Research Topics
| B AfessaSummaryAffiliation: Mayo Clinic Country: USA Publications
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Publications
Identifying potentially ineffective care in the sickest critically ill patients on the third ICU dayBekele Afessa
Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
Chest 126:1905-9. 2004..To determine if an increase in the third-ICU-day acute physiology score (APS) of the APACHE (acute physiology and chronic health evaluation) III prognostic system can identify potentially ineffective care...
Risk factors and outcome of pulmonary complications after autologous hematopoietic stem cell transplantBekele Afessa
Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN, USA
Chest 141:442-50. 2012..This study describes the PCs, their risk factors, and the impact on mortality in autologous recipients...
Prediction of death and prolonged mechanical ventilation in acute lung injuryOgnjen Gajic
Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA
Crit Care 11:R53. 2007..We aimed to identify risk factors for a combined end-point of death and/or prolonged ventilator dependence and developed an ALI-specific prediction model...
The incidence of relative adrenal insufficiency in patients with septic shock after the administration of etomidateZulfiqar Mohammad
Department of Cardiothoracic Anesthesiology, The Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA
Crit Care 10:R105. 2006..The objective of this study was to determine the incidence of relative adrenal insufficiency in patients with septic shock after etomidate administration compared with patients with septic shock who did not receive etomidate...
APACHE III outcome prediction in patients admitted to the intensive care unit after liver transplantation: a retrospective cohort studyMark T Keegan
Division of Critical Care, Department of Anesthesiology, Mayo Clinic, Rochester, MN, USA
BMC Surg 9:11. 2009..The area under the receiver operating characteristic curve (AUC) and the Hosmer-Lemeshow C statistic were used to assess, respectively, discrimination and calibration of APACHE III...
Critical care of the hematopoietic stem cell transplant recipientBekele Afessa
Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
Crit Care Clin 26:133-50. 2010....
Association between a silver-coated endotracheal tube and reduced mortality in patients with ventilator-associated pneumoniaBekele Afessa
Division of Pulmonary and Critical Care Medicine, Mayo Clinic, 200 1st St SW, Rochester, MN 55905 0001, USA
Chest 137:1015-21. 2010..A silver-coated endotracheal tube (ETT) reduced the incidence of ventilator-associated pneumonia (VAP) compared with an uncoated ETT in the North American Silver-Coated Endotracheal Tube (NASCENT) study...
Evaluating the performance of an institution using an intensive care unit benchmarkBekele Afessa
Department of Internal Medicine and Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
Mayo Clin Proc 80:174-80. 2005..To describe the performances of selected intensive care units (ICUs) in a single institution using the Acute Physiology and Chronic Health Evaluation (APACHE) III benchmark and to propose interventions that may improve performance...
Prognostic factors, clinical course, and hospital outcome of patients with chronic obstructive pulmonary disease admitted to an intensive care unit for acute respiratory failureBekele Afessa
Department of Internal Medicine, Division of Pulmonary and Critical Care, University of Florida Health Science Center, Jacksonville, FL, USA
Crit Care Med 30:1610-5. 2002..To describe prognostic factors, clinical course, and hospital outcome of patients with chronic obstructive pulmonary disease admitted to an intensive care unit for acute respiratory failure...
Critical care support of patients with nicotine addictionBekele Afessa
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Crit Care 14:155. 2010..Despite the abundance of active smokers, there is a paucity of data describing nicotine withdrawal, and its prevention and treatment options in the critically ill. Future studies are warranted to address these issues...
Noninfectious pneumonitis after blood and marrow transplantBekele Afessa
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Curr Opin Oncol 20:227-33. 2008..This review will summarize recent developments in noninfectious complications that manifest as pulmonary infiltrates...
Association between ICU admission during morning rounds and mortalityBekele Afessa
Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN 55905, USA
Chest 136:1489-95. 2009..No previous study has evaluated the association between admission to ICUs during round time and patient outcome. The objective of this study was to determine the association between round-time ICU admission and patient outcome...
