, 200 First Street, SW, Rochester, MN 55902, USA
Resuscitation 65:197-202. 2005..CONCLUSION: Women are more likely to survive to hospital admission following an OHCA. However, admitted women less likely to survive their hospital stay. Long-term survival and QOL are equally favorable in both sexes...
Substrate and procedural predictors of outcomes after catheter ablation for atrial fibrillation in patients with hypertrophic cardiomyopathyT Jared Bunch
Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA
J Cardiovasc Electrophysiol 19:1009-14. 2008..Although catheter ablation for drug-refractory AF is an effective treatment, the efficacy in HCM remains to be established...
Mechanism of tissue heating during high intensity focused ultrasound pulmonary vein isolation: implications for atrial fibrillation ablation efficacy and phrenic nerve protectionYasuo Okumura
Translational Cardiac Electrophysiology Laboratory, Division of Cardiovascular Disease, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota 55902, USA
J Cardiovasc Electrophysiol 19:945-51. 2008..The thermodynamics and extent of PV and phrenic nerve (PN) heating during HIFU ablation have not been established...
Mechanisms and utility of discrete great arterial potentials in the ablation of outflow tract ventricular arrhythmiasKomandoor S Srivathsan
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Scottsdale, Ariz, USA
Circ Arrhythm Electrophysiol 1:30-8. 2008..The mechanisms of these discrete potentials in the great arteries and the utility of such potentials in guiding radiofrequency ablation are unknown...
Prediction of short- and long-term outcomes by electrocardiography in survivors of out-of-hospital cardiac arrestT Jared Bunch
Division of Cardiology, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA
Resuscitation 63:137-43. 2004....
Outcomes after cardiac perforation during radiofrequency ablation of the atriumT Jared Bunch
Division of Cardiovascular Disease, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA
J Cardiovasc Electrophysiol 16:1172-9. 2005..Most perforations occur in the left atrium; however, few require surgical closure. Although less than with uncomplicated procedures, the majority of patients with complete ablations achieve long-term elimination of AF...
Outcomes and in-hospital treatment of out-of-hospital cardiac arrest patients resuscitated from ventricular fibrillation by early defibrillationT Jared Bunch
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
Mayo Clin Proc 79:613-9. 2004..By the end of the 10-year study, more patients were receiving antiarrhythmic therapy, in particular ICD implantation, after hospital admission. Overall, the long-term survival in patients with VF OHCA is favorable...
Impact of age on long-term survival and quality of life following out-of-hospital cardiac arrestT Jared Bunch
Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA
Crit Care Med 32:963-7. 2004..The survival, although high, in older patients is less than that in age-matched healthy controls, and physical and emotional quality of life scores are decreased...
Mechanisms of sudden cardiac death in myocardial infarction survivors: insights from the randomized trials of implantable cardioverter-defibrillatorsT Jared Bunch
Division of Cardiovascular Diseases, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
Circulation 115:2451-7. 2007
Prognostic significance of exercise induced arrhythmias and echocardiographic variables in hypertrophic cardiomyopathyT Jared Bunch
Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA
Am J Cardiol 99:835-8. 2007..In conclusion, in this cohort of patients with HC, exercise testing was safe. Test results were associated with risk for adverse events...
Newly detected atrial fibrillation in patients with an implantable cardioverter-defibrillator is a strong risk marker of increased mortalityT Jared Bunch
Department of Internal Medicine, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA
Heart Rhythm 6:2-8. 2009..Atrial fibrillation (AF) has been associated with higher rates of all-cause mortality in patients with heart failure (HF). The risk of newly detected AF in patients receiving implantable cardioverter-defibrillator (ICD) therapy is unknown...
Efficacy and safety of circumferential pulmonary vein isolation using a novel cryothermal balloon ablation systemAlvaro V Sarabanda
Division of Cardiovascular Disease, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota 55902, USA
J Am Coll Cardiol 46:1902-12. 2005..Further studies are needed to assess the long-term efficacy and safety of this technique...
Impact of transforming growth factor-beta1 on atrioventricular node conduction modification by injected autologous fibroblasts in the canine heartT Jared Bunch
Division of Cardiovascular Disease, Department of Internal Medicine, Mayo Clinic, Rochester, MN 55902, USA
Circulation 113:2485-94. 2006..The effect on AV node conduction is substantially enhanced by pretreatment of fibroblasts with TGF-beta1. These data have therapeutic potential for the management of rapid ventricular rate during AF without pacemaker implantation...
Temporary esophageal stenting allows healing of esophageal perforations following atrial fibrillation ablation proceduresT Jared Bunch
Division of Cardiovascular Disease, Department of Internal Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
J Cardiovasc Electrophysiol 17:435-9. 2006..Prompt chest CT scans with oral and i.v. contrast should be considered in any patient with sub-sternal chest pain or dysphagia following LACA...
