Research Topics
Genomes and GenesSpecies | Elizabeth A LawsonSummaryAffiliation: Massachusetts General Hospital Country: USA Publications
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Publications
Leptin levels are associated with decreased depressive symptoms in women across the weight spectrum, independent of body fatElizabeth A Lawson
Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
Clin Endocrinol (Oxf) 76:520-5. 2012..We investigated the relationship between leptin and ghrelin levels and symptoms of depression, anxiety and perceived stress in women across the weight spectrum...
Decreased nocturnal oxytocin levels in anorexia nervosa are associated with low bone mineral density and fat massElizabeth A Lawson
Neuroendocrine Unit, Bulfinch 457B, Massachusetts General Hospital, Boston, MA 02114, USA
J Clin Psychiatry 72:1546-51. 2011..Our objective was to investigate the relationship between oxytocin levels, bone mineral density, and body composition in women with anorexia nervosa...
Appetite-regulating hormones cortisol and peptide YY are associated with disordered eating psychopathology, independent of body mass indexElizabeth A Lawson
Neuroendocrine Unit, Bulfinch 457B Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Eur J Endocrinol 164:253-61. 2011..We therefore studied the relationship between orexigenic and anorexigenic hormones and disordered eating psychopathology in women across a range of weights...
Hypercortisolemia is associated with severity of bone loss and depression in hypothalamic amenorrhea and anorexia nervosaElizabeth A Lawson
Neuroendocrine Unit, Bulfinch 457B, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
J Clin Endocrinol Metab 94:4710-6. 2009..Significant hypercortisolemia, as in Cushing's disease, causes bone loss. It is unknown whether anxiety and depression and/or cortisol dysregulation contribute to low bone density in AN or HA...
Hormone predictors of abnormal bone microarchitecture in women with anorexia nervosaElizabeth A Lawson
Neuroendocrine Unit, Bulfinch 457B, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
Bone 46:458-63. 2010..We concluded that bone microarchitecture is abnormal in women with AN. Endogenous IGF-I, leptin, and androgen levels predict bone microarchitecture independent of BMI...
Effects of recombinant human growth hormone in anorexia nervosa: a randomized, placebo-controlled studyPouneh K Fazeli
Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
J Clin Endocrinol Metab 95:4889-97. 2010..The effects of supraphysiological recombinant human GH (rhGH) on GH resistance in AN are not currently known...
Peptide YY (PYY) levels and bone mineral density (BMD) in women with anorexia nervosaAndrea L Utz
Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
Bone 43:135-9. 2008..Y2 receptor knockout mice have increased bone mineral density (BMD) and thus PYY may play a role in regulating bone mass. We hypothesized that PYY levels would be inversely associated with BMD in women with AN...
Effects of risedronate and low-dose transdermal testosterone on bone mineral density in women with anorexia nervosa: a randomized, placebo-controlled studyKaren K Miller
Neuroendocrine Unit, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
J Clin Endocrinol Metab 96:2081-8. 2011..Estrogen administration has not been shown to prevent bone loss in this population, and to date, there are no approved, effective therapies for this comorbidity...
Hormonal and nutritional effects on cardiovascular risk markers in young womenElizabeth A Lawson
Neuroendocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
J Clin Endocrinol Metab 92:3089-94. 2007..Moreover, oral estrogens, known to increase hsCRP in other populations, are commonly prescribed in AN. To date, hsCRP levels and their physiological determinants have not been reported in women with AN...
Reduced amylin levels are associated with low bone mineral density in women with anorexia nervosaMonica H Wojcik
Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
Bone 46:796-800. 2010..Peptide hormones, including amylin, GIP, and GLP2, are released immediately after nutrient intake and may be involved in the regulation of bone turnover...
Androgen deficiency: association with increased anxiety and depression symptom severity in anorexia nervosaKaren K Miller
Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
J Clin Psychiatry 68:959-65. 2007..Because androgens are known to affect mood and behavior, we hypothesized that low endogenous androgen production in anorexia nervosa would predict anxiety and depression severity...
Determinants of skeletal loss and recovery in anorexia nervosaKaren K Miller
Neuroendocrine Unit, Bulfinch 457B, Massachusetts General Hospital, Boston, MA 02114, USA
J Clin Endocrinol Metab 91:2931-7. 2006..Anorexia nervosa (AN) is complicated by severe bone loss. The effects of persistent undernutrition and consequent neuroendocrine dysfunction on bone mass and the factors influencing skeletal recovery have not been well characterized...
Endocrine abnormalities in anorexia nervosaElizabeth A Lawson
Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
Nat Clin Pract Endocrinol Metab 4:407-14. 2008..Although AN is increasingly prevalent among boys and men, the disorder predominantly affects girls and women who are, therefore, the focus of this Review...
Gender effects on cardiac valvular function in hyperprolactinaemic patients receiving cabergoline: a retrospective studyLisa B Nachtigall
Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
Clin Endocrinol (Oxf) 72:53-8. 2010..Ergot-derived dopamine agonists are associated with increased risk of valvular dysfunction in Parkinson's disease. The risk of valvular disease associated with lower doses of cabergoline used to treat prolactinomas remains controversial...
Hypoglycemia from IGF2 overexpression associated with activation of fetal promoters and loss of imprinting in a metastatic hemangiopericytomaElizabeth A Lawson
Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
J Clin Endocrinol Metab 94:2226-31. 2009..The mechanism of IGF2 overexpression in non-islet-cell tumor hypoglycemia is not understood...