The hospital mortality of patients admitted to the ICU on weekendsS Allen Ensminger
Division of Pulmonary and Critical Care Medicine, Mayo Clinic and Foundation, 200 First Street SW, Rochester, MN 55905, USA
Chest 126:1292-8. 2004..This study was conducted to determine whether weekend admission to the ICU increases the risk of dying in the hospital...
The influence of missing components of the Acute Physiology Score of APACHE III on the measurement of ICU performanceBekele Afessa
Division of Pulmonary and Critical Care, Department of Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Intensive Care Med 31:1537-43. 2005..To determine the impact of missing Acute Physiology Score (APS) values on risk-adjusted mortality...
Severity of illness and organ failure assessment in adult intensive care unitsBekele Afessa
Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, 200 First Street, SW, Rochester, MN 55905, USA
Crit Care Clin 23:639-58. 2007..Their roles as clinical decision support tools at the bedside await future studies because of their unknown or poor performance at the individual patient level...
Predicting mortality in intensive care unit survivors using a subjective scoring systemBekele Afessa
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Crit Care 11:109. 2007..However, if it is to be generalizable and reproducible and to perform well without bias, then a good prediction model should be based on objectively defined variables...
Introduction of a 14-hour work shift model for housestaff in the medical ICUBekele Afessa
Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, 200 First St SW, Rochester, MN 55905, USA
Chest 128:3910-5. 2005..To describe the outcomes of switching housestaff from a traditional model of "long-call" every 4 days to a 14-h work-shift model in a medical ICU (MICU) over a 5-week pilot period...
Bronchoscopy in ventilator-associated pneumonia: agreement of calibrated loop and serial dilutionBekele Afessa
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Am J Respir Crit Care Med 173:1229-32. 2006....
Intensive care unit support and Acute Physiology and Chronic Health Evaluation III performance in hematopoietic stem cell transplant recipientsBekele Afessa
Department of Medicine, Division of Pulmonary and Critical Care Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Crit Care Med 31:1715-21. 2003..The objectives of this study were to describe the clinical course of HSCT recipients admitted to the ICU and to determine the performance of APACHE III in predicting their mortality...
Pleural effusions and pneumothoraces in AIDSB Afessa
Division of Pulmonary and Critical Care Medicine and Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
Curr Opin Pulm Med 7:202-9. 2001..Kaposi sarcoma and primary effusion lymphoma are associated with human herpesvirus 8. The prognosis of patients with pleural Kaposi sarcoma and non-Hodgkin lymphoma in AIDS is poor, and the major goal of treatment is palliation...
Association of pulmonary artery catheter use with in-hospital mortalityB Afessa
Division of Pulmonary and Critical Care, Department of Medicine, University of Florida Health Science Center, Jacksonville, FL, USA
Crit Care Med 29:1145-8. 2001..To determine the association of pulmonary artery catheter (PAC) use with in-hospital mortality...
Clinical course, prognostic factors, and outcome prediction for HIV patients in the ICU. The PIP (Pulmonary complications, ICU support, and prognostic factors in hospitalized patients with HIV) studyB Afessa
Department of Internal Medicine, Division of Pulmonary and Critical Care, University of Florida Health Science Center, Jacksonville, FL, USA
Chest 118:138-45. 2000..To describe the clinical course and prognostic factors in patients with HIV admitted to the ICU...
Major complications following hematopoietic stem cell transplantationBekele Afessa
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Semin Respir Crit Care Med 27:297-309. 2006..Idiopathic pneumonia syndrome occurs at any time following transplant. Bronchoscopy is usually helpful for the diagnosis of the infectious pulmonary complications and DAH...
Bacteremia in hospitalized patients with human immunodeficiency virus: A prospective, cohort studyB Afessa
Division of Pulmonary and Critical Care, University of Florida Health Science Center, Jacksonville, Florida, USA
BMC Infect Dis 1:13. 2001....
Outcome of diffuse alveolar hemorrhage in hematopoietic stem cell transplant recipientsBekele Afessa
Department of Medicine, Divisions of Pulmonary and Critical Care Medicine and Hematology, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
Am J Respir Crit Care Med 166:1364-8. 2002..This study shows that survival rate of hematopoietic stem cell transplant recipients with diffuse alveolar hemorrhage is better than previously reported, and that early onset and autologous transplant are favorable prognostic indicators...
