Research Topics
| DAVID ROBERT BARNIDGESummaryAffiliation: Mayo Clinic Country: USA Publications
Research Grants
| Collaborators |
Detail Information
Publications
Protein expression profiling of CLL B cells using replicate off-line strong cation exchange chromatography and LC-MS/MSDavid R Barnidge
Mayo Proteomics Research Center, Mayo Clinic College of Medicine, 200 1st Street SW, Rochester, MN 55905, USA
J Chromatogr B Analyt Technol Biomed Life Sci 819:33-9. 2005..We show that despite the variance in SCX, capillary LC, and the data-dependent selection of precursor ions, an overlap of 64% between proteins identified in replicate runs was achieved for this system...
Absolute quantification of the G protein-coupled receptor rhodopsin by LC/MS/MS using proteolysis product peptides and synthetic peptide standardsDavid R Barnidge
Neuromics Incorporated, Minneapolis, Minnesota 55414, USA
Anal Chem 75:445-51. 2003..We demonstrate that quantification is simple and reliable for the integral membrane protein rhodopsin with reasonable recoveries for replicate experiments using low-micromolar solutions of rhodopsin from rod outer segments...
Quantitative protein expression analysis of CLL B cells from mutated and unmutated IgV(H) subgroups using acid-cleavable isotope-coded affinity tag reagentsDavid R Barnidge
Mayo Proteomics Research Center, Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
J Proteome Res 4:1310-7. 2005..These results demonstrate that stable isotope labeling and mass spectrometry can complement 2D gel electrophoresis and gene microarray technologies for identifying putative and perhaps unique prognostic markers in CLL...
Research Grants
- B-CLL Proteins Quantified by Mass SpectrometryDAVID BARNIDGE; Fiscal Year: 2004..As part of this proposal the candidate will take courses offered in the Mayo Graduate School on Techniques in Molecular Biology, Human Cytogenetics, and Immunology. ..
