Research Topics
| A ZembowiczSummaryAffiliation: Massachusetts General Hospital Country: USA Publications
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Detail Information
Publications
Dermal dendritic melanocytic proliferations: an updateA Zembowicz
Dermatopathology Unit, Department of Pathology, Massachusetts General Hospital and Massachusetts Eye and Ear Infirmary, Harvard Medical School, Harvard, MA 02114, USA
Histopathology 45:433-51. 2004..The purpose of this review is to provide an update on recent developments in the field with emphasis on new entities and their differential diagnosis...- Amelanotic cellular blue nevus: a hypopigmented variant of the cellular blue nevus: clinicopathologic analysis of 20 casesArtur Zembowicz
Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA
Am J Surg Pathol 26:1493-500. 2002..In particular, amelanotic cellular blue nevus must be distinguished from malignant cellular blue nevus and other variants of melanoma... - Endocrine mucin-producing sweat gland carcinoma: twelve new cases suggest that it is a precursor of some invasive mucinous carcinomasArtur Zembowicz
Dermatopathology Unit, Department of Pathology, Warren 820, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
Am J Surg Pathol 29:1330-9. 2005..Although the data from this series support the notion that the prognosis of EMPSGC and mucinous carcinoma is good, longer follow-up is needed for better understanding of their pathogenesis and clinical behavior... - Histological spectrum of cutaneous reactions to aspirin in chronic idiopathic urticariaArtur Zembowicz
Department of Pathology, Harvard Medical School and Massachusetts General Hospital, Warren 820, 55 Fruit Street, Boston, MA 02114, USA
J Cutan Pathol 31:323-9. 2004..This presented the rare opportunity to evaluate histological features of a series of skin eruptions induced by a drug acting through a defined mechanism in a controlled experimental setting... - Pigmented epithelioid melanocytoma: a low-grade melanocytic tumor with metastatic potential indistinguishable from animal-type melanoma and epithelioid blue nevusArtur Zembowicz
Dermatopathology Unit, Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
Am J Surg Pathol 28:31-40. 2004..We suggest that PEM be considered as a provisional histologic entity encompassing both animal-type melanoma and epithelioid blue nevus... - Safety of cyclooxygenase 2 inhibitors and increased leukotriene synthesis in chronic idiopathic urticaria with sensitivity to nonsteroidal anti-inflammatory drugsArtur Zembowicz
Department of Pathology, Harvard Medical School and Massachusetts General Hospital, Boston, USA
Arch Dermatol 139:1577-82. 2003..Sensitivity to NSAIDs in CIU is associated with overproduction of cysteinyl leukotrienes and mast cell activation and most likely depends on inhibition of cyclooxygenase 1... - Non-bullous neutrophilic dermatosis: an uncommon dermatologic manifestation in patients with lupus erythematosusBriana C Gleason
Department of Pathology, Brigham and Women s Hospital, Boston, MA 02115, USA
J Cutan Pathol 33:721-5. 2006..Rare cases of a non-bullous neutrophilic dermatosis occurring in patients with lupus erythematosus (LE) have been reported, often as the presenting manifestation of the disease... - Loss of expression of protein kinase a regulatory subunit 1alpha in pigmented epithelioid melanocytoma but not in melanoma or other melanocytic lesionsArtur Zembowicz
Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Am J Surg Pathol 31:1764-75. 2007..Loss of expression of R1alpha offers a useful diagnostic test that helps to distinguish PEM from lesions that mimic it histologically... - CD20+ T-cell lymphoma: clinicopathologic analysis of 9 cases and a review of the literatureAliyah Rahemtullah
James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Boston, MA 02114, USA
Am J Surg Pathol 32:1593-607. 2008..Knowledge of the unusual phenomenon of CD20 expression in TCL, in conjunction with careful morphologic analysis, the use of a panel of antibodies, and molecular genetic studies, is important in avoiding a misdiagnosis of BCL... - Lues maligna in early HIV infection case report and review of the literatureJoseph D Tucker
Division of Infection Diseases, Massachusetts General Hospital, 55 Fruit St, GRJ 504, Boston, MA 02114, USA