Diffuse alveolar hemorrhage in hematopoietic stem cell transplant recipientsBekele Afessa
Department of Medicine, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
Am J Respir Crit Care Med 166:641-5. 2002
Hospital mortality rate and length of stay in patients admitted at night to the intensive care unitIan J Morales
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Mayo Clinic and Foundation, Rochester, MN, USA
Crit Care Med 31:858-63. 2003..CONCLUSIONS: Nighttime admission to our intensive care unit is not associated with a higher mortality rate or a longer hospital or intensive care unit stay compared with daytime admission...
Mortality rate and length of stay of patients admitted to the intensive care unit in JulyJavier D Finkielman
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Mayo Medical School, Mayo Clinic and Foundation, 200 First St. SW, Rochester, MN 55905, USA
Crit Care Med 32:1161-5. 2004..CONCLUSIONS: ICU admission in July is not associated with increased hospital mortality rate or ICU length of stay...
Bacterial pneumonia in hospitalized patients with HIV infection: the Pulmonary Complications, ICU Support, and Prognostic Factors of Hospitalized Patients with HIV (PIP) StudyB Afessa
Department of Internal Medicine, Division of Pulmonary and Critical Care, University of Florida Health Science Center, Jacksonville, FL
Chest 117:1017-22. 2000..To describe the causative organisms and factors associated with bacterial pneumonia and to assess its impact on the outcome of hospitalized patients with HIV...
Systemic inflammatory response syndrome, organ failure, and outcome in critically ill obstetric patients treated in an ICUB Afessa
Department of Internal Medicine, University of Florida Health Science Center, Jacksonville, FL, USA
Chest 120:1271-7. 2001..Despite the severity of illness and the development of SIRS and organ failure in most patients, the mortality rate was low...
Clinical course and outcome of patients admitted to an ICU for status asthmaticusB Afessa
Division of Pulmonary and Critical Care, University of Florida Health Science Center, Jacksonville, FL, USA
Chest 120:1616-21. 2001..Higher APACHE II score and PaCO(2) and lower arterial pH within 24 h of hospital admission are associated with increased mortality. Sepsis and nonpulmonary organ failure are more likely to develop in nonsurvivors than survivors...
The association between nighttime transfer from the intensive care unit and patient outcomeTarik Hanane
Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN, USA
Crit Care Med 36:2232-7. 2008..To determine the impact of nighttime transfer of patients from the intensive care unit (ICU) on clinical outcome...
Internal medicine resident education in the medical intensive care unit: the impact on education and patient care of a scheduling change for didactic sessionsKaiser G Lim
Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Crit Care Med 33:1534-7. 2005..CONCLUSION: Early morning didactic sessions improve the educational experience of internal medicine residents rotating in the MICU without compromising patient care...
Intraoperative ventilator settings and acute lung injury after elective surgery: a nested case control studyE R Fernandez-Perez
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Jewish Health, 1400 Jackson Street, G10a, Denver, CO 80206, USA
Thorax 64:121-7. 2009..While acute lung injury (ALI) is among the most serious postoperative pulmonary complications, its incidence, risk factors and outcome have not been prospectively studied...
Significance of elevated cardiac troponin T levels in critically ill patients with acute respiratory diseaseVlad C Vasile
Department of Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA
Am J Med 123:1049-58. 2010..After adjusting for the severity of disease measured by the Acute Physiology, Age, and Chronic Health Evaluation (APACHE) III prognostic system, we evaluated short-term (30 days) and long-term (3 years) mortality...
Fresh-frozen plasma and platelet transfusions are associated with development of acute lung injury in critically ill medical patientsHasrat Khan
Department of Internal Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Chest 131:1308-14. 2007..Transfusion has long been identified as a risk factor for acute lung injury (ALI)/ARDS. No study has formally evaluated the transfusion of specific blood products as a risk factor for ALI/ARDS in critically ill medical patients...
Outcome of patients with end-stage renal disease admitted to the intensive care unitSaqib I Dara
Division of Pulmonary and Critical Care Medicine and Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
Mayo Clin Proc 79:1385-90. 2004..There is no statistically significant difference in the performance of APACHE III and SOFA prognostic models in discriminating between 30-day survivors and nonsurvivors...