Distortion of right superior pulmonary vein anatomy by balloon catheters as a contributor to phrenic nerve injuryYasuo Okumura
Translational Cardiac Electrophysiology Laboratory, Division of Cardiovascular Disease, Department of Internal Medicine, Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA
J Cardiovasc Electrophysiol 20:1151-7. 2009..Initial enthusiasm for their widespread use has been dampened by phrenic nerve (PN) injury. The interaction between PN and pulmonary vein (PV) geometry contributing to PN injury is unclear...
Trends in treated ventricular fibrillation out-of-hospital cardiac arrest: a 17-year population-based studyT Jared Bunch
Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA
Heart Rhythm 1:255-9. 2004..Sudden death preventive strategies are multifactorial. These observations suggest that ICD termination of potentially lethal ventricular arrhythmias may contribute to the lower incidence of VF out-of-hospital cardiac arrest...
Incidence and predictors of cardiac perforation after permanent pacemaker placementSrijoy Mahapatra
Division of Cardiology, Mayo Clinic, Rochester, Minnesota 55902, USA
Heart Rhythm 2:907-11. 2005....
Prevalence, pathophysiology, and clinical significance of post-heart transplant atrial fibrillation and atrial flutterSaeed A L Ahmari
Department of Internal Medicine, Division of Cardiology, Mayo Clinic, Rochester, Minnesota 55905, USA
J Heart Lung Transplant 25:53-60. 2006..Similarly advanced restrictive diastolic dysfunction caused by fibrosis from repeated moderate-to-severe (grade 3 or more) rejections was predominant in the patients with arrhythmia and was a marker of poor long-term outcome...
Long-term risk of atrial fibrillation with symptomatic gastroesophageal reflux disease and esophagitisT Jared Bunch
Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA
Am J Cardiol 102:1207-11. 2008..Patients with esophagitis were more likely to develop AF, although this association requires further study...
Impact of individual and cumulative coronary risk factors on coronary flow reserve assessed by dobutamine stress echocardiographySaeed A L Ahmari
Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA
Am J Cardiol 101:1694-9. 2008..Despite a negative dobutamine stress echocardiographic result, aggressive risk factor assessment and control should be implemented in patients with coronary risk factors due to an underlying abnormal CFR...
Effect of beta-blocker therapy on mortality rates and future myocardial infarction rates in patients with coronary artery disease but no history of myocardial infarction or congestive heart failureT Jared Bunch
Mayo Clinic Foundation, Rochester, Minnesota, USA
Am J Cardiol 95:827-31. 2005..No effect was observed on longitudinal incidence of AMI or the combination of death/nonfatal MI...
Association of body weight with total mortality and with ICD shocks among survivors of ventricular fibrillation in out-of-hospital cardiac arrestT Jared Bunch
Department of Internal Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Resuscitation 77:351-5. 2008..Studies have shown an association between obesity and total mortality among people with and without coronary artery disease. This study reviews outcomes among obese survivors of ventricular fibrillation in out-of-hospital cardiac arrest...
Discrepancies between catheter tip and tissue temperature in cooled-tip ablation: relevance to guiding left atrial ablationG Keith Bruce
Division of Cardiovascular Disease, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA
Circulation 112:954-60. 2005..Neither the absence of microbubbles nor the presence of type I microbubble formation ensures against excessive tissue heating. The appearance of microbubbles may indicate possible tissue overheating and signal a need to decrease energy...
Evolution of a community-wide early defibrillation programme experience over 13 years using police/fire personnel and paramedics as respondersRoger D White
Department of Internal Medicine, Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
Resuscitation 65:279-83. 2005..Following the trial, the program was expanded as the city grew in population and area. In 1998 firefighters also were equipped with AEDs, bringing to a total 18 AEDs with police and fire personnel, in addition to paramedic capability...
A systematical analysis of in vivo contact forces on virtual catheter tip/tissue surface contact during cardiac mapping and interventionYasuo Okumura
Division of Cardiac Electrophysiology Cardiology, Department of Internal Medicine, Mayo Clinic and Foundation, Rochester, Minnesota, USA
J Cardiovasc Electrophysiol 19:632-40. 2008..While catheter tip/tissue contact has been shown to be an important determinant of ablative lesions in in vitro studies, the impact of contact on the outcomes of mapping and ablation in the intact heart has not been evaluated...
Prognostic implication of early ejection fraction on long-term mortality and quality of life following out-of-hospital cardiac arrestAkbar H Khan
Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA
Am J Cardiol 93:1027-30. 2004..However, overall long-term quality-of-life was favorable and independent of the ejection fraction...
The prognostic significance of exercise-induced atrial arrhythmiasT Jared Bunch
Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
J Am Coll Cardiol 43:1236-40. 2004..The rate of long-term cardiac death or revascularization was not influenced by the development of stress-induced atrial arrhythmias...
Novel ablative approach for atrial fibrillation to decrease risk of esophageal injuryT Jared Bunch
Division of Cardiovascular Disease, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA
Heart Rhythm 5:624-7. 2008
Outcomes after ventricular fibrillation out-of-hospital cardiac arrest: expanding the chain of survivalT Jared Bunch
Department of Internal Medicine and Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Mayo Clin Proc 80:774-82. 2005..Broadening the focus of the chain of survival to include in-hospital and long-term care will further improve favorable outcomes achieved in an early defibrillation program...