Sex Transm Dis 36:512-4. 2009..The classic lesion of lues maligna is an oval, papulopustular skin lesion with well demarcated borders sometimes covered with a lamellar crust, but myriad clinical presentations of this disease also exist... - Treatment of synchronous mucinous carcinoma and endocrine mucin-producing sweat gland carcinoma with Mohs' micrographic surgeryZeina S Tannous
Department of Dermatology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Dermatol Surg 31:364-7. 2005..We report a case of an endocrine mucin-producing sweat gland carcinoma associated with mucinous carcinoma treated by Mohs' micrographic surgery... - Whole-slide imaging digital pathology as a platform for teleconsultation: a pilot study using paired subspecialist correlationsDavid C Wilbur
Department of Pathology, James Homer Wright Pathology Laboratories, Massachusetts General Hospital, and the Department of Pathology, Harvard Medical School, Boston, MA 02114, USA
Arch Pathol Lab Med 133:1949-53. 2009..Before implementation, technical issues, pathologist adaptability, and morphologic pitfalls must be well characterized... - Morphological analysis of nevoid melanoma: a study of 20 cases with a review of the literatureA Zembowicz
Division of Dermatopathology, Department of Pathology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA
Am J Dermatopathol 23:167-75. 2001..Our data and a review of the literature do not support the notion that nevoid melanoma has a better prognosis than ordinary melanoma... - Case records of the Massachusetts General Hospital. Case 19-2006. A 22-month-old boy with the rapid growth of subcutaneous nodulesJ Patrick Whelan
Pediatric Rheumatology Service, Massachusetts General Hospital, USA
N Engl J Med 354:2697-704. 2006 - Endocrine mucin-producing sweat gland carcinoma of the eyelidSonia Mehta
Boston University School of Medicine, Massachusetts General Hospital, Boston, MA, USA
Ophthal Plast Reconstr Surg 24:164-5. 2008..She underwent Mohs surgery and reconstruction of the resulting defect. Clinicians should be aware of this entity given its association with invasive mucinous adenocarcinoma, a locally aggressive tumor with metastatic potential... - Pigmented epithelioid melanocytoma: favorable outcome after 5-year follow-upRajni V Mandal
Department of Pathology, Massachusetts General Hospital, Boston, MA, USA
Am J Surg Pathol 33:1778-82. 2009..These findings provide further evidence that PEM is a unique low-grade melanocytic tumor with limited metastatic potential (to lymph nodes), but a favorable long-term clinical course... - Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 5-2003 - a 16-year-old girl with a rash and chest painIvor Caro
Dermatology Clinical Investigations Unit, Department of Dermatology, Massachusetts General Hospital, Boston, USA
N Engl J Med 348:630-7. 2003 - Prevalence of melanoma clinically resembling seborrheic keratosis: analysis of 9204 casesLeonid Izikson
Harvard Medical School, Boston, MA, USA
Arch Dermatol 138:1562-6. 2002..CONCLUSIONS: Our results confirm that melanoma can mimic seborrheic keratosis. These data strongly support the current policy of submitting for histological examination all specimens that have been removed from patients... - Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 7-2004. A 48-year-old woman with multiple pigmented lesions and a personal and family history of melanomaHensin Tsao
Wellman Center for Photomedicine, Massachusetts General Hospital, USA
N Engl J Med 350:924-32. 2004 - Atypical genital nevi. A clinicopathologic analysis of 56 casesBriana C Gleason
Department of Pathology, Brigham and Women s Hospital, Boston, MA, USA
Am J Surg Pathol 32:51-7. 2008..Awareness and recognition of this group of melanocytic lesions is important to avoid over diagnosis as melanoma with subsequent wide excision and possibly sentinel lymph node biopsy... - Clinical and pathologic findings of paraneoplastic dermatosesVinh Q Chung
Harvard Medical School, Boston, Massachusetts, USA
J Am Acad Dermatol 54:745-62; quiz 763-6. 2006..LEARNING OBJECTIVE: At the conclusion of this leaning activity, participants should be able to recognize, diagnose, and describe the clinical and pathologic findings of paraneoplastic dermatoses... - Warfarin-induced skin necrosisRosalynn M Nazarian
Department of Pathology and Dermatopathology Unit, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts 02114, USA
