LISA ALLYN BOARDMAN

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. ncbi Cancer and Lhermitte-Duclos disease are common in Cowden syndrome patients
    Douglas L Riegert-Johnson
    Mayo Clinic, Jacksonville, Florida, USA
    Hered Cancer Clin Pract 8:6. 2010
  2. ncbi Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states
    Aaron L Sarver
    Biostatistics and Informatics, Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA
    BMC Cancer 9:401. 2009
  3. ncbi Overexpression of MACC1 leads to downstream activation of HGF/MET and potentiates metastasis and recurrence of colorectal cancer
    Lisa A Boardman
    Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, 200 First Street SW, Gonda 9 South, Rochester, MN 55905, USA
    Genome Med 1:36. 2009
  4. ncbi Association of Peutz-Jeghers-like mucocutaneous pigmentation with breast and gynecologic carcinomas in women
    L A Boardman
    Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Medicine (Baltimore) 79:293-8. 2000
  5. ncbi Higher frequency of diploidy in young-onset microsatellite-stable colorectal cancer
    Lisa A Boardman
    Department of Gastroenterology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Clin Cancer Res 13:2323-8. 2007
  6. ncbi A search for germline APC mutations in early onset colorectal cancer or familial colorectal cancer with normal DNA mismatch repair
    L A Boardman
    Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Genes Chromosomes Cancer 30:181-6. 2001
  7. ncbi Heritable colorectal cancer syndromes: recognition and preventive management
    Lisa A Boardman
    Department of Internal Medicine, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, USA
    Gastroenterol Clin North Am 31:1107-31. 2002
  8. ncbi MYH mutations in patients with attenuated and classic polyposis and with young-onset colorectal cancer without polyps
    Liang Wang
    Department of Laboratory Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Gastroenterology 127:9-16. 2004
  9. ncbi Young-onset colorectal cancer in patients with no known genetic predisposition: can we increase early recognition and improve outcome?
    Eric J Dozois
    Division of Colon and Rectal Surgery, Mayo Clinic, Rochester, Minnesota 55905, USA
    Medicine (Baltimore) 87:259-63. 2008
  10. ncbi Polymorphisms in DNA repair genes, smoking, and pancreatic adenocarcinoma risk
    Robert R McWilliams
    Division of Medical Oncology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA
    Cancer Res 68:4928-35. 2008

Research Grants

  1. Molecular Basis of Young Onset Colorectal Cancer
    Lisa Boardman; Fiscal Year: 2006
  2. Telomere length, telomere maintenance genes and cancer risk
    Lisa Boardman; Fiscal Year: 2009
  3. Telomere length, telomere maintenance genes and cancer risk
    LISA ALLYN BOARDMAN; Fiscal Year: 2010

