Research Topics
Species | Bonnie I GlanzSummaryAffiliation: Massachusetts General Hospital Country: USA Publications
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Detail Information
Publications
Cognitive deterioration in patients with early multiple sclerosis: a 5-year studyBonnie I Glanz
Department of Neurology, Brigham and Women s Hospital, Boston, Massachusetts, USA
J Neurol Neurosurg Psychiatry 83:38-43. 2012..Methodological issues associated with longitudinal cognitive research such as practice effects and drop-outs were also examined...
Cognitive dysfunction in patients with clinically isolated syndromes or newly diagnosed multiple sclerosisB I Glanz
Department of Neurology, Brigam and Women s Hospital, Harvard Medical School, Boston, MA, USA
Mult Scler 13:1004-10. 2007..These findings suggest that cognitive impairment may predate the appearance of gross structural abnormalities on MRI and serve as an early marker of disease activity in MS...
The association between cognitive impairment and quality of life in patients with early multiple sclerosisBonnie I Glanz
Department of Neurology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
J Neurol Sci 290:75-9. 2010..Our results suggest that cognitive remediation programs aimed at improving cognitive skills may also improve quality of life for patients with early MS...
Patient reported outcomes in benign multiple sclerosisLine E Hviid
Partners Multiple Sclerosis Center, Brigham and Women s Hospital Harvard Medical Institute, Brookline, MA 02445, USA
Mult Scler 17:876-84. 2011..Benign MS patients have a mild course of disease and show no or minimal accumulation of disability over time. Little is known about the patient reported outcomes (PROs) in benign MS...
Rate of brain atrophy in benign vs early multiple sclerosisSusan A Gauthier
Department of Neurology, Partners Multiple Sclerosis Center, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Arch Neurol 66:234-7. 2009..Benign multiple sclerosis (MS) is defined by minimal or no disability after many years of observation, therefore a less degenerative disease process is suspected to be present in this subset of patients...
Brain MRI lesion load at 1.5T and 3T versus clinical status in multiple sclerosisJames M Stankiewicz
Department of Neurology, Brigham and Women s Hospital, Partners MS Center, Harvard Medical School, Brookline, Massachusetts 02445, USA
J Neuroimaging 21:e50-6. 2011..To assess correlation between brain lesions and clinical status with 1.5T and 3T magnetic resonance imaging (MRI)...
Smoking and disease progression in multiple sclerosisBrian C Healy
Department of Neurology, Partners MS Center, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Arch Neurol 66:858-64. 2009..Although cigarette smokers are at increased risk of developing multiple sclerosis (MS), the effect of smoking on the progression of MS remains uncertain...
Magnetic resonance disease severity scale (MRDSS) for patients with multiple sclerosis: A longitudinal studyJennifer Moodie
Department of Neurology, University of Massachusetts, Boston, MA, USA
J Neurol Sci 315:49-54. 2012..We previously described a composite MRI scale combining T1-lesions, T2-lesions and whole brain atrophy in multiple sclerosis (MS): the magnetic resonance disease severity scale (MRDSS)...
A putative Alzheimer's disease risk allele in PCK1 influences brain atrophy in multiple sclerosisZongqi Xia
Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Brigham and Women s Hospital, Boston, Massachusetts, United States of America
PLoS ONE 5:e14169. 2010..We used a candidate gene approach to address whether genetic variants implicated in susceptibility to late onset Alzheimer's Disease (AD) influence brain volume and cognition in MS patients...
Deep gray matter involvement on brain MRI scans is associated with clinical progression in multiple sclerosisMohit Neema
Department of Neurology, Brigham and Women s Hospital, Partners MS Center, Harvard Medical School, Boston, Massachusetts 02115, USA
J Neuroimaging 19:3-8. 2009..Conventional brain MRI lesion measures have unreliable associations with clinical progression in multiple sclerosis (MS). Gray matter imaging may improve clinical-MRI correlations...
A method for evaluating treatment switching criteria in multiple sclerosisBrian C Healy
Partners Multiple Sclerosis Center, Department of Neurology, Brigham and Women s Hospital, Boston, MA, USA
Mult Scler 16:1483-9. 2010..We investigated a method to evaluate a treatment switching approach, namely treatment change after one multiple sclerosis (MS) relapse...
A model for the comprehensive investigation of a chronic autoimmune disease: the multiple sclerosis CLIMB studySusan A Gauthier
Partners Multiple Sclerosis Center, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA
Autoimmun Rev 5:532-6. 2006..Advances in our ability to clinically measure and monitor the disease through MRI imaging technology, immunology, and genetic analysis provide the opportunity to address these critical questions...
Predicting short-term disability in multiple sclerosisS A Gauthier
Partners Multiple Sclerosis Center, Brigham and Women s Hospital, Brookline, MA 02445, USA
Neurology 68:2059-65. 2007..To develop covariate specific short-term disability curves to demonstrate the probability of progressing by Expanded Disability Status Scale (EDSS) at semiannual visits...
Lateralized cognitive dysfunction in patients with systemic lupus erythematosusB I Glanz
Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA
Lupus 14:896-902. 2005..The observed deficits were not clearly attributable to vascular lesions and suggest immune-mediated effects on specific brain regions in a subgroup of patients with SLE...