Reconstruction of occluded thoracic duct for treatment of chylopericardium: a novel surgical therapyRowlens M Melduni
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota 55905, USA
J Vasc Surg 48:1600-2. 2008..This case highlights features and management strategies of this perplexing clinical condition...
Smooth muscle cells in human coronary atherosclerosis can originate from cells administered at marrow transplantationNoel M Caplice
Division of Cardiovascular Diseases, Molecular Medicine Program, Mayo Clinic, Rochester, MN 55905, USA
Proc Natl Acad Sci U S A 100:4754-9. 2003..These data have broad implications for our understanding of the cellular components of human atherosclerotic plaque and provide a potentially novel target for future diagnostic and therapeutic strategies...
Hypokalemia during the cooling phase of therapeutic hypothermia and its impact on arrhythmogenesisSultan A Mirzoyev
Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic, Rochester, MN 55905, United States
Resuscitation 81:1632-6. 2010..This approach entails the management of physiological variables which fall outside the realm of conventional critical cardiac care. Management of serum potassium fluxes remains pivotal in the avoidance of lethal ventricular arrhythmia...
Analysis of catheter-tip (8-mm) and actual tissue temperatures achieved during radiofrequency ablation at the orifice of the pulmonary veinT Jared Bunch
Division of Cardiovascular Disease, Department of Internal Medicine, Mayo Clinic, Rochester, Minn 55902, USA
Circulation 110:2988-95. 2004..Finally, microbubbles are inconsistent markers of tissue overheating...
Early direct coronary angioplasty in survivors of out-of-hospital cardiac arrestPaul C Keelan
Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Am J Cardiol 91:1461-3, A6. 2003
Long-term outcomes of out-of-hospital cardiac arrest after successful early defibrillationT Jared Bunch
Department of Internal Medicine, Mayo Clinic, Rochester, Minn 55905, USA
N Engl J Med 348:2626-33. 2003..The quality of life among the majority of survivors is similar to that of the general population...
Fatal coronary artery disease after unrelated donor bone marrow transplantationIrene M Ghobrial
Division of Hematology and Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
Mayo Clin Proc 79:403-6. 2004..Coronary artery disease is an important, albeit rare, complication of BMT. Donor hematopoietic cells may contribute to its pathogenesis...
Unraveling the mysteries of catheter ablation for atrial fibrillation: from clinical observations to mechanistic explorationsT Jared Bunch
J Cardiovasc Electrophysiol 18:266-8. 2007
Effects of statins on six-month survival and clinical restenosis frequency after coronary stent deploymentT Jared Bunch
Cardiovascular Department, LDS Hospital and University of Utah, Salt Lake City 84143, USA
Am J Cardiol 90:299-302. 2002
Early effects of statins in patients with coronary artery disease and high C-reactive proteinJoseph B Muhlestein
Cardiovascular Department, LDS Hospital, Salt Lake City, Utah 84143, USA
Am J Cardiol 94:1107-12. 2004..This provides further evidence of an anti-inflammatory effect of statins...
Less affluent area of residence and lesser-insured status predict an increased risk of death or myocardial infarction after angiographic diagnosis of coronary diseaseBenjamin D Horne
Cardiovascular Department, LDS Hospital, Salt Lake City, Utah 84143, USA
Ann Epidemiol 14:143-50. 2004..This suggests that SES remains a significant predictor of health outcomes after CAD has developed, and that geographic measures of SES deserve further evaluation...
Early postoperative use of unfractionated heparin or enoxaparin is associated with increased surgical re-exploration for bleedingHeath U Jones
Cardiovascular Department, LDS Hospital, Salt Lake City, Utah, USA
Ann Thorac Surg 80:518-22. 2005..This delay was especially common with ENOX suggesting the need for prospective studies...
Beta-blockers reduce the incidence of clinical restenosis: prospective study of 4840 patients undergoing percutaneous coronary revascularizationJeffrey D Jackson
Division of Cardiology, Department of Medicine, LDS Hospital, Salt Lake City, Utah 84143, USA
Am Heart J 145:875-81. 2003..The mechanism by which beta-blockers conferred a protective effect against restenosis remains to be determined...
Improved long-term survival associated with stent deployment during percutaneous coronary interventions: results from a registry of 3399 patientsJoseph B Muhlestein
Division of Cardiology, Department of Cardiovascular Medicine, LDS Hospital, Salt Lake City, Utah 84143, USA
Am Heart J 150:182-7. 2005..However, few studies have had a sufficient sample size or adequate follow-up to determine whether this advantage results in a positive effect on mortality...
Decision making with biomarkers after cardiac arrest: are we there yet?T Jared Bunch
Crit Care Med 35:1411-2. 2007
A simplified approach to the challenging problem of resuscitation of patients who present in pulseless electrical activityT Jared Bunch
Crit Care Med 36:619-20. 2008
