Research Topics
Species | A O MareeSummaryAffiliation: Massachusetts General Hospital Country: USA Publications
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Detail Information
Publications
Cyclooxygenase-1 haplotype modulates platelet response to aspirinA O Maree
Department of Clinical Pharmacology, Royal College of Surgeons, Ireland
J Thromb Haemost 3:2340-5. 2005..Despite clear benefit from aspirin in patients with cardiovascular disease (CAD), evidence of heterogeneity in the way individuals respond has given rise to the concept of 'aspirin resistance.'..
G-protein beta3 subunit polymorphism and bleeding in the orbofiban in patients with unstable coronary syndromes-thrombolysis in myocardial infarction 16 trialA O Maree
Department of Clinical Pharmacology, Royal College of Surgeons, Dublin, Ireland
J Thromb Haemost 8:934-41. 2010..This truncated protein carried by GNB3 T allele carriers is linked to coronary artery disease and implicated as a genetic marker of drug response. Large studies of Caucasians associate T allele carriage with lower platelet reactivity...
