Research Topics
| Drew EndySummaryAffiliation: Massachusetts Institute of Technology Country: USA Publications
Research Grants
| Collaborators
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Detail Information
Publications
Measuring the activity of BioBrick promoters using an in vivo reference standardJason R Kelly
Department of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, 68 580, Cambridge Massachusetts 02139, USA
J Biol Eng 3:4. 2009..Additional in vivo reference standards for other types of biological functions would seem likely to have similar utility, and could thus improve research on the design, production, and reuse of standard biological parts...
Engineering BioBrick vectors from BioBrick partsReshma P Shetty
Department of Biological Engineering, MIT, 32 Vassar Street Rm 32 311, Cambridge, MA 02139, USA
J Biol Eng 2:5. 2008..Parts that conform to the BioBrick assembly standard are BioBrick standard biological parts. To date, over 2,000 BioBrick parts have been contributed to, and are available from, the Registry of Standard Biological Parts...
TABASCO: A single molecule, base-pair resolved gene expression simulatorSriram Kosuri
Department of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, MA 02139 USA
BMC Bioinformatics 8:480. 2007..However, for practical reasons including computational tractability, available simulators have not been able to represent genome-scale models of gene expression at this level of detail...
Genomics. Reconstruction of the genomesDrew Endy
Biological Engineering Department, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Science 319:1196-7. 2008
Foundations for engineering biologyDrew Endy
Division of Biological Engineering, Massachusetts Institute of Technology, Room 68 580, Koch Biology Building, 31 Ames Street, Cambridge, Massachusetts 02139, USA
Nature 438:449-53. 2005..Vibrant, open research communities and strategic leadership are necessary to ensure that the development and application of biological technologies remains overwhelmingly constructive...
Refactoring bacteriophage T7Leon Y Chan
Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Mol Syst Biol 1:2005.0018. 2005..The viability of our initial design suggests that the genomes encoding natural biological systems can be systematically redesigned and built anew in service of scientific understanding or human intention...
Signal transduction. Decoding NF-kappaB signalingAlice Y Ting
Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Science 298:1189-90. 2002
Stimulus design for model selection and validation in cell signalingJoshua F Apgar
Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
PLoS Comput Biol 4:e30. 2008..Taken together, these results provide a strong basis for using designed input stimuli as a tool for the development of cell signaling models...
Refinement and standardization of synthetic biological parts and devicesBarry Canton
Department of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave, 68 580, Cambridge, Massachusetts 02139, USA
Nat Biotechnol 26:787-93. 2008..The process of refinement and characterization leading to the BBa_F2620 datasheet may serve as a starting template for producing many standardized genetically encoded objects...
Determination of cell fate selection during phage lambda infectionFrançois St-Pierre
Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Proc Natl Acad Sci U S A 105:20705-10. 2008..Other cell fate decisions now thought to be stochastic might also be determined by pre-existing variation...
Engineering life: building a fab for biologyDavid Baker
University of Washington, USA
Sci Am 294:44-51. 2006
Synthetic genomics | options for governanceMichele S Garfinkel
J. Craig Venter Institute, Rockville, Maryland, USA
Biosecur Bioterror 5:359-62. 2007
Research Grants
- Dynamics, Control, and Design of Bacteriophage T7Drew Endy; Fiscal Year: 2007....