Ethical dilemmas in a randomized trial of asthma treatment: can Bayesian statistical analysis explain the results?M T Holley
Department of Emergency Medicine, University of Florida Health Science Center, Jacksonville, FL, USA
Acad Emerg Med 8:1128-35. 2001....
Characteristics associated with analgesia ordering in the intensive care unit and relationships with outcomeAmado X Freire
Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Tennessee Health Sciences Center, Memphis 38163, USA
Crit Care Med 30:2468-72. 2002..To describe clinical characteristics associated with analgesia utilization in the intensive care unit...
Outcome of patients with idiopathic pulmonary fibrosis admitted to the intensive care unitGhulam Saydain
Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
Am J Respir Crit Care Med 166:839-42. 2002..Patients with IPF and their families should be informed about the overall outlook when they make decisions about life support and ICU care...
Suspected ventilator-associated pneumonia in cardiac patients admitted to the coronary care unitS Allen Ensminger
Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, Minn. 55905, USA
Mayo Clin Proc 81:32-5. 2006..The development of VAP in CCU patients is associated with a prolonged CCU stay but not with an increased hospital mortality...
Toward the prevention of acute lung injury: protocol-guided limitation of large tidal volume ventilation and inappropriate transfusionMurat Yilmaz
Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Crit Care Med 35:1660-6; quiz 1667. 2007..We evaluated the effect of two quality improvement interventions (low tidal volume ventilation and restrictive transfusion) on the development of acute lung injury in mechanically ventilated patients...
The association of nicotine replacement therapy with mortality in a medical intensive care unitAmy H Lee
Division of Pulmonary and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA
Crit Care Med 35:1517-21. 2007..However, the safety of nicotine replacement in the critically ill has not been studied. The objective of this study was to determine the impact of nicotine replacement on the outcome of critically ill patients...
Progression of organ failure in patients approaching brain stem deathF T Lytle
Division of Critical Care, Department of Anesthesiology, Mayo Clinic College of Medicine Rochester, MN, USA
Am J Transplant 9:1446-50. 2009..8 h (9.5-17.6). The fact that mean SOFA scores did not change significantly over time, even after BSD occurred, has implications for the timing of retrieval of organs for transplantation...
Low baseline serum creatinine concentration predicts mortality in critically ill patients independent of body mass indexRodrigo Cartin-Ceba
Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Mayo Epidemiology and Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
Crit Care Med 35:2420-3. 2007..We hypothesized that low baseline serum creatinine would predict poor outcome in the critically ill...
Transfusion-related acute lung injury in the critically ill: prospective nested case-control studyOgnjen Gajic
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Am J Respir Crit Care Med 176:886-91. 2007..Several transfusion characteristics have been postulated as risk factors for TRALI, but the evidence is limited to retrospective studies...
Effect of 24-hour mandatory versus on-demand critical care specialist presence on quality of care and family and provider satisfaction in the intensive care unit of a teaching hospitalOgnjen Gajic
Mayo Clinic College of Medicine, Rochester, MN, USA
Crit Care Med 36:36-44. 2008..We compared the quality of care and patient/family and provider satisfaction before and after changing the staffing model from on-demand to continuous 24-hr critical care specialist presence in the intensive care unit...
The acute physiology and chronic health evaluation III outcome prediction in patients admitted to the intensive care unit after pneumonectomyMark T Keegan
Department of Anesthesia, Division of Critical Care, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
J Cardiothorac Vasc Anesth 21:832-7. 2007..The purpose of this study was to determine if the APACHE III predicts hospital mortality after pneumonectomy...
Elevated cardiac troponin is an independent risk factor for short- and long-term mortality in medical intensive care unit patientsLuciano Babuin
Division of Cardiovascular Diseases, Department of Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA
Crit Care Med 36:759-65. 2008..Troponin elevations are common in critically ill patients. Whether they are predictors of mortality independent of the severity of the underlying disease is unclear...
Hospitalized patients with 2009 H1N1 influenza infection: the Mayo Clinic experienceChakradhar Venkata
Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN 55905, USA
Mayo Clin Proc 85:798-805. 2010..To describe the clinical course and outcome of adults hospitalized with the 2009 H1N1 influenza infection...