Collaborators

Detail Information

Publications23

  1. ncbi Cancer and Lhermitte-Duclos disease are common in Cowden syndrome patients
    Douglas L Riegert-Johnson
    Mayo Clinic, Jacksonville, Florida, USA
    Hered Cancer Clin Pract 8:6. 2010
    ..Risk estimates are vital to the development of diagnostic criteria, genetic counseling, and cancer surveillance. To further elaborate and estimate the risks associated with CS, a large cohort of patients was evaluated...
  2. ncbi Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states
    Aaron L Sarver
    Biostatistics and Informatics, Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA
    BMC Cancer 9:401. 2009
    ..Differential miRNA expression in cancer versus normal tissue is a common event and may be pivotal for tumor onset and progression...
  3. ncbi Overexpression of MACC1 leads to downstream activation of HGF/MET and potentiates metastasis and recurrence of colorectal cancer
    Lisa A Boardman
    Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, 200 First Street SW, Gonda 9 South, Rochester, MN 55905, USA
    Genome Med 1:36. 2009
    ..MACC1 may also be an important therapeutic target for CRC treatment...
  4. ncbi Association of Peutz-Jeghers-like mucocutaneous pigmentation with breast and gynecologic carcinomas in women
    L A Boardman
    Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Medicine (Baltimore) 79:293-8. 2000
    ..In particular, the relative risk for cancer in females with IMMP was significantly increased, as is true in females with PJS. However, LKB1 mutations did not contribute to the development of IMMP in the patients tested...
  5. ncbi Higher frequency of diploidy in young-onset microsatellite-stable colorectal cancer
    Lisa A Boardman
    Department of Gastroenterology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Clin Cancer Res 13:2323-8. 2007
    ..The clinicopathologic features of MSS CIN- CRC are not well delineated. We assessed the relationship between age and chromosomal instability (CIN) status as measured by ploidy and allelic imbalance in a series of MSS tumors...
  6. ncbi A search for germline APC mutations in early onset colorectal cancer or familial colorectal cancer with normal DNA mismatch repair
    L A Boardman
    Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Genes Chromosomes Cancer 30:181-6. 2001
    ..All appeared to be polymorphisms present in similar proportions in an average-risk population. We conclude that germline APC mutations do not account for familial MSS (stable microsatellite) CRC associated with few synchronous polyps...
  7. ncbi Heritable colorectal cancer syndromes: recognition and preventive management
    Lisa A Boardman
    Department of Internal Medicine, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, USA
    Gastroenterol Clin North Am 31:1107-31. 2002
    ....
  8. ncbi MYH mutations in patients with attenuated and classic polyposis and with young-onset colorectal cancer without polyps
    Liang Wang
    Department of Laboratory Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Gastroenterology 127:9-16. 2004
    ....
  9. ncbi Young-onset colorectal cancer in patients with no known genetic predisposition: can we increase early recognition and improve outcome?
    Eric J Dozois
    Division of Colon and Rectal Surgery, Mayo Clinic, Rochester, Minnesota 55905, USA
    Medicine (Baltimore) 87:259-63. 2008
    ..Our findings should promote increased awareness and the aggressive pursuit of symptoms in otherwise young, low-risk patients, as these symptoms may represent an underlying colorectal malignancy...
  10. ncbi Polymorphisms in DNA repair genes, smoking, and pancreatic adenocarcinoma risk
    Robert R McWilliams
    Division of Medical Oncology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA
    Cancer Res 68:4928-35. 2008
    ..78; 95% CI, 1.28-6.04) or D711D (OR, 2.19; 95% CI, 1.01-4.73). No other significant differences in risk were identified. Minor alleles in DNA repair genes XPF/ERCC4 and XPD/ERCC2 were associated with altered risk for pancreatic cancer...
  11. ncbi Medical errors related to inappropriate genetic testing in liver transplant patients
    Douglas L Riegert-Johnson
    Division of Gastroenterology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Genet Test 11:451-3. 2007
    ..We recommend laboratories performing genetic testing create systems to prevent inappropriate and duplicate genetic testing and that physicians be cognizant of the appropriate indications for genetic testing in liver transplant patients...
  12. ncbi The value of MUTYH testing in patients with early onset microsatellite stable colorectal cancer referred for hereditary nonpolyposis colon cancer syndrome testing