J Am Acad Dermatol 61:325-32. 2009..Herein, we review the clinical and histologic features helpful for differentiating warfarin-induced skin necrosis and report a case illustrative of the diagnostic difficulty that may at times be encountered in clinical practice... - Case records of the Massachusetts General Hospital. Case 25-2007. A 60-year-old man with fever, odynophagia, weight loss, and rashMandakolathur R Murali
Department of Medicine, Massachusetts General Hospital, USA
N Engl J Med 357:692-701. 2007 - Histological evolution of lentiginous melanoma: a report of five new casesTracy Davis
Department of Pathology, Massachusetts General Hospital and Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
J Cutan Pathol 34:296-300. 2007..We report five similar cases... - Combined basal cell carcinoma and Langerhans cell histiocytosis of the scrotum in a patient with occupational exposure to coal tar and dustLeonid Izikson
Division of Dermatopathology, Department of Pathology, Massachusetts General Hospital, Harvard Medical School, and Harvard Vanguard Medical Associates, Boston, MA 02114, USA
Int J Dermatol 43:678-80. 2004 - Low-risk and high-risk histologic features in conjunctival primary acquired melanosis with atypia: Clinicopathologic analysis of 29 casesMitsuhiro Sugiura
Department of Pathology, Massachusetts General Hospital Harvard Medical School, Boston, MA, USA
Am J Surg Pathol 31:185-92. 2007..Our findings offer a practical approach for prognostically useful subclassification of PAM with atypia, which emphasizes cytologic features of intraepithelial conjunctival melanocytic proliferation... - Case records of the Massachusetts General Hospital. Case 14-2007. A 59-year-old man with fever and pain and swelling of both eyes and the right earJoan R Butterton
Infectious Disease Division, Massachusetts General Hospital, USA
N Engl J Med 356:1980-8. 2007 - Phakomatous choristoma of the eyelid: a report of a caseKatherine Szyfelbein
Harvard Medical School, Boston, MA 02114, USA
J Cutan Pathol 31:506-8. 2004..Our case illustrates unique histological features of this entity which has to be included in differential diagnosis of skin lesions of the inferonasal eyelid... - Fine-needle aspiration biopsy of a cystic pleomorphic adenoma with extensive adnexa-like differentiation: differential diagnostic pitfall with mucoepidermoid carcinomaElena F Brachtel
Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Diagn Cytopathol 28:100-3. 2003.... - Linear ectodermal cutaneous hamartomaRebecca Campen
Department of Dermatology, Harvard Medical School, Boston, MA, USA
Int J Dermatol 42:376-9. 2003 - Case records of the Massachusetts General Hospital. Case 2-2007. A 49-year-old woman with a pigmented lesion on the armJohn F Thompson
Sydney Melanoma Unit, Sydney Cancer Centre, Royal Prince Alfred Hospital, Sydney, Australia
N Engl J Med 356:285-92. 2007 - Androgen receptor expression helps to differentiate basal cell carcinoma from benign trichoblastic tumorsLeonid Izikson
Department of Dermatology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
Am J Dermatopathol 27:91-5. 2005..These results confirm the lack of expression of androgen receptor in benign trichoblastic neoplasms and indicate that androgen receptor expression by tumor cells points to basal cell carcinoma as the most likely diagnosis... - Case records of the Massachusetts General Hospital. Case 32-2008. A 10-year-old girl with recurrent oral lesions and cutaneous bullaeJames G H Dinulos
Department of Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA
N Engl J Med 359:1718-24. 2008 - Cutaneous metastases of follicular thyroid carcinoma: a report of four cases and a review of the literatureTimothy R Quinn
Pathology Services, Inc, Cambridge, Massachusetts, USA
Am J Dermatopathol 27:306-12. 2005..Awareness of the varied morphologies of metastatic follicular thyroid carcinoma to the skin may prompt immunohistochemical analysis and the request for a complete clinical history, ultimately preventing misdiagnosis... - Adnexal clear cell carcinoma with comedonecrosis: clinicopathologic analysis of 12 casesIskander H Chaudhry
Department of Pathology, Leeds General Infirmary, Leeds, United Kingdom
Arch Pathol Lab Med 131:1655-64. 2007..Cutaneous clear cell tumors can pose a diagnostic challenge even to the experienced dermatopathologist; this is partly because of limitations of existing diagnostic categories...