Outcome of critically ill patients with influenza virus infectionGuangxi Li
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic, Rochester, MN 55905, United States
J Clin Virol 46:275-8. 2009..An accurate prognosis is essential for decision-making during pandemic as well as interpandemic periods...
Physician staffing models and patient safety in the ICUOgnjen Gajic
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Chest 135:1038-44. 2009..In this commentary, we will discuss the available evidence behind the current models and express our opinions about current and future ICU intensivist staffing...
Acute Physiology and Chronic Health Evaluation (APACHE) III outcome prediction after major vascular surgeryMark T Keegan
Department of Anesthesiology, Division of Critical Care, Mayo Clinic, Rochester, MN 55905, USA
J Cardiothorac Vasc Anesth 22:713-8. 2008..To investigate the performance of the Acute Physiology and Chronic Health Evaluation (APACHE) III scoring system in patients admitted to the intensive care unit (ICU) after major vascular surgery...
Comparison of community and referral intensive care unit patients in a tertiary medical center: evidence for referral bias in the critically illEdward G Seferian
Division of Pediatric Critical Care Medicine, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA
Crit Care Med 36:2779-86. 2008....
Changes in intensive care unit performance measures associated with opening a dedicated thoracic surgical progressive care unitMark T Keegan
Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905, USA
J Cardiothorac Vasc Anesth 22:347-53. 2008..To determine the effect of the introduction of a specialty-specific progressive care unit (PCU) on the intensive care unit (ICU) to which relatively low-acuity patients had previously been admitted...
The Stability and Workload Index for Transfer score predicts unplanned intensive care unit patient readmission: initial development and validationOgnjen Gajic
Department of Internal Medicine and the Mayo Epidemiology and Translational Research in Intensive Care Program, Mayo Clinic College of Medicine, Rochester, MN, USA
Crit Care Med 36:676-82. 2008..The objective of this study is to develop and validate a numerical index, named the Stability and Workload Index for Transfer, to predict ICU readmission...
Peripheral blood stem cell transplant for POEMS syndrome is associated with high rates of engraftment syndromeAngela Dispenzieri
Division of Hematology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Eur J Haematol 80:397-406. 2008..Unraveling the mechanisms of the syndrome both in the context of ASCT and in general are challenges for the future...
Early identification of patients at risk of acute lung injury: evaluation of lung injury prediction score in a multicenter cohort studyOgnjen Gajic
Mayo Clinic, Rochester, MN 55905, USA
Am J Respir Crit Care Med 183:462-70. 2011..Objectives: To determine the frequency and outcome of ALI development in patients at risk and validate a lung injury prediction score (LIPS)...
Transfusion from male-only versus female donors in critically ill recipients of high plasma volume componentsOgnjen Gajic
Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA
Crit Care Med 35:1645-8. 2007..The objective of this study was to evaluate the effect of transfusing components from male-only vs. female donors on development of ALI, gas exchange, and outcome in critically ill patients...
The clinical utility of flexible bronchoscopy in the evaluation of chronic coughTerrance W Barnes
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA
Chest 126:268-72. 2004..To assess the clinical utility of flexible bronchoscopy (FB) in the evaluation of patients with chronic cough and normal or nonlocalizing chest radiographic findings...
Acute lung injury after hematopoietic stem cell transplantationSteve G Peters
Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Clin Chest Med 26:561-9, vi. 2005..A major proportion of these complications are the direct result of infection. This article addresses early, noninfectious causes of acute lung injury in the HSCT recipient...
Infectious complications in survivors of cardiac arrest admitted to the medical intensive care unitOgnjen Gajic
Division of Pulmonary and Critical Care Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Resuscitation 60:65-9. 2004..To describe the incidence, associated factors and outcome of infectious complications in patients admitted to the medical intensive care unit (MICU) after cardiopulmonary resuscitation (CPR)...
Increased risk associated with pulmonary artery catheterization in the medical intensive care unitSteve G Peters
Department of Medicine, Division of Pulmonary and Critical Care Medicine, Mayo Clinic and Foundation, Rochester, MN 55905, USA
J Crit Care 18:166-71. 2003....