    Douglas L Riegert-Johnson
    Department of Gastroenterology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Genet Test 11:361-5. 2007
    ..Thus, MUTYH mutation testing may be a reasonable cascade test in early onset CRC found to have proficient DNA mismatch repair, regardless of pattern of family history or number of polyps...
  13. ncbi The incidence of duplicate genetic testing
    Douglas L Riegert-Johnson
    Mayo Clinic College of Medicine, Division of Gastroenterology, Rochester, Minnesota 55905, USA
    Genet Med 10:114-6. 2008
    ..A secondary objective was to determine the savings in charges that resulted from a system in place to limit HFE DGT...
  14. ncbi Frequency of defective DNA mismatch repair in colorectal cancer among the Alaska Native people
    Lisa A Boardman
    Division of Gastroenterology, Mayo Clinic College of Medicine, Minnesota 55905, USA
    Cancer Epidemiol Biomarkers Prev 16:2344-50. 2007
    ....
  15. ncbi Colorectal cancer risks in relatives of young-onset cases: is risk the same across all first-degree relatives?
    Lisa A Boardman
    Division of Gastroenterology, Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
    Clin Gastroenterol Hepatol 5:1195-8. 2007
    ..However, for young-onset microsatellite stable (MSS) CRC, the familial risk for CRC is unknown...
  16. ncbi Mitochondrial genetic polymorphisms and pancreatic cancer risk
    Liang Wang
    Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, 200 First Street Southwest, Stabile 241, Rochester, MN 55905, USA
    Cancer Epidemiol Biomarkers Prev 16:1455-9. 2007
    ..Investigation of other mitochondrial genetic variations (i.e., nuclear-encoded mitochondrial proteins) would be necessary to elucidate any role of mitochondrial DNA variation in PC...
  17. ncbi BRAF mutations in colon cancer are not likely attributable to defective DNA mismatch repair
    Liang Wang
    Department of Laboratory Medicine, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
    Cancer Res 63:5209-12. 2003
    ..Furthermore, BRAF mutations were strongly associated with the epigenetic alteration of hMLH1. Overall, these data suggest that BRAF mutations are not a consequence of defective mismatch repair per se...
  18. ncbi Relative frequency and morphology of cancers in STK11 mutation carriers
    Wendy Lim
    Section of Cancer Genetics, Institute of Cancer Research, Sutton, Surrey SM2 5NG, UK
    Gastroenterology 126:1788-94. 2004
    ..There is limited data on the spectrum and risk for cancer associated with germline serine/threonine protein kinase 11 (STK11) mutations that cause Peutz-Jeghers syndrome (PJS)...
  19. ncbi Defective DNA mismatch repair in long-term (> or =3 years) survivors with pancreatic cancer
    John T Maple
    Department of Internal Medicine, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Pancreatology 5:220-7; discussion 227-8. 2005
    ..To determine if long-term survival in pancreatic cancer could be attributed to defective DNA MMR, we ascertained its prevalence in 35 pancreatic cancer patients who survived > or =3 years after surgery...
  20. ncbi Lower cancer incidence in Amsterdam-I criteria families without mismatch repair deficiency: familial colorectal cancer type X
    Noralane M Lindor
    Department of Medical Genetics, Mayo Clinic, Rochester, Minn, USA
    JAMA 293:1979-85. 2005
    ..Cancer incidence in AC-I families with MMR gene mutations is reported to be very high, but cancer incidence for individuals in AC-I families with no evidence of an MMR defect is unknown...
  21. ncbi Genetics of colonic polyposis
    John T Maple
    Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Clin Gastroenterol Hepatol 4:831-5. 2006
  22. ncbi Frequency and spectrum of cancers in the Peutz-Jeghers syndrome
    Nicholas Hearle
    Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom
    Clin Cancer Res 12:3209-15. 2006
    ..CONCLUSIONS: The results from our study provide quantitative information on the spectrum of cancers and risks of specific cancer types associated with Peutz-Jeghers syndrome...
  23. ncbi Cronkhite-Canada syndrome hamartomatous polyps are infiltrated with IgG4 plasma cells
    Douglas L Riegert-Johnson
    Digestion 75:96-7. 2007

Research Grants4

  1. Molecular Basis of Young Onset Colorectal Cancer
    Lisa Boardman; Fiscal Year: 2006
    ..Following achievement of these goals, I am confident that I will be ready to continue my career as a successful independent investigator committed to colerectal cancer prevention and control. ..
  2. Telomere length, telomere maintenance genes and cancer risk
    Lisa Boardman; Fiscal Year: 2009
    ....
  3. Telomere length, telomere maintenance genes and cancer risk
    LISA ALLYN BOARDMAN; Fiscal Year: 2010
    ....