Demographic and clinical variation of adult intensive care unit utilization from a geographically defined populationEdward G Seferian
Division of Pediatric Critical Care Medicine, Department of Pediatric and Adolescent Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Crit Care Med 34:2113-9. 2006..To determine population-based rates of adult intensive care unit (ICU) use and evaluate the effects that demographic variables and chronic illness have on ICU utilization...
Prophylactic endotracheal intubation in critically ill patients undergoing endoscopy for upper GI hemorrhageAhmer Rehman
Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
Gastrointest Endosc 69:e55-9. 2009..Cardiopulmonary complications are common after endoscopy for upper GI (UGI) hemorrhage in the intensive care unit (ICU)...
Adult intensive care unit use at the end of life: a population-based studyEdward G Seferian
Division of Pediatric Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
Mayo Clin Proc 81:896-901. 2006..To determine population-based rates of intensive care unit (ICU) use at the end of life in adults and describe demographic and clinical variation in end-of-life ICU use...
Outcome of patients with small-vessel vasculitis admitted to a medical ICUS Anjum Khan
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA
Chest 131:972-6. 2007..This study aims to describe the clinical course and prognostic factors of patients with small-vessel vasculitis admitted to a medical ICU...
Ventilator-associated lung injury in patients without acute lung injury at the onset of mechanical ventilationOgnjen Gajic
Division of Pulmonary and Critical Care Medicine, Mayo Clinic Rochester, MN, USA
Crit Care Med 32:1817-24. 2004..Strong consideration should be given to limiting large tidal volume, not only in patients with established acute lung injury but also in patients at risk for acute lung injury...
Is there a role for inhaled nitric oxide as a rescue therapy in respiratory failure associated with hematologic malignancies?Mark T Keegan
Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Am J Hematol 81:729-34. 2006..Therefore, despite initial improvement in oxygenation, we did not observe any survival benefit to INO in this setting...
Chronic lung disease after hematopoietic stem cell transplantationBekele Afessa
Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Clin Chest Med 26:571-86, vi. 2005..This article reviews some of the noninfectious, chronic pulmonary complications...
Fresh frozen plasma transfusion in critically ill medical patients with coagulopathySaqib I Dara
Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN, USA
Crit Care Med 33:2667-71. 2005..CONCLUSION: The risk-benefit ratio of FFP transfusion in critically ill medical patients with coagulopathy may not be favorable. Randomized controlled trials evaluating restrictive vs. liberal FFP transfusion strategies are warranted...
Predictors of intensive care unit and hospital length of stay in diabetic ketoacidosisAmado X Freire
Department of Medicine, The University of Tennessee Health Sciences Center, Memphis, TN 38163, USA
J Crit Care 17:207-11. 2002....
Intensivist-to-bed ratio: association with outcomes in the medical ICUSaqib I Dara
Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Chest 128:567-72. 2005..CONCLUSION: Differences in intensivist-to-ICU bed ratios, ranging from 1:7.5 to 1:15, were not associated with differences in ICU or hospital mortality. However, a ratio of 1:15 was associated with increased ICU LOS...
Bronchiolitis obliterans and other late onset non-infectious pulmonary complications in hematopoietic stem cell transplantationB Afessa
Division of Pulmonary and Critical Care, Department of Internal Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Bone Marrow Transplant 28:425-34. 2001..BO and BOOP occur almost exclusively in allogeneic HSCT, and have 61% and 21% mortality rates, respectively. BOOP responds favorably to corticosteroids. IPS has less than 15% 1-year survival...
Predicting 3-day and 7-day outcomes of weaning from mechanical ventilationB Afessa
Department of Medicine, University of Florida Health Science Center, Jacksonville, USA
Chest 116:456-61. 1999..To determine the correlation of acute physiology and chronic health evaluation (APACHE) II score and various weaning indexes (WIs) with 3- and 7-day weaning outcomes...
Candida bloodstream infections in intensive care units: analysis of the extended prevalence of infection in intensive care unit studyDaniel H Kett
Department of Medicine, Division of Pulmonary and Critical Care, The University of Miami Miller School of Medicine and Jackson Memorial Hospital, Miami, FL, USA
Crit Care Med 39:665-70. 2011..To provide a global, up-to-date picture of the prevalence, treatment, and outcomes of Candida bloodstream infections in intensive care unit patients and compare Candida with bacterial bloodstream infection...
Paroxysmal atrial fibrillation in critically ill patients with sepsisSalam Salman
Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
J Intensive Care Med 23:178-83. 2008..It occurs more frequently in patients with advanced age, history of paroxysmal atrial fibrillation, high severity of illness, and lower left ventricular ejection fraction and is associated with increased mortality...
Long-term prognostic significance of elevated cardiac troponin levels in critically ill patients with acute gastrointestinal bleedingVlad C Vasile
Division of Cardiovascular Diseases, Department of Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA
Crit Care Med 37:140-7. 2009..However, there are no data addressing the independent association of troponin levels and mortality, adjusted for the severity of the underlying disease, in patients with GI bleeding...
The clinical course of patients with septic abortion admitted to an intensive care unitJavier Daniel Finkielman
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Mayo Clinic and Foundation, 200 First Street SW, Rochester, MN 55905, USA
Intensive Care Med 30:1097-102. 2004..0001), and pulmonary artery catheter (8 vs 41%, p=0.0026). CONCLUSIONS: Although it is an avoidable complication, septic abortion requiring admission to the ICU is associated with high morbidity and mortality...
From "pro and con" debate to evidence-based practice: ventilator-associated pneumoniaBekele Afessa
Chest 125:1600-2. 2004
Pulmonary complications in adult blood and marrow transplant recipients: autopsy findingsSunita Sharma
Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Chest 128:1385-92. 2005..As the result of underdiagnosis, BMT recipients may not receive appropriate therapy for potentially treatable pulmonary complications...
Silver-coated endotracheal tubes and incidence of ventilator-associated pneumonia: the NASCENT randomized trialMarin H Kollef
Washington University School of Medicine, 660 S Euclid Ave, St Louis, MO 63110, USA
JAMA 300:805-13. 2008..Ventilator-associated pneumonia (VAP) causes substantial morbidity. A silver-coated endotracheal tube has been designed to reduce VAP incidence by preventing bacterial colonization and biofilm formation...
The intensive care support of patients with malignancy: do everything that can be doneElie Azoulay
Intensive Care Med 32:3-5. 2006
Intensive care unit physician staffing: seven days a week, 24 hours a dayBekele Afessa
Crit Care Med 34:894-5. 2006
Evidence-based red cell transfusion in the critically ill: quality improvement using computerized physician order entryRimki Rana
Family Medicine Residency, Mercy Medical Center-North Iowa, Mason City, IA, USA
Crit Care Med 34:1892-7. 2006..12; 95% confidence interval, 0.69 to 1.8). CONCLUSIONS: The implementation of an institutional protocol and decision support through a computerized provider order entry effectively decreased inappropriate red cell transfusions...
Benchmark for intensive care unit length of stay: One step forward, several more to goBekele Afessa
Crit Care Med 34:2674-6. 2006
Pretransplant pulmonary evaluation of the blood and marrow transplant recipientBekele Afessa
Chest 128:8-10. 2005
Chronic cough from the patient's perspectiveTomasz J Kuzniar
Sleep Disorders Center, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
Mayo Clin Proc 82:56-60. 2007..To identify the factors that patients consider most concerning about their cough...
The role of autopsy in the intensive care unitHassan F Nadrous
Division of Pulmonary and Critical Care Medicine and Internal Medicine, Mayo Clinic, Rochester, Minn 55905, USA
Mayo Clin Proc 78:947-50. 2003..Transplant recipients are especially likely to have occult conditions for which additional therapy might be indicated...
Risk factors for the development of acute lung injury in patients with septic shock: an observational cohort studyRemzi Iscimen
Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Mayo Clini, Rochester, Minnesota, USA
Crit Care Med 36:1518-22. 2008..The understanding why some patients do and others do not develop ALI is limited. The objective of this study was to test the hypothesis that delayed treatment of septic shock is associated with the development of ALI